NO307827B1 - Benzoxazole and pyridine derivatives, their use and pharmaceutical preparations containing them - Google Patents

Benzoxazole and pyridine derivatives, their use and pharmaceutical preparations containing them

Info

Publication number
NO307827B1
NO307827B1 NO970373A NO970373A NO307827B1 NO 307827 B1 NO307827 B1 NO 307827B1 NO 970373 A NO970373 A NO 970373A NO 970373 A NO970373 A NO 970373A NO 307827 B1 NO307827 B1 NO 307827B1
Authority
NO
Norway
Prior art keywords
benzoxazole
pharmaceutical preparations
preparations containing
pyridine derivatives
pyridine
Prior art date
Application number
NO970373A
Other languages
Norwegian (no)
Other versions
NO970373L (en
NO970373D0 (en
Inventor
David Haigh
Harshad Kantilal Rami
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9415330A external-priority patent/GB9415330D0/en
Priority claimed from GBGB9425599.9A external-priority patent/GB9425599D0/en
Priority claimed from GBGB9509923.0A external-priority patent/GB9509923D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of NO970373D0 publication Critical patent/NO970373D0/en
Publication of NO970373L publication Critical patent/NO970373L/en
Publication of NO307827B1 publication Critical patent/NO307827B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO970373A 1994-07-29 1997-01-28 Benzoxazole and pyridine derivatives, their use and pharmaceutical preparations containing them NO307827B1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9415330A GB9415330D0 (en) 1994-07-29 1994-07-29 Novel compounds
GBGB9425599.9A GB9425599D0 (en) 1994-12-19 1994-12-19 Novel compounds
GBGB9509923.0A GB9509923D0 (en) 1995-05-17 1995-05-17 Novel compounds
PCT/GB1995/001323 WO1996004261A1 (en) 1994-07-29 1995-06-07 Benzoxazoles and pryridine derivatives useful in the treatment of the type ii diabetes
PCT/EP1995/003038 WO1996004260A1 (en) 1994-07-29 1995-07-28 Benzoxazoles and pyridine derivatives useful in the treatment of the type ii diabetes

Publications (3)

Publication Number Publication Date
NO970373D0 NO970373D0 (en) 1997-01-28
NO970373L NO970373L (en) 1997-03-18
NO307827B1 true NO307827B1 (en) 2000-06-05

Family

ID=27267309

Family Applications (1)

Application Number Title Priority Date Filing Date
NO970373A NO307827B1 (en) 1994-07-29 1997-01-28 Benzoxazole and pyridine derivatives, their use and pharmaceutical preparations containing them

Country Status (16)

Country Link
EP (1) EP0772605A1 (en)
AP (1) AP776A (en)
BR (1) BR9508468A (en)
CA (1) CA2196079A1 (en)
CZ (1) CZ25497A3 (en)
DZ (1) DZ1916A1 (en)
FI (1) FI970357A (en)
HU (1) HUT76637A (en)
IL (3) IL114759A (en)
MA (1) MA23632A1 (en)
MX (1) MX9700763A (en)
NO (1) NO307827B1 (en)
OA (1) OA10470A (en)
PL (1) PL318766A1 (en)
SK (1) SK12297A3 (en)
WO (2) WO1996004261A1 (en)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9600464D0 (en) * 1996-01-09 1996-03-13 Smithkline Beecham Plc Novel method
CA2251468A1 (en) * 1996-04-04 1997-10-16 Sankyo Company, Limited Phenylalkylcarboxylic acid derivatives
US6160000A (en) * 1996-12-23 2000-12-12 Merck & Co., Inc. Antidiabetic agents based on aryl and heteroarylacetic acids
US6090839A (en) * 1996-12-23 2000-07-18 Merck & Co., Inc. Antidiabetic agents
BR9813019A (en) 1997-10-02 2000-09-05 Sankyo Co Derivatives of amidocarboxylic acid, agents for lowering blood glucose, reducing lipid, for improving insulin resistance, anti-inflammatory, for immuno-regulation, for inhibiting aldose reductase, for inhibiting 5-lipoxygenase, for the generation of suppressor of lipid peroxide, to activate ppar, to reduce osteoporosis, and compositions for the therapy or prevention of diabetes mellitus, hyperlipemia, obesity, impaired glucose tolerance, insulin resistance other than igt, liver fatty, diabetic complications, arteriosclerosis, gestational diabetes mellitus, polycystic ovary syndrome, arthroesthesis, rheumatoid arthritis, allergic diseases, asthma, cancer, autoimmune diseases, pancreatitis, and cataracts
CN1280574A (en) 1997-10-27 2001-01-17 雷迪研究基金会 New heterocyclic compounds and their use in medicine, process for their prepartion and pharmaceutical compositions containing them
BR9812770A (en) 1997-10-27 2000-12-12 Reddy Research Foundation Bicyclic compounds, process for their preparation and pharmaceutical compositions containing the same
US6440961B1 (en) 1997-10-27 2002-08-27 Dr. Reddy's Research Foundation Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
US6369067B1 (en) 1997-10-27 2002-04-09 Dr. Reddy's Research Foundation Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
WO1999019313A1 (en) * 1997-10-27 1999-04-22 Dr. Reddy's Research Foundation Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them
US6265401B1 (en) 1997-10-27 2001-07-24 Reddy-Cheminor, Inc. Bicyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them
US6444816B1 (en) 1997-10-27 2002-09-03 Dr. Reddy's Research Foundation Fused 7-oxo-pyrimidinyl compounds, preparation, composition and use thereof
KR100517644B1 (en) * 1997-10-27 2005-09-28 닥터 레디스 레보러터리즈 리미티드 Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them
NZ504106A (en) * 1998-05-27 2003-02-28 Dr Fused Oxazine, Thiazine and pipyridine compounds, process for their preparation and pharmaceutical compositions containing them
HUP0104108A2 (en) 1998-09-17 2002-03-28 Bristol-Myers Squibb Company Method for treating diabetes employing an ap2 inhibitor and combination
US6468996B1 (en) 1998-10-21 2002-10-22 Novo Nordisk A/S Substituted hetero-polycyclic compounds as PPARα and PPARγ activators
US6300339B1 (en) 1998-10-21 2001-10-09 Novo Nordisk A/S Compounds, their preparation and use
US6248781B1 (en) 1998-10-21 2001-06-19 Novo Nordisk A/S Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR)
US6214820B1 (en) 1998-10-21 2001-04-10 Novo Nordisk A/S Compounds, their preparation and use
JP2002527502A (en) * 1998-10-21 2002-08-27 ノボ ノルディスク アクティーゼルスカブ New compounds, their preparation and use
JP2002527501A (en) 1998-10-21 2002-08-27 ノボ ノルディスク アクティーゼルスカブ New compounds, their production and use
US6365586B1 (en) 1998-10-21 2002-04-02 Novo Nordisk A/S Compounds, their preparation and use
EP1123297A1 (en) * 1998-10-21 2001-08-16 Novo Nordisk A/S New compounds, their preparation and use
EP1123279A1 (en) * 1998-10-21 2001-08-16 Novo Nordisk A/S New compounds, their preparation and use
AU6325599A (en) * 1998-10-21 2000-05-08 Dr. Reddy's Research Foundation New compounds, their preparation and use
JP2002527503A (en) * 1998-10-21 2002-08-27 ノボ ノルディスク アクティーゼルスカブ New compounds, their preparation and use
US6531596B1 (en) 1998-10-29 2003-03-11 Dr. Reddy's Laboratories Ltd. Process for the preparation of new antidiabetic agents
WO2000026200A1 (en) 1998-10-29 2000-05-11 Dr. Reddy's Research Foundation An improved process for the preparation of new antidiabetic agents
WO2000063193A1 (en) * 1999-04-16 2000-10-26 Dr. Reddy's Research Foundation Novel polymorphic forms of an antidiabetic agent: process for their preparation and a pharmaceutical composition containing them
US7414128B2 (en) 1999-04-20 2008-08-19 Dr. Reddy's Laboratories, Limited Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate
US6369055B1 (en) 1999-04-20 2002-04-09 Novo Nordisk A/S Compounds, their preparation and use
US6274608B1 (en) 1999-04-20 2001-08-14 Novo Nordisk A/S Compounds, their preparation and use
CZ20013558A3 (en) * 1999-04-20 2002-05-15 Novo Nordisk A/S Compound, pharmaceutical preparation, treatment method, preparation and use thereof
US6972294B1 (en) 1999-04-20 2005-12-06 Novo Nordisk, A/S Compounds, their preparation and use
JP2002542237A (en) * 1999-04-20 2002-12-10 ノボ ノルディスク アクティーゼルスカブ New compounds, their production and use
WO2000063209A1 (en) * 1999-04-20 2000-10-26 Novo Nordisk A/S New compounds, their preparation and use
CZ20013832A3 (en) * 1999-04-28 2002-04-17 Dr. Reddy's Research Foundation Substituted bicyclic heterocyclic compounds, process of their preparation and their use as agents reducing obesity and hypocholesterolaemic agents
AU7073400A (en) 1999-08-27 2001-03-26 Eli Lilly And Company Biaryl-oxa(thia)zole derivatives and their use as ppars modulators
BRPI0108024B8 (en) * 2000-01-19 2021-05-25 Cadila Healthcare Ltd compound, process for preparing a compound, pharmaceutical composition, use of the compound, new intermediate and process for preparing a new intermediate
US6555577B1 (en) 2000-01-28 2003-04-29 Novo Nordisk A/S Compounds, their preparation and use
BR0107902A (en) * 2000-01-28 2002-11-05 Novo Nordisk As Compound, pharmaceutical composition, methods for treating diseases, and for the treatment and / or prevention of, conditions mediated by nuclear receptors, and diabetes and / or obesity, use of a compound, process for preparing a compound, and, method for treating type i diabetes, type ii diabetes, impaired glucose tolerance, insulin resistance or obesity
US6569901B2 (en) 2000-01-28 2003-05-27 Novo Nordisk A/S Alkynyl-substituted propionic acid derivatives, their preparation and use
US6509374B2 (en) 2000-04-17 2003-01-21 Novo Nordisk A/S Compounds, their preparation and use
EP1280783A2 (en) * 2000-05-12 2003-02-05 Ortho-McNeil Pharmaceutical, Inc. Methods of treatment using benzoxazinones as peroxisome proliferator activated receptor gamma modulators
ES2288957T3 (en) 2000-05-12 2008-02-01 Ortho-Mcneil Pharmaceutical, Inc. 4H-BENZO (1.4) OXAZIN-3-INA BIOLOGICALLY ACTIVE.
US6599899B2 (en) 2000-05-12 2003-07-29 Ortho-Mcneil Pharmaceutical, Inc. Benzoxazinones as peroxisome proliferator activated receptor gamma modulators and method of treatment
US6908908B2 (en) 2000-05-12 2005-06-21 Ortho-Mcneil Pharmaceutical, Inc. Biologically active 4H-benzo [1,4] oxazin-3-ones
US6987123B2 (en) * 2001-07-26 2006-01-17 Cadila Healthcare Limited Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine
US6869967B2 (en) 2001-07-30 2005-03-22 Novo Nordisk A/S Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives
US7067530B2 (en) 2001-07-30 2006-06-27 Novo Nordisk A/S Compounds, their preparation and use
US7220877B2 (en) 2001-10-17 2007-05-22 Novo Nordisk A/S Compounds, their preparation and use
AU2002351752A1 (en) 2001-12-29 2003-07-30 Novo Nordisk A/S Combined use of a glp-1 compound and another drug for treating dyslipidemia
US7015345B2 (en) 2002-02-21 2006-03-21 Asahi Kasei Pharma Corporation Propionic acid derivatives
US7816385B2 (en) 2002-12-20 2010-10-19 High Point Pharmaceuticals, Llc Dimeric dicarboxylic acid derivatives, their preparation and use
US6653334B1 (en) 2002-12-27 2003-11-25 Kowa Co., Ltd. Benzoxazole compound and pharmaceutical composition containing the same
JPWO2008139879A1 (en) * 2007-04-26 2010-07-29 ファルマフロンティア株式会社 G protein-coupled receptor inhibitor and pharmaceutical
CN103354757A (en) 2011-01-31 2013-10-16 卡迪拉保健有限公司 Treatment for lipodystrophy
JP6246895B2 (en) 2013-04-22 2017-12-13 カディラ・ヘルスケア・リミテッド Novel composition for non-alcoholic fatty liver disease (NAFLD)
ES2889916T3 (en) 2013-05-30 2022-01-14 Cadila Healthcare Ltd A procedure for the preparation of pyrroles with hypolipidemic and hypocholesteremic activities
TW201636015A (en) 2013-07-05 2016-10-16 卡地拉保健有限公司 Synergistic compositions
IN2013MU02470A (en) 2013-07-25 2015-06-26 Cadila Healthcare Ltd
IN2013MU02905A (en) 2013-09-06 2015-07-03 Cadila Healthcare Ltd
US10385017B2 (en) 2015-10-14 2019-08-20 Cadila Healthcare Limited Pyrrole compound, compositions and process for preparation thereof
JP6840853B2 (en) 2016-12-09 2021-03-10 カディラ・ヘルスケア・リミテッド Treatment of primary biliary cholangitis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5089514A (en) * 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents
NZ253742A (en) * 1992-07-03 1997-06-24 Smithkline Beecham Plc Heterocyclylaminoalkoxy substituted phenyl derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
IL114759A0 (en) 1995-12-31
SK12297A3 (en) 1997-08-06
FI970357A (en) 1997-03-26
CA2196079A1 (en) 1996-02-15
HUT76637A (en) 1997-10-28
MX9700763A (en) 1997-05-31
CZ25497A3 (en) 1997-09-17
IL125525A0 (en) 1999-03-12
OA10470A (en) 2002-04-08
MA23632A1 (en) 1996-04-01
DZ1916A1 (en) 2002-02-17
IL114759A (en) 1999-10-28
IL125525A (en) 2000-02-29
FI970357A0 (en) 1997-01-28
WO1996004261A1 (en) 1996-02-15
NO970373L (en) 1997-03-18
AP9700918A0 (en) 1997-01-31
EP0772605A1 (en) 1997-05-14
AP776A (en) 1999-10-28
NO970373D0 (en) 1997-01-28
WO1996004260A1 (en) 1996-02-15
BR9508468A (en) 1997-11-25
PL318766A1 (en) 1997-07-07

Similar Documents

Publication Publication Date Title
NO307827B1 (en) Benzoxazole and pyridine derivatives, their use and pharmaceutical preparations containing them
NO2009028I1 (en) Kinazoline derivatives, their use and preparation, and pharmaceutical preparations
NO308298B1 (en) Substituted quinazoline derivatives, their use and pharmaceutical preparations containing them
NO307707B1 (en) Spiroazabicyclic compounds, pharmaceutical preparations containing such compounds and their use
NO306401B1 (en) Oxazolidinedione derivatives, pharmaceutical preparations containing such derivatives, and their use
DK0826673T3 (en) Acetamide derivatives, processes for their preparation and medical preparations
NO305952B1 (en) 1,5-benzodiazepine derivatives, their use and pharmaceutical preparations
NO965103L (en) Bicyclic aromatic compounds, their use, and pharmaceutical and cosmetic preparations
DK0835246T3 (en) Aromatic compounds and pharmaceutical preparations containing them
IS3720A7 (en) Dialkoxy-pyridinyl-benzimidazole derivatives, their method and pharmaceutical use
NO993868D0 (en) 3-piperidyl-4-oxoquinazoline derivatives and medical preparations containing them
DK0847388T3 (en) Heterocyclic substituted biphenylamide derivatives, their preparation and their use as fungicides
NO303388B1 (en) Indole derivatives, pharmaceutical preparations containing them and intermediates in their preparation
NO961274D0 (en) Azole derivatives and pharmaceutical preparations thereof
DK0729956T3 (en) Benzothilphene Compounds, Substances, Preparations and Methods
CY2013003I1 (en) PHOSPHONOCHEMICAL DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND USE THEREOF
NO307092B1 (en) Sordaridine derivatives, their use and pharmaceutical composition
NO305075B1 (en) Glycinamide derivatives, pharmaceutical surfactants containing them and intermediates for their preparation
NO20010031D0 (en) Derivatives of 2-aminopyridines, their use as drugs and pharmaceutical preparations containing them
NO990215L (en) Synthetic polysaccharides, their method of preparation and pharmaceutical mixtures containing the same
NO965102L (en) Bicyclic aromatic compounds, uses thereof, and pharmaceutical and cosmetic preparations
NO983261D0 (en) New Benzoylguanidine Derivatives, Methods of Preparing Them and Using Them in the Preparation of Medicines
NO994659D0 (en) New pyridine derivatives and pharmaceutical preparations containing them
NO983472D0 (en) Taxoids, their preparation and pharmaceutical preparations containing the taxoids
NO973980D0 (en) Imiadazole derivatives and medical preparations

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN JANUARY 2003