NO307827B1 - Benzoxazole and pyridine derivatives, their use and pharmaceutical preparations containing them - Google Patents

Benzoxazole and pyridine derivatives, their use and pharmaceutical preparations containing them

Info

Publication number
NO307827B1
NO307827B1 NO970373A NO970373A NO307827B1 NO 307827 B1 NO307827 B1 NO 307827B1 NO 970373 A NO970373 A NO 970373A NO 970373 A NO970373 A NO 970373A NO 307827 B1 NO307827 B1 NO 307827B1
Authority
NO
Norway
Prior art keywords
benzoxazole
pharmaceutical preparations
preparations containing
pyridine derivatives
pyridine
Prior art date
Application number
NO970373A
Other languages
Norwegian (no)
Other versions
NO970373D0 (en
NO970373L (en
Inventor
David Haigh
Harshad Kantilal Rami
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9415330A external-priority patent/GB9415330D0/en
Priority claimed from GBGB9425599.9A external-priority patent/GB9425599D0/en
Priority claimed from GBGB9509923.0A external-priority patent/GB9509923D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of NO970373D0 publication Critical patent/NO970373D0/en
Publication of NO970373L publication Critical patent/NO970373L/en
Publication of NO307827B1 publication Critical patent/NO307827B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO970373A 1994-07-29 1997-01-28 Benzoxazole and pyridine derivatives, their use and pharmaceutical preparations containing them NO307827B1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9415330A GB9415330D0 (en) 1994-07-29 1994-07-29 Novel compounds
GBGB9425599.9A GB9425599D0 (en) 1994-12-19 1994-12-19 Novel compounds
GBGB9509923.0A GB9509923D0 (en) 1995-05-17 1995-05-17 Novel compounds
PCT/GB1995/001323 WO1996004261A1 (en) 1994-07-29 1995-06-07 Benzoxazoles and pryridine derivatives useful in the treatment of the type ii diabetes
PCT/EP1995/003038 WO1996004260A1 (en) 1994-07-29 1995-07-28 Benzoxazoles and pyridine derivatives useful in the treatment of the type ii diabetes

Publications (3)

Publication Number Publication Date
NO970373D0 NO970373D0 (en) 1997-01-28
NO970373L NO970373L (en) 1997-03-18
NO307827B1 true NO307827B1 (en) 2000-06-05

Family

ID=27267309

Family Applications (1)

Application Number Title Priority Date Filing Date
NO970373A NO307827B1 (en) 1994-07-29 1997-01-28 Benzoxazole and pyridine derivatives, their use and pharmaceutical preparations containing them

Country Status (16)

Country Link
EP (1) EP0772605A1 (en)
AP (1) AP776A (en)
BR (1) BR9508468A (en)
CA (1) CA2196079A1 (en)
CZ (1) CZ25497A3 (en)
DZ (1) DZ1916A1 (en)
FI (1) FI970357A (en)
HU (1) HUT76637A (en)
IL (3) IL125525A (en)
MA (1) MA23632A1 (en)
MX (1) MX9700763A (en)
NO (1) NO307827B1 (en)
OA (1) OA10470A (en)
PL (1) PL318766A1 (en)
SK (1) SK12297A3 (en)
WO (2) WO1996004261A1 (en)

Families Citing this family (64)

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GB9600464D0 (en) * 1996-01-09 1996-03-13 Smithkline Beecham Plc Novel method
WO1997037970A1 (en) * 1996-04-04 1997-10-16 Sankyo Company, Limited Phenylalkylcarboxylic acid derivatives
US6090839A (en) * 1996-12-23 2000-07-18 Merck & Co., Inc. Antidiabetic agents
US6160000A (en) * 1996-12-23 2000-12-12 Merck & Co., Inc. Antidiabetic agents based on aryl and heteroarylacetic acids
HUP0003881A3 (en) 1997-10-02 2001-04-28 Sankyo Co Amidocarboxylic acid derivatives
WO1999019313A1 (en) * 1997-10-27 1999-04-22 Dr. Reddy's Research Foundation Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them
CA2307068C (en) 1997-10-27 2007-04-10 Dr. Reddy's Research Foundation Bicyclic compounds, process for their preparation and pharmaceutical compositions containing them
CN100376560C (en) * 1997-10-27 2008-03-26 雷迪实验室有限公司 New tricyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them
US6369067B1 (en) 1997-10-27 2002-04-09 Dr. Reddy's Research Foundation Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
US6130214A (en) 1997-10-27 2000-10-10 Dr. Reddy's Research Foundation Benzothiazin and benzoxazin derivatives; their preparation and uses
US6444816B1 (en) 1997-10-27 2002-09-03 Dr. Reddy's Research Foundation Fused 7-oxo-pyrimidinyl compounds, preparation, composition and use thereof
US6265401B1 (en) * 1997-10-27 2001-07-24 Reddy-Cheminor, Inc. Bicyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them
US6440961B1 (en) 1997-10-27 2002-08-27 Dr. Reddy's Research Foundation Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
CN100357281C (en) * 1998-05-27 2007-12-26 雷迪实验室有限公司 Bicyclic compounds, process for their preparation and pharmaceutical composition containing them
CA2344300A1 (en) 1998-09-17 2000-03-23 Jeffrey A. Robl Method for treating atherosclerosis employing an ap2 inhibitor and combination
EP1123268A1 (en) * 1998-10-21 2001-08-16 Novo Nordisk A/S New compounds, their preparation and use
AU6325599A (en) * 1998-10-21 2000-05-08 Dr. Reddy's Research Foundation New compounds, their preparation and use
JP2002527507A (en) * 1998-10-21 2002-08-27 ノボ ノルディスク アクティーゼルスカブ New compounds, their preparation and use
AU6325799A (en) * 1998-10-21 2000-05-08 Dr. Reddy's Research Foundation New compounds, their preparation and use
US6300339B1 (en) 1998-10-21 2001-10-09 Novo Nordisk A/S Compounds, their preparation and use
EP1123267A1 (en) 1998-10-21 2001-08-16 Novo Nordisk A/S New compounds, their preparation and use
US6365586B1 (en) 1998-10-21 2002-04-02 Novo Nordisk A/S Compounds, their preparation and use
US6468996B1 (en) 1998-10-21 2002-10-22 Novo Nordisk A/S Substituted hetero-polycyclic compounds as PPARα and PPARγ activators
US6214820B1 (en) 1998-10-21 2001-04-10 Novo Nordisk A/S Compounds, their preparation and use
US6248781B1 (en) 1998-10-21 2001-06-19 Novo Nordisk A/S Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR)
AU6325899A (en) * 1998-10-21 2000-05-08 Dr. Reddy's Research Foundation New compounds, their preparation and use
US6531596B1 (en) 1998-10-29 2003-03-11 Dr. Reddy's Laboratories Ltd. Process for the preparation of new antidiabetic agents
AU763087B2 (en) 1998-10-29 2003-07-10 Dr. Reddy's Laboratories Limited An improved process for the preparation of new antidiabetic agents
WO2000063193A1 (en) * 1999-04-16 2000-10-26 Dr. Reddy's Research Foundation Novel polymorphic forms of an antidiabetic agent: process for their preparation and a pharmaceutical composition containing them
US6369055B1 (en) 1999-04-20 2002-04-09 Novo Nordisk A/S Compounds, their preparation and use
EP1171438A1 (en) * 1999-04-20 2002-01-16 Novo Nordisk A/S Compounds, their preparation and use
US6274608B1 (en) 1999-04-20 2001-08-14 Novo Nordisk A/S Compounds, their preparation and use
US7414128B2 (en) 1999-04-20 2008-08-19 Dr. Reddy's Laboratories, Limited Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate
WO2000063153A1 (en) * 1999-04-20 2000-10-26 Novo Nordisk A/S New compounds, their preparation and use
AU3957900A (en) * 1999-04-20 2000-11-02 Novo Nordisk A/S New compounds, their preparation and use
US6972294B1 (en) 1999-04-20 2005-12-06 Novo Nordisk, A/S Compounds, their preparation and use
EP1175412A1 (en) 1999-04-28 2002-01-30 Dr. Reddy's Research Foundation Substituted bicyclic heterocycles, process for their preparation and their use as antiobesity and hypocholesterolemic agents
DK1206457T3 (en) 1999-08-27 2004-02-16 Lilly Co Eli Biaryl-oxa (thia) zole derivatives and their use as modulators PPAPs
CA2397828C (en) * 2000-01-19 2007-09-04 Cadila Healthcare Ltd. Compounds having hypolipidemic and hypocholesteremic activities, process for their preparation and pharmaceutical compositions containing them
US6555577B1 (en) 2000-01-28 2003-04-29 Novo Nordisk A/S Compounds, their preparation and use
US6569901B2 (en) 2000-01-28 2003-05-27 Novo Nordisk A/S Alkynyl-substituted propionic acid derivatives, their preparation and use
HUP0204247A3 (en) * 2000-01-28 2003-10-28 Novo Nordisk As Alkynylsubstituted propionic acid derivatives and their use against diabetes and obesity
US6509374B2 (en) 2000-04-17 2003-01-21 Novo Nordisk A/S Compounds, their preparation and use
EP1280783A2 (en) * 2000-05-12 2003-02-05 Ortho-McNeil Pharmaceutical, Inc. Methods of treatment using benzoxazinones as peroxisome proliferator activated receptor gamma modulators
US6599899B2 (en) 2000-05-12 2003-07-29 Ortho-Mcneil Pharmaceutical, Inc. Benzoxazinones as peroxisome proliferator activated receptor gamma modulators and method of treatment
US6908908B2 (en) 2000-05-12 2005-06-21 Ortho-Mcneil Pharmaceutical, Inc. Biologically active 4H-benzo [1,4] oxazin-3-ones
ATE365725T1 (en) 2000-05-12 2007-07-15 Ortho Mcneil Pharm Inc BIOLOGICALLY ACTIVE 4H-BENZO 1,4ÖOXAZIN-3-ONE
US6987123B2 (en) 2001-07-26 2006-01-17 Cadila Healthcare Limited Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine
US6869967B2 (en) 2001-07-30 2005-03-22 Novo Nordisk A/S Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives
US7067530B2 (en) 2001-07-30 2006-06-27 Novo Nordisk A/S Compounds, their preparation and use
US7220877B2 (en) 2001-10-17 2007-05-22 Novo Nordisk A/S Compounds, their preparation and use
WO2003059378A2 (en) 2001-12-29 2003-07-24 Novo Nordisk A/S Combined use of a glp-1 compound and another drug for treating dyslipidemia
US7015345B2 (en) 2002-02-21 2006-03-21 Asahi Kasei Pharma Corporation Propionic acid derivatives
US7816385B2 (en) 2002-12-20 2010-10-19 High Point Pharmaceuticals, Llc Dimeric dicarboxylic acid derivatives, their preparation and use
US6653334B1 (en) 2002-12-27 2003-11-25 Kowa Co., Ltd. Benzoxazole compound and pharmaceutical composition containing the same
WO2008139879A1 (en) * 2007-04-26 2008-11-20 Pharmafrontier, Co., Ltd. G protein-coupled receptor inhibitor and pharmaceutical product
UA110813C2 (en) 2011-01-31 2016-02-25 Каділа Хелткере Лімітед Treatment of lipodystrophy
CN105377246B (en) 2013-04-22 2018-03-20 卡迪拉保健有限公司 For non-alcohol fatty liver (NAFLD) new compositions
WO2014195967A2 (en) 2013-05-30 2014-12-11 Cadila Healthcare Limited A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities
TW201513857A (en) 2013-07-05 2015-04-16 Cadila Healthcare Ltd Synergistic compositions
IN2013MU02470A (en) 2013-07-25 2015-06-26 Cadila Healthcare Ltd
US10112898B2 (en) 2013-09-06 2018-10-30 Cadila Healthcare Limited Process for the preparation of saroglitazar pharmaceutical salts
US10385017B2 (en) 2015-10-14 2019-08-20 Cadila Healthcare Limited Pyrrole compound, compositions and process for preparation thereof
ES2894261T3 (en) 2016-12-09 2022-02-14 Cadila Healthcare Ltd Treatment of primary biliary cholangitis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5089514A (en) * 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents
NZ253742A (en) * 1992-07-03 1997-06-24 Smithkline Beecham Plc Heterocyclylaminoalkoxy substituted phenyl derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
FI970357A0 (en) 1997-01-28
EP0772605A1 (en) 1997-05-14
AP776A (en) 1999-10-28
IL114759A (en) 1999-10-28
CA2196079A1 (en) 1996-02-15
NO970373D0 (en) 1997-01-28
WO1996004260A1 (en) 1996-02-15
IL125525A0 (en) 1999-03-12
NO970373L (en) 1997-03-18
IL125525A (en) 2000-02-29
OA10470A (en) 2002-04-08
CZ25497A3 (en) 1997-09-17
BR9508468A (en) 1997-11-25
FI970357A (en) 1997-03-26
IL114759A0 (en) 1995-12-31
AP9700918A0 (en) 1997-01-31
DZ1916A1 (en) 2002-02-17
WO1996004261A1 (en) 1996-02-15
HUT76637A (en) 1997-10-28
MA23632A1 (en) 1996-04-01
MX9700763A (en) 1997-05-31
PL318766A1 (en) 1997-07-07
SK12297A3 (en) 1997-08-06

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Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN JANUARY 2003