FI970357A - Benzoxazole and pyridine derivatives useful in the treatment of type II diabetes - Google Patents
Benzoxazole and pyridine derivatives useful in the treatment of type II diabetes Download PDFInfo
- Publication number
- FI970357A FI970357A FI970357A FI970357A FI970357A FI 970357 A FI970357 A FI 970357A FI 970357 A FI970357 A FI 970357A FI 970357 A FI970357 A FI 970357A FI 970357 A FI970357 A FI 970357A
- Authority
- FI
- Finland
- Prior art keywords
- benzoxazole
- diabetes
- treatment
- type
- pyridine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9415330A GB9415330D0 (en) | 1994-07-29 | 1994-07-29 | Novel compounds |
GBGB9425599.9A GB9425599D0 (en) | 1994-12-19 | 1994-12-19 | Novel compounds |
GBGB9509923.0A GB9509923D0 (en) | 1995-05-17 | 1995-05-17 | Novel compounds |
PCT/GB1995/001323 WO1996004261A1 (en) | 1994-07-29 | 1995-06-07 | Benzoxazoles and pryridine derivatives useful in the treatment of the type ii diabetes |
PCT/EP1995/003038 WO1996004260A1 (en) | 1994-07-29 | 1995-07-28 | Benzoxazoles and pyridine derivatives useful in the treatment of the type ii diabetes |
Publications (2)
Publication Number | Publication Date |
---|---|
FI970357A0 FI970357A0 (en) | 1997-01-28 |
FI970357A true FI970357A (en) | 1997-03-26 |
Family
ID=27267309
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI970357A FI970357A (en) | 1994-07-29 | 1997-01-28 | Benzoxazole and pyridine derivatives useful in the treatment of type II diabetes |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0772605A1 (en) |
AP (1) | AP776A (en) |
BR (1) | BR9508468A (en) |
CA (1) | CA2196079A1 (en) |
CZ (1) | CZ25497A3 (en) |
DZ (1) | DZ1916A1 (en) |
FI (1) | FI970357A (en) |
HU (1) | HUT76637A (en) |
IL (3) | IL125525A (en) |
MA (1) | MA23632A1 (en) |
MX (1) | MX9700763A (en) |
NO (1) | NO307827B1 (en) |
OA (1) | OA10470A (en) |
PL (1) | PL318766A1 (en) |
SK (1) | SK12297A3 (en) |
WO (2) | WO1996004261A1 (en) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9600464D0 (en) * | 1996-01-09 | 1996-03-13 | Smithkline Beecham Plc | Novel method |
DK0916651T3 (en) * | 1996-04-04 | 2003-12-01 | Sankyo Co | phenylalkylcarboxylic acid |
US6160000A (en) * | 1996-12-23 | 2000-12-12 | Merck & Co., Inc. | Antidiabetic agents based on aryl and heteroarylacetic acids |
US6090839A (en) * | 1996-12-23 | 2000-07-18 | Merck & Co., Inc. | Antidiabetic agents |
KR20010030881A (en) | 1997-10-02 | 2001-04-16 | 가와무라 요시부미 | Amidocarboxylic acid derivatives |
WO1999019313A1 (en) * | 1997-10-27 | 1999-04-22 | Dr. Reddy's Research Foundation | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them |
US6369067B1 (en) | 1997-10-27 | 2002-04-09 | Dr. Reddy's Research Foundation | Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
US6265401B1 (en) | 1997-10-27 | 2001-07-24 | Reddy-Cheminor, Inc. | Bicyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
US6440961B1 (en) | 1997-10-27 | 2002-08-27 | Dr. Reddy's Research Foundation | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
EP1124807A1 (en) * | 1997-10-27 | 2001-08-22 | Dr. Reddy's Research Foundation | Novel heterocyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
US6444816B1 (en) | 1997-10-27 | 2002-09-03 | Dr. Reddy's Research Foundation | Fused 7-oxo-pyrimidinyl compounds, preparation, composition and use thereof |
MXPA00004036A (en) | 1997-10-27 | 2006-05-24 | Reddys Lab Ltd Dr | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them. |
AU752059B2 (en) | 1997-10-27 | 2002-09-05 | Dr. Reddy's Laboratories Limited | Bicyclic compounds, process for their preparation and pharmaceutical compositions containing them |
PL341795A1 (en) * | 1998-05-27 | 2001-05-07 | Reddy Research Foundation | Bicycle compounds, process for obtaining them and pharmacological compositions containing such compounds |
SK3202001A3 (en) | 1998-09-17 | 2002-04-04 | Bristol Myers Squibb Co | Drug and a pharmaceutical composition for treating diabetes, insulin resistance, obesity, hyperglycemia, hyperinsulinemia or increased level |
JP2002527520A (en) * | 1998-10-21 | 2002-08-27 | ノボ ノルディスク アクティーゼルスカブ | New compounds, their production and use |
EP1123279A1 (en) * | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | New compounds, their preparation and use |
US6365586B1 (en) | 1998-10-21 | 2002-04-02 | Novo Nordisk A/S | Compounds, their preparation and use |
US6214820B1 (en) | 1998-10-21 | 2001-04-10 | Novo Nordisk A/S | Compounds, their preparation and use |
US6248781B1 (en) | 1998-10-21 | 2001-06-19 | Novo Nordisk A/S | Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR) |
AU6325599A (en) * | 1998-10-21 | 2000-05-08 | Dr. Reddy's Research Foundation | New compounds, their preparation and use |
US6300339B1 (en) | 1998-10-21 | 2001-10-09 | Novo Nordisk A/S | Compounds, their preparation and use |
US6468996B1 (en) | 1998-10-21 | 2002-10-22 | Novo Nordisk A/S | Substituted hetero-polycyclic compounds as PPARα and PPARγ activators |
JP2002527502A (en) * | 1998-10-21 | 2002-08-27 | ノボ ノルディスク アクティーゼルスカブ | New compounds, their preparation and use |
AU6325899A (en) * | 1998-10-21 | 2000-05-08 | Dr. Reddy's Research Foundation | New compounds, their preparation and use |
WO2000023415A1 (en) * | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | New compounds, their preparation and use |
JP2002528535A (en) * | 1998-10-29 | 2002-09-03 | ドクター・レディーズ・リサーチ・ファウンデーション | An improved method for producing new antidiabetic agents |
US6531596B1 (en) | 1998-10-29 | 2003-03-11 | Dr. Reddy's Laboratories Ltd. | Process for the preparation of new antidiabetic agents |
WO2000063193A1 (en) * | 1999-04-16 | 2000-10-26 | Dr. Reddy's Research Foundation | Novel polymorphic forms of an antidiabetic agent: process for their preparation and a pharmaceutical composition containing them |
EP1171431A1 (en) * | 1999-04-20 | 2002-01-16 | Novo Nordisk A/S | Compounds, their preparation and use |
HUP0200807A3 (en) * | 1999-04-20 | 2003-03-28 | Novo Nordisk As | Substituted propionic acid derivatives, process for their preparation, pharmaceutical compositions containing them and their use |
US6972294B1 (en) | 1999-04-20 | 2005-12-06 | Novo Nordisk, A/S | Compounds, their preparation and use |
US6369055B1 (en) | 1999-04-20 | 2002-04-09 | Novo Nordisk A/S | Compounds, their preparation and use |
WO2000063209A1 (en) * | 1999-04-20 | 2000-10-26 | Novo Nordisk A/S | New compounds, their preparation and use |
US7414128B2 (en) | 1999-04-20 | 2008-08-19 | Dr. Reddy's Laboratories, Limited | Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate |
US6274608B1 (en) | 1999-04-20 | 2001-08-14 | Novo Nordisk A/S | Compounds, their preparation and use |
TR200103848T2 (en) * | 1999-04-28 | 2002-04-22 | Dr. Reddy's Research Foundation | Substituted bicyclic heterocycles, their process for their preparation and their use for antiobesity and as hypocholesterolemic agents. |
WO2001016120A1 (en) | 1999-08-27 | 2001-03-08 | Eli Lilly And Company | Biaryl-oxa(thia)zole derivatives and their use as ppars modulators |
WO2001053257A2 (en) * | 2000-01-19 | 2001-07-26 | Cadila Healthcare Ltd. | Compounds having hypolipedemic and hypocholesteremic activities, process for their preparation and pharmaceutical compositions containing them |
US6569901B2 (en) | 2000-01-28 | 2003-05-27 | Novo Nordisk A/S | Alkynyl-substituted propionic acid derivatives, their preparation and use |
JP2003520839A (en) * | 2000-01-28 | 2003-07-08 | ノボ ノルディスク アクティーゼルスカブ | New compounds, their production and use |
US6555577B1 (en) | 2000-01-28 | 2003-04-29 | Novo Nordisk A/S | Compounds, their preparation and use |
US6509374B2 (en) | 2000-04-17 | 2003-01-21 | Novo Nordisk A/S | Compounds, their preparation and use |
US6908908B2 (en) | 2000-05-12 | 2005-06-21 | Ortho-Mcneil Pharmaceutical, Inc. | Biologically active 4H-benzo [1,4] oxazin-3-ones |
PT1280784E (en) * | 2000-05-12 | 2007-09-03 | Ortho Mcneil Pharm Inc | De |
US6599899B2 (en) | 2000-05-12 | 2003-07-29 | Ortho-Mcneil Pharmaceutical, Inc. | Benzoxazinones as peroxisome proliferator activated receptor gamma modulators and method of treatment |
AU2001261503A1 (en) * | 2000-05-12 | 2001-11-26 | Ortho-Mcneil Pharmaceutical, Inc. | Methods of treatment using benzoxazinones as peroxisome proliferator activated receptor gamma modulators |
US6987123B2 (en) * | 2001-07-26 | 2006-01-17 | Cadila Healthcare Limited | Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine |
US6869967B2 (en) | 2001-07-30 | 2005-03-22 | Novo Nordisk A/S | Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives |
US7067530B2 (en) | 2001-07-30 | 2006-06-27 | Novo Nordisk A/S | Compounds, their preparation and use |
US7220877B2 (en) | 2001-10-17 | 2007-05-22 | Novo Nordisk A/S | Compounds, their preparation and use |
WO2003059378A2 (en) | 2001-12-29 | 2003-07-24 | Novo Nordisk A/S | Combined use of a glp-1 compound and another drug for treating dyslipidemia |
US7015345B2 (en) | 2002-02-21 | 2006-03-21 | Asahi Kasei Pharma Corporation | Propionic acid derivatives |
US7816385B2 (en) | 2002-12-20 | 2010-10-19 | High Point Pharmaceuticals, Llc | Dimeric dicarboxylic acid derivatives, their preparation and use |
US6653334B1 (en) | 2002-12-27 | 2003-11-25 | Kowa Co., Ltd. | Benzoxazole compound and pharmaceutical composition containing the same |
WO2008139879A1 (en) * | 2007-04-26 | 2008-11-20 | Pharmafrontier, Co., Ltd. | G protein-coupled receptor inhibitor and pharmaceutical product |
AP3920A (en) | 2011-01-31 | 2016-12-02 | Cadila Healthcare Ltd | Treatment for lipodystrophy |
MA38385A1 (en) | 2013-04-22 | 2017-09-29 | Cadila Healthcare Ltd | New composition for non-alcoholic fatty liver disease (nafld) |
US20160107989A1 (en) | 2013-05-30 | 2016-04-21 | Cadila Healthcare Limited | A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities |
TW201636015A (en) | 2013-07-05 | 2016-10-16 | 卡地拉保健有限公司 | Synergistic compositions |
IN2013MU02470A (en) | 2013-07-25 | 2015-06-26 | Cadila Healthcare Ltd | |
WO2015033357A2 (en) | 2013-09-06 | 2015-03-12 | Cadila Healthcare Limited | An improved process for the preparation of pyrrole derivatives |
WO2017064635A2 (en) | 2015-10-14 | 2017-04-20 | Cadila Healthcare Limited | Pyrrole compound, compositions and process for preparation thereof |
EP3551180B1 (en) | 2016-12-09 | 2021-09-29 | Cadila Healthcare Limited | Treatment for primary biliary cholangitis |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5089514A (en) * | 1990-06-14 | 1992-02-18 | Pfizer Inc. | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
EP0648212B1 (en) * | 1992-07-03 | 2001-10-24 | Smithkline Beecham Plc | Benzoxazole and benzothiazole derivatives as pharmaceutical |
-
1995
- 1995-06-07 BR BR9508468A patent/BR9508468A/en unknown
- 1995-06-07 WO PCT/GB1995/001323 patent/WO1996004261A1/en active Search and Examination
- 1995-07-26 DZ DZ950094A patent/DZ1916A1/en active
- 1995-07-27 MA MA23972A patent/MA23632A1/en unknown
- 1995-07-27 IL IL12552595A patent/IL125525A/en unknown
- 1995-07-27 IL IL11475995A patent/IL114759A/en unknown
- 1995-07-28 AP APAP/P/1997/000918A patent/AP776A/en active
- 1995-07-28 MX MX9700763A patent/MX9700763A/en unknown
- 1995-07-28 HU HU9700264A patent/HUT76637A/en unknown
- 1995-07-28 SK SK122-97A patent/SK12297A3/en unknown
- 1995-07-28 WO PCT/EP1995/003038 patent/WO1996004260A1/en not_active Application Discontinuation
- 1995-07-28 CA CA002196079A patent/CA2196079A1/en not_active Abandoned
- 1995-07-28 PL PL95318766A patent/PL318766A1/en unknown
- 1995-07-28 EP EP95930436A patent/EP0772605A1/en not_active Withdrawn
- 1995-07-28 CZ CZ97254A patent/CZ25497A3/en unknown
-
1997
- 1997-01-28 FI FI970357A patent/FI970357A/en unknown
- 1997-01-28 NO NO970373A patent/NO307827B1/en not_active IP Right Cessation
- 1997-01-29 OA OA60957A patent/OA10470A/en unknown
-
1998
- 1998-07-27 IL IL12552598A patent/IL125525A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP0772605A1 (en) | 1997-05-14 |
OA10470A (en) | 2002-04-08 |
CA2196079A1 (en) | 1996-02-15 |
NO307827B1 (en) | 2000-06-05 |
WO1996004260A1 (en) | 1996-02-15 |
IL114759A (en) | 1999-10-28 |
IL114759A0 (en) | 1995-12-31 |
DZ1916A1 (en) | 2002-02-17 |
NO970373L (en) | 1997-03-18 |
PL318766A1 (en) | 1997-07-07 |
BR9508468A (en) | 1997-11-25 |
AP776A (en) | 1999-10-28 |
IL125525A (en) | 2000-02-29 |
CZ25497A3 (en) | 1997-09-17 |
IL125525A0 (en) | 1999-03-12 |
AP9700918A0 (en) | 1997-01-31 |
FI970357A0 (en) | 1997-01-28 |
HUT76637A (en) | 1997-10-28 |
WO1996004261A1 (en) | 1996-02-15 |
SK12297A3 (en) | 1997-08-06 |
MX9700763A (en) | 1997-05-31 |
NO970373D0 (en) | 1997-01-28 |
MA23632A1 (en) | 1996-04-01 |
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