SK118498A3 - Novel erythromycin derivatives, method for preparing same, and use thereof as drugs - Google Patents

Novel erythromycin derivatives, method for preparing same, and use thereof as drugs Download PDF

Info

Publication number
SK118498A3
SK118498A3 SK1184-98A SK118498A SK118498A3 SK 118498 A3 SK118498 A3 SK 118498A3 SK 118498 A SK118498 A SK 118498A SK 118498 A3 SK118498 A3 SK 118498A3
Authority
SK
Slovakia
Prior art keywords
formula
compounds
group
methyl
dideoxy
Prior art date
Application number
SK1184-98A
Other languages
English (en)
Slovak (sk)
Inventor
Constantin Agouridas
Jean-Francois Chantot
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of SK118498A3 publication Critical patent/SK118498A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
SK1184-98A 1996-02-28 1997-02-27 Novel erythromycin derivatives, method for preparing same, and use thereof as drugs SK118498A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9602472A FR2745290B1 (fr) 1996-02-28 1996-02-28 Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
PCT/FR1997/000351 WO1997031929A1 (fr) 1996-02-28 1997-02-27 Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number Publication Date
SK118498A3 true SK118498A3 (en) 1999-07-12

Family

ID=9489659

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1184-98A SK118498A3 (en) 1996-02-28 1997-02-27 Novel erythromycin derivatives, method for preparing same, and use thereof as drugs

Country Status (31)

Country Link
US (1) US6096714A (xx)
EP (1) EP0885234B1 (xx)
JP (1) JP4102440B2 (xx)
KR (1) KR100486053B1 (xx)
CN (1) CN1168734C (xx)
AP (1) AP952A (xx)
AR (1) AR005999A1 (xx)
AT (1) ATE217633T1 (xx)
AU (1) AU716204B2 (xx)
BG (1) BG63207B1 (xx)
BR (1) BR9707709B1 (xx)
CZ (1) CZ293893B6 (xx)
DE (1) DE69712610T2 (xx)
DK (1) DK0885234T3 (xx)
EA (1) EA001376B1 (xx)
EE (1) EE9800265A (xx)
ES (1) ES2176698T3 (xx)
FR (1) FR2745290B1 (xx)
HU (1) HU227567B1 (xx)
IL (1) IL125622A (xx)
NO (1) NO983955L (xx)
NZ (1) NZ331600A (xx)
OA (1) OA10845A (xx)
PL (1) PL191736B1 (xx)
PT (1) PT885234E (xx)
SK (1) SK118498A3 (xx)
TR (1) TR199801713T2 (xx)
UA (1) UA58504C2 (xx)
WO (1) WO1997031929A1 (xx)
YU (1) YU37098A (xx)
ZA (1) ZA971659B (xx)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA989835B (en) * 1997-10-29 1999-05-05 Taisho Pharmaceutical Co Ltd Erythromycin a derivatives
WO1999021870A1 (en) * 1997-10-29 1999-05-06 Taisho Pharmaceutical Co., Ltd. Erythromycin a 11, 12-carbamate derivatives
FR2780977B1 (fr) * 1998-07-09 2000-09-01 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
JP4573925B2 (ja) * 1998-07-09 2010-11-04 アベンティス・ファーマ・ソシエテ・アノニム 新規のエリスロマイシン誘導体、その製造方法及びその薬剤としての使用
FR2792637B1 (fr) * 1999-04-26 2001-06-01 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2781484B1 (fr) * 1998-07-21 2001-08-10 Hoechst Marion Roussel Inc Nouveaux derives de la 6-deoxy erythromycine, leur procede de preparation et leur application comme medicaments
DK1147121T3 (da) 1999-01-27 2004-04-13 Pfizer Prod Inc Ketolidantibiotika
SK15162001A3 (sk) * 1999-05-24 2003-02-04 Pfizer Products Inc. Deriváty 13-metylerytromycínu
AU6183700A (en) * 1999-08-06 2001-03-05 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
WO2001010880A1 (fr) * 1999-08-06 2001-02-15 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
AU6316400A (en) * 1999-08-06 2001-03-05 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
EP1146051A3 (en) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
US20020115621A1 (en) * 2000-08-07 2002-08-22 Wei-Gu Su Macrolide antibiotics
ITMI20021726A1 (it) 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
CA2529817C (en) 2003-03-10 2013-02-12 Optimer Pharmaceuticals, Inc. Novel antibacterial agents
WO2005007143A2 (en) * 2003-07-14 2005-01-27 The Board Of Trustees Of The University Of Illinois Use of makrolides and ketolides for the treatment of tuberculosis
WO2007069264A2 (en) * 2005-12-15 2007-06-21 Alembic Limited Reference standards for determining the purity of telithromycin and processes therefor
JP5698979B2 (ja) * 2007-10-25 2015-04-08 センプラ ファーマシューティカルズ，インコーポレイテッド マクロライド系抗菌剤の調製プロセス
JP5602748B2 (ja) 2008-10-24 2014-10-08 センプラ ファーマシューティカルズ，インコーポレイテッド トリアゾール含有マクロライドを用いた生体防御
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
ES2608285T3 (es) 2009-09-10 2017-04-07 Cempra Pharmaceuticals, Inc. Procedimientos para el tratamiento de paludismo, tuberculosis y enfermedades por MAC
DK2550286T3 (en) 2010-03-22 2016-02-29 Cempra Pharmaceuticals Inc CRYSTALLINE FORMS OF A MACROLID AND APPLICATIONS THEREOF
BR112012029586A2 (pt) 2010-05-20 2016-08-02 Cempra Pharmaceuticals Inc processos para preparar macrolídeos e cetolídeos e intermediários dos mesmos
JP6042334B2 (ja) 2010-09-10 2016-12-14 センプラ ファーマシューティカルズ，インコーポレイテッド 疾患治療のための水素結合形成フルオロケトライド
US10188674B2 (en) 2012-03-27 2019-01-29 Cempra Pharmaceuticals, Inc. Parenteral formulations for administering macrolide antibiotics
JP6426696B2 (ja) 2013-03-14 2018-11-21 センプラ ファーマシューティカルズ，インコーポレイテッド 呼吸器疾患の治療のための方法および製剤
US9751908B2 (en) 2013-03-15 2017-09-05 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US487411A (en) * 1892-12-06 Island
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
US5444031A (en) * 1993-01-21 1995-08-22 Calgon Carbon Corporation Process for making catalytic carbon
FR2727969B1 (fr) * 1994-12-09 1997-01-17 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
TR199801713T2 (xx) 1998-12-21
FR2745290A1 (fr) 1997-08-29
PL191736B1 (pl) 2006-06-30
AP9801318A0 (en) 1998-09-30
AP952A (en) 2001-03-29
CN1168734C (zh) 2004-09-29
EP0885234A1 (fr) 1998-12-23
AR005999A1 (es) 1999-07-21
ZA971659B (en) 1998-02-26
EE9800265A (et) 1999-02-15
AU1929897A (en) 1997-09-16
KR19990087324A (ko) 1999-12-27
AU716204B2 (en) 2000-02-24
HU227567B1 (en) 2011-08-29
BR9707709B1 (pt) 2014-10-14
OA10845A (fr) 2003-02-05
DK0885234T3 (da) 2002-08-26
JP2000505469A (ja) 2000-05-09
BR9707709A (pt) 1999-04-06
ATE217633T1 (de) 2002-06-15
JP4102440B2 (ja) 2008-06-18
YU37098A (sh) 1999-07-28
UA58504C2 (uk) 2003-08-15
EP0885234B1 (fr) 2002-05-15
US6096714A (en) 2000-08-01
FR2745290B1 (fr) 1998-04-03
IL125622A0 (en) 1999-04-11
DE69712610T2 (de) 2002-11-28
WO1997031929A1 (fr) 1997-09-04
EA199800768A1 (ru) 1999-02-25
IL125622A (en) 2003-10-31
HUP9902576A3 (en) 2001-03-28
ES2176698T3 (es) 2002-12-01
HUP9902576A1 (hu) 1999-12-28
NZ331600A (en) 1999-08-30
PT885234E (pt) 2002-10-31
EA001376B1 (ru) 2001-02-26
CZ258798A3 (cs) 1998-12-16
BG102691A (en) 1999-06-30
KR100486053B1 (ko) 2005-06-16
PL328608A1 (en) 1999-02-01
NO983955D0 (no) 1998-08-27
CN1212700A (zh) 1999-03-31
CZ293893B6 (cs) 2004-08-18
DE69712610D1 (de) 2002-06-20
BG63207B1 (bg) 2001-06-29
NO983955L (no) 1998-08-27

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