NO983955L - Nye erytromycinderivater, metode for fremstilling av disse og anvendelse derav som legemidler - Google Patents

Nye erytromycinderivater, metode for fremstilling av disse og anvendelse derav som legemidler

Info

Publication number
NO983955L
NO983955L NO983955A NO983955A NO983955L NO 983955 L NO983955 L NO 983955L NO 983955 A NO983955 A NO 983955A NO 983955 A NO983955 A NO 983955A NO 983955 L NO983955 L NO 983955L
Authority
NO
Norway
Prior art keywords
pharmaceuticals
preparation
erythromycin derivatives
new erythromycin
radical
Prior art date
Application number
NO983955A
Other languages
English (en)
Other versions
NO983955D0 (no
Inventor
Constantin Agouridas
Jean-Fran Ois Chantot
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of NO983955D0 publication Critical patent/NO983955D0/no
Publication of NO983955L publication Critical patent/NO983955L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Forbindelser av formel (I) O OZ (D hvori X er et CH2- eller SO2-radikal eller et oksygenatom, Y er et (CH2 )¿- (CH=CH )n( CH2 )0-radikal hvor m -t- n + o S 8, n - O eller l, Ar er et arylradikal, og W er et hydrogenatom eller en karbamatfunksjonsrest, er be- skrevet. Forbindelsene av formel (I) har verdifulle antibiotiske egenskaper.
NO983955A 1996-02-28 1998-08-27 Nye erytromycinderivater, metode for fremstilling av disse og anvendelse derav som legemidler NO983955L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9602472A FR2745290B1 (fr) 1996-02-28 1996-02-28 Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
PCT/FR1997/000351 WO1997031929A1 (fr) 1996-02-28 1997-02-27 Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
NO983955D0 NO983955D0 (no) 1998-08-27
NO983955L true NO983955L (no) 1998-08-27

Family

ID=9489659

Family Applications (1)

Application Number Title Priority Date Filing Date
NO983955A NO983955L (no) 1996-02-28 1998-08-27 Nye erytromycinderivater, metode for fremstilling av disse og anvendelse derav som legemidler

Country Status (31)

Country Link
US (1) US6096714A (no)
EP (1) EP0885234B1 (no)
JP (1) JP4102440B2 (no)
KR (1) KR100486053B1 (no)
CN (1) CN1168734C (no)
AP (1) AP952A (no)
AR (1) AR005999A1 (no)
AT (1) ATE217633T1 (no)
AU (1) AU716204B2 (no)
BG (1) BG63207B1 (no)
BR (1) BR9707709B1 (no)
CZ (1) CZ293893B6 (no)
DE (1) DE69712610T2 (no)
DK (1) DK0885234T3 (no)
EA (1) EA001376B1 (no)
EE (1) EE9800265A (no)
ES (1) ES2176698T3 (no)
FR (1) FR2745290B1 (no)
HU (1) HU227567B1 (no)
IL (1) IL125622A (no)
NO (1) NO983955L (no)
NZ (1) NZ331600A (no)
OA (1) OA10845A (no)
PL (1) PL191736B1 (no)
PT (1) PT885234E (no)
SK (1) SK118498A3 (no)
TR (1) TR199801713T2 (no)
UA (1) UA58504C2 (no)
WO (1) WO1997031929A1 (no)
YU (1) YU37098A (no)
ZA (1) ZA971659B (no)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999021870A1 (en) * 1997-10-29 1999-05-06 Taisho Pharmaceutical Co., Ltd. Erythromycin a 11, 12-carbamate derivatives
ZA989835B (en) * 1997-10-29 1999-05-05 Taisho Pharmaceutical Co Ltd Erythromycin a derivatives
JP4573925B2 (ja) * 1998-07-09 2010-11-04 アベンティス・ファーマ・ソシエテ・アノニム 新規のエリスロマイシン誘導体、その製造方法及びその薬剤としての使用
FR2792637B1 (fr) * 1999-04-26 2001-06-01 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2780977B1 (fr) * 1998-07-09 2000-09-01 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2781484B1 (fr) * 1998-07-21 2001-08-10 Hoechst Marion Roussel Inc Nouveaux derives de la 6-deoxy erythromycine, leur procede de preparation et leur application comme medicaments
KR20020002380A (ko) 1999-01-27 2002-01-09 실버스타인 아써 에이. 케톨라이드 항생물질
EA200100983A1 (ru) * 1999-05-24 2002-10-31 Пфайзер Продактс Инк. Производные 13-метилэритромицина
AU6183700A (en) * 1999-08-06 2001-03-05 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
WO2001010879A1 (en) * 1999-08-06 2001-02-15 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
WO2001010880A1 (fr) * 1999-08-06 2001-02-15 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
EP1146051A3 (en) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
US20020115621A1 (en) * 2000-08-07 2002-08-22 Wei-Gu Su Macrolide antibiotics
ITMI20021726A1 (it) * 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
WO2004080391A2 (en) 2003-03-10 2004-09-23 Optimer Pharmaceuticals, Inc. Novel antibacterial agents
US20050014706A1 (en) * 2003-07-14 2005-01-20 Kanakeshwari Falzari Method of treating tuberculosis
WO2007069264A2 (en) * 2005-12-15 2007-06-21 Alembic Limited Reference standards for determining the purity of telithromycin and processes therefor
CA2703475A1 (en) 2007-10-25 2009-04-30 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
EP2358379B1 (en) * 2008-10-24 2015-12-16 Cempra Pharmaceuticals, Inc. Biodefenses using triazole-containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
US9480679B2 (en) 2009-09-10 2016-11-01 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
PL2550286T3 (pl) 2010-03-22 2016-07-29 Cempra Pharmaceuticals Inc Krystaliczne postaci makrolidu i ich zastosowanie
CN102917708B (zh) 2010-05-20 2015-11-25 森普拉制药公司 制备大环内酯和酮内酯及其中间体的方法
US9815863B2 (en) 2010-09-10 2017-11-14 Cempra Pharmaceuticals, Inc. Hydrogen bond forming fluoro ketolides for treating diseases
CN104470527B (zh) 2012-03-27 2019-05-28 森普拉制药公司 用于施用大环内酯抗生素的肠胃外制剂
WO2014152326A1 (en) 2013-03-14 2014-09-25 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
US9751908B2 (en) 2013-03-15 2017-09-05 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US487411A (en) * 1892-12-06 Island
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of the history of erythromycin
US5444031A (en) * 1993-01-21 1995-08-22 Calgon Carbon Corporation Process for making catalytic carbon
FR2727969B1 (fr) * 1994-12-09 1997-01-17 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
FR2745290A1 (fr) 1997-08-29
NZ331600A (en) 1999-08-30
JP2000505469A (ja) 2000-05-09
AU1929897A (en) 1997-09-16
JP4102440B2 (ja) 2008-06-18
KR19990087324A (ko) 1999-12-27
BR9707709B1 (pt) 2014-10-14
CZ258798A3 (cs) 1998-12-16
DK0885234T3 (da) 2002-08-26
NO983955D0 (no) 1998-08-27
PL191736B1 (pl) 2006-06-30
DE69712610D1 (de) 2002-06-20
DE69712610T2 (de) 2002-11-28
HU227567B1 (en) 2011-08-29
EA001376B1 (ru) 2001-02-26
ES2176698T3 (es) 2002-12-01
HUP9902576A3 (en) 2001-03-28
AP952A (en) 2001-03-29
HUP9902576A1 (hu) 1999-12-28
AR005999A1 (es) 1999-07-21
EA199800768A1 (ru) 1999-02-25
CZ293893B6 (cs) 2004-08-18
OA10845A (fr) 2003-02-05
EP0885234B1 (fr) 2002-05-15
YU37098A (sh) 1999-07-28
KR100486053B1 (ko) 2005-06-16
PL328608A1 (en) 1999-02-01
ATE217633T1 (de) 2002-06-15
EE9800265A (et) 1999-02-15
BG63207B1 (bg) 2001-06-29
US6096714A (en) 2000-08-01
ZA971659B (en) 1998-02-26
CN1168734C (zh) 2004-09-29
BG102691A (en) 1999-06-30
EP0885234A1 (fr) 1998-12-23
AU716204B2 (en) 2000-02-24
IL125622A (en) 2003-10-31
AP9801318A0 (en) 1998-09-30
SK118498A3 (en) 1999-07-12
UA58504C2 (uk) 2003-08-15
BR9707709A (pt) 1999-04-06
FR2745290B1 (fr) 1998-04-03
TR199801713T2 (xx) 1998-12-21
WO1997031929A1 (fr) 1997-09-04
CN1212700A (zh) 1999-03-31
IL125622A0 (en) 1999-04-11
PT885234E (pt) 2002-10-31

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Legal Events

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