ES2176698T3 - Nuevos derivados de la eritromicina, su procedimiento de preparacion y su aplicacion como medicamentos. - Google Patents

Nuevos derivados de la eritromicina, su procedimiento de preparacion y su aplicacion como medicamentos.

Info

Publication number
ES2176698T3
ES2176698T3 ES97907141T ES97907141T ES2176698T3 ES 2176698 T3 ES2176698 T3 ES 2176698T3 ES 97907141 T ES97907141 T ES 97907141T ES 97907141 T ES97907141 T ES 97907141T ES 2176698 T3 ES2176698 T3 ES 2176698T3
Authority
ES
Spain
Prior art keywords
erythromycin
medicines
application
preparation procedure
new derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97907141T
Other languages
English (en)
Inventor
Constantin Agouridas
Jean-Francois Chantot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Application granted granted Critical
Publication of ES2176698T3 publication Critical patent/ES2176698T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A LOS COMPUESTOS DE FORMULA (I), EN LA CUAL: X REPRESENTA UN RADICAL CH 2 O SO 2 O UN ATOMO DE OXIGENO; Y REPRESENTA UN RADICAL (CH 2 ) M (CH = CH) N)(CH 2 ) O , CON M + N + O 8, N = 0 O 1; AR REPRESENTA UN RADICAL ARILO; Y W REPRESENTA UN ATOMO DE HIDROGENO O EL RESTO DE UNA FUNCION CARBAMATO. LOS COMPUESTOS DE FORMULA (I) PRESENTAN INTERESANTES PROPIEDADES ANTIBIOTICAS.
ES97907141T 1996-02-28 1997-02-27 Nuevos derivados de la eritromicina, su procedimiento de preparacion y su aplicacion como medicamentos. Expired - Lifetime ES2176698T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9602472A FR2745290B1 (fr) 1996-02-28 1996-02-28 Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number Publication Date
ES2176698T3 true ES2176698T3 (es) 2002-12-01

Family

ID=9489659

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97907141T Expired - Lifetime ES2176698T3 (es) 1996-02-28 1997-02-27 Nuevos derivados de la eritromicina, su procedimiento de preparacion y su aplicacion como medicamentos.

Country Status (31)

Country Link
US (1) US6096714A (es)
EP (1) EP0885234B1 (es)
JP (1) JP4102440B2 (es)
KR (1) KR100486053B1 (es)
CN (1) CN1168734C (es)
AP (1) AP952A (es)
AR (1) AR005999A1 (es)
AT (1) ATE217633T1 (es)
AU (1) AU716204B2 (es)
BG (1) BG63207B1 (es)
BR (1) BR9707709B1 (es)
CZ (1) CZ293893B6 (es)
DE (1) DE69712610T2 (es)
DK (1) DK0885234T3 (es)
EA (1) EA001376B1 (es)
EE (1) EE9800265A (es)
ES (1) ES2176698T3 (es)
FR (1) FR2745290B1 (es)
HU (1) HU227567B1 (es)
IL (1) IL125622A (es)
NO (1) NO983955L (es)
NZ (1) NZ331600A (es)
OA (1) OA10845A (es)
PL (1) PL191736B1 (es)
PT (1) PT885234E (es)
SK (1) SK118498A3 (es)
TR (1) TR199801713T2 (es)
UA (1) UA58504C2 (es)
WO (1) WO1997031929A1 (es)
YU (1) YU37098A (es)
ZA (1) ZA971659B (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA989830B (en) * 1997-10-29 1999-05-04 Taisho Pharmaceutical Co Ltd Erythromycin a derivatives
WO1999021869A1 (en) * 1997-10-29 1999-05-06 Taisho Pharmaceutical Co., Ltd. Erythromycin a, 11,12-carbamate derivatives
JP4573925B2 (ja) * 1998-07-09 2010-11-04 アベンティス・ファーマ・ソシエテ・アノニム 新規のエリスロマイシン誘導体、その製造方法及びその薬剤としての使用
FR2792637B1 (fr) * 1999-04-26 2001-06-01 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2780977B1 (fr) * 1998-07-09 2000-09-01 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2781484B1 (fr) * 1998-07-21 2001-08-10 Hoechst Marion Roussel Inc Nouveaux derives de la 6-deoxy erythromycine, leur procede de preparation et leur application comme medicaments
KR20020002380A (ko) 1999-01-27 2002-01-09 실버스타인 아써 에이. 케톨라이드 항생물질
AU3832100A (en) * 1999-05-24 2000-12-12 Pfizer Products Inc. 13-methyl-erythromycin derivatives
AU6316400A (en) * 1999-08-06 2001-03-05 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
WO2001010878A1 (fr) * 1999-08-06 2001-02-15 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
AU6183800A (en) * 1999-08-06 2001-03-05 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
EP1146051A3 (en) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
US20020115621A1 (en) * 2000-08-07 2002-08-22 Wei-Gu Su Macrolide antibiotics
ITMI20021726A1 (it) 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
WO2004080391A2 (en) 2003-03-10 2004-09-23 Optimer Pharmaceuticals, Inc. Novel antibacterial agents
US20050014706A1 (en) * 2003-07-14 2005-01-20 Kanakeshwari Falzari Method of treating tuberculosis
WO2007069264A2 (en) * 2005-12-15 2007-06-21 Alembic Limited Reference standards for determining the purity of telithromycin and processes therefor
AU2008316830B2 (en) * 2007-10-25 2016-03-17 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
WO2010048600A1 (en) * 2008-10-24 2010-04-29 Cempra Pharmaceuticals, Inc. Methods for treating resistant diseases using triazole containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
ES2608285T3 (es) 2009-09-10 2017-04-07 Cempra Pharmaceuticals, Inc. Procedimientos para el tratamiento de paludismo, tuberculosis y enfermedades por MAC
RU2650883C2 (ru) 2010-03-22 2018-04-18 Семпра Фармасьютикалз, Инк. Кристаллические формы макролида и их применение
PL2571506T3 (pl) 2010-05-20 2017-10-31 Cempra Pharmaceuticals Inc Sposoby sporządzania makrolidów i ketolidów oraz ich produktów pośrednich
KR20180110181A (ko) 2010-09-10 2018-10-08 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
MX2014011537A (es) 2012-03-27 2015-02-10 Cempra Pharmaceuticals Inc Formulaciones parenterales para la administracion de antibioticos macrolidos.
EP2968801B1 (en) 2013-03-14 2018-09-26 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
AU2014233240B2 (en) 2013-03-15 2018-08-09 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US487411A (en) * 1892-12-06 Island
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of the history of erythromycin
US5444031A (en) * 1993-01-21 1995-08-22 Calgon Carbon Corporation Process for making catalytic carbon
FR2727969B1 (fr) * 1994-12-09 1997-01-17 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
HUP9902576A1 (hu) 1999-12-28
JP4102440B2 (ja) 2008-06-18
NO983955D0 (no) 1998-08-27
DE69712610D1 (de) 2002-06-20
CZ258798A3 (cs) 1998-12-16
AP9801318A0 (en) 1998-09-30
KR100486053B1 (ko) 2005-06-16
ZA971659B (en) 1998-02-26
AU1929897A (en) 1997-09-16
ATE217633T1 (de) 2002-06-15
DE69712610T2 (de) 2002-11-28
EP0885234B1 (fr) 2002-05-15
BR9707709A (pt) 1999-04-06
SK118498A3 (en) 1999-07-12
NO983955L (no) 1998-08-27
CZ293893B6 (cs) 2004-08-18
EE9800265A (et) 1999-02-15
PT885234E (pt) 2002-10-31
TR199801713T2 (xx) 1998-12-21
EA001376B1 (ru) 2001-02-26
EA199800768A1 (ru) 1999-02-25
YU37098A (sh) 1999-07-28
BR9707709B1 (pt) 2014-10-14
WO1997031929A1 (fr) 1997-09-04
DK0885234T3 (da) 2002-08-26
BG63207B1 (bg) 2001-06-29
HU227567B1 (en) 2011-08-29
IL125622A (en) 2003-10-31
AP952A (en) 2001-03-29
CN1168734C (zh) 2004-09-29
US6096714A (en) 2000-08-01
JP2000505469A (ja) 2000-05-09
EP0885234A1 (fr) 1998-12-23
FR2745290A1 (fr) 1997-08-29
BG102691A (en) 1999-06-30
PL328608A1 (en) 1999-02-01
AU716204B2 (en) 2000-02-24
CN1212700A (zh) 1999-03-31
KR19990087324A (ko) 1999-12-27
IL125622A0 (en) 1999-04-11
PL191736B1 (pl) 2006-06-30
FR2745290B1 (fr) 1998-04-03
AR005999A1 (es) 1999-07-21
OA10845A (fr) 2003-02-05
NZ331600A (en) 1999-08-30
HUP9902576A3 (en) 2001-03-28
UA58504C2 (uk) 2003-08-15

Similar Documents

Publication Publication Date Title
ES2176698T3 (es) Nuevos derivados de la eritromicina, su procedimiento de preparacion y su aplicacion como medicamentos.
ES2122472T3 (es) Derivados de eritromicina, su procedimiento de preparacion y su aplicacion como medicamentos.
DE69903988D1 (de) Fungizide Trifluorophenyltriazolopyrimidine
FI93831B (fi) Tetratsolit, jotka ovat verenpainetta alentavien yhdisteiden välituotteita
DE60015927D1 (en) Phenylharnstoff und phenylthioharnstoffderivate
PT1109812E (pt) Pirrolobenzodiazepinas
DE59709414D1 (de) Oxyiminopregnancarbolactone
IL123293A0 (en) Piperidine derivatives their preparation and use
MX9602837A (es) Composiciones cosmeticas o farmaceuticas que contienen mangiferina o sus derivados.
GR3036714T3 (en) Fungicidal trifluorophenyl-triazolopyrimidines
FI970417A (fi) Aryylitioyhdisteet bakteerien ja virusten vastaisina aineina
DE60228071D1 (de) Spiropyrazol-verbindungen
DK0923554T3 (da) N-Benzylpiperidin- og tetrahydropyridinderivater
NO20004978D0 (no) Semi-syntetiske ecteinascidiner
NO20014756D0 (no) C(10)-heterosubstituerte acetattaksaner som antitmormidler
ATE289810T1 (de) Ecteinascidinderivate
FI891283A0 (fi) Ifosfamid-mesna-lyofilisat och foerfarande foer dess framstaellning.
ES2190429T3 (es) Benciliden-quinuclidinonas como agentes protectores contra el sol.
ES2056153T3 (es) Expectorante que comprende un derivado hidroxialquilcisteina.
ATE296623T1 (de) Prolaktin-senkendes mittel
DK0660822T3 (da) Cykliske benzylamino-, benzylamido- og benzylimidoderivater som antipsykotiske midler
ES2174323T3 (es) Nuevos derivados de la eritromicina, su procedimiento de preparacion y su aplicacion como medicamentos.
ES2173556T3 (es) Nuevos compuestos heterociclicos, su procedimiento de preparacion y los compuestos farmaceuticos que los contienen.
ES2063324T3 (es) Derivados del acido butirico.
AR023374A1 (es) Derivados de 3-amino-3-arilpropano-1-ol. su preparacion y uso