ES2176698T3 - Nuevos derivados de la eritromicina, su procedimiento de preparacion y su aplicacion como medicamentos. - Google Patents

Nuevos derivados de la eritromicina, su procedimiento de preparacion y su aplicacion como medicamentos.

Info

Publication number
ES2176698T3
ES2176698T3 ES97907141T ES97907141T ES2176698T3 ES 2176698 T3 ES2176698 T3 ES 2176698T3 ES 97907141 T ES97907141 T ES 97907141T ES 97907141 T ES97907141 T ES 97907141T ES 2176698 T3 ES2176698 T3 ES 2176698T3
Authority
ES
Spain
Prior art keywords
erythromycin
medicines
application
preparation procedure
new derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97907141T
Other languages
English (en)
Inventor
Constantin Agouridas
Jean-Francois Chantot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Application granted granted Critical
Publication of ES2176698T3 publication Critical patent/ES2176698T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A LOS COMPUESTOS DE FORMULA (I), EN LA CUAL: X REPRESENTA UN RADICAL CH 2 O SO 2 O UN ATOMO DE OXIGENO; Y REPRESENTA UN RADICAL (CH 2 ) M (CH = CH) N)(CH 2 ) O , CON M + N + O 8, N = 0 O 1; AR REPRESENTA UN RADICAL ARILO; Y W REPRESENTA UN ATOMO DE HIDROGENO O EL RESTO DE UNA FUNCION CARBAMATO. LOS COMPUESTOS DE FORMULA (I) PRESENTAN INTERESANTES PROPIEDADES ANTIBIOTICAS.
ES97907141T 1996-02-28 1997-02-27 Nuevos derivados de la eritromicina, su procedimiento de preparacion y su aplicacion como medicamentos. Expired - Lifetime ES2176698T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9602472A FR2745290B1 (fr) 1996-02-28 1996-02-28 Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number Publication Date
ES2176698T3 true ES2176698T3 (es) 2002-12-01

Family

ID=9489659

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97907141T Expired - Lifetime ES2176698T3 (es) 1996-02-28 1997-02-27 Nuevos derivados de la eritromicina, su procedimiento de preparacion y su aplicacion como medicamentos.

Country Status (31)

Country Link
US (1) US6096714A (es)
EP (1) EP0885234B1 (es)
JP (1) JP4102440B2 (es)
KR (1) KR100486053B1 (es)
CN (1) CN1168734C (es)
AP (1) AP952A (es)
AR (1) AR005999A1 (es)
AT (1) ATE217633T1 (es)
AU (1) AU716204B2 (es)
BG (1) BG63207B1 (es)
BR (1) BR9707709B1 (es)
CZ (1) CZ293893B6 (es)
DE (1) DE69712610T2 (es)
DK (1) DK0885234T3 (es)
EA (1) EA001376B1 (es)
EE (1) EE9800265A (es)
ES (1) ES2176698T3 (es)
FR (1) FR2745290B1 (es)
HU (1) HU227567B1 (es)
IL (1) IL125622A (es)
NO (1) NO983955D0 (es)
NZ (1) NZ331600A (es)
OA (1) OA10845A (es)
PL (1) PL191736B1 (es)
PT (1) PT885234E (es)
SK (1) SK118498A3 (es)
TR (1) TR199801713T2 (es)
UA (1) UA58504C2 (es)
WO (1) WO1997031929A1 (es)
YU (1) YU37098A (es)
ZA (1) ZA971659B (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA989830B (en) * 1997-10-29 1999-05-04 Taisho Pharmaceutical Co Ltd Erythromycin a derivatives
WO1999021869A1 (en) * 1997-10-29 1999-05-06 Taisho Pharmaceutical Co., Ltd. Erythromycin a, 11,12-carbamate derivatives
FR2780977B1 (fr) * 1998-07-09 2000-09-01 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2792637B1 (fr) * 1999-04-26 2001-06-01 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
JP4573925B2 (ja) * 1998-07-09 2010-11-04 アベンティス・ファーマ・ソシエテ・アノニム 新規のエリスロマイシン誘導体、その製造方法及びその薬剤としての使用
FR2781484B1 (fr) * 1998-07-21 2001-08-10 Hoechst Marion Roussel Inc Nouveaux derives de la 6-deoxy erythromycine, leur procede de preparation et leur application comme medicaments
AP2001002222A0 (en) 1999-01-27 2001-09-30 Pfizer Prod Inc Ketolide antibiotics.
TR200103395T2 (tr) * 1999-05-24 2002-04-22 Pfizer Products Inc. 13-metil eritromisin türevleri.
AU6183700A (en) * 1999-08-06 2001-03-05 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
WO2001010879A1 (fr) * 1999-08-06 2001-02-15 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
WO2001010880A1 (fr) * 1999-08-06 2001-02-15 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
EP1146051A3 (en) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
US20020115621A1 (en) * 2000-08-07 2002-08-22 Wei-Gu Su Macrolide antibiotics
ITMI20021726A1 (it) 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
EP3738591A3 (en) 2003-03-10 2021-03-24 Merck Sharp & Dohme Corp. Novel antibacterial agents
WO2005007143A2 (en) * 2003-07-14 2005-01-27 The Board Of Trustees Of The University Of Illinois Use of makrolides and ketolides for the treatment of tuberculosis
WO2007069264A2 (en) * 2005-12-15 2007-06-21 Alembic Limited Reference standards for determining the purity of telithromycin and processes therefor
CN101917850B (zh) 2007-10-25 2016-01-13 森普拉制药公司 大环内酯类抗菌剂的制备方法
DK2358379T3 (en) * 2008-10-24 2016-03-07 Cempra Pharmaceuticals Inc BIOFORSVAR USING TRIAZOLHOLDIGE macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
EP2475253B1 (en) 2009-09-10 2016-10-26 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and mac diseases
BR112012023950A2 (pt) 2010-03-22 2016-07-05 Cempra Pharmaceuticals Inc formas cristalinas de um macrolídeo, e usos dos mesmos
PL2571506T3 (pl) 2010-05-20 2017-10-31 Cempra Pharmaceuticals Inc Sposoby sporządzania makrolidów i ketolidów oraz ich produktów pośrednich
US9815863B2 (en) 2010-09-10 2017-11-14 Cempra Pharmaceuticals, Inc. Hydrogen bond forming fluoro ketolides for treating diseases
MX2014011537A (es) 2012-03-27 2015-02-10 Cempra Pharmaceuticals Inc Formulaciones parenterales para la administracion de antibioticos macrolidos.
WO2014152326A1 (en) 2013-03-14 2014-09-25 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
BR112015023670A2 (pt) 2013-03-15 2017-07-18 Cempra Pharmaceuticals Inc processo para preparar um composto

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US487411A (en) * 1892-12-06 Island
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
US5444031A (en) * 1993-01-21 1995-08-22 Calgon Carbon Corporation Process for making catalytic carbon
FR2727969B1 (fr) * 1994-12-09 1997-01-17 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
UA58504C2 (uk) 2003-08-15
BR9707709B1 (pt) 2014-10-14
HUP9902576A1 (hu) 1999-12-28
NO983955L (no) 1998-08-27
US6096714A (en) 2000-08-01
TR199801713T2 (xx) 1998-12-21
WO1997031929A1 (fr) 1997-09-04
KR100486053B1 (ko) 2005-06-16
PL191736B1 (pl) 2006-06-30
ATE217633T1 (de) 2002-06-15
DE69712610T2 (de) 2002-11-28
BR9707709A (pt) 1999-04-06
AP952A (en) 2001-03-29
CN1168734C (zh) 2004-09-29
EA199800768A1 (ru) 1999-02-25
JP2000505469A (ja) 2000-05-09
EA001376B1 (ru) 2001-02-26
NO983955D0 (no) 1998-08-27
AU1929897A (en) 1997-09-16
CZ293893B6 (cs) 2004-08-18
FR2745290A1 (fr) 1997-08-29
IL125622A (en) 2003-10-31
AU716204B2 (en) 2000-02-24
EE9800265A (et) 1999-02-15
DK0885234T3 (da) 2002-08-26
HU227567B1 (en) 2011-08-29
PT885234E (pt) 2002-10-31
NZ331600A (en) 1999-08-30
JP4102440B2 (ja) 2008-06-18
OA10845A (fr) 2003-02-05
AR005999A1 (es) 1999-07-21
EP0885234B1 (fr) 2002-05-15
HUP9902576A3 (en) 2001-03-28
EP0885234A1 (fr) 1998-12-23
DE69712610D1 (de) 2002-06-20
CZ258798A3 (cs) 1998-12-16
PL328608A1 (en) 1999-02-01
SK118498A3 (en) 1999-07-12
AP9801318A0 (en) 1998-09-30
KR19990087324A (ko) 1999-12-27
CN1212700A (zh) 1999-03-31
BG102691A (en) 1999-06-30
IL125622A0 (en) 1999-04-11
FR2745290B1 (fr) 1998-04-03
ZA971659B (en) 1998-02-26
YU37098A (sh) 1999-07-28
BG63207B1 (bg) 2001-06-29

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