NO970175L - Pyrido-annellerte tienyl- og furanyl-oksazolidinoner - Google Patents

Pyrido-annellerte tienyl- og furanyl-oksazolidinoner

Info

Publication number
NO970175L
NO970175L NO970175A NO970175A NO970175L NO 970175 L NO970175 L NO 970175L NO 970175 A NO970175 A NO 970175A NO 970175 A NO970175 A NO 970175A NO 970175 L NO970175 L NO 970175L
Authority
NO
Norway
Prior art keywords
thienyl
canceled
pyrido
oxazolidinones
furanyl
Prior art date
Application number
NO970175A
Other languages
English (en)
Other versions
NO970175D0 (no
Inventor
Bernd Riedl
Dieter Haebich
Andreas Stolle
Martin Ruppelt
Stephan Bartel
Walter Guarnieri
Rainer Endermann
Hein-Peter Kroll
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NO970175D0 publication Critical patent/NO970175D0/no
Publication of NO970175L publication Critical patent/NO970175L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Det blir beskrevet nye pyrido-annellerte tienyl- og furanyloksazolidoner, med den generelle formel (1) 1 :^ 0 I ¿N' 'O X. (I) R' hvor A står for et oksygen- eller svovelatom eller for gruppen SO2, og D, E, G og L er Uke eller forskjellige og minst en av disse substituentene står for et nitrogenatom og de øvrige står for en rest med formelen -CR-, og r' står for azido, hydroksy eller for en gruppe med formelen -OR^*^, 0-S02R^' eller -NR12r13. Det blir også beskrevet en fremgangsmåte for fremstilling av disse forbindelsene samt deres anvendelse som legemiddel, spesielt som antibaknerielt legemiddel.
NO970175A 1996-01-16 1997-01-15 Pyrido-annellerte tienyl- og furanyl-oksazolidinoner NO970175L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19601264A DE19601264A1 (de) 1996-01-16 1996-01-16 Pyrido-annellierte Thienyl- und Furanyl-Oxazolidinone

Publications (2)

Publication Number Publication Date
NO970175D0 NO970175D0 (no) 1997-01-15
NO970175L true NO970175L (no) 1997-07-17

Family

ID=7782815

Family Applications (1)

Application Number Title Priority Date Filing Date
NO970175A NO970175L (no) 1996-01-16 1997-01-15 Pyrido-annellerte tienyl- og furanyl-oksazolidinoner

Country Status (23)

Country Link
US (1) US5827857A (no)
EP (1) EP0785200A3 (no)
JP (1) JPH09194482A (no)
KR (1) KR970059180A (no)
AU (1) AU1009897A (no)
BG (1) BG101132A (no)
BR (1) BR9700702A (no)
CA (1) CA2194938A1 (no)
CO (1) CO4520187A1 (no)
CZ (1) CZ12997A3 (no)
DE (1) DE19601264A1 (no)
EE (1) EE9700031A (no)
HR (1) HRP960615A2 (no)
HU (1) HU9700136D0 (no)
IL (1) IL119995A0 (no)
NO (1) NO970175L (no)
PL (1) PL317929A1 (no)
SG (1) SG50002A1 (no)
SK (1) SK5997A3 (no)
SV (1) SV1997000003A (no)
TN (1) TNSN97008A1 (no)
TR (1) TR199601001A1 (no)
ZA (1) ZA97303B (no)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
CA2288750A1 (en) * 1997-05-30 1998-12-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
US6255304B1 (en) 1997-05-30 2001-07-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
US6239152B1 (en) 1998-01-23 2001-05-29 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
AU3180999A (en) * 1998-02-25 1999-09-15 Pharmacia & Upjohn Company Substituted aminomethyl isoxazoline derivatives useful as antimicrobials
CN1311787A (zh) 1998-06-05 2001-09-05 阿斯特拉曾尼卡有限公司 噁唑烷酮衍生物、其制备方法以及含有它们的药物组合物
US6867203B2 (en) 1998-12-29 2005-03-15 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds
JP2003500397A (ja) * 1999-05-19 2003-01-07 スミスクライン ビーチャム パブリック リミテッド カンパニー Ｍｒｓ阻害剤としての２−ｎｈ−ピリドンおよびピリミドン
WO2001009107A1 (en) 1999-07-28 2001-02-08 Pharmacia & Upjohn Company Oxazolidinones and their use as antiinfectives
US6608081B2 (en) 1999-08-12 2003-08-19 Ortho-Mcneil Pharmaceutical, Inc. Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
US6297242B1 (en) 1999-08-12 2001-10-02 Ortho-Mcneil Pharmaceutical, Inc. N-substituted amidine and guanidine oxazolidinone antibacterials and methods of use thereof
US6413981B1 (en) 1999-08-12 2002-07-02 Ortho-Mcneil Pharamceutical, Inc. Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
US6518285B2 (en) 1999-12-21 2003-02-11 Ortho Mcneil Pharmaceutical, Inc. Piperidinyloxy and pyrrolidinyloxy oxazolidinone antibacterials
DE19962924A1 (de) 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
US6514529B2 (en) 2000-03-22 2003-02-04 Pharmacia & Upjohn Company Oxazolidinone tablet formulation
MY127336A (en) * 2000-03-22 2006-11-30 Upjohn Co Container for linezolid iv solution
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
WO2002002095A2 (en) 2000-06-30 2002-01-10 Pharmacia & Upjohn Company Compositions for treating bacterial infections containing oxazolidinone compound, sulbactam and an ampicillin
DE10129725A1 (de) 2001-06-20 2003-01-02 Bayer Ag Kombinationstherapie substituierter Oxazolidinone
TW200302095A (en) * 2002-01-25 2003-08-01 Upjohn Co Oxazolidinone cotherapy
US7141588B2 (en) * 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
IL164195A0 (en) * 2002-03-29 2005-12-18 Upjohn Co Parenteral, intravenous, and oral administration of oxazolidinones for treating diabetic foot infections
US6868358B2 (en) * 2002-07-24 2005-03-15 The Goodyear Tire & Rubber Company Method for processing information in a tire pressure monitoring system
DE60304360T2 (de) * 2002-08-12 2006-11-16 Pharmacia & Upjohn Co. Llc, Kalamazoo N-aryl-2-oxazolidinone und deren derivate
US7141570B2 (en) * 2002-11-21 2006-11-28 Pharmacia & Upjohn Company N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
DE10300111A1 (de) * 2003-01-07 2004-07-15 Bayer Healthcare Ag Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid
JP2006516989A (ja) * 2003-02-07 2006-07-13 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 抗菌剤として使用するための二環式環によりｎ−置換されたオキサゾリジノン誘導体
JP2006516991A (ja) * 2003-02-07 2006-07-13 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 抗菌剤
US20040204463A1 (en) * 2003-04-01 2004-10-14 Harris Christina Renee N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
JP2007503426A (ja) * 2003-08-25 2007-02-22 ワーナー−ランバート カンパニー リミティド ライアビリティー カンパニー 新規な抗微生物性アリールオキサゾリジノン化合物
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
DE10355461A1 (de) 2003-11-27 2005-06-23 Bayer Healthcare Ag Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung
DE102004062475A1 (de) * 2004-12-24 2006-07-06 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung
EP1685841A1 (en) 2005-01-31 2006-08-02 Bayer Health Care Aktiengesellschaft Prevention and treatment of thromboembolic disorders
US20070155738A1 (en) 2005-05-20 2007-07-05 Alantos Pharmaceuticals, Inc. Heterobicyclic metalloprotease inhibitors
DE102005045518A1 (de) 2005-09-23 2007-03-29 Bayer Healthcare Ag 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung
DE102005047558A1 (de) * 2005-10-04 2008-02-07 Bayer Healthcare Ag Kombinationstherapie substituierter Oxazolidinone zur Prophylaxe und Behandlung von cerebralen Durchblutungsstörungen
DE102005047561A1 (de) 2005-10-04 2007-04-05 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung
CA2823159C (en) 2005-10-04 2014-10-21 Bayer Intellectual Property Gmbh Polymorphic form of 5-chloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophenecarboxamide
TW200815428A (en) * 2006-08-15 2008-04-01 Wyeth Corp Oxazolidone derivatives as PR modulators
US7649007B2 (en) * 2006-08-15 2010-01-19 Wyeth Llc Oxazolidine derivatives as PR modulators
US7538107B2 (en) 2006-08-15 2009-05-26 Wyeth Oxazinan-2-one derivatives useful as PR modulators
WO2008021309A1 (en) * 2006-08-15 2008-02-21 Wyeth Imidazolidin-2-one derivatives useful as pr modulators
DE102006051625A1 (de) * 2006-11-02 2008-05-08 Bayer Materialscience Ag Kombinationstherapie substituierter Oxazolidinone
US7998992B2 (en) * 2007-03-30 2011-08-16 Institute Of Medicinal Molecular Design, Inc. Oxazolidinone derivative having inhibitory activity on 11β-hydroxysteroid dehydrogenase type 1

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH614711A5 (no) * 1975-04-08 1979-12-14 Sandoz Ag
US4705799A (en) 1983-06-07 1987-11-10 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
US4921869A (en) * 1987-10-09 1990-05-01 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US4965268A (en) * 1987-10-09 1990-10-23 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US5032605A (en) * 1987-10-09 1991-07-16 Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl oxa or thia cycloalkylbenzene derivatives useful as antibacterial agents
US4801600A (en) * 1987-10-09 1989-01-31 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US5254577A (en) * 1988-07-29 1993-10-19 The Du Pont Merck Pharmaceutical Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
US5164510A (en) * 1988-09-15 1992-11-17 The Upjohn Company 5'Indolinyl-5β-amidomethyloxazolidin-2-ones
WO1990002744A1 (en) * 1988-09-15 1990-03-22 The Upjohn Company In position 3 substituted-5-beta-amidomethyl-oxazolidin-2-ones
JP2669579B2 (ja) * 1991-10-23 1997-10-29 エーザイ株式会社 オキサゾリドン誘導体
DE4332384A1 (de) * 1993-09-23 1995-03-30 Merck Patent Gmbh Adhäsionsrezeptor-Antagonisten III
TW286317B (no) * 1993-12-13 1996-09-21 Hoffmann La Roche
DE4425613A1 (de) * 1994-07-20 1996-01-25 Bayer Ag 5-gliedrige Heteroaryl-oxazolidinone

Also Published As

Publication number Publication date
CZ12997A3 (en) 1997-08-13
CO4520187A1 (es) 1997-10-15
MX9700421A (es) 1997-07-31
ZA97303B (en) 1997-07-17
BR9700702A (pt) 1998-09-01
AU1009897A (en) 1997-07-24
HU9700136D0 (en) 1997-03-28
TR199601001A1 (tr) 1997-08-21
US5827857A (en) 1998-10-27
SG50002A1 (en) 1998-06-15
EE9700031A (et) 1997-08-15
BG101132A (en) 1998-04-30
SK5997A3 (en) 1997-09-10
JPH09194482A (ja) 1997-07-29
HRP960615A2 (en) 1998-02-28
IL119995A0 (en) 1997-04-15
PL317929A1 (en) 1997-07-21
EP0785200A2 (de) 1997-07-23
NO970175D0 (no) 1997-01-15
EP0785200A3 (de) 1999-02-10
TNSN97008A1 (fr) 2005-03-15
SV1997000003A (es) 1997-08-19
CA2194938A1 (en) 1997-07-17
DE19601264A1 (de) 1997-07-17
KR970059180A (ko) 1997-08-12

Similar Documents

Publication Publication Date Title
NO970175L (no) Pyrido-annellerte tienyl- og furanyl-oksazolidinoner
NO971471L (no) Nye karboksamider med fungicid aktivitet
NO970512L (no) Nye heteroaryl-oksazolidinoner
ATE122349T1 (de) 3-piperidinyl-1,2-benzisoxazole.
DK117087A (da) Heterocycliske forbindelser, deres fremstilling oganvendelse som insekticider
AU537414B2 (en) Pyroglutamic acid derivatives
ES2179071T3 (es) Agentes vasodilatadores perifericos que comprenden como principio activo derivados de la piperidina 4-amino n-acilada.
HUT55605A (en) Herbicide compositions containing diamino-triazine derivatives as active componentsand process for producing the active components
NO983955L (no) Nye erytromycinderivater, metode for fremstilling av disse og anvendelse derav som legemidler
DK0923554T3 (da) N-Benzylpiperidin- og tetrahydropyridinderivater
DE69615802D1 (de) Heterocyclische substituierte Benzofuran-Harnstoffe
DE69231422D1 (de) Pyridoncarbonsäurederivate
ES2055867T3 (es) Derivados de dibenzotiazepina utiles como agentes antiespasmodicos.
NO961236L (no) Pyrrolodiazin-derivater som stabilisatorer for klorholdige polymerisater
ATE35812T1 (de) Gamma-butyrolactonderivate, verfahren zur herstellung derselben und dieselben als aktive bestandteile enthaltende immunomodulierende zubereitungen.
ES2129123T3 (es) Nuevo derivado de bisoxadiazolidina.
EP0974598A3 (fr) Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments
ZA984114B (en) Substituted heterocyclic compounds a process for the preparation thereof and pharmaceutical compositions containing them
NO933170L (no) Heterocykliske forbindelser
ATE179170T1 (de) 3-substituierte pyridinverbindungen und deren derivate als herbizide
ATE285240T1 (de) Verwendung von sulfoquinovosyldiacylglycerol derivativen als immunosuppresssiva
NO984547L (no) Nye oksazolidinderivater, fremgangsmÕte for deres fremstilling, samt legemidler inneholdende disse forbindelser
NO992316L (no) Benzensulfonamidderivater og legemidler inneholdende disse
ATE47592T1 (de) Piperidinderivate und diese enthaltende fungizide sowie verfahren zur bekaempfung von pilzen.
ATE122352T1 (de) 3-(3-ethyl-1,2,4-oxadiazol-5-yl)-1- azabicycloheptan, verfahren zu seiner herstellung und dieses enthaltende pharmazeutische zubereitungen.