ES2055867T3 - Derivados de dibenzotiazepina utiles como agentes antiespasmodicos. - Google Patents

Derivados de dibenzotiazepina utiles como agentes antiespasmodicos.

Info

Publication number
ES2055867T3
ES2055867T3 ES90305718T ES90305718T ES2055867T3 ES 2055867 T3 ES2055867 T3 ES 2055867T3 ES 90305718 T ES90305718 T ES 90305718T ES 90305718 T ES90305718 T ES 90305718T ES 2055867 T3 ES2055867 T3 ES 2055867T3
Authority
ES
Spain
Prior art keywords
dibenzotiazepine
antiespasmodic
agents
derivatives useful
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90305718T
Other languages
English (en)
Inventor
David Dr Alker
Robert J Dr Bass
Peter Edward Dr Cross
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of ES2055867T3 publication Critical patent/ES2055867T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)

Abstract

LA INVENCION PROVEE COMPUESTO DE FORMULA I DONDE D ES 1,2, O 3; M ES 1,2, O 3; N ES 1,2, O 3; P ES 0,1, O 2; X ES O, S O UN ENLACE DIRECTO CON LA PREVISION DE QUE CUANDO X ES O O S, N ES 2 O 3; R1 ES H O ALQUIL C1-C4; Y R2 ES UN GRUPO HETEROARILICO A FENILICO SUSTITUIDO; Y SALES FARMACEUTICAMENTE ACEPTABLES DEL MISMO. ESTOS DERIVADOS SON UTILES COMO AGENTES ANTIPASMOCLICOS.
ES90305718T 1989-05-27 1990-05-25 Derivados de dibenzotiazepina utiles como agentes antiespasmodicos. Expired - Lifetime ES2055867T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898912303A GB8912303D0 (en) 1989-05-27 1989-05-27 Therapeutic agents

Publications (1)

Publication Number Publication Date
ES2055867T3 true ES2055867T3 (es) 1994-09-01

Family

ID=10657526

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90305718T Expired - Lifetime ES2055867T3 (es) 1989-05-27 1990-05-25 Derivados de dibenzotiazepina utiles como agentes antiespasmodicos.

Country Status (20)

Country Link
US (1) US5071844A (es)
EP (1) EP0404359B1 (es)
JP (1) JPH0317079A (es)
KR (1) KR900018091A (es)
CN (1) CN1047673A (es)
AT (1) ATE107927T1 (es)
AU (1) AU5595490A (es)
CA (1) CA2017535C (es)
DD (1) DD294718A5 (es)
DE (1) DE69010285T2 (es)
DK (1) DK0404359T3 (es)
ES (1) ES2055867T3 (es)
FI (1) FI96950C (es)
GB (1) GB8912303D0 (es)
HU (1) HUT58329A (es)
IE (1) IE64196B1 (es)
IL (1) IL94457A0 (es)
NO (1) NO902336L (es)
PL (1) PL285350A1 (es)
PT (1) PT94151B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5057513A (en) * 1989-05-25 1991-10-15 Fujisawa Pharmaceutical Co., Ltd. Spiro-thiazepine derivatives useful as paf antagonists
IT1247509B (it) * 1991-04-19 1994-12-17 Univ Cagliari Composti di sintesi atti all'impiego nella terapia delle infezioni da rhinovirus
US5437291A (en) * 1993-08-26 1995-08-01 Univ Johns Hopkins Method for treating gastrointestinal muscle disorders and other smooth muscle dysfunction
ZA972038B (en) * 1996-03-11 1997-09-17 Ajinomoto Kk 5, 11-dihydrobenzo[b,e][1,4]oxazepine derivatives and pharmaceutical composition containing the same.
ATE232861T1 (de) 1997-09-10 2003-03-15 Ajinomoto Kk 5,11-dihydrobenz(b,e)(1,4)oxazepin-derivate und diese enthaltende medizinische zubereitungen
EP0915088B1 (en) * 1997-10-31 2002-09-18 F. Hoffmann-La Roche Ag D-Proline derivatives
US6541479B1 (en) 1997-12-02 2003-04-01 Massachusetts College Of Pharmacy Calcium channel blockers
JP2002516904A (ja) 1998-06-03 2002-06-11 ジーピーアイ ニル ホールディングス インコーポレイテッド Ｎ−複素環式カルボン酸またはカルボン酸等配電子体のｎ−結合スルホンアミド
EP1475373A1 (en) * 1999-01-08 2004-11-10 Ajinomoto Co., Inc. 5,11-Dihydrodibenzo[b,e][1,4]-oxazepine derivatives as calcium channel antagonists
AU6868900A (en) * 1999-09-03 2001-04-10 Ajinomoto Co., Inc. Novel processes for preparing oxazepine derivatives
JPWO2002096891A1 (ja) 2001-05-30 2004-09-09 味の素株式会社 ジヒドロジアリールオキサゼピン誘導体及び該誘導体を含有する医薬組成物
JP2005343791A (ja) * 2002-05-31 2005-12-15 Ajinomoto Co Inc 消化管疾患を治療するための医薬組成物
JP2005343790A (ja) * 2002-05-31 2005-12-15 Ajinomoto Co Inc カルシウムチャネル拮抗薬を含有する医薬組成物
UY32826A (es) 2009-08-04 2011-02-28 Takeda Pharmaceutical Compuestos heterocíclicos

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB988008A (es) * 1900-01-01
GB774882A (en) * 1954-06-21 1957-05-15 Rhone Poulenc Sa Improvements in or relating to phenthiazine derivatives
GB975705A (en) * 1960-04-14 1964-11-18 Westminster Bank Ltd Improvements in or relating to the preparation of 3-alkylmercapto phenothiazines and intermediates formed in the process
CH407127A (de) * 1962-02-19 1966-02-15 Geigy Ag J R Verfahren zur Herstellung von N-heterocyclischen Verbindungen
US3188322A (en) * 1962-08-08 1965-06-08 Olin Mathieson Dihydrodibenzothiazepines

Also Published As

Publication number Publication date
GB8912303D0 (en) 1989-07-12
CA2017535A1 (en) 1990-11-27
DK0404359T3 (da) 1994-07-25
CA2017535C (en) 2000-02-29
IE64196B1 (en) 1995-07-12
HU903197D0 (en) 1990-10-28
IE901883L (en) 1990-11-27
NO902336D0 (no) 1990-05-25
FI902632A0 (fi) 1990-05-25
EP0404359A1 (en) 1990-12-27
PL285350A1 (en) 1991-05-20
PT94151A (pt) 1991-01-08
CN1047673A (zh) 1990-12-12
JPH057389B2 (es) 1993-01-28
AU5595490A (en) 1990-11-29
HUT58329A (en) 1992-02-28
DD294718A5 (de) 1991-10-10
US5071844A (en) 1991-12-10
PT94151B (pt) 1996-12-31
NO902336L (no) 1990-11-28
FI96950C (fi) 1996-09-25
EP0404359B1 (en) 1994-06-29
KR900018091A (ko) 1990-12-20
DE69010285D1 (de) 1994-08-04
JPH0317079A (ja) 1991-01-25
FI96950B (fi) 1996-06-14
ATE107927T1 (de) 1994-07-15
IL94457A0 (en) 1991-06-10
DE69010285T2 (de) 1994-10-13

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