NO961000L - Piperidinderivater, fremgangsmåte for fremstilling derav og medikament og preparat inneholdende slike - Google Patents

Piperidinderivater, fremgangsmåte for fremstilling derav og medikament og preparat inneholdende slike

Info

Publication number
NO961000L
NO961000L NO961000A NO961000A NO961000L NO 961000 L NO961000 L NO 961000L NO 961000 A NO961000 A NO 961000A NO 961000 A NO961000 A NO 961000A NO 961000 L NO961000 L NO 961000L
Authority
NO
Norway
Prior art keywords
preparation
piperidine derivatives
drug
preparation containing
methyl
Prior art date
Application number
NO961000A
Other languages
English (en)
Other versions
NO961000D0 (no
Inventor
Luc Even
Samir Jegham
Gerard Defosse
Michel Aletru
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of NO961000D0 publication Critical patent/NO961000D0/no
Publication of NO961000L publication Critical patent/NO961000L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Piperidinderivater med den generelle formel (I) (D hvor X representerer et oksygenatom eller en metylengruppe, R, representerer et klor- eller fluoratom eller en metyl, metoksy eller aminogruppe, og R2 og R3 representerer, uavhengig av hverandre, hydrogenatomer eller metylgrupper. Derivatene har terapeutisk anvendelse.
NO961000A 1995-03-13 1996-03-12 Piperidinderivater, fremgangsmåte for fremstilling derav og medikament og preparat inneholdende slike NO961000L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9502863A FR2731708B1 (fr) 1995-03-13 1995-03-13 Derives de piperidine, leur procede de preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
NO961000D0 NO961000D0 (no) 1996-03-12
NO961000L true NO961000L (no) 1996-09-16

Family

ID=9476960

Family Applications (1)

Application Number Title Priority Date Filing Date
NO961000A NO961000L (no) 1995-03-13 1996-03-12 Piperidinderivater, fremgangsmåte for fremstilling derav og medikament og preparat inneholdende slike

Country Status (15)

Country Link
EP (1) EP0732334A1 (no)
JP (1) JPH08269058A (no)
KR (1) KR960034205A (no)
CN (1) CN1140174A (no)
AU (1) AU4800896A (no)
CA (1) CA2171579A1 (no)
CZ (1) CZ75496A3 (no)
FR (1) FR2731708B1 (no)
HU (1) HUP9600624A2 (no)
IL (1) IL117455A0 (no)
NO (1) NO961000L (no)
NZ (1) NZ286164A (no)
PL (1) PL313204A1 (no)
SK (1) SK34196A3 (no)
ZA (1) ZA961994B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2231887A1 (en) * 1995-09-18 1997-03-27 Glaxo Group Limited 5-ht3 receptor antagonists for dyskinesia
TW527186B (en) 1996-03-19 2003-04-11 Janssen Pharmaceutica Nv Fused imidazole derivatives as multidrug resistance modulators
FR2801589A1 (fr) * 1999-11-25 2001-06-01 Sanofi Synthelabo Derives de 2-arylquinoleine, leur preparation et leur application en therapeutique
AR030121A1 (es) * 2000-08-08 2003-08-13 Sanofi Aventis Derivados de benzimidazol, su preparacion y su aplicacion en terapeutica
FR2816619B1 (fr) * 2000-11-15 2003-01-31 Sanofi Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique
FR2816941B1 (fr) * 2000-11-23 2003-01-31 Sanofi Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique
FR2816942B1 (fr) 2000-11-23 2003-05-09 Sanofi Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique
EP3581576B1 (en) * 2013-03-15 2022-01-26 Incyte Holdings Corporation Tricyclic heterocycles as bet protein inhibitors for use in the treatment of a proliferative disease in combination with a janus kinase inhibitor
JP2016523964A (ja) 2013-07-08 2016-08-12 インサイト・ホールディングス・コーポレイションＩｎｃｙｔｅ Ｈｏｌｄｉｎｇｓ Ｃｏｒｐｏｒａｔｉｏｎ Ｂｅｔタンパク質阻害剤としての三環式複素環
WO2015081203A1 (en) 2013-11-26 2015-06-04 Incyte Corporation Bicyclic heterocycles as bet protein inhibitors
US9315501B2 (en) 2013-11-26 2016-04-19 Incyte Corporation Bicyclic heterocycles as BET protein inhibitors
WO2015095492A1 (en) 2013-12-19 2015-06-25 Incyte Corporation Tricyclic heterocycles as bet protein inhibitors
KR102430144B1 (ko) 2014-04-23 2022-08-08 인사이트 코포레이션 BET 단백질의 저해제로서의 1H-피롤로[2,3-c]피리딘-7(6H)-온 및 피라졸로[3,4-c]피리딘-7(6H)-온
WO2016044130A1 (en) * 2014-09-15 2016-03-24 Incyte Corporation Tricyclic heterocycles for use as bet protein inhibitors
WO2017075377A1 (en) 2015-10-29 2017-05-04 Incyte Corporation Amorphous solid form of a bet protein inhibitor
LT3472157T (lt) 2016-06-20 2023-09-11 Incyte Corporation Kristalinės kietos bet inhibitoriaus formos
WO2020006432A1 (en) * 2018-06-28 2020-01-02 Eternity Bioscience Inc. Fused tricyclic heterocycle compounds and therapeutic uses thereof
US11833155B2 (en) 2020-06-03 2023-12-05 Incyte Corporation Combination therapy for treatment of myeloproliferative neoplasms

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2674855B1 (fr) * 1991-04-03 1994-01-14 Synthelabo Derives de piperidine, leur preparation et leur application en therapeutique.
FR2696176B1 (fr) * 1992-09-28 1994-11-10 Synthelabo Dérivés de pipéridine, leur préparation et leur application en thérapeutique.
FR2710915B1 (fr) * 1993-10-04 1995-11-24 Synthelabo Dérivés de pipéridine, leur préparation et leur utilisation en thérapeutique.

Also Published As

Publication number Publication date
FR2731708B1 (fr) 1997-04-30
HU9600624D0 (en) 1996-05-28
FR2731708A1 (fr) 1996-09-20
SK34196A3 (en) 1996-10-02
PL313204A1 (en) 1996-09-16
EP0732334A1 (fr) 1996-09-18
JPH08269058A (ja) 1996-10-15
CA2171579A1 (en) 1996-09-14
IL117455A0 (en) 1996-07-23
KR960034205A (ko) 1996-10-22
AU4800896A (en) 1996-09-26
HUP9600624A2 (en) 1997-01-28
NO961000D0 (no) 1996-03-12
CZ75496A3 (en) 1996-10-16
CN1140174A (zh) 1997-01-15
NZ286164A (en) 1996-11-26
ZA961994B (en) 1996-09-03

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