SI2651965T1 - Analogne molekule ciklosporina, modificirane pri aminokislini 1 v 3 - Google Patents
Analogne molekule ciklosporina, modificirane pri aminokislini 1 v 3Info
- Publication number
- SI2651965T1 SI2651965T1 SI201131640T SI201131640T SI2651965T1 SI 2651965 T1 SI2651965 T1 SI 2651965T1 SI 201131640 T SI201131640 T SI 201131640T SI 201131640 T SI201131640 T SI 201131640T SI 2651965 T1 SI2651965 T1 SI 2651965T1
- Authority
- SI
- Slovenia
- Prior art keywords
- amino acid
- molecules modified
- analogue molecules
- cyclosporine analogue
- cyclosporine
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42357610P | 2010-12-15 | 2010-12-15 | |
EP11848865.9A EP2651965B1 (en) | 2010-12-15 | 2011-12-14 | Cyclosporine analogue molecules modified at amino acid 1 and 3 |
PCT/CA2011/050773 WO2012079172A1 (en) | 2010-12-15 | 2011-12-14 | Cyclosporine analogue molecules modified at amino acid 1 and 3 |
Publications (1)
Publication Number | Publication Date |
---|---|
SI2651965T1 true SI2651965T1 (sl) | 2019-03-29 |
Family
ID=46243924
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201131640T SI2651965T1 (sl) | 2010-12-15 | 2011-12-14 | Analogne molekule ciklosporina, modificirane pri aminokislini 1 v 3 |
Country Status (25)
Country | Link |
---|---|
US (2) | US9200038B2 (sl) |
EP (2) | EP3461835A1 (sl) |
JP (3) | JP6144627B2 (sl) |
KR (3) | KR20190002731A (sl) |
CN (2) | CN107496902B (sl) |
AU (1) | AU2011342284C1 (sl) |
BR (1) | BR112013014890B1 (sl) |
CA (1) | CA2821009C (sl) |
DK (1) | DK2651965T3 (sl) |
ES (1) | ES2705750T3 (sl) |
HK (1) | HK1243633A1 (sl) |
HR (1) | HRP20190096T1 (sl) |
HU (1) | HUE042490T2 (sl) |
IL (1) | IL226792A (sl) |
LT (1) | LT2651965T (sl) |
MX (1) | MX353720B (sl) |
MY (2) | MY165152A (sl) |
NZ (1) | NZ611620A (sl) |
PL (1) | PL2651965T3 (sl) |
PT (1) | PT2651965T (sl) |
RU (1) | RU2630690C9 (sl) |
SG (2) | SG10201510236XA (sl) |
SI (1) | SI2651965T1 (sl) |
TR (1) | TR201900128T4 (sl) |
WO (1) | WO2012079172A1 (sl) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9890198B2 (en) | 2010-12-03 | 2018-02-13 | S&T Global Inc. | Cyclosporin derivatives and uses thereof |
EP3461835A1 (en) * | 2010-12-15 | 2019-04-03 | ContraVir Pharmaceuticals, Inc. | Cyclosporine analogue molecules modified at amino acid 1 and 3 |
EP2855508B1 (en) | 2012-06-01 | 2018-02-14 | Allergan, Inc. | Cyclosporin a analogs |
WO2014132084A1 (en) * | 2013-03-01 | 2014-09-04 | Ucl Business Plc | Non-immunosuppressive cyclosporin derivatives as antiviral agents |
AU2014311346A1 (en) * | 2013-08-26 | 2016-03-17 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues for preventing or treating hepatitis C |
US9914755B2 (en) | 2015-01-08 | 2018-03-13 | Allergan, Inc. | Cyclosporin derivatives wherein the MeBmt sidechain has been cyclized |
US20190151403A1 (en) * | 2016-05-17 | 2019-05-23 | S&T Global Inc. | Novel cyclosporin derivatives and uses thereof |
US20180206726A1 (en) | 2016-12-07 | 2018-07-26 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
WO2018106928A1 (en) | 2016-12-08 | 2018-06-14 | Contravir Pharmaceuticals, Inc. | Treatment and prevention of hbv diseases by cyclosporine analogue molecules modified at amino acides 1 and 3 |
AU2017378406A1 (en) | 2016-12-14 | 2019-06-13 | Biora Therapeutics, Inc. | Treatment of a disease of the gastrointestinal tract with an immunosuppressant |
AR111464A1 (es) | 2017-04-14 | 2019-07-17 | Contravir Pharmaceuticals Inc | Terapia combinada para el tratamiento de infecciones virales |
EP3612540A1 (en) | 2017-04-20 | 2020-02-26 | Rising Tide Foundation | Triphenylphosphonium-tethered tetracycyclines for use in treating cancer |
US20230041197A1 (en) | 2018-06-20 | 2023-02-09 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
EP3840769A4 (en) * | 2018-08-22 | 2022-06-22 | Bacainn Biotherapeutics, Ltd. | CYCLOSPORINE COMPOSITIONS AND METHODS OF USE |
US20210269479A1 (en) * | 2020-02-25 | 2021-09-02 | Hepion Pharmaceuticals, Inc. | Use of cyclosporine analogues for treating cancer |
TW202144378A (zh) * | 2020-03-26 | 2021-12-01 | 大陸商睿諾醫療科技(上海)有限公司 | 親環蛋白抑制劑及其用途 |
KR20230116002A (ko) * | 2020-11-29 | 2023-08-03 | 헤피온 파마슈티컬스, 인크. | 항혈전제로서 시클로스포린 유사체의 용도 |
CN113173974A (zh) * | 2021-03-18 | 2021-07-27 | 北京大学深圳研究生院 | 环孢素衍生物的合成方法 |
CN115677533B (zh) * | 2021-07-30 | 2023-12-05 | 沈阳化工研究院有限公司 | 一种4-庚基苯甲腈的制备方法 |
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CH614931A5 (sl) | 1975-11-04 | 1979-12-28 | Sandoz Ag | |
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US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
DE2819094A1 (de) | 1977-05-10 | 1978-11-23 | Sandoz Ag | Cyclosporin-derivate, ihre verwendung und herstellung |
SE448386B (sv) | 1978-10-18 | 1987-02-16 | Sandoz Ag | Nya cyklosporinderivat, forfarande for framstellning av dem samt farmaceutisk komposition innehallande dem |
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EP0056782B1 (en) | 1981-01-09 | 1984-08-01 | Sandoz Ag | Novel cyclosporins |
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JPS6182786A (ja) | 1984-09-28 | 1986-04-26 | ブラザー工業株式会社 | ミシン |
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EP0484281B2 (en) | 1990-11-02 | 2000-11-22 | Novartis AG | Cyclosporins |
GB9204466D0 (en) | 1992-03-02 | 1992-04-15 | Sandoz Ltd | Improvements in or relating to organic compounds |
WO1997011092A1 (fr) | 1994-04-07 | 1997-03-27 | Nippon Shinyaku Co., Ltd. | Derives de phosphates de cyclosporine et composition medicinale |
US5639852A (en) | 1994-09-01 | 1997-06-17 | Wisconsin Alumni Research Foundation | Immunostimulatory agents |
US5948693A (en) | 1994-09-01 | 1999-09-07 | Wisconsin Alumni Research Foundation | Solid phase synthesis of immunosuppressive agents |
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