BR112013008864A2 - análogos d ciclosporina - Google Patents

análogos d ciclosporina

Info

Publication number
BR112013008864A2
BR112013008864A2 BR112013008864A BR112013008864A BR112013008864A2 BR 112013008864 A2 BR112013008864 A2 BR 112013008864A2 BR 112013008864 A BR112013008864 A BR 112013008864A BR 112013008864 A BR112013008864 A BR 112013008864A BR 112013008864 A2 BR112013008864 A2 BR 112013008864A2
Authority
BR
Brazil
Prior art keywords
cyclosporine analogs
cyclosporine
analogs
Prior art date
Application number
BR112013008864A
Other languages
English (en)
Inventor
Catherine Simone Victorire Frydrych
Christopher S Schaumburg
Michael E Garst
Michael E Stern
William Robert Carling
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of BR112013008864A2 publication Critical patent/BR112013008864A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
BR112013008864A 2010-10-12 2011-10-11 análogos d ciclosporina BR112013008864A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39244910P 2010-10-12 2010-10-12
PCT/US2011/055791 WO2012051194A1 (en) 2010-10-12 2011-10-11 Cyclosporin analogs

Publications (1)

Publication Number Publication Date
BR112013008864A2 true BR112013008864A2 (pt) 2016-06-28

Family

ID=44883784

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013008864A BR112013008864A2 (pt) 2010-10-12 2011-10-11 análogos d ciclosporina

Country Status (13)

Country Link
US (3) US20120088734A1 (pt)
EP (1) EP2627664B1 (pt)
JP (2) JP5805774B2 (pt)
KR (1) KR20140026329A (pt)
CN (1) CN103328497A (pt)
AU (1) AU2011316690C1 (pt)
BR (1) BR112013008864A2 (pt)
CA (1) CA2814192A1 (pt)
IL (1) IL225617A0 (pt)
MX (1) MX2013004061A (pt)
RU (1) RU2013119869A (pt)
SG (1) SG189880A1 (pt)
WO (1) WO2012051194A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9573978B2 (en) 2010-08-12 2017-02-21 S&T Global, Inc. Cyclosporin derivatives for the treatment and prevention of a viral infection
JP5805773B2 (ja) 2010-10-12 2015-11-10 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ シクロスポリンアナログ
WO2012051194A1 (en) * 2010-10-12 2012-04-19 Allergan, Inc. Cyclosporin analogs
US9890198B2 (en) * 2010-12-03 2018-02-13 S&T Global Inc. Cyclosporin derivatives and uses thereof
MY165152A (en) * 2010-12-15 2018-02-28 Contravir Pharmaceuticals Inc Cyclosporine analogue molecules modified at amino acid 1 and 3
EP2855508B1 (en) 2012-06-01 2018-02-14 Allergan, Inc. Cyclosporin a analogs
GB201222455D0 (en) * 2012-12-13 2013-01-30 Perioc Ltd Novel pharmaceutical formulations and their use in the treatment of periodontaldisease
EP2964268A1 (en) 2013-03-08 2016-01-13 Allergan, Inc. Antibiotic conjugates
TW201639873A (zh) 2015-01-08 2016-11-16 歐樂根公司 Ｍｅｂｍｔ側鏈已環化之環孢菌素衍生物
WO2016160362A1 (en) 2015-03-31 2016-10-06 Allergan, Inc. Cyclosporins modified on the mebmt sidechain by heterocyclic rings
CA3024320A1 (en) * 2016-05-17 2017-11-23 S&T Global Inc. Novel cyclosporin derivatives and uses thereof
US20180164221A1 (en) 2016-12-07 2018-06-14 Progenity Inc. Gastrointestinal tract detection methods, devices and systems
JP2020513280A (ja) 2016-12-14 2020-05-14 プロジェニティ， インコーポレイテッド 消化管疾病の免疫抑制剤による治療
WO2019246312A1 (en) 2018-06-20 2019-12-26 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immunomodulator
WO2021173474A1 (en) * 2020-02-26 2021-09-02 Bacainn Biotherapeutics, Ltd. Cyclosporine compositions and methods of use
CN113173974A (zh) * 2021-03-18 2021-07-27 北京大学深圳研究生院 环孢素衍生物的合成方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0194972B1 (en) 1985-03-11 1992-07-29 Sandoz Ag Novel cyclosporins
US4649047A (en) * 1985-03-19 1987-03-10 University Of Georgia Research Foundation, Inc. Ophthalmic treatment by topical administration of cyclosporin
US4839342A (en) 1987-09-03 1989-06-13 University Of Georgia Research Foundation, Inc. Method of increasing tear production by topical administration of cyclosporin
US5474979A (en) 1994-05-17 1995-12-12 Allergan, Inc. Nonirritating emulsions for sensitive tissue
FR2757521B1 (fr) * 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2757522B1 (fr) * 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2762843B1 (fr) 1997-04-30 1999-12-10 Rhone Poulenc Rorer Sa Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
PT1086124E (pt) * 1998-06-12 2004-04-30 Chem Ag C Ciclosporinas novas
US6254860B1 (en) * 1999-04-13 2001-07-03 Allergan Sales, Inc. Ocular treatment using cyclosporin-A derivatives
US20050059583A1 (en) * 2003-09-15 2005-03-17 Allergan, Inc. Methods of providing therapeutic effects using cyclosporin components
US7676680B2 (en) 2005-07-08 2010-03-09 Morgan Stanley Systems and methods for distributing private placement documents
US7288520B2 (en) 2005-07-13 2007-10-30 Allergan, Inc. Cyclosporin compositions
WO2007136759A2 (en) 2006-05-19 2007-11-29 Scynexis, Inc. Method for the treatment and prevention of ocular disorders
CN101130058B (zh) * 2006-08-23 2011-10-05 华北制药集团新药研究开发有限责任公司 一种环孢菌素a眼用乳剂及其制备方法
BRPI0811538A2 (pt) * 2007-05-04 2015-08-11 Allergan Inc Uso de ciclosporinas no tratamento de pacientes com lentes intraoculares.
BRPI0915552A2 (pt) * 2008-07-10 2017-06-20 Allergan Inc derivados de ciclosporina, seu uso e sua composição farmacêutica
BR112012031153A2 (pt) * 2010-07-02 2016-11-08 Exxonmobil Upstream Res Co sistemas e métodos de geração de energia de triplo-ciclo de baixa emissão
WO2012005494A2 (ko) 2010-07-06 2012-01-12 엘지전자 주식회사 무선 통신 시스템에서 머신형 통신 장치를 위한 무선 자원 할당 방법 및 장치
WO2012051194A1 (en) * 2010-10-12 2012-04-19 Allergan, Inc. Cyclosporin analogs
US9890198B2 (en) 2010-12-03 2018-02-13 S&T Global Inc. Cyclosporin derivatives and uses thereof
CA2819608C (en) * 2010-12-03 2020-03-31 S&T Global Inc. Novel cyclosporin derivatives for the treatment and prevention of a viral infection
WO2013028615A2 (en) * 2011-08-19 2013-02-28 S&T Golbal Inc. Novel cyclosporin derivatives for the treatment and prevention of viral infections

Also Published As

Publication number Publication date
US20120088734A1 (en) 2012-04-12
EP2627664A1 (en) 2013-08-21
JP6250608B2 (ja) 2017-12-20
MX2013004061A (es) 2013-07-22
US20150065433A1 (en) 2015-03-05
AU2011316690B2 (en) 2016-07-07
AU2011316690A1 (en) 2013-05-02
JP5805774B2 (ja) 2015-11-10
JP2013540776A (ja) 2013-11-07
JP2016029050A (ja) 2016-03-03
US10065992B2 (en) 2018-09-04
IL225617A0 (en) 2013-06-27
KR20140026329A (ko) 2014-03-05
CN103328497A (zh) 2013-09-25
CA2814192A1 (en) 2012-04-19
RU2013119869A (ru) 2014-11-20
EP2627664B1 (en) 2018-04-04
AU2011316690C1 (en) 2017-01-19
US20170029469A1 (en) 2017-02-02
WO2012051194A1 (en) 2012-04-19
SG189880A1 (en) 2013-06-28
US9493511B2 (en) 2016-11-15

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]