SI2470656T1 - Sestavek za inhibicijo ekspresije genov in njegova uporaba - Google Patents

Sestavek za inhibicijo ekspresije genov in njegova uporaba

Info

Publication number
SI2470656T1
SI2470656T1 SI201030947T SI201030947T SI2470656T1 SI 2470656 T1 SI2470656 T1 SI 2470656T1 SI 201030947 T SI201030947 T SI 201030947T SI 201030947 T SI201030947 T SI 201030947T SI 2470656 T1 SI2470656 T1 SI 2470656T1
Authority
SI
Slovenia
Prior art keywords
composition
gene expression
inhibiting gene
inhibiting
expression
Prior art date
Application number
SI201030947T
Other languages
English (en)
Inventor
Sudhir Agrawal
Ekambar Kandimalla
Millikarjuna Putta
Tao Lan
Lakshmi Bhagat
Daqing Wang
Dong Yu
Original Assignee
Idera Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idera Pharmaceuticals, Inc. filed Critical Idera Pharmaceuticals, Inc.
Publication of SI2470656T1 publication Critical patent/SI2470656T1/sl

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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N2310/00Structure or type of the nucleic acid
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    • C12N2310/11Antisense
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/15Nucleic acids forming more than 2 strands, e.g. TFOs
    • C12N2310/152Nucleic acids forming more than 2 strands, e.g. TFOs on a single-stranded target, e.g. fold-back TFOs
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/32Chemical structure of the sugar
    • C12N2310/3212'-O-R Modification
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/35Nature of the modification
    • C12N2310/351Conjugate
    • C12N2310/3519Fusion with another nucleic acid
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/50Physical structure
    • C12N2310/51Physical structure in polymeric form, e.g. multimers, concatemers

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  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SI201030947T 2009-08-27 2010-08-26 Sestavek za inhibicijo ekspresije genov in njegova uporaba SI2470656T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US27525209P 2009-08-27 2009-08-27
US24055309P 2009-09-08 2009-09-08
EP10749570.7A EP2470656B1 (en) 2009-08-27 2010-08-26 Composition for inhibiting gene expression and uses thereof
PCT/US2010/046781 WO2011031520A1 (en) 2009-08-27 2010-08-26 Composition for inhibiting gene expression and uses thereof

Publications (1)

Publication Number Publication Date
SI2470656T1 true SI2470656T1 (sl) 2015-07-31

Family

ID=43446697

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201030947T SI2470656T1 (sl) 2009-08-27 2010-08-26 Sestavek za inhibicijo ekspresije genov in njegova uporaba

Country Status (15)

Country Link
US (3) US8431544B1 (sl)
EP (3) EP2470656B1 (sl)
JP (1) JP5805088B2 (sl)
CN (2) CN102712926B (sl)
CA (1) CA2772352A1 (sl)
DK (1) DK2470656T3 (sl)
ES (2) ES2646097T3 (sl)
HK (1) HK1210223A1 (sl)
HR (1) HRP20150566T1 (sl)
HU (1) HUE026020T2 (sl)
PL (1) PL2470656T3 (sl)
PT (1) PT2470656E (sl)
SI (1) SI2470656T1 (sl)
SM (1) SMT201500140B (sl)
WO (1) WO2011031520A1 (sl)

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