US20100233270A1
(en)
|
2009-01-08 |
2010-09-16 |
Northwestern University |
Delivery of Oligonucleotide-Functionalized Nanoparticles
|
KR101141544B1
(ko)
|
2009-03-13 |
2012-05-03 |
한국과학기술원 |
에스아이알엔에이 다중 접합체 및 이의 제조방법
|
WO2011117353A1
(en)
*
|
2010-03-24 |
2011-09-29 |
Mirrx Therapeutics A/S |
Bivalent antisense oligonucleotides
|
JP6106085B2
(ja)
|
2010-08-24 |
2017-03-29 |
サーナ・セラピューティクス・インコーポレイテッドSirna Therapeutics,Inc. |
内部非核酸スペーサーを含む一本鎖RNAi剤
|
US8877722B2
(en)
*
|
2011-03-25 |
2014-11-04 |
Idera Pharmaceuticals, Inc. |
Compositions for inhibiting gene expression and uses thereof
|
AU2012308320C1
(en)
*
|
2011-09-14 |
2018-08-23 |
Translate Bio Ma, Inc. |
Multimeric oligonucleotide compounds
|
SI3301177T1
(sl)
|
2011-11-18 |
2020-07-31 |
Alnylam Pharmaceuticals, Inc. |
Sredstva RNAi, sestavki in postopki njihove uporabe za zdravljenje s transtiretinom (TTR) povezanih bolezni
|
US9796974B2
(en)
|
2011-11-18 |
2017-10-24 |
Alnylam Pharmaceuticals, Inc. |
Modified RNAi agents
|
EP2847215A1
(en)
*
|
2012-05-07 |
2015-03-18 |
Synthes GmbH |
Methods and devices for treating intervertebral disc disease
|
US9255154B2
(en)
|
2012-05-08 |
2016-02-09 |
Alderbio Holdings, Llc |
Anti-PCSK9 antibodies and use thereof
|
ITNA20120046A1
(it)
|
2012-08-02 |
2014-02-03 |
No Self S R L |
Uso di acidi nucleici di sistemi biologici parassiti, patogeni e infestanti per l'inibizione e/o controllo degli stessi sistemi
|
WO2014022739A2
(en)
|
2012-08-03 |
2014-02-06 |
Alnylam Pharmaceuticals, Inc. |
Modified rnai agents
|
EP2895200B1
(en)
*
|
2012-09-14 |
2019-11-06 |
Translate Bio MA, Inc. |
Multimeric oligonucleotide compounds
|
HUE035887T2
(en)
|
2012-12-05 |
2018-05-28 |
Alnylam Pharmaceuticals Inc |
PCSK9 iRNA preparations and methods for their use
|
CN114015692A
(zh)
|
2013-03-14 |
2022-02-08 |
阿尔尼拉姆医药品有限公司 |
补体组分C5 iRNA组合物及其使用方法
|
EP2970970B1
(en)
|
2013-03-14 |
2018-12-12 |
Andes Biotechnologies Global, Inc. |
Antisense oligonucleotides for treatment of cancer stem cells
|
CN105408481B
(zh)
|
2013-05-22 |
2021-03-30 |
阿尔尼拉姆医药品有限公司 |
SERPINA1 iRNA组合物及其使用方法
|
TW202342750A
(zh)
|
2013-05-22 |
2023-11-01 |
美商阿尼拉製藥公司 |
TMPRSS6 iRNA組成物及其使用方法
|
TW201610151A
(zh)
|
2013-09-23 |
2016-03-16 |
阿尼拉製藥公司 |
治療或預防與甲狀腺素運載蛋白相關疾病之方法
|
CN105814205B
(zh)
|
2013-12-12 |
2019-11-19 |
阿尔尼拉姆医药品有限公司 |
补体成分iRNA组合物及其使用方法
|
WO2015106128A2
(en)
|
2014-01-09 |
2015-07-16 |
Alnylam Pharmaceuticals, Inc. |
MODIFIED RNAi AGENTS
|
WO2015123264A1
(en)
|
2014-02-11 |
2015-08-20 |
Alnylam Pharmaceuticals, Inc. |
Ketohexokinase (khk) irna compositions and methods of use thereof
|
WO2015175510A1
(en)
|
2014-05-12 |
2015-11-19 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for treating a serpinc1-associated disorder
|
EP3146049B1
(en)
|
2014-05-22 |
2020-02-26 |
Alnylam Pharmaceuticals, Inc. |
Angiotensinogen (agt) irna compositions and methods of use thereof
|
ES2725948T3
(es)
|
2014-06-04 |
2019-09-30 |
Exicure Inc |
Suministro multivalente de inmunomoduladores mediante ácidos nucleicos esféricos liposomales para aplicaciones profilácticas o terapéuticas
|
KR102494171B1
(ko)
|
2014-08-20 |
2023-02-02 |
알닐람 파마슈티칼스 인코포레이티드 |
변형 이중-가닥 rna 제제
|
JOP20200115A1
(ar)
|
2014-10-10 |
2017-06-16 |
Alnylam Pharmaceuticals Inc |
تركيبات وطرق لتثبيط التعبير الجيني عن hao1 (حمض أوكسيداز هيدروكسيلي 1 (أوكسيداز جليكولات))
|
JOP20200092A1
(ar)
|
2014-11-10 |
2017-06-16 |
Alnylam Pharmaceuticals Inc |
تركيبات iRNA لفيروس الكبد B (HBV) وطرق لاستخدامها
|
WO2016081444A1
(en)
|
2014-11-17 |
2016-05-26 |
Alnylam Pharmaceuticals, Inc. |
Apolipoprotein c3 (apoc3) irna compositions and methods of use thereof
|
CN107106493A
(zh)
|
2014-11-21 |
2017-08-29 |
西北大学 |
球形核酸纳米颗粒缀合物的序列特异性细胞摄取
|
JP2018504380A
(ja)
|
2014-12-18 |
2018-02-15 |
アルナイラム ファーマシューティカルズ, インコーポレイテッドAlnylam Pharmaceuticals, Inc. |
Reversir(商標)化合物
|
CN108064295A
(zh)
|
2015-01-14 |
2018-05-22 |
埃克西奎雷股份有限公司 |
具有核心基序的核酸纳米结构
|
WO2016130806A2
(en)
|
2015-02-13 |
2016-08-18 |
Alnylam Pharmaceuticals, Inc. |
Patatin-like phospholipase domain containing 3 (pnpla3) irna compositions and methods of use thereof
|
US9828601B2
(en)
|
2015-02-27 |
2017-11-28 |
Idera Pharmaceuticals, Inc. |
Compositions for inhibiting checkpoint gene expression and uses thereof
|
ES2901455T3
(es)
|
2015-04-03 |
2022-03-22 |
Univ Massachusetts |
Compuestos oligonucleotídicos para el tratamiento de preeclampsia y otros trastornos angiogénicos
|
WO2016161374A1
(en)
|
2015-04-03 |
2016-10-06 |
University Of Massachusetts |
Oligonucleotide compounds for targeting huntingtin mrna
|
US20160319278A1
(en)
|
2015-04-03 |
2016-11-03 |
University Of Massachusetts |
Fully stabilized asymmetric sirna
|
WO2016201301A1
(en)
|
2015-06-12 |
2016-12-15 |
Alnylam Pharmaceuticals, Inc. |
Complement component c5 irna compositions and methods of use thereof
|
CN108026527B
(zh)
|
2015-06-15 |
2022-05-10 |
Mpeg La有限责任公司 |
确定的多偶联寡核苷酸
|
DE102015008536A1
(de)
*
|
2015-07-02 |
2017-01-05 |
Rheinische Friedrich-Wilhelms-Universität Bonn |
Diskontinuierliche Oligonukleotid-Liganden
|
US20170009230A1
(en)
*
|
2015-07-08 |
2017-01-12 |
Idera Pharmaceuticals, Inc. |
Compositions for inhibiting dux4 gene expression and uses thereof
|
US10494632B2
(en)
|
2015-07-10 |
2019-12-03 |
Alnylam Pharmaceuticals, Inc. |
Insulin-like growth factor binding protein, acid labile subunit (IGFALS) compositions and methods of use thereof
|
WO2017030973A1
(en)
|
2015-08-14 |
2017-02-23 |
University Of Massachusetts |
Bioactive conjugates for oligonucleotide delivery
|
WO2017040078A1
(en)
|
2015-09-02 |
2017-03-09 |
Alnylam Pharmaceuticals, Inc. |
PROGRAMMED CELL DEATH 1 LIGAND 1 (PD-L1) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
|
SK500652015A3
(sk)
|
2015-10-15 |
2017-05-03 |
Ústav Polymérov Sav |
Spôsob úpravy funkčného stavu ľubovoľnej mRNA umožňujúci jej selektívne a špecifické rozpoznanie
|
WO2017079352A2
(en)
*
|
2015-11-04 |
2017-05-11 |
Idera Pharmaceuticals, Inc. |
Compositions for inhibiting nlrp3 gene expression and uses thereof
|
EP3408391A4
(en)
|
2016-01-31 |
2019-08-28 |
University of Massachusetts |
BRANCHED OLIGONUCLEOTIDES
|
AU2017261360A1
(en)
|
2016-05-06 |
2018-11-29 |
Exicure Operating Company |
Liposomal Spherical Nucleic Acid (SNA) constructs presenting Antisense Oligonucleotides (ASO) for specific knockdown of interleukin 17 receptor MRNA
|
WO2017205384A1
(en)
*
|
2016-05-23 |
2017-11-30 |
Idera Pharmaceuticals, Inc. |
Compositions and methods for inhibiting target rna expression
|
US20190256845A1
(en)
|
2016-06-10 |
2019-08-22 |
Alnylam Pharmaceuticals, Inc. |
COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH)
|
WO2018031933A2
(en)
|
2016-08-12 |
2018-02-15 |
University Of Massachusetts |
Conjugated oligonucleotides
|
WO2018039629A2
(en)
|
2016-08-25 |
2018-03-01 |
Northwestern University |
Micellar spherical nucleic acids from thermoresponsive, traceless templates
|
TWI788312B
(zh)
|
2016-11-23 |
2023-01-01 |
美商阿尼拉製藥公司 |
絲胺酸蛋白酶抑制因子A1 iRNA組成物及其使用方法
|
KR20230166146A
(ko)
|
2016-12-16 |
2023-12-06 |
알닐람 파마슈티칼스 인코포레이티드 |
트랜스티레틴(TTR) iRNA 조성물을 사용하여 TTR-관련 질병을 치료하거나 예방하는 방법
|
WO2018201090A1
(en)
|
2017-04-28 |
2018-11-01 |
Exicure, Inc. |
Synthesis of spherical nucleic acids using lipophilic moieties
|
US11433131B2
(en)
|
2017-05-11 |
2022-09-06 |
Northwestern University |
Adoptive cell therapy using spherical nucleic acids (SNAs)
|
CA3069868A1
(en)
|
2017-07-13 |
2019-01-17 |
Alnylam Pharmaceuticals Inc. |
Lactate dehydrogenase a (ldha) irna compositions and methods of use thereof
|
WO2019099610A1
(en)
|
2017-11-16 |
2019-05-23 |
Alnylam Pharmaceuticals, Inc. |
Kisspeptin 1 (kiss1) irna compositions and methods of use thereof
|
WO2019100039A1
(en)
|
2017-11-20 |
2019-05-23 |
Alnylam Pharmaceuticals, Inc. |
Serum amyloid p component (apcs) irna compositions and methods of use thereof
|
KR20200110655A
(ko)
|
2017-12-18 |
2020-09-24 |
알닐람 파마슈티칼스 인코포레이티드 |
고이동성 그룹 박스-1 (hmgb1) irna 조성물 및 이의 사용 방법
|
MX2020011570A
(es)
|
2018-05-07 |
2020-11-24 |
Alnylam Pharmaceuticals Inc |
Administracion extrahepatica.
|
TW202016304A
(zh)
|
2018-05-14 |
2020-05-01 |
美商阿尼拉製藥公司 |
血管收縮素原(AGT)iRNA組成物及其使用方法
|
AU2019279206A1
(en)
*
|
2018-05-31 |
2020-12-03 |
Daiichi Sankyo Company, Limited |
Anti-human TLR7 antibody
|
MX2021001590A
(es)
|
2018-08-10 |
2021-07-02 |
Univ Massachusetts |
Oligonucleótidos modificados dirigidos a snp.
|
CN112424355A
(zh)
|
2018-09-18 |
2021-02-26 |
阿尔尼拉姆医药品有限公司 |
己酮糖激酶(KHK)iRNA组合物及其使用方法
|
TW202028465A
(zh)
|
2018-09-28 |
2020-08-01 |
美商阿尼拉製藥公司 |
甲狀腺素運載蛋白(TTR)iRNA組成物及其治療或預防TTR相關眼部疾病之使用方法
|
WO2020190768A1
(en)
*
|
2019-03-15 |
2020-09-24 |
University Of Massachusetts |
Oligonucleotides for tissue specific apoe modulation
|
CN114072501A
(zh)
|
2019-05-06 |
2022-02-18 |
马萨诸塞大学 |
抗c9orf72寡核苷酸及相关方法
|
JP2022532652A
(ja)
|
2019-05-17 |
2022-07-15 |
アルニラム ファーマスーティカルズ インコーポレイテッド |
オリゴヌクレオチドの経口送達
|
EP4007811A2
(en)
|
2019-08-01 |
2022-06-08 |
Alnylam Pharmaceuticals, Inc. |
Carboxypeptidase b2 (cpb2) irna compositions and methods of use thereof
|
WO2021022109A1
(en)
|
2019-08-01 |
2021-02-04 |
Alnylam Pharmaceuticals, Inc. |
SERPIN FAMILY F MEMBER 2 (SERPINF2) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
|
BR112022002307A2
(pt)
|
2019-08-09 |
2022-06-28 |
Univ Massachusetts |
Oligonucleotídeos quimicamente modificados que têm como alvo snps
|
EP4013870A1
(en)
|
2019-08-13 |
2022-06-22 |
Alnylam Pharmaceuticals, Inc. |
Small ribosomal protein subunit 25 (rps25) irna agent compositions and methods of use thereof
|
WO2021067747A1
(en)
|
2019-10-04 |
2021-04-08 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for silencing ugt1a1 gene expression
|
US20240141358A1
(en)
|
2019-10-18 |
2024-05-02 |
Alnylam Pharmaceuticals, Inc. |
Solute carrier family member irna compositions and methods of use thereof
|
BR112022007540A2
(pt)
|
2019-10-22 |
2022-07-12 |
Alnylam Pharmaceuticals Inc |
Composições de irna de componente complementar c3 e métodos de uso das mesmas
|
WO2021087036A1
(en)
|
2019-11-01 |
2021-05-06 |
Alnylam Pharmaceuticals, Inc. |
HUNTINGTIN (HTT) iRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF
|
EP4051796A1
(en)
|
2019-11-01 |
2022-09-07 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for silencing dnajb1-prkaca fusion gene expression
|
KR20220110749A
(ko)
|
2019-11-06 |
2022-08-09 |
알닐람 파마슈티칼스 인코포레이티드 |
간외 전달
|
EP4055165A1
(en)
|
2019-11-06 |
2022-09-14 |
Alnylam Pharmaceuticals, Inc. |
Transthyretin (ttr) irna compositions and methods of use thereof for treating or preventing ttr-associated ocular diseases
|
TW202132568A
(zh)
|
2019-11-13 |
2021-09-01 |
美商阿尼拉製藥公司 |
用於治療血管收縮素原相關病症之方法及組成物
|
US20230056569A1
(en)
|
2019-11-22 |
2023-02-23 |
Alnylam Pharmaceuticals, Inc. |
Ataxin3 (atxn3) rnai agent compositions and methods of use thereof
|
IL293824A
(en)
|
2019-12-13 |
2022-08-01 |
Alnylam Pharmaceuticals Inc |
Compositions of RNA material (c9orf72) human chromosome 9 open reading frame 72 and methods of using them
|
TW202138559A
(zh)
|
2019-12-16 |
2021-10-16 |
美商阿尼拉製藥公司 |
含類PATATIN磷脂酶結構域3(PNPLA3)iRNA組成物及其使用方法
|
WO2021154941A1
(en)
|
2020-01-31 |
2021-08-05 |
Alnylam Pharmaceuticals, Inc. |
Complement component c5 irna compositions for use in the treatment of amyotrophic lateral sclerosis (als)
|
IL295445A
(en)
|
2020-02-10 |
2022-10-01 |
Alnylam Pharmaceuticals Inc |
Preparations and methods for silencing vegf-a expression
|
WO2021167841A1
(en)
|
2020-02-18 |
2021-08-26 |
Alnylam Pharmaceuticals, Inc. |
Apolipoprotein c3 (apoc3) irna compositions and methods of use thereof
|
EP4114947A1
(en)
|
2020-03-05 |
2023-01-11 |
Alnylam Pharmaceuticals, Inc. |
Complement component c3 irna compositions and methods of use thereof for treating or preventing complement component c3-associated diseases
|
EP4114948A1
(en)
|
2020-03-06 |
2023-01-11 |
Alnylam Pharmaceuticals, Inc. |
Ketohexokinase (khk) irna compositions and methods of use thereof
|
EP4121534A1
(en)
|
2020-03-18 |
2023-01-25 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for treating subjects having a heterozygous alanine-glyoxylate aminotransferase gene (agxt) variant
|
EP4127168A1
(en)
|
2020-03-26 |
2023-02-08 |
Alnylam Pharmaceuticals, Inc. |
Coronavirus irna compositions and methods of use thereof
|
EP4127171A2
(en)
|
2020-03-30 |
2023-02-08 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for silencing dnajc15 gene expression
|
WO2021207167A1
(en)
|
2020-04-06 |
2021-10-14 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for silencing myoc expression
|
CA3179678A1
(en)
|
2020-04-07 |
2021-10-14 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for silencing scn9a expression
|
WO2021206922A1
(en)
|
2020-04-07 |
2021-10-14 |
Alnylam Pharmaceuticals, Inc. |
Transmembrane serine protease 2 (tmprss2) irna compositions and methods of use thereof
|
EP4133076A1
(en)
|
2020-04-07 |
2023-02-15 |
Alnylam Pharmaceuticals, Inc. |
Angiotensin-converting enzyme 2 (ace2) irna compositions and methods of use thereof
|
CA3181400A1
(en)
|
2020-04-27 |
2021-11-04 |
Alnylam Pharmaceuticals, Inc. |
Apolipoprotein e (apoe) irna agent compositions and methods of use thereof
|
IL297680A
(en)
|
2020-04-30 |
2022-12-01 |
Alnylam Pharmaceuticals Inc |
IRNA compounds complement factor b (cfb) and methods of using them
|
WO2021237097A1
(en)
|
2020-05-21 |
2021-11-25 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting marc1 gene expression
|
WO2021252557A1
(en)
|
2020-06-09 |
2021-12-16 |
Alnylam Pharmaceuticals, Inc. |
Rnai compositions and methods of use thereof for delivery by inhalation
|
TW202214856A
(zh)
|
2020-06-18 |
2022-04-16 |
美商阿尼拉製藥公司 |
黃嘌呤脫氫酶(XDH)iRNA組成物及其使用之方法
|
US20230257745A1
(en)
|
2020-07-10 |
2023-08-17 |
Alnylam Pharmaceuticals, Inc. |
Circular siRNAs
|
EP4217489A1
(en)
|
2020-09-24 |
2023-08-02 |
Alnylam Pharmaceuticals, Inc. |
Dipeptidyl peptidase 4 (dpp4) irna compositions and methods of use thereof
|
JP2023544413A
(ja)
|
2020-10-05 |
2023-10-23 |
アルナイラム ファーマシューティカルズ, インコーポレイテッド |
Gタンパク質共役受容体75(GPR75)iRNA組成物およびその使用方法
|
EP4232581A1
(en)
|
2020-10-21 |
2023-08-30 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for treating primary hyperoxaluria
|
EP4232582A1
(en)
|
2020-10-23 |
2023-08-30 |
Alnylam Pharmaceuticals, Inc. |
Mucin 5b (muc5b) irna compositions and methods of use thereof
|
JP2023549500A
(ja)
|
2020-11-13 |
2023-11-27 |
アルナイラム ファーマシューティカルズ, インコーポレイテッド |
凝固第V因子(F5)iRNA組成物およびその使用方法
|
AU2021393417A1
(en)
|
2020-12-01 |
2023-06-29 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for inhibition of hao1 (hydroxyacid oxidase 1 (glycolate oxidase)) gene expression
|
EP4259795A1
(en)
|
2020-12-08 |
2023-10-18 |
Alnylam Pharmaceuticals, Inc. |
Coagulation factor x (f10) irna compositions and methods of use thereof
|
EP4271695A2
(en)
|
2020-12-31 |
2023-11-08 |
Alnylam Pharmaceuticals, Inc. |
2'-modified nucleoside based oligonucleotide prodrugs
|
EP4271696A2
(en)
|
2020-12-31 |
2023-11-08 |
Alnylam Pharmaceuticals, Inc. |
Cyclic-disulfide modified phosphate based oligonucleotide prodrugs
|
WO2022150260A1
(en)
|
2021-01-05 |
2022-07-14 |
Alnylam Pharmaceuticals, Inc. |
COMPLEMENT COMPONENT 9 (C9) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
|
BR112023015761A2
(pt)
|
2021-02-12 |
2023-11-07 |
Alnylam Pharmaceuticals Inc |
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|
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|
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