US20100233270A1
(en)
|
2009-01-08 |
2010-09-16 |
Northwestern University |
Delivery of Oligonucleotide-Functionalized Nanoparticles
|
KR101141544B1
(ko)
|
2009-03-13 |
2012-05-03 |
한국과학기술원 |
에스아이알엔에이 다중 접합체 및 이의 제조방법
|
WO2011117353A1
(en)
*
|
2010-03-24 |
2011-09-29 |
Mirrx Therapeutics A/S |
Bivalent antisense oligonucleotides
|
EP2609198B8
(en)
*
|
2010-08-24 |
2018-03-28 |
Sirna Therapeutics, Inc. |
SINGLE-STRANDED RNAi AGENTS CONTAINING AN INTERNAL, NON-NUCLEIC ACID SPACER
|
US8877722B2
(en)
*
|
2011-03-25 |
2014-11-04 |
Idera Pharmaceuticals, Inc. |
Compositions for inhibiting gene expression and uses thereof
|
CA2848753C
(en)
|
2011-09-14 |
2022-07-26 |
Rana Therapeutics, Inc. |
Multimeric oligonucleotide compounds
|
IN2014CN03465A
(it)
|
2011-11-18 |
2015-10-09 |
Alnylam Pharmaceuticals Inc |
|
IL308752A
(en)
|
2011-11-18 |
2024-01-01 |
Alnylam Pharmaceuticals Inc |
RNAI factors, compositions and methods of using them for the treatment of transthyretin-related diseases
|
WO2013169382A1
(en)
*
|
2012-05-07 |
2013-11-14 |
DePuy Synthes Products, LLC |
Methods and devices for treating intervertebral disc disease
|
US9255154B2
(en)
|
2012-05-08 |
2016-02-09 |
Alderbio Holdings, Llc |
Anti-PCSK9 antibodies and use thereof
|
ITNA20120046A1
(it)
|
2012-08-02 |
2014-02-03 |
No Self S R L |
Uso di acidi nucleici di sistemi biologici parassiti, patogeni e infestanti per l'inibizione e/o controllo degli stessi sistemi
|
US9708607B2
(en)
|
2012-08-03 |
2017-07-18 |
Alnylam Pharmaceuticals, Inc. |
Modified RNAi agents
|
US20150247141A1
(en)
*
|
2012-09-14 |
2015-09-03 |
Rana Therapeutics, Inc. |
Multimeric oligonucleotide compounds
|
WO2014089313A1
(en)
|
2012-12-05 |
2014-06-12 |
Alnylam Pharmaceuticals |
PCSK9 iRNA COMPOSITIONS AND METHODS OF USE THEREOF
|
DK2970974T3
(en)
|
2013-03-14 |
2017-12-04 |
Alnylam Pharmaceuticals Inc |
COMPLEMENTARY COMPONENT C5 IRNA COMPOSITIONS AND PROCEDURES FOR USE THEREOF
|
HUE042738T2
(hu)
|
2013-03-14 |
2019-07-29 |
Andes Biotechnologies Global Inc |
Antiszensz oligonukleotidok rákos õssejtek kezelésére
|
IL293657B1
(en)
|
2013-05-22 |
2024-08-01 |
Alnylam Pharmaceuticals Inc |
Preparations of TMPRSS6 iRNA and methods of using them
|
SG10201913872XA
(en)
|
2013-05-22 |
2020-03-30 |
Alnylam Pharmaceuticals Inc |
SERPINA1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF
|
AR097738A1
(es)
|
2013-09-23 |
2016-04-13 |
Alnylam Pharmaceuticals Inc |
Métodos para tratar o prevenir enfermedades asociadas con la transtiretina (ttr)
|
IL294470B1
(en)
|
2013-12-12 |
2024-08-01 |
Alnylam Pharmaceuticals Inc |
Complementary component iRNA compositions and methods for using them
|
WO2015106128A2
(en)
|
2014-01-09 |
2015-07-16 |
Alnylam Pharmaceuticals, Inc. |
MODIFIED RNAi AGENTS
|
EP3105331B1
(en)
|
2014-02-11 |
2021-06-23 |
Alnylam Pharmaceuticals, Inc. |
Ketohexokinase (khk) irna compositions and methods of use thereof
|
WO2015175510A1
(en)
|
2014-05-12 |
2015-11-19 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for treating a serpinc1-associated disorder
|
CN112301031A
(zh)
|
2014-05-22 |
2021-02-02 |
阿尔尼拉姆医药品有限公司 |
血管紧张素原(AGT)iRNA组合物及其使用方法
|
PL3164113T3
(pl)
|
2014-06-04 |
2019-09-30 |
Exicure, Inc. |
Wielowartościowe dostarczanie modulatorów immunologicznych w liposomowych kolistych kwasach nukleinowych do zastosowań profilaktycznych lub terapeutycznych
|
EP3812462A1
(en)
|
2014-08-20 |
2021-04-28 |
Alnylam Pharmaceuticals, Inc. |
Modified double-stranded rna agents
|
JOP20200115A1
(ar)
|
2014-10-10 |
2017-06-16 |
Alnylam Pharmaceuticals Inc |
تركيبات وطرق لتثبيط التعبير الجيني عن hao1 (حمض أوكسيداز هيدروكسيلي 1 (أوكسيداز جليكولات))
|
JOP20200092A1
(ar)
|
2014-11-10 |
2017-06-16 |
Alnylam Pharmaceuticals Inc |
تركيبات iRNA لفيروس الكبد B (HBV) وطرق لاستخدامها
|
CN107250362B
(zh)
|
2014-11-17 |
2021-10-22 |
阿尔尼拉姆医药品有限公司 |
载脂蛋白C3(APOC3)iRNA组合物及其使用方法
|
CA2968531A1
(en)
|
2014-11-21 |
2016-05-26 |
Northwestern University |
The sequence-specific cellular uptake of spherical nucleic acid nanoparticle conjugates
|
US20170369872A1
(en)
|
2014-12-18 |
2017-12-28 |
Alnylam Pharmaceuticals, Inc. |
Reversir tm compounds
|
US10704043B2
(en)
|
2015-01-14 |
2020-07-07 |
Exicure, Inc. |
Nucleic acid nanostructures with core motifs
|
JP2018510621A
(ja)
|
2015-02-13 |
2018-04-19 |
アルナイラム ファーマシューティカルズ, インコーポレイテッドAlnylam Pharmaceuticals, Inc. |
パタチン様ホスホリパーゼドメイン含有3(PNPLA3)iRNA組成物およびその使用方法
|
WO2016138278A2
(en)
|
2015-02-27 |
2016-09-01 |
Idera Pharmaceuticals, Inc. |
Compositions for inhibiting checkpoint gene expression and uses thereof
|
JP6892433B2
(ja)
|
2015-04-03 |
2021-06-23 |
ユニバーシティ・オブ・マサチューセッツUniversity Of Massachusetts |
十分に安定化された非対称sirna
|
ES2808750T3
(es)
|
2015-04-03 |
2021-03-01 |
Univ Massachusetts |
Compuestos oligonucleotídicos dirigidos a ARNm de huntingtina
|
ES2901455T3
(es)
|
2015-04-03 |
2022-03-22 |
Univ Massachusetts |
Compuestos oligonucleotídicos para el tratamiento de preeclampsia y otros trastornos angiogénicos
|
EP4365291A3
(en)
|
2015-06-12 |
2024-08-14 |
Alnylam Pharmaceuticals, Inc. |
Complement component c5 irna compositions and methods of use thereof
|
KR20180039621A
(ko)
|
2015-06-15 |
2018-04-18 |
엠펙 엘에이, 엘엘씨 |
정의된 다중 접합체 올리고뉴클레오티드
|
DE102015008536A1
(de)
*
|
2015-07-02 |
2017-01-05 |
Rheinische Friedrich-Wilhelms-Universität Bonn |
Diskontinuierliche Oligonukleotid-Liganden
|
US20170009230A1
(en)
*
|
2015-07-08 |
2017-01-12 |
Idera Pharmaceuticals, Inc. |
Compositions for inhibiting dux4 gene expression and uses thereof
|
WO2017011286A1
(en)
|
2015-07-10 |
2017-01-19 |
Alnylam Pharmaceuticals, Inc. |
Insulin-like growth factor binding protein, acid labile subunit (igfals) and insulin-like growth factor 1 (igf-1) irna compositions and methods of use thereof
|
CA2995110A1
(en)
|
2015-08-14 |
2017-02-23 |
University Of Massachusetts |
Bioactive conjugates for oligonucleotide delivery
|
CN114525280A
(zh)
|
2015-09-02 |
2022-05-24 |
阿尔尼拉姆医药品有限公司 |
程序性细胞死亡1配体1(PD-L1)的iRNA组合物及其使用方法
|
SK500652015A3
(sk)
|
2015-10-15 |
2017-05-03 |
Ústav Polymérov Sav |
Spôsob úpravy funkčného stavu ľubovoľnej mRNA umožňujúci jej selektívne a špecifické rozpoznanie
|
EP3371328A2
(en)
*
|
2015-11-04 |
2018-09-12 |
Idera Pharmaceuticals, Inc. |
Compositions for inhibiting nlrp3 gene expression and uses thereof
|
EP4424828A1
(en)
|
2015-12-07 |
2024-09-04 |
Genzyme Corporation |
Methods and compositions for treating a serpinc1-associated disorder
|
AU2017210726B2
(en)
|
2016-01-31 |
2023-08-03 |
University Of Massachusetts |
Branched oligonucleotides
|
CN109415731A
(zh)
|
2016-05-06 |
2019-03-01 |
埃克西奎雷股份有限公司 |
呈递用于特异性敲低白介素17受体mRNA的反义寡核苷酸(ASO)的脂质体球形核酸(SNA)构建体
|
WO2017205384A1
(en)
*
|
2016-05-23 |
2017-11-30 |
Idera Pharmaceuticals, Inc. |
Compositions and methods for inhibiting target rna expression
|
US20190256845A1
(en)
|
2016-06-10 |
2019-08-22 |
Alnylam Pharmaceuticals, Inc. |
COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH)
|
US11753638B2
(en)
|
2016-08-12 |
2023-09-12 |
University Of Massachusetts |
Conjugated oligonucleotides
|
US11364304B2
(en)
|
2016-08-25 |
2022-06-21 |
Northwestern University |
Crosslinked micellar spherical nucleic acids
|
TW202313978A
(zh)
|
2016-11-23 |
2023-04-01 |
美商阿尼拉製藥公司 |
絲胺酸蛋白酶抑制因子A1 iRNA組成物及其使用方法
|
TWI790217B
(zh)
|
2016-12-16 |
2023-01-21 |
美商阿尼拉製藥公司 |
使用甲狀腺素運載蛋白(TTR)iRNA組成物於治療或預防TTR相關疾病之方法
|
WO2018201090A1
(en)
|
2017-04-28 |
2018-11-01 |
Exicure, Inc. |
Synthesis of spherical nucleic acids using lipophilic moieties
|
US11433131B2
(en)
|
2017-05-11 |
2022-09-06 |
Northwestern University |
Adoptive cell therapy using spherical nucleic acids (SNAs)
|
JP7406793B2
(ja)
|
2017-06-23 |
2023-12-28 |
ユニバーシティー オブ マサチューセッツ |
2テイル自己デリバリー型siRNAおよび関連方法
|
AU2018301477A1
(en)
|
2017-07-13 |
2020-02-27 |
Alnylam Pharmaceuticals Inc. |
Lactate dehydrogenase a (LDHA) iRNA compositions and methods of use thereof
|
WO2019099610A1
(en)
|
2017-11-16 |
2019-05-23 |
Alnylam Pharmaceuticals, Inc. |
Kisspeptin 1 (kiss1) irna compositions and methods of use thereof
|
EP3714054A1
(en)
|
2017-11-20 |
2020-09-30 |
Alnylam Pharmaceuticals, Inc. |
Serum amyloid p component (apcs) irna compositions and methods of use thereof
|
WO2019126097A1
(en)
|
2017-12-18 |
2019-06-27 |
Alnylam Pharmaceuticals, Inc. |
High mobility group box-1 (hmgb1) irna compositions and methods of use thereof
|
WO2019217459A1
(en)
|
2018-05-07 |
2019-11-14 |
Alnylam Pharmaceuticals, Inc. |
Extrahepatic delivery
|
HUE064073T2
(hu)
|
2018-05-14 |
2024-02-28 |
Alnylam Pharmaceuticals Inc |
Angiotenzinogén (AGT) iRNS készítmények és alkalmazási eljárások
|
CA3099900A1
(en)
*
|
2018-05-31 |
2019-12-05 |
Daiichi Sankyo Company, Limited |
Anti-human tlr7 antibody
|
KR20210093227A
(ko)
|
2018-08-10 |
2021-07-27 |
유니버시티 오브 매사추세츠 |
Snp를 표적화하는 변형된 올리고뉴클레오티드
|
CN118667811A
(zh)
|
2018-09-18 |
2024-09-20 |
阿尔尼拉姆医药品有限公司 |
己酮糖激酶(KHK)iRNA组合物及其使用方法
|
JP7470107B2
(ja)
|
2018-09-28 |
2024-04-17 |
アルナイラム ファーマシューティカルズ, インコーポレイテッド |
トランスサイレチン(TTR)iRNA組成物及びTTR関連眼疾患を治療又は予防するためのその使用方法
|
AU2020239987A1
(en)
*
|
2019-03-15 |
2021-11-04 |
University Of Massachusetts |
Oligonucleotides for tissue specific ApoE modulation
|
WO2020227395A2
(en)
|
2019-05-06 |
2020-11-12 |
University Of Massachusetts |
Anti-c9orf72 oligonucleotides and related methods
|
CA3138915A1
(en)
|
2019-05-17 |
2020-11-26 |
Alnylam Pharmaceuticals, Inc. |
Oral delivery of oligonucleotides
|
EP4007812A1
(en)
|
2019-08-01 |
2022-06-08 |
Alnylam Pharmaceuticals, Inc. |
Serpin family f member 2 (serpinf2) irna compositions and methods of use thereof
|
EP4007811A2
(en)
|
2019-08-01 |
2022-06-08 |
Alnylam Pharmaceuticals, Inc. |
Carboxypeptidase b2 (cpb2) irna compositions and methods of use thereof
|
CA3149835A1
(en)
|
2019-08-09 |
2021-02-18 |
University Of Massachusetts |
Chemically modified oligonucleotides targeting snps
|
EP4013870A1
(en)
|
2019-08-13 |
2022-06-22 |
Alnylam Pharmaceuticals, Inc. |
Small ribosomal protein subunit 25 (rps25) irna agent compositions and methods of use thereof
|
EP4038189A1
(en)
|
2019-10-04 |
2022-08-10 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for silencing ugt1a1 gene expression
|
WO2021076828A1
(en)
|
2019-10-18 |
2021-04-22 |
Alnylam Pharmaceuticals, Inc. |
Solute carrier family member irna compositions and methods of use thereof
|
BR112022007540A2
(pt)
|
2019-10-22 |
2022-07-12 |
Alnylam Pharmaceuticals Inc |
Composições de irna de componente complementar c3 e métodos de uso das mesmas
|
CN114728018B
(zh)
|
2019-11-01 |
2024-07-19 |
阿尔尼拉姆医药品有限公司 |
亨廷顿(HTT)iRNA药剂组合物及其使用方法
|
WO2021087325A1
(en)
|
2019-11-01 |
2021-05-06 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for silencing dnajb1-prkaca fusion gene expression
|
CN114945669A
(zh)
|
2019-11-06 |
2022-08-26 |
阿尔尼拉姆医药品有限公司 |
肝外递送
|
EP4055165A1
(en)
|
2019-11-06 |
2022-09-14 |
Alnylam Pharmaceuticals, Inc. |
Transthyretin (ttr) irna compositions and methods of use thereof for treating or preventing ttr-associated ocular diseases
|
JP2023502038A
(ja)
|
2019-11-13 |
2023-01-20 |
アルナイラム ファーマシューティカルズ, インコーポレイテッド |
アンギオテンシノーゲン(agt)関連障害を処置するための方法および組成物
|
EP4061945A1
(en)
|
2019-11-22 |
2022-09-28 |
Alnylam Pharmaceuticals, Inc. |
Ataxin3 (atxn3) rnai agent compositions and methods of use thereof
|
MX2022006433A
(es)
|
2019-12-13 |
2022-06-23 |
Alnylam Pharmaceuticals Inc |
Composiciones de agentes de acido ribonucleico de interferencia (arni) del marco de lectura abierto 72 del cromosoma 9 humano (c9orf72) y metodos de uso de los mismos.
|
WO2021126734A1
(en)
|
2019-12-16 |
2021-06-24 |
Alnylam Pharmaceuticals, Inc. |
Patatin-like phospholipase domain containing 3 (pnpla3) irna compositions and methods of use thereof
|
CA3162845A1
(en)
|
2019-12-23 |
2021-07-01 |
Anastasia Khvorova |
Oligonucleotides for tissue specific gene expression modulation
|
WO2021154941A1
(en)
|
2020-01-31 |
2021-08-05 |
Alnylam Pharmaceuticals, Inc. |
Complement component c5 irna compositions for use in the treatment of amyotrophic lateral sclerosis (als)
|
IL295445A
(en)
|
2020-02-10 |
2022-10-01 |
Alnylam Pharmaceuticals Inc |
Preparations and methods for silencing vegf-a expression
|
KR20220143106A
(ko)
|
2020-02-18 |
2022-10-24 |
알닐람 파마슈티칼스 인코포레이티드 |
아포지질단백질 C3 (APOC3) iRNA 조성물 및 이의 사용 방법
|
EP4114947A1
(en)
|
2020-03-05 |
2023-01-11 |
Alnylam Pharmaceuticals, Inc. |
Complement component c3 irna compositions and methods of use thereof for treating or preventing complement component c3-associated diseases
|
CN115485383A
(zh)
|
2020-03-06 |
2022-12-16 |
阿尔尼拉姆医药品有限公司 |
己酮糖激酶(KHK)iRNA组合物及其使用方法
|
WO2021188611A1
(en)
|
2020-03-18 |
2021-09-23 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for treating subjects having a heterozygous alanine-glyoxylate aminotransferase gene (agxt) variant
|
CN116209759A
(zh)
|
2020-03-26 |
2023-06-02 |
阿尔尼拉姆医药品有限公司 |
冠状病毒iRNA组合物及其使用方法
|
WO2021202443A2
(en)
|
2020-03-30 |
2021-10-07 |
Alnylam Pharmaceucticals, Inc. |
Compositions and methods for silencing dnajc15 gene expression
|
AR121769A1
(es)
|
2020-04-06 |
2022-07-06 |
Alnylam Pharmaceuticals Inc |
Composiciones y métodos para el silenciamiento de la expresión de myoc
|
EP4133077A1
(en)
|
2020-04-07 |
2023-02-15 |
Alnylam Pharmaceuticals, Inc. |
Transmembrane serine protease 2 (tmprss2) irna compositions and methods of use thereof
|
BR112022020227A2
(pt)
|
2020-04-07 |
2022-11-22 |
Alnylam Pharmaceuticals Inc |
Composições e métodos para silenciamento da expressão de scn9a
|
WO2021206917A1
(en)
|
2020-04-07 |
2021-10-14 |
Alnylam Pharmaceuticals, Inc. |
ANGIOTENSIN-CONVERTING ENZYME 2 (ACE2) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
|
KR20230018377A
(ko)
|
2020-04-27 |
2023-02-07 |
알닐람 파마슈티칼스 인코포레이티드 |
아포지질단백질 e (apoe) irna 제제 조성물 및 이의 사용 방법
|
WO2021222549A1
(en)
|
2020-04-30 |
2021-11-04 |
Alnylam Pharmaceuticals, Inc. |
Complement factor b (cfb) irna compositions and methods of use thereof
|
EP4153746A1
(en)
|
2020-05-21 |
2023-03-29 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting marc1 gene expression
|
CN115698291A
(zh)
|
2020-05-28 |
2023-02-03 |
马萨诸塞大学 |
用于SARS-CoV-2调节的寡核苷酸
|
EP4162050A1
(en)
|
2020-06-09 |
2023-04-12 |
Alnylam Pharmaceuticals, Inc. |
Rnai compositions and methods of use thereof for delivery by inhalation
|
CA3184289A1
(en)
|
2020-06-18 |
2021-12-23 |
Alnylam Pharmaceuticals, Inc. |
Xanthine dehydrogenase (xdh) irna compositions and methods of use thereof
|
US20230257745A1
(en)
|
2020-07-10 |
2023-08-17 |
Alnylam Pharmaceuticals, Inc. |
Circular siRNAs
|
EP4217489A1
(en)
|
2020-09-24 |
2023-08-02 |
Alnylam Pharmaceuticals, Inc. |
Dipeptidyl peptidase 4 (dpp4) irna compositions and methods of use thereof
|
WO2022076291A1
(en)
|
2020-10-05 |
2022-04-14 |
Alnylam Pharmaceuticals, Inc. |
G protein-coupled receptor 75 (gpr75) irna compositions and methods of use thereof
|
CA3198823A1
(en)
|
2020-10-21 |
2022-04-28 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for treating primary hyperoxaluria
|
WO2022087329A1
(en)
|
2020-10-23 |
2022-04-28 |
Alnylam Pharmaceuticals, Inc. |
Mucin 5b (muc5b) irna compositions and methods of use thereof
|
EP4244355A1
(en)
|
2020-11-13 |
2023-09-20 |
Alnylam Pharmaceuticals, Inc. |
Coagulation factor v (f5) irna compositions and methods of use thereof
|
AU2021393417A1
(en)
|
2020-12-01 |
2023-06-29 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for inhibition of hao1 (hydroxyacid oxidase 1 (glycolate oxidase)) gene expression
|
WO2022125490A1
(en)
|
2020-12-08 |
2022-06-16 |
Alnylam Pharmaceuticals, Inc. |
Coagulation factor x (f10) irna compositions and methods of use thereof
|
US20240336914A1
(en)
|
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