SI20639A - Etanolat azitromicina, postopek za njegovo pripravo in njegovi farmacevtski sestavki - Google Patents

Etanolat azitromicina, postopek za njegovo pripravo in njegovi farmacevtski sestavki Download PDF

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Publication number
SI20639A
SI20639A SI9920086A SI9920086A SI20639A SI 20639 A SI20639 A SI 20639A SI 9920086 A SI9920086 A SI 9920086A SI 9920086 A SI9920086 A SI 9920086A SI 20639 A SI20639 A SI 20639A
Authority
SI
Slovenia
Prior art keywords
azithromycin
ethanolate
water
suspension
ethanol
Prior art date
Application number
SI9920086A
Other languages
English (en)
Slovenian (sl)
Inventor
Claude Singer
Judith Aronhime
Original Assignee
Teva Pharmaceutical Industries Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22332273&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI20639(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teva Pharmaceutical Industries Ltd. filed Critical Teva Pharmaceutical Industries Ltd.
Publication of SI20639A publication Critical patent/SI20639A/sl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
SI9920086A 1998-11-30 1999-11-30 Etanolat azitromicina, postopek za njegovo pripravo in njegovi farmacevtski sestavki SI20639A (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11029898P 1998-11-30 1998-11-30
PCT/US1999/028368 WO2000032203A1 (en) 1998-11-30 1999-11-30 Ethanolate of azithromycin, process for manufacture, and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
SI20639A true SI20639A (sl) 2002-02-28

Family

ID=22332273

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9920086A SI20639A (sl) 1998-11-30 1999-11-30 Etanolat azitromicina, postopek za njegovo pripravo in njegovi farmacevtski sestavki

Country Status (26)

Country Link
US (1) US6365574B2 (hu)
EP (2) EP1152765B1 (hu)
JP (1) JP2002531409A (hu)
KR (1) KR100603226B1 (hu)
CN (2) CN1273142C (hu)
AP (1) AP1709A (hu)
AT (1) ATE279200T1 (hu)
AU (1) AU768219B2 (hu)
BG (1) BG105547A (hu)
CA (1) CA2352562A1 (hu)
CZ (1) CZ20011886A3 (hu)
DE (1) DE69921192T2 (hu)
DK (1) DK1152765T3 (hu)
ES (1) ES2229804T3 (hu)
HK (1) HK1043725B (hu)
HU (1) HUP0104241A3 (hu)
IL (1) IL143376A0 (hu)
LV (1) LV12735B (hu)
NZ (1) NZ512496A (hu)
PL (1) PL197894B1 (hu)
PT (1) PT1152765E (hu)
RO (1) RO121408B1 (hu)
RU (1) RU2240124C2 (hu)
SI (1) SI20639A (hu)
WO (1) WO2000032203A1 (hu)
ZA (1) ZA200104312B (hu)

Families Citing this family (36)

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Publication number Priority date Publication date Assignee Title
HRP20020231A2 (en) * 2002-03-18 2003-12-31 Pliva D D ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A
TW546302B (en) * 1998-05-08 2003-08-11 Biochemie Sa Improvements in macrolide production
CA2245398C (en) 1998-08-21 2002-01-29 Apotex Inc. Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof
US6365574B2 (en) * 1998-11-30 2002-04-02 Teva Pharmaceutical Industries Ltd. Ethanolate of azithromycin, process for manufacture, and pharmaceutical compositions thereof
HU229488B1 (hu) * 2000-11-27 2014-01-28 Sandoz Ag Eljárás makrolid hidrátok elõállítására
CN100341886C (zh) * 2000-11-27 2007-10-10 桑多斯股份公司 大环内酯类化合物的溶剂化物
KR100431431B1 (ko) * 2001-04-25 2004-05-14 한미약품 주식회사 아지트로마이신 수화물의 1,2-프로필렌글리콜 내포화합물,그의 제조방법 및 그의 약학적 조성물
EP1671978A1 (en) * 2001-05-22 2006-06-21 Pfizer Products Inc. New Cristal Form of Azithromycin
US6861413B2 (en) 2001-05-22 2005-03-01 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
BR0209918A (pt) 2001-05-22 2004-03-30 Pfizer Prod Inc Formas cristalinas da azitromicina
HUP0402291A2 (hu) 2001-10-18 2005-03-29 Teva Pharmaceutical Industries Ltd. Stabilizált azithromycin összetételek, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
US20080149521A9 (en) * 2001-10-18 2008-06-26 Michael Pesachovich Methods of stabilizing azithromycin
EP1541134A3 (en) * 2001-10-18 2007-06-06 Teva Pharmaceutical Industries Limited Stabilized azithromycin compositions
NZ532707A (en) * 2001-12-21 2006-07-28 Pfizer Prod Inc Directly compressible formulations of azithromycin
PL371125A1 (en) * 2001-12-21 2005-06-13 Pfizer Products Inc. Methods for wet granulating azithromycin
EP1478347A1 (en) * 2002-02-01 2004-11-24 Pfizer Products Inc. Dry granulated formulations of azithromycin
HRP20020614A2 (en) * 2002-07-22 2004-06-30 PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o. Rhombic pseudopolymorph of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin a
US20050013835A1 (en) * 2003-07-15 2005-01-20 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
US20050101547A1 (en) * 2003-11-06 2005-05-12 Sadatrezaei Mohsen Stabilized azithromycin composition
US6984403B2 (en) * 2003-12-04 2006-01-10 Pfizer Inc. Azithromycin dosage forms with reduced side effects
CA2547597A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate compositions with improved stability
WO2005053639A2 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Controlled release multiparticulates formed with dissolution enhancers
WO2005053652A1 (en) 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride
BRPI0417338A (pt) * 2003-12-04 2007-04-17 Pfizer Prod Inc formas de dosagem de azitromicina multiparticulada por processos a base de lìquido
JP2007513147A (ja) * 2003-12-04 2007-05-24 ファイザー・プロダクツ・インク 押し出し機を使用して、好ましくはポロキサマーとグリセリドを含有する多粒子結晶性医薬組成物を製造するための噴霧凝結方法
SI1691787T1 (sl) * 2003-12-04 2008-10-31 Pfizer Prod Inc Postopek za pripravo farmacevtskih produktov iz več delcev
US7943585B2 (en) 2003-12-22 2011-05-17 Sandoz, Inc. Extended release antibiotic composition
US20060116336A1 (en) * 2004-03-17 2006-06-01 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation
US7468428B2 (en) * 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
US7683162B2 (en) * 2004-08-30 2010-03-23 Taro Pharmaceutical Industries Limited Process of preparing a crystalline azithromycin monohydrate
JP2008524318A (ja) * 2004-12-21 2008-07-10 ファイザー・プロダクツ・インク 安定なアジスロマイシン非二水和物の経口用懸濁液剤
US20060198895A1 (en) * 2005-03-07 2006-09-07 Kotliar Eleonora M Azithromycin powder for oral suspension compositions
WO2010103119A1 (en) 2009-03-13 2010-09-16 Da Volterra Compositions and methods for elimination of gram-negative bacteria
WO2010121187A2 (en) * 2009-04-17 2010-10-21 Micell Techologies, Inc. Stents having controlled elution
WO2013088274A1 (en) 2011-12-14 2013-06-20 Wockhardt Limited Anhydrous amorphous azithromycin composition free of azithromycin dihydrate
CN103983730B (zh) * 2014-06-11 2015-09-30 北京市药品检验所 阿奇霉素或其制剂中的杂质检查方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI8110592A8 (en) 1981-03-06 1996-06-30 Pliva Pharm & Chem Works Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
MX12213A (es) 1987-07-09 1993-05-01 Pfizer Metodo de preparacion de dihidrato de azitromicina cristalino
WO1989002271A1 (en) * 1987-09-10 1989-03-23 Pfizer Azithromycin and derivatives as antiprotozoal agents
CN1093370A (zh) * 1993-12-10 1994-10-12 北京市集才药物研究所 一种新的阿齐红霉素结晶及其制备方法
CN1161971A (zh) * 1997-01-03 1997-10-15 石家庄制药集团有限公司 一种阿齐霉素结晶及其制备方法
CA2245398C (en) * 1998-08-21 2002-01-29 Apotex Inc. Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof
US6365574B2 (en) * 1998-11-30 2002-04-02 Teva Pharmaceutical Industries Ltd. Ethanolate of azithromycin, process for manufacture, and pharmaceutical compositions thereof
KR100491183B1 (ko) * 2001-03-21 2005-05-25 한미약품 주식회사 아지트로마이신의 제조방법 및 이 방법에 사용되는9-데옥소-9에이-아자-9에이-호모에리트로마이신 에이의결정성 수화물
BR0209918A (pt) * 2001-05-22 2004-03-30 Pfizer Prod Inc Formas cristalinas da azitromicina

Also Published As

Publication number Publication date
CA2352562A1 (en) 2000-06-08
US6365574B2 (en) 2002-04-02
LV12735B (en) 2002-03-20
PT1152765E (pt) 2004-12-31
ES2229804T3 (es) 2005-04-16
ATE279200T1 (de) 2004-10-15
HK1043725B (zh) 2005-05-06
AP2001002183A0 (en) 2001-06-30
AP1709A (en) 2007-02-27
DE69921192T2 (de) 2006-02-16
PL347971A1 (en) 2002-05-06
US20020007049A1 (en) 2002-01-17
EP1152765B1 (en) 2004-10-13
KR100603226B1 (ko) 2006-08-28
DE69921192D1 (de) 2004-11-18
HK1043725A1 (en) 2002-09-27
AU3106500A (en) 2000-06-19
EP1152765A1 (en) 2001-11-14
PL197894B1 (pl) 2008-05-30
CN1273142C (zh) 2006-09-06
ZA200104312B (en) 2001-11-28
BG105547A (en) 2001-12-31
CZ20011886A3 (cs) 2001-10-17
JP2002531409A (ja) 2002-09-24
RU2240124C2 (ru) 2004-11-20
IL143376A0 (en) 2002-04-21
HUP0104241A2 (hu) 2002-03-28
KR20010099806A (ko) 2001-11-09
CN100339384C (zh) 2007-09-26
CN1334735A (zh) 2002-02-06
DK1152765T3 (da) 2005-01-31
NZ512496A (en) 2003-02-28
EP1152765A4 (en) 2002-07-17
EP1484062A1 (en) 2004-12-08
LV12735A (en) 2001-10-20
RO121408B1 (ro) 2007-05-30
CN1737008A (zh) 2006-02-22
AU768219B2 (en) 2003-12-04
HUP0104241A3 (en) 2003-12-29
WO2000032203A1 (en) 2000-06-08

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Effective date: 20090803