SI20639A - Etanolat azitromicina, postopek za njegovo pripravo in njegovi farmacevtski sestavki - Google Patents
Etanolat azitromicina, postopek za njegovo pripravo in njegovi farmacevtski sestavki Download PDFInfo
- Publication number
- SI20639A SI20639A SI9920086A SI9920086A SI20639A SI 20639 A SI20639 A SI 20639A SI 9920086 A SI9920086 A SI 9920086A SI 9920086 A SI9920086 A SI 9920086A SI 20639 A SI20639 A SI 20639A
- Authority
- SI
- Slovenia
- Prior art keywords
- azithromycin
- ethanolate
- water
- suspension
- ethanol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11029898P | 1998-11-30 | 1998-11-30 | |
PCT/US1999/028368 WO2000032203A1 (en) | 1998-11-30 | 1999-11-30 | Ethanolate of azithromycin, process for manufacture, and pharmaceutical compositions thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
SI20639A true SI20639A (sl) | 2002-02-28 |
Family
ID=22332273
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI9920086A SI20639A (sl) | 1998-11-30 | 1999-11-30 | Etanolat azitromicina, postopek za njegovo pripravo in njegovi farmacevtski sestavki |
Country Status (26)
Country | Link |
---|---|
US (1) | US6365574B2 (hu) |
EP (2) | EP1152765B1 (hu) |
JP (1) | JP2002531409A (hu) |
KR (1) | KR100603226B1 (hu) |
CN (2) | CN1273142C (hu) |
AP (1) | AP1709A (hu) |
AT (1) | ATE279200T1 (hu) |
AU (1) | AU768219B2 (hu) |
BG (1) | BG105547A (hu) |
CA (1) | CA2352562A1 (hu) |
CZ (1) | CZ20011886A3 (hu) |
DE (1) | DE69921192T2 (hu) |
DK (1) | DK1152765T3 (hu) |
ES (1) | ES2229804T3 (hu) |
HK (1) | HK1043725B (hu) |
HU (1) | HUP0104241A3 (hu) |
IL (1) | IL143376A0 (hu) |
LV (1) | LV12735B (hu) |
NZ (1) | NZ512496A (hu) |
PL (1) | PL197894B1 (hu) |
PT (1) | PT1152765E (hu) |
RO (1) | RO121408B1 (hu) |
RU (1) | RU2240124C2 (hu) |
SI (1) | SI20639A (hu) |
WO (1) | WO2000032203A1 (hu) |
ZA (1) | ZA200104312B (hu) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HRP20020231A2 (en) * | 2002-03-18 | 2003-12-31 | Pliva D D | ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A |
TW546302B (en) * | 1998-05-08 | 2003-08-11 | Biochemie Sa | Improvements in macrolide production |
CA2245398C (en) | 1998-08-21 | 2002-01-29 | Apotex Inc. | Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof |
US6365574B2 (en) * | 1998-11-30 | 2002-04-02 | Teva Pharmaceutical Industries Ltd. | Ethanolate of azithromycin, process for manufacture, and pharmaceutical compositions thereof |
HU229488B1 (hu) * | 2000-11-27 | 2014-01-28 | Sandoz Ag | Eljárás makrolid hidrátok elõállítására |
CN100341886C (zh) * | 2000-11-27 | 2007-10-10 | 桑多斯股份公司 | 大环内酯类化合物的溶剂化物 |
KR100431431B1 (ko) * | 2001-04-25 | 2004-05-14 | 한미약품 주식회사 | 아지트로마이신 수화물의 1,2-프로필렌글리콜 내포화합물,그의 제조방법 및 그의 약학적 조성물 |
EP1671978A1 (en) * | 2001-05-22 | 2006-06-21 | Pfizer Products Inc. | New Cristal Form of Azithromycin |
US6861413B2 (en) | 2001-05-22 | 2005-03-01 | Pfizer Inc. | Stable non-dihydrate azithromycin oral suspensions |
BR0209918A (pt) | 2001-05-22 | 2004-03-30 | Pfizer Prod Inc | Formas cristalinas da azitromicina |
HUP0402291A2 (hu) | 2001-10-18 | 2005-03-29 | Teva Pharmaceutical Industries Ltd. | Stabilizált azithromycin összetételek, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények |
US20080149521A9 (en) * | 2001-10-18 | 2008-06-26 | Michael Pesachovich | Methods of stabilizing azithromycin |
EP1541134A3 (en) * | 2001-10-18 | 2007-06-06 | Teva Pharmaceutical Industries Limited | Stabilized azithromycin compositions |
NZ532707A (en) * | 2001-12-21 | 2006-07-28 | Pfizer Prod Inc | Directly compressible formulations of azithromycin |
PL371125A1 (en) * | 2001-12-21 | 2005-06-13 | Pfizer Products Inc. | Methods for wet granulating azithromycin |
EP1478347A1 (en) * | 2002-02-01 | 2004-11-24 | Pfizer Products Inc. | Dry granulated formulations of azithromycin |
HRP20020614A2 (en) * | 2002-07-22 | 2004-06-30 | PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o. | Rhombic pseudopolymorph of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin a |
US20050013835A1 (en) * | 2003-07-15 | 2005-01-20 | Pfizer Inc. | Stable non-dihydrate azithromycin oral suspensions |
US20050101547A1 (en) * | 2003-11-06 | 2005-05-12 | Sadatrezaei Mohsen | Stabilized azithromycin composition |
US6984403B2 (en) * | 2003-12-04 | 2006-01-10 | Pfizer Inc. | Azithromycin dosage forms with reduced side effects |
CA2547597A1 (en) * | 2003-12-04 | 2005-06-16 | Pfizer Products Inc. | Multiparticulate compositions with improved stability |
WO2005053639A2 (en) * | 2003-12-04 | 2005-06-16 | Pfizer Products Inc. | Controlled release multiparticulates formed with dissolution enhancers |
WO2005053652A1 (en) | 2003-12-04 | 2005-06-16 | Pfizer Products Inc. | Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride |
BRPI0417338A (pt) * | 2003-12-04 | 2007-04-17 | Pfizer Prod Inc | formas de dosagem de azitromicina multiparticulada por processos a base de lìquido |
JP2007513147A (ja) * | 2003-12-04 | 2007-05-24 | ファイザー・プロダクツ・インク | 押し出し機を使用して、好ましくはポロキサマーとグリセリドを含有する多粒子結晶性医薬組成物を製造するための噴霧凝結方法 |
SI1691787T1 (sl) * | 2003-12-04 | 2008-10-31 | Pfizer Prod Inc | Postopek za pripravo farmacevtskih produktov iz več delcev |
US7943585B2 (en) | 2003-12-22 | 2011-05-17 | Sandoz, Inc. | Extended release antibiotic composition |
US20060116336A1 (en) * | 2004-03-17 | 2006-06-01 | American Pharmaceutical Partners, Inc. | Lyophilized azithromycin formulation |
US7468428B2 (en) * | 2004-03-17 | 2008-12-23 | App Pharmaceuticals, Llc | Lyophilized azithromycin formulation |
US7683162B2 (en) * | 2004-08-30 | 2010-03-23 | Taro Pharmaceutical Industries Limited | Process of preparing a crystalline azithromycin monohydrate |
JP2008524318A (ja) * | 2004-12-21 | 2008-07-10 | ファイザー・プロダクツ・インク | 安定なアジスロマイシン非二水和物の経口用懸濁液剤 |
US20060198895A1 (en) * | 2005-03-07 | 2006-09-07 | Kotliar Eleonora M | Azithromycin powder for oral suspension compositions |
WO2010103119A1 (en) | 2009-03-13 | 2010-09-16 | Da Volterra | Compositions and methods for elimination of gram-negative bacteria |
WO2010121187A2 (en) * | 2009-04-17 | 2010-10-21 | Micell Techologies, Inc. | Stents having controlled elution |
WO2013088274A1 (en) | 2011-12-14 | 2013-06-20 | Wockhardt Limited | Anhydrous amorphous azithromycin composition free of azithromycin dihydrate |
CN103983730B (zh) * | 2014-06-11 | 2015-09-30 | 北京市药品检验所 | 阿奇霉素或其制剂中的杂质检查方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI8110592A8 (en) | 1981-03-06 | 1996-06-30 | Pliva Pharm & Chem Works | Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof |
US4474768A (en) * | 1982-07-19 | 1984-10-02 | Pfizer Inc. | N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor |
MX12213A (es) | 1987-07-09 | 1993-05-01 | Pfizer | Metodo de preparacion de dihidrato de azitromicina cristalino |
WO1989002271A1 (en) * | 1987-09-10 | 1989-03-23 | Pfizer | Azithromycin and derivatives as antiprotozoal agents |
CN1093370A (zh) * | 1993-12-10 | 1994-10-12 | 北京市集才药物研究所 | 一种新的阿齐红霉素结晶及其制备方法 |
CN1161971A (zh) * | 1997-01-03 | 1997-10-15 | 石家庄制药集团有限公司 | 一种阿齐霉素结晶及其制备方法 |
CA2245398C (en) * | 1998-08-21 | 2002-01-29 | Apotex Inc. | Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof |
US6365574B2 (en) * | 1998-11-30 | 2002-04-02 | Teva Pharmaceutical Industries Ltd. | Ethanolate of azithromycin, process for manufacture, and pharmaceutical compositions thereof |
KR100491183B1 (ko) * | 2001-03-21 | 2005-05-25 | 한미약품 주식회사 | 아지트로마이신의 제조방법 및 이 방법에 사용되는9-데옥소-9에이-아자-9에이-호모에리트로마이신 에이의결정성 수화물 |
BR0209918A (pt) * | 2001-05-22 | 2004-03-30 | Pfizer Prod Inc | Formas cristalinas da azitromicina |
-
1999
- 1999-11-30 US US09/451,738 patent/US6365574B2/en not_active Expired - Lifetime
- 1999-11-30 JP JP2000584898A patent/JP2002531409A/ja active Pending
- 1999-11-30 CZ CZ20011886A patent/CZ20011886A3/cs unknown
- 1999-11-30 ES ES99965069T patent/ES2229804T3/es not_active Expired - Lifetime
- 1999-11-30 IL IL14337699A patent/IL143376A0/xx unknown
- 1999-11-30 SI SI9920086A patent/SI20639A/sl not_active IP Right Cessation
- 1999-11-30 EP EP99965069A patent/EP1152765B1/en not_active Expired - Lifetime
- 1999-11-30 AT AT99965069T patent/ATE279200T1/de not_active IP Right Cessation
- 1999-11-30 AP APAP/P/2001/002183A patent/AP1709A/en active
- 1999-11-30 KR KR1020017006669A patent/KR100603226B1/ko not_active IP Right Cessation
- 1999-11-30 RU RU2001118035/15A patent/RU2240124C2/ru not_active IP Right Cessation
- 1999-11-30 AU AU31065/00A patent/AU768219B2/en not_active Ceased
- 1999-11-30 RO ROA200100573A patent/RO121408B1/ro unknown
- 1999-11-30 WO PCT/US1999/028368 patent/WO2000032203A1/en active IP Right Grant
- 1999-11-30 NZ NZ512496A patent/NZ512496A/xx unknown
- 1999-11-30 CN CNB998158542A patent/CN1273142C/zh not_active Expired - Fee Related
- 1999-11-30 CA CA002352562A patent/CA2352562A1/en not_active Abandoned
- 1999-11-30 CN CNB2005100785525A patent/CN100339384C/zh not_active Expired - Fee Related
- 1999-11-30 DE DE69921192T patent/DE69921192T2/de not_active Expired - Fee Related
- 1999-11-30 DK DK99965069T patent/DK1152765T3/da active
- 1999-11-30 EP EP04014455A patent/EP1484062A1/en not_active Withdrawn
- 1999-11-30 HU HU0104241A patent/HUP0104241A3/hu unknown
- 1999-11-30 PT PT99965069T patent/PT1152765E/pt unknown
- 1999-11-30 PL PL347971A patent/PL197894B1/pl not_active IP Right Cessation
-
2001
- 2001-05-25 ZA ZA200104312A patent/ZA200104312B/en unknown
- 2001-05-29 BG BG105547A patent/BG105547A/xx unknown
- 2001-06-22 LV LVP-01-79A patent/LV12735B/en unknown
-
2002
- 2002-04-12 HK HK02102775.5A patent/HK1043725B/zh not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
IF | Valid on the event date | ||
KO00 | Lapse of patent |
Effective date: 20090803 |