BG105547A - Ethanolate of azithromycin, process for manufacture, and pharmaceutical compositions thereof - Google Patents

Ethanolate of azithromycin, process for manufacture, and pharmaceutical compositions thereof

Info

Publication number
BG105547A
BG105547A BG105547A BG10554701A BG105547A BG 105547 A BG105547 A BG 105547A BG 105547 A BG105547 A BG 105547A BG 10554701 A BG10554701 A BG 10554701A BG 105547 A BG105547 A BG 105547A
Authority
BG
Bulgaria
Prior art keywords
azithromycin
pharmaceutical compositions
ethanolate
manufacture
disclosed
Prior art date
Application number
BG105547A
Other languages
Bulgarian (bg)
English (en)
Inventor
Claude Singer
Judith Aronhime
Original Assignee
Teva Pharmaceutical Industries Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22332273&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG105547(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teva Pharmaceutical Industries Ltd. filed Critical Teva Pharmaceutical Industries Ltd.
Publication of BG105547A publication Critical patent/BG105547A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
BG105547A 1998-11-30 2001-05-29 Ethanolate of azithromycin, process for manufacture, and pharmaceutical compositions thereof BG105547A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11029898P 1998-11-30 1998-11-30
PCT/US1999/028368 WO2000032203A1 (en) 1998-11-30 1999-11-30 Ethanolate of azithromycin, process for manufacture, and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
BG105547A true BG105547A (en) 2001-12-31

Family

ID=22332273

Family Applications (1)

Application Number Title Priority Date Filing Date
BG105547A BG105547A (en) 1998-11-30 2001-05-29 Ethanolate of azithromycin, process for manufacture, and pharmaceutical compositions thereof

Country Status (26)

Country Link
US (1) US6365574B2 (hu)
EP (2) EP1484062A1 (hu)
JP (1) JP2002531409A (hu)
KR (1) KR100603226B1 (hu)
CN (2) CN1273142C (hu)
AP (1) AP1709A (hu)
AT (1) ATE279200T1 (hu)
AU (1) AU768219B2 (hu)
BG (1) BG105547A (hu)
CA (1) CA2352562A1 (hu)
CZ (1) CZ20011886A3 (hu)
DE (1) DE69921192T2 (hu)
DK (1) DK1152765T3 (hu)
ES (1) ES2229804T3 (hu)
HK (1) HK1043725B (hu)
HU (1) HUP0104241A3 (hu)
IL (1) IL143376A0 (hu)
LV (1) LV12735B (hu)
NZ (1) NZ512496A (hu)
PL (1) PL197894B1 (hu)
PT (1) PT1152765E (hu)
RO (1) RO121408B1 (hu)
RU (1) RU2240124C2 (hu)
SI (1) SI20639A (hu)
WO (1) WO2000032203A1 (hu)
ZA (1) ZA200104312B (hu)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20020231A2 (en) * 2002-03-18 2003-12-31 Pliva D D ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A
TW546302B (en) * 1998-05-08 2003-08-11 Biochemie Sa Improvements in macrolide production
CA2245398C (en) 1998-08-21 2002-01-29 Apotex Inc. Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof
WO2000032203A1 (en) * 1998-11-30 2000-06-08 Teva Pharmaceutical Industries Ltd. Ethanolate of azithromycin, process for manufacture, and pharmaceutical compositions thereof
CA2429639C (en) * 2000-11-27 2009-07-14 Biochemie S.A. Stable azithromycin monohydrate
UA76967C2 (uk) * 2000-11-27 2006-10-16 Сандоз Аг Азитроміцин у формі моногідрату, фармацевтична композиція та спосіб його одержання
KR100431431B1 (ko) * 2001-04-25 2004-05-14 한미약품 주식회사 아지트로마이신 수화물의 1,2-프로필렌글리콜 내포화합물,그의 제조방법 및 그의 약학적 조성물
PL367091A1 (en) * 2001-05-22 2005-02-21 Pfizer Products Inc. Crystal forms of azithromycin
EP1652851A1 (en) 2001-05-22 2006-05-03 Pfizer Products Inc. New crystal form of Azithromycin
US6861413B2 (en) * 2001-05-22 2005-03-01 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
US20080149521A9 (en) * 2001-10-18 2008-06-26 Michael Pesachovich Methods of stabilizing azithromycin
EP1446010B1 (en) 2001-10-18 2009-04-15 Teva Pharmaceutical Industries Ltd. Stabilized azithromycin compositions
EP1541134A3 (en) * 2001-10-18 2007-06-06 Teva Pharmaceutical Industries Limited Stabilized azithromycin compositions
AU2002348884A1 (en) * 2001-12-21 2003-07-09 Pfizer Products Inc. Directly compressible formulations of azithromycin
EP1455757A2 (en) * 2001-12-21 2004-09-15 Pfizer Products Inc. Methods for wet granulating azithromycin
MXPA04007427A (es) * 2002-02-01 2004-10-11 Pfizer Prod Inc Formulaciones de azitromicina granuladas por via seca.
HRP20020614A2 (en) * 2002-07-22 2004-06-30 PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o. Rhombic pseudopolymorph of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin a
US20050013835A1 (en) * 2003-07-15 2005-01-20 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
US20050101547A1 (en) * 2003-11-06 2005-05-12 Sadatrezaei Mohsen Stabilized azithromycin composition
JP2007513145A (ja) * 2003-12-04 2007-05-24 ファイザー・プロダクツ・インク 医薬用多微粒子の製造方法
JP2007513147A (ja) * 2003-12-04 2007-05-24 ファイザー・プロダクツ・インク 押し出し機を使用して、好ましくはポロキサマーとグリセリドを含有する多粒子結晶性医薬組成物を製造するための噴霧凝結方法
JP2007513139A (ja) * 2003-12-04 2007-05-24 ファイザー・プロダクツ・インク 安定性の改善した多粒子組成物
WO2005053639A2 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Controlled release multiparticulates formed with dissolution enhancers
AU2004294818A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Azithromycin multiparticulate dosage forms by liquid-based processes
WO2005053652A1 (en) 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride
US6984403B2 (en) * 2003-12-04 2006-01-10 Pfizer Inc. Azithromycin dosage forms with reduced side effects
US7943585B2 (en) 2003-12-22 2011-05-17 Sandoz, Inc. Extended release antibiotic composition
US20060116336A1 (en) * 2004-03-17 2006-06-01 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation
US7468428B2 (en) * 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
US7683162B2 (en) * 2004-08-30 2010-03-23 Taro Pharmaceutical Industries Limited Process of preparing a crystalline azithromycin monohydrate
EP1830860A2 (en) * 2004-12-21 2007-09-12 Pfizer Products Incorporated Stable non-dihydrate azithromycin oral suspensions
US20060198895A1 (en) * 2005-03-07 2006-09-07 Kotliar Eleonora M Azithromycin powder for oral suspension compositions
CN102413826A (zh) 2009-03-13 2012-04-11 达·沃尔泰拉公司 用于消除革兰氏阴性菌的组合物和方法
EP3366326A1 (en) * 2009-04-17 2018-08-29 Micell Technologies, Inc. Stents having controlled elution
WO2013088274A1 (en) 2011-12-14 2013-06-20 Wockhardt Limited Anhydrous amorphous azithromycin composition free of azithromycin dihydrate
CN103983730B (zh) * 2014-06-11 2015-09-30 北京市药品检验所 阿奇霉素或其制剂中的杂质检查方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU43006B (en) 1981-03-06 1989-02-28 Pliva Pharm & Chem Works Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
MX12213A (es) * 1987-07-09 1993-05-01 Pfizer Metodo de preparacion de dihidrato de azitromicina cristalino
WO1989002271A1 (en) * 1987-09-10 1989-03-23 Pfizer Azithromycin and derivatives as antiprotozoal agents
CN1093370A (zh) * 1993-12-10 1994-10-12 北京市集才药物研究所 一种新的阿齐红霉素结晶及其制备方法
CN1161971A (zh) * 1997-01-03 1997-10-15 石家庄制药集团有限公司 一种阿齐霉素结晶及其制备方法
CA2245398C (en) * 1998-08-21 2002-01-29 Apotex Inc. Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof
WO2000032203A1 (en) * 1998-11-30 2000-06-08 Teva Pharmaceutical Industries Ltd. Ethanolate of azithromycin, process for manufacture, and pharmaceutical compositions thereof
KR100491183B1 (ko) * 2001-03-21 2005-05-25 한미약품 주식회사 아지트로마이신의 제조방법 및 이 방법에 사용되는9-데옥소-9에이-아자-9에이-호모에리트로마이신 에이의결정성 수화물
PL367091A1 (en) * 2001-05-22 2005-02-21 Pfizer Products Inc. Crystal forms of azithromycin

Also Published As

Publication number Publication date
KR20010099806A (ko) 2001-11-09
HK1043725A1 (en) 2002-09-27
LV12735B (en) 2002-03-20
CN1273142C (zh) 2006-09-06
PT1152765E (pt) 2004-12-31
PL347971A1 (en) 2002-05-06
AU3106500A (en) 2000-06-19
US6365574B2 (en) 2002-04-02
WO2000032203A1 (en) 2000-06-08
CN1737008A (zh) 2006-02-22
HK1043725B (zh) 2005-05-06
DE69921192T2 (de) 2006-02-16
EP1152765A4 (en) 2002-07-17
CZ20011886A3 (cs) 2001-10-17
EP1152765A1 (en) 2001-11-14
LV12735A (en) 2001-10-20
DK1152765T3 (da) 2005-01-31
HUP0104241A2 (hu) 2002-03-28
HUP0104241A3 (en) 2003-12-29
RO121408B1 (ro) 2007-05-30
CN100339384C (zh) 2007-09-26
SI20639A (sl) 2002-02-28
CN1334735A (zh) 2002-02-06
IL143376A0 (en) 2002-04-21
CA2352562A1 (en) 2000-06-08
AP2001002183A0 (en) 2001-06-30
DE69921192D1 (de) 2004-11-18
AP1709A (en) 2007-02-27
JP2002531409A (ja) 2002-09-24
RU2240124C2 (ru) 2004-11-20
KR100603226B1 (ko) 2006-08-28
EP1484062A1 (en) 2004-12-08
NZ512496A (en) 2003-02-28
AU768219B2 (en) 2003-12-04
US20020007049A1 (en) 2002-01-17
EP1152765B1 (en) 2004-10-13
ATE279200T1 (de) 2004-10-15
PL197894B1 (pl) 2008-05-30
ZA200104312B (en) 2001-11-28
ES2229804T3 (es) 2005-04-16

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