SI1597381T1 - Proizvodnja modificiranih glikoproteinov, ki imajo vežśkratno razvejano strukturo - Google Patents

Proizvodnja modificiranih glikoproteinov, ki imajo vežśkratno razvejano strukturo

Info

Publication number
SI1597381T1
SI1597381T1 SI200431362T SI200431362T SI1597381T1 SI 1597381 T1 SI1597381 T1 SI 1597381T1 SI 200431362 T SI200431362 T SI 200431362T SI 200431362 T SI200431362 T SI 200431362T SI 1597381 T1 SI1597381 T1 SI 1597381T1
Authority
SI
Slovenia
Prior art keywords
host cells
production
modified
sugar
glycoproteins
Prior art date
Application number
SI200431362T
Other languages
English (en)
Other versions
SI1597381T2 (sl
Inventor
Piotr Bobrowicz
Stephen R Hamilton
Tillman U Gerngross
Stefan Wildt
Byung-Kwon Choi
Juergen Hermann Nett
Robert C Davidson
Original Assignee
Glycofi Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32911943&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1597381(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US10/371,877 external-priority patent/US7449308B2/en
Application filed by Glycofi Inc filed Critical Glycofi Inc
Publication of SI1597381T1 publication Critical patent/SI1597381T1/sl
Publication of SI1597381T2 publication Critical patent/SI1597381T2/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1051Hexosyltransferases (2.4.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/05Fusion polypeptide containing a localisation/targetting motif containing a GOLGI retention signal
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
SI200431362T 2003-02-20 2004-02-20 Proizvodnja modificiranih glikoproteinov, ki imajo veäśkratno razvejano strukturo SI1597381T2 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10/371,877 US7449308B2 (en) 2000-06-28 2003-02-20 Combinatorial DNA library for producing modified N-glycans in lower eukaryotes
US10/680,963 US7598055B2 (en) 2000-06-28 2003-10-07 N-acetylglucosaminyltransferase III expression in lower eukaryotes
EP04713388.9A EP1597381B2 (en) 2003-02-20 2004-02-20 Production of modified glycoproteins having multiple antennary structures
PCT/US2004/005191 WO2004074461A2 (en) 2003-02-20 2004-02-20 Production of modified glycoproteins having multiple antennary structures

Publications (2)

Publication Number Publication Date
SI1597381T1 true SI1597381T1 (sl) 2010-04-30
SI1597381T2 SI1597381T2 (sl) 2013-08-30

Family

ID=32911943

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200431310T SI1599595T2 (sl) 2003-02-20 2004-02-20 N -acetilglukosaminil transferasa iii izraĺ˝ena v niĺ˝jih eukariotah
SI200431362T SI1597381T2 (sl) 2003-02-20 2004-02-20 Proizvodnja modificiranih glikoproteinov, ki imajo veäśkratno razvejano strukturo

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SI200431310T SI1599595T2 (sl) 2003-02-20 2004-02-20 N -acetilglukosaminil transferasa iii izraĺ˝ena v niĺ˝jih eukariotah

Country Status (11)

Country Link
US (3) US7598055B2 (sl)
EP (3) EP2080809B1 (sl)
JP (4) JP4758335B2 (sl)
AT (3) ATE452201T1 (sl)
AU (3) AU2004213859B2 (sl)
CA (3) CA2516520C (sl)
DE (2) DE602004024649D1 (sl)
ES (3) ES2384929T3 (sl)
PT (2) PT1597381E (sl)
SI (2) SI1599595T2 (sl)
WO (2) WO2004074458A2 (sl)

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