SI1309585T1 - Novi derivati indola in njihova uporaba kot zdravila - Google Patents

Novi derivati indola in njihova uporaba kot zdravila

Info

Publication number
SI1309585T1
SI1309585T1 SI200130834T SI200130834T SI1309585T1 SI 1309585 T1 SI1309585 T1 SI 1309585T1 SI 200130834 T SI200130834 T SI 200130834T SI 200130834 T SI200130834 T SI 200130834T SI 1309585 T1 SI1309585 T1 SI 1309585T1
Authority
SI
Slovenia
Prior art keywords
medicaments
indole derivatives
novel indole
novel
derivatives
Prior art date
Application number
SI200130834T
Other languages
English (en)
Inventor
Peter Emig
Gerald Bacher
Dietmar Reichert
Silke Baasner
Beate Aue
Bernd Nickel
Eckhard Gunther
Original Assignee
Aeterna Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aeterna Zentaris Gmbh filed Critical Aeterna Zentaris Gmbh
Publication of SI1309585T1 publication Critical patent/SI1309585T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
SI200130834T 2000-07-28 2001-07-26 Novi derivati indola in njihova uporaba kot zdravila SI1309585T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10037310A DE10037310A1 (de) 2000-07-28 2000-07-28 Neue Indolderivate und deren Verwendung als Arzneimittel
EP01969522A EP1309585B1 (de) 2000-07-28 2001-07-26 Neue indolderivate und deren verwendung als arzneimittel
PCT/EP2001/008644 WO2002010152A2 (de) 2000-07-28 2001-07-26 Neue indolderivate und deren verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
SI1309585T1 true SI1309585T1 (sl) 2008-08-31

Family

ID=7650860

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200130834T SI1309585T1 (sl) 2000-07-28 2001-07-26 Novi derivati indola in njihova uporaba kot zdravila

Country Status (31)

Country Link
US (3) US7365081B2 (sl)
EP (3) EP2163552A1 (sl)
JP (1) JP5113973B2 (sl)
KR (1) KR100810453B1 (sl)
CN (1) CN1215066C (sl)
AR (1) AR055209A1 (sl)
AT (1) ATE392420T1 (sl)
AU (2) AU2001289758B2 (sl)
BG (1) BG66457B1 (sl)
BR (1) BR0112807A (sl)
CA (3) CA2354210C (sl)
CY (1) CY1108770T1 (sl)
CZ (1) CZ304197B6 (sl)
DE (2) DE10037310A1 (sl)
DK (1) DK1309585T3 (sl)
ES (1) ES2303532T3 (sl)
HK (1) HK1058201A1 (sl)
HU (1) HU229254B1 (sl)
IL (2) IL153930A0 (sl)
MX (1) MXPA03000644A (sl)
NO (1) NO324594B1 (sl)
NZ (1) NZ524404A (sl)
PL (1) PL208673B1 (sl)
PT (1) PT1309585E (sl)
RU (1) RU2270196C9 (sl)
SI (1) SI1309585T1 (sl)
SK (1) SK288085B6 (sl)
TW (1) TWI291955B (sl)
UA (1) UA80670C2 (sl)
WO (1) WO2002010152A2 (sl)
ZA (1) ZA200300584B (sl)

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EP1484329A1 (de) * 2003-06-06 2004-12-08 Zentaris GmbH Indolderivate mit Apoptose induzierender Wirkung
US7205299B2 (en) * 2003-06-05 2007-04-17 Zentaris Gmbh Indole derivatives having an apoptosis-inducing effect
EP1641777A1 (de) * 2003-06-05 2006-04-05 Zentaris GmbH Indolderivate mit apoptose induzierender wirkung
US7211588B2 (en) * 2003-07-25 2007-05-01 Zentaris Gmbh N-substituted indolyl-3-glyoxylamides, their use as medicaments and process for their preparation
US20050124623A1 (en) 2003-11-26 2005-06-09 Bender John A. Diazaindole-dicarbonyl-piperazinyl antiviral agents
US20060100432A1 (en) 2004-11-09 2006-05-11 Matiskella John D Crystalline materials of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione
US8399666B2 (en) 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
US7977359B2 (en) 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
GB2431927B (en) 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
US7851476B2 (en) 2005-12-14 2010-12-14 Bristol-Myers Squibb Company Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-YL)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-C]pyridin-3-YL]-1,2-dioxoethyl]-piperazine
US7807671B2 (en) 2006-04-25 2010-10-05 Bristol-Myers Squibb Company Diketo-piperazine and piperidine derivatives as antiviral agents
CA2660704A1 (en) 2006-08-07 2008-02-14 Ironwood Pharmaceuticals, Inc. Indole compounds
JP5791500B2 (ja) 2008-05-23 2015-10-07 パンミラ ファーマシューティカルズ，エルエルシー． ５−リポキシゲナーゼ活性化タンパク質阻害剤
AR084433A1 (es) 2010-12-22 2013-05-15 Ironwood Pharmaceuticals Inc Inhibidores de la faah y composiciones farmaceuticas que los contienen

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JP5241235B2 (ja) * 2007-02-28 2013-07-17 イビデン株式会社 ハニカム構造体の製造方法
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Also Published As

Publication number Publication date
IL153930A (en) 2008-11-03
CA2354210A1 (en) 2002-01-28
RU2270196C2 (ru) 2006-02-20
DE10037310A1 (de) 2002-02-07
CN1215066C (zh) 2005-08-17
EP1309585B1 (de) 2008-04-16
BR0112807A (pt) 2003-07-01
DE50113867D1 (de) 2008-05-29
JP2004505075A (ja) 2004-02-19
CA2354210C (en) 2010-09-14
EP1309585A2 (de) 2003-05-14
HU229254B1 (en) 2013-10-28
MXPA03000644A (es) 2003-06-06
IL153930A0 (en) 2003-07-31
KR20030017658A (ko) 2003-03-03
CZ304197B6 (cs) 2013-12-27
PL208673B1 (pl) 2011-05-31
AU2001289758B2 (en) 2006-07-06
SK288085B6 (sk) 2013-06-03
DK1309585T3 (da) 2008-06-23
US7989453B2 (en) 2011-08-02
BG66457B1 (bg) 2014-10-31
US20080108819A1 (en) 2008-05-08
NO20030382D0 (no) 2003-01-24
BG107560A (bg) 2003-10-31
US7365081B2 (en) 2008-04-29
CY1108770T1 (el) 2014-04-09
CZ2003500A3 (cs) 2004-03-17
CN1447805A (zh) 2003-10-08
KR100810453B1 (ko) 2008-03-07
US20030100597A1 (en) 2003-05-29
NO324594B1 (no) 2007-11-26
SK2222003A3 (en) 2004-04-06
CA2704691A1 (en) 2002-01-28
UA80670C2 (en) 2007-10-25
US20080153875A1 (en) 2008-06-26
WO2002010152A3 (de) 2002-08-01
ES2303532T3 (es) 2008-08-16
EP1939195A1 (de) 2008-07-02
CA2704693A1 (en) 2002-01-28
US8008324B2 (en) 2011-08-30
EP2163552A1 (de) 2010-03-17
AU8975801A (en) 2002-02-13
NZ524404A (en) 2004-08-27
ZA200300584B (en) 2003-07-18
JP5113973B2 (ja) 2013-01-09
PT1309585E (pt) 2008-06-09
AR055209A1 (es) 2007-08-15
ATE392420T1 (de) 2008-05-15
PL361356A1 (en) 2004-10-04
NO20030382L (no) 2003-02-20
RU2270196C9 (ru) 2007-11-27
HK1058201A1 (en) 2004-05-07
TWI291955B (en) 2008-01-01
HUP0300677A2 (hu) 2003-11-28
WO2002010152A2 (de) 2002-02-07

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