SI1179533T1 - Salt of naphthyridine carboxylic acid derivative - Google Patents
Salt of naphthyridine carboxylic acid derivativeInfo
- Publication number
- SI1179533T1 SI1179533T1 SI9830595T SI9830595T SI1179533T1 SI 1179533 T1 SI1179533 T1 SI 1179533T1 SI 9830595 T SI9830595 T SI 9830595T SI 9830595 T SI9830595 T SI 9830595T SI 1179533 T1 SI1179533 T1 SI 1179533T1
- Authority
- SI
- Slovenia
- Prior art keywords
- salt
- carboxylic acid
- acid derivative
- naphthyridine carboxylic
- naphthyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C309/04—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing only one sulfo group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR19970009840 | 1997-03-21 | ||
| EP98908300A EP0981527B1 (en) | 1997-03-21 | 1998-03-20 | Salt of naphthyridine carboxylic acid derivative |
| EP01203507A EP1179533B1 (en) | 1997-03-21 | 1998-03-20 | Salt of naphthyridine carboxylic acid derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1179533T1 true SI1179533T1 (en) | 2004-04-30 |
Family
ID=19500439
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9830418T SI0981527T1 (en) | 1997-03-21 | 1998-03-20 | Salt of naphthyridine carboxylic acid derivative |
| SI9830595T SI1179533T1 (en) | 1997-03-21 | 1998-03-20 | Salt of naphthyridine carboxylic acid derivative |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9830418T SI0981527T1 (en) | 1997-03-21 | 1998-03-20 | Salt of naphthyridine carboxylic acid derivative |
Country Status (39)
| Country | Link |
|---|---|
| US (9) | US7700617B2 ( ) |
| EP (2) | EP0981527B1 ( ) |
| JP (3) | JP3759962B2 ( ) |
| KR (1) | KR100266499B1 ( ) |
| CN (1) | CN1131229C ( ) |
| AP (1) | AP1331A ( ) |
| AR (1) | AR012125A1 ( ) |
| AT (2) | ATE239724T1 ( ) |
| AU (1) | AU726634B2 ( ) |
| BG (1) | BG63972B1 ( ) |
| BR (1) | BR9808290A ( ) |
| CA (1) | CA2283671C ( ) |
| CZ (2) | CZ288673B6 ( ) |
| DE (2) | DE69821147T2 ( ) |
| DK (2) | DK0981527T3 ( ) |
| DZ (1) | DZ2448A1 ( ) |
| EA (1) | EA001674B1 ( ) |
| ES (2) | ES2198697T3 ( ) |
| HK (1) | HK1026698A1 ( ) |
| HU (2) | HU227536B1 ( ) |
| ID (1) | ID22681A ( ) |
| IL (2) | IL131812A0 ( ) |
| IN (1) | IN188178B ( ) |
| IS (2) | IS2093B ( ) |
| MA (1) | MA24500A1 ( ) |
| MY (1) | MY137653A ( ) |
| NO (1) | NO312515B1 ( ) |
| NZ (1) | NZ337748A ( ) |
| OA (1) | OA11161A ( ) |
| PE (1) | PE67999A1 ( ) |
| PL (1) | PL191815B1 ( ) |
| PT (2) | PT981527E ( ) |
| SA (1) | SA98181055B1 ( ) |
| SI (2) | SI0981527T1 ( ) |
| SK (1) | SK284107B6 ( ) |
| TR (1) | TR199902313T2 ( ) |
| UA (1) | UA56218C2 ( ) |
| WO (1) | WO1998042705A1 ( ) |
| ZA (1) | ZA982335B ( ) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9820405D0 (en) * | 1998-09-18 | 1998-11-11 | Smithkline Beecham Plc | Process |
| KR20020038567A (ko) * | 1999-03-19 | 2002-05-23 | 독터. 호르스트 하스칼, 잉에 린스 | 골관절염의 치료방법 |
| US6331550B1 (en) | 1999-06-29 | 2001-12-18 | Smithkline Beecham Corporation | Methods of use of quinolone compounds against anaerobic pathogenic bacteria |
| US6262071B1 (en) | 1999-06-29 | 2001-07-17 | Smithkline Beecham Corporation | Methods of use of antimicrobial compounds against pathogenic amycoplasma bacteria |
| CA2282066C (en) | 1999-06-29 | 2010-09-07 | Smithkline Beecham Corporation | Methods of use of quinolone compounds against atypical upper respiratory pathogenic bacteria |
| US6803376B1 (en) | 1999-06-29 | 2004-10-12 | Smithkline Beecham Corporation | Method of use of quinolone compounds against pneumococcal and haemophilus bacteria |
| GB9920917D0 (en) | 1999-09-03 | 1999-11-10 | Sb Pharmco Inc | Novel process |
| GB9920919D0 (en) * | 1999-09-03 | 1999-11-10 | Sb Pharmco Inc | Novel compound |
| WO2001021176A1 (en) * | 1999-09-22 | 2001-03-29 | Smithkline Beecham Corporation | Methods of use of fluoroquinolone compounds against bacteria |
| GR1003520B (el) * | 1999-09-22 | 2001-01-22 | Smithkline Beecham Plc | Μεθοδος χρησης ενωσεων φλουοροκινολονης εναντια σε νοσοκομειακα αρνητικα κατα gramμ παθογενων βακτηριδιων |
| JP2001097891A (ja) * | 1999-09-24 | 2001-04-10 | Smithkline Beecham Corp | 呼吸器系病原菌に対するフルオロキノロン化合物の使用法 |
| JP2001097863A (ja) * | 1999-09-24 | 2001-04-10 | Smithkline Beecham Corp | 嫌気性病原菌に対するフルオロキノロン化合物の使用法 |
| JP2001097864A (ja) * | 1999-09-24 | 2001-04-10 | Smithkline Beecham Corp | 呼吸管および尿路病原性細菌に対するフルオロキノリン化合物の使用方法 |
| GR1003521B (el) * | 1999-09-23 | 2001-01-22 | Smithkline Beecham Plc | Μεθοδοι χρησεως ενωσεων φλουοροκινολονης εναντια κατα gram θετικων παθογονων βακτηριδιων |
| KR20010091379A (ko) * | 2000-03-15 | 2001-10-23 | 성재갑 | 7-(4-아미노메틸-3-옥심)피롤리딘 치환체를 갖는 퀴놀린카르복실산 유도체의 신규 제조방법 |
| SI1412078T1 (sl) | 2001-08-02 | 2009-04-30 | Lg Life Sciences Ltd Lg Twin T | Postopki za pripravo amino-zaščitenih derivatov 4-aminometilen-pirolidin-3-ona, gemifloksacina ali njegove soli |
| DK1458391T3 (da) * | 2001-11-30 | 2008-01-07 | Lg Life Sciences Ltd | Fremgangsmåde til at behandle bakterielle infektioner ved anvendelse af gemifloxacin eller et salt deraf og et beta-lactamantibiotikum |
| KR100517638B1 (ko) | 2002-04-08 | 2005-09-28 | 주식회사 엘지생명과학 | 게미플록사신 산염의 새로운 제조방법 |
| AR043880A1 (es) * | 2003-04-22 | 2005-08-17 | Solvay Pharm Gmbh | Mesilato acido de 4-(4.trans-hidroxiciclohexil) amino-2-fenil-7h-pirrolo (2,3-d) pirimidina y sus formas polimorfas |
| US7834027B2 (en) | 2005-06-15 | 2010-11-16 | Hetero Drugs Limited | Gemifloxacin process and polymorphs |
| CA2644661C (en) * | 2006-03-07 | 2013-12-31 | Wockhardt Ltd | Prodrugs of benzoquinolizine-2-carboxylic acid |
| WO2010001408A2 (en) * | 2008-06-06 | 2010-01-07 | Matrix Laboratories Ltd. | Novel polymorphic forms of gemifloxacin mesylate |
| WO2010146594A1 (en) * | 2009-06-16 | 2010-12-23 | Hetero Research Foundation | Novel polymorphs of gemifloxacin mesylate |
| EP2491921A1 (en) | 2011-02-25 | 2012-08-29 | Deva Holding Anonim Sirketi | Conservation of anhydrous form of gemifloxacin |
| DK2820016T3 (da) * | 2012-02-27 | 2017-11-13 | Bristol Myers Squibb Co | N-(5s,6s,9r)-5-amino-6-(2,3-difluorphenyl)-6,7,8,9-tetrahydro-5h- cyclohepta[b]pyridin-9-yl-4-(2-oxo-2,3-dihydro-1h-imidazo[4,5-b]pyridin-1- yl)piperidin-1-carboxylat, hemisulfatsalt |
| CZ2016104A3 (cs) * | 2016-02-24 | 2017-09-06 | Zentiva, K.S. | Krystalické modifikace solí methyl (3Z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}fenyl)amino](fenyl)methyliden}-2-oxo-2,3-dihydro-1H-indol-6-karboxylátu a způsoby jejich přípravy |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR223983A1 (es) | 1978-08-25 | 1981-10-15 | Dainippon Pharmaceutical Co | Un procedimiento para-preparar derivados de acido 6-halogeno-4-oxo-7-(1-piperazinil)-1,8-naftiridin-3-carboxilico |
| HU188181B (en) | 1981-06-11 | 1986-03-28 | Warner-Lambert Co,Us | Process for producing salts of naphtiridine and quinoline compounds of antimicrobial activity |
| IN162769B ( ) | 1984-11-13 | 1988-07-09 | Kyorin Seiyaku Kk | |
| NZ222047A (en) | 1986-10-08 | 1991-01-29 | Bristol Myers Co | Quinoline - or naphthyridine - carboxylic acid anti-bacterial agents |
| JPH01100165A (ja) | 1987-10-13 | 1989-04-18 | Shionogi & Co Ltd | オキシムまたはヒドロキシアミン誘導体系抗菌剤 |
| US4920120A (en) | 1988-01-25 | 1990-04-24 | Warner-Lambert Company | Antibacterial agents |
| US4931446A (en) | 1988-03-23 | 1990-06-05 | Abbott Laboratories | Antimicrobial for in-vitro diagnostic kits |
| US5286723A (en) | 1988-08-31 | 1994-02-15 | Daiichi Seiyaku Co., Ltd. | Spiro compound |
| CA1336090C (en) | 1988-08-31 | 1995-06-27 | Isao Hayakawa | Spiro-substituted cyclic amines of quinolone derivatives |
| RU2049777C1 (ru) | 1989-08-16 | 1995-12-10 | Пфайзер Инк. | Азабицикло-хинолон-карбоновые кислоты или их фармацевтически приемлемые кислотно-аддитивные соли и промежуточные продукты для их получения |
| EP0541086A1 (en) | 1991-11-08 | 1993-05-12 | Kaken Pharmaceutical Co., Ltd. | Antibacterial 6-fluoro-quinolones having an oxime group on the substituent in position 7 |
| WO1993025545A1 (en) | 1992-06-09 | 1993-12-23 | Korea Research Institute Of Chemical Technology | Novel quinoline derivatives and processes for preparing the same |
| US5776944A (en) | 1994-06-16 | 1998-07-07 | Lg Chemical Ltd. | 7-(4-aminomethyl-3-methyloxyiminopyrroplidin-1-yl)-1-cyclopropyl-6-flu oro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid and the process for the preparation thereof |
| DE69509442T2 (de) | 1994-06-16 | 1999-09-02 | Lg Chemical Ltd | Chinolincarbonsäurederivate mit 7-(4-Amino-methyl-3-oxim)-pyrrolidin-Substituenten und Verfahren zu ihrer Herstellung |
| EP0787720B1 (en) | 1994-10-20 | 2003-07-16 | Wakunaga Seiyaku Kabushiki Kaisha | Pyridonecarboxylate derivative or salt thereof and antibacterial containing the same as active ingredient |
| KR100499366B1 (ko) | 1995-01-30 | 2005-09-08 | 와쿠나가 세이야쿠 가부시키 가이샤 | 신규피리돈카르복실산유도체또는그염및그물질을유효성분으로하는항균제 |
| DK0789697T3 (da) | 1995-06-06 | 1998-10-19 | Pfizer | Krystalform af vandfrit 7-([1alfa, 5alfa, 6alfa,]-6-amino-3-azabicyclo[3.1.0]hex-3-yl)-6-fluor-1-(2,4-difluorphenyl)-1,4-d |
| US20020032216A1 (en) * | 1997-03-21 | 2002-03-14 | Lg Chemical Ltd. | Salt of naphthyridine carboxylic acid derivative |
| KR100286874B1 (ko) | 1998-03-04 | 2001-04-16 | 성재갑 | 보호된 4-아미노메틸-피롤리딘-3-온의 제조방법 |
| GB9820405D0 (en) | 1998-09-18 | 1998-11-11 | Smithkline Beecham Plc | Process |
-
1998
- 1998-03-17 MA MA25001A patent/MA24500A1/fr unknown
- 1998-03-18 DZ DZ980058A patent/DZ2448A1/xx active
- 1998-03-19 ZA ZA9802335A patent/ZA982335B/xx unknown
- 1998-03-20 UA UA99095186A patent/UA56218C2/uk unknown
- 1998-03-20 PT PT98908300T patent/PT981527E/pt unknown
- 1998-03-20 AR ARP980101268A patent/AR012125A1/es active IP Right Grant
- 1998-03-20 KR KR1019980009717A patent/KR100266499B1/ko active IP Right Grant
- 1998-03-20 CN CN98803576A patent/CN1131229C/zh not_active Expired - Lifetime
- 1998-03-20 PE PE1998000202A patent/PE67999A1/es not_active Application Discontinuation
- 1998-03-20 DK DK98908300T patent/DK0981527T3/da active
- 1998-03-20 SI SI9830418T patent/SI0981527T1/xx unknown
- 1998-03-20 ES ES98908300T patent/ES2198697T3/es not_active Expired - Lifetime
- 1998-03-20 DE DE69821147T patent/DE69821147T2/de not_active Expired - Lifetime
- 1998-03-20 JP JP54550098A patent/JP3759962B2/ja not_active Expired - Lifetime
- 1998-03-20 DE DE69814378T patent/DE69814378T2/de not_active Expired - Lifetime
- 1998-03-20 HU HU0600401A patent/HU227536B1/hu unknown
- 1998-03-20 AT AT98908300T patent/ATE239724T1/de active
- 1998-03-20 BR BR9808290-6A patent/BR9808290A/pt not_active Application Discontinuation
- 1998-03-20 CZ CZ19993282A patent/CZ288673B6/cs not_active IP Right Cessation
- 1998-03-20 DK DK01203507T patent/DK1179533T3/da active
- 1998-03-20 AU AU66366/98A patent/AU726634B2/en not_active Expired
- 1998-03-20 ID IDW991044A patent/ID22681A/id unknown
- 1998-03-20 PT PT01203507T patent/PT1179533E/pt unknown
- 1998-03-20 AT AT01203507T patent/ATE257836T1/de active
- 1998-03-20 EP EP98908300A patent/EP0981527B1/en not_active Expired - Lifetime
- 1998-03-20 AP APAP/P/1999/001649A patent/AP1331A/en active
- 1998-03-20 SK SK1236-99A patent/SK284107B6/sk not_active IP Right Cessation
- 1998-03-20 EA EA199900855A patent/EA001674B1/ru not_active IP Right Cessation
- 1998-03-20 EP EP01203507A patent/EP1179533B1/en not_active Expired - Lifetime
- 1998-03-20 NZ NZ337748A patent/NZ337748A/xx not_active IP Right Cessation
- 1998-03-20 ES ES01203507T patent/ES2213669T3/es not_active Expired - Lifetime
- 1998-03-20 CA CA002283671A patent/CA2283671C/en not_active Expired - Lifetime
- 1998-03-20 HU HU0000728A patent/HU225412B1/hu unknown
- 1998-03-20 TR TR1999/02313T patent/TR199902313T2/xx unknown
- 1998-03-20 WO PCT/KR1998/000051 patent/WO1998042705A1/en active IP Right Grant
- 1998-03-20 IL IL13181298A patent/IL131812A0/xx active IP Right Grant
- 1998-03-20 PL PL335812A patent/PL191815B1/pl unknown
- 1998-03-20 SI SI9830595T patent/SI1179533T1/ unknown
- 1998-03-20 IL IL131812A patent/IL131812A/en not_active IP Right Cessation
- 1998-03-21 MY MYPI98001236A patent/MY137653A/en unknown
- 1998-03-23 IN IN727DE1998 patent/IN188178B/en unknown
- 1998-03-25 SA SA98181055A patent/SA98181055B1/ar unknown
-
1999
- 1999-09-14 IS IS5181A patent/IS2093B/is unknown
- 1999-09-20 OA OA9900213A patent/OA11161A/fr unknown
- 1999-09-21 NO NO19994595A patent/NO312515B1/no not_active IP Right Cessation
- 1999-09-21 BG BG103750A patent/BG63972B1/bg unknown
-
2000
- 2000-08-30 HK HK00105435A patent/HK1026698A1/xx not_active IP Right Cessation
- 2000-10-03 CZ CZ20003641A patent/CZ288715B6/cs not_active IP Right Cessation
-
2003
- 2003-05-07 JP JP2003128650A patent/JP4781614B2/ja not_active Expired - Lifetime
-
2005
- 2005-07-21 IS IS7952A patent/IS2095B/is unknown
-
2006
- 2006-12-07 US US11/635,069 patent/US7700617B2/en not_active Expired - Fee Related
-
2008
- 2008-10-14 JP JP2008265345A patent/JP2009051851A/ja not_active Withdrawn
-
2009
- 2009-01-09 US US12/318,845 patent/US20090182006A1/en not_active Abandoned
-
2010
- 2010-06-02 US US12/791,957 patent/US20100240694A1/en not_active Abandoned
-
2011
- 2011-04-11 US US13/083,685 patent/US20110312987A1/en not_active Abandoned
-
2012
- 2012-06-26 US US13/533,383 patent/US20130065917A1/en not_active Abandoned
-
2013
- 2013-10-25 US US14/063,117 patent/US20140187576A1/en not_active Abandoned
-
2015
- 2015-02-13 US US14/621,689 patent/US20150291585A1/en not_active Abandoned
-
2016
- 2016-01-15 US US14/996,765 patent/US20160264569A1/en not_active Abandoned
-
2017
- 2017-01-20 US US15/411,030 patent/US20170253588A1/en not_active Abandoned
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