SI1140941T1 - Nitrogen containing heterobicycles as factor xa inhibitors - Google Patents

Nitrogen containing heterobicycles as factor xa inhibitors

Info

Publication number
SI1140941T1
SI1140941T1 SI9930721T SI9930721T SI1140941T1 SI 1140941 T1 SI1140941 T1 SI 1140941T1 SI 9930721 T SI9930721 T SI 9930721T SI 9930721 T SI9930721 T SI 9930721T SI 1140941 T1 SI1140941 T1 SI 1140941T1
Authority
SI
Slovenia
Prior art keywords
inhibitors
factor
nitrogen containing
containing heterobicycles
heterobicycles
Prior art date
Application number
SI9930721T
Other languages
English (en)
Slovenian (sl)
Inventor
John M. Fevig
Joseph Cacciola
Charles G. Clark
Patrick Yuk Sun Lam
Donald J. P. Pinto
James R. Pruitt
Karen A. Rossi
Original Assignee
Bristol-Myers Squibb Pharma Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26811284&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1140941(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol-Myers Squibb Pharma Company filed Critical Bristol-Myers Squibb Pharma Company
Publication of SI1140941T1 publication Critical patent/SI1140941T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SI9930721T 1998-12-23 1999-12-17 Nitrogen containing heterobicycles as factor xa inhibitors SI1140941T1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11362898P 1998-12-23 1998-12-23
US12763399P 1999-04-02 1999-04-02
EP99967444A EP1140941B1 (de) 1998-12-23 1999-12-17 Stickstoffhaltige heterobicyclen als faktor-xa-hemmer
PCT/US1999/030316 WO2000039131A1 (en) 1998-12-23 1999-12-17 Nitrogen containing heterobicycles as factor xa inhibitors

Publications (1)

Publication Number Publication Date
SI1140941T1 true SI1140941T1 (en) 2005-04-30

Family

ID=26811284

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9930721T SI1140941T1 (en) 1998-12-23 1999-12-17 Nitrogen containing heterobicycles as factor xa inhibitors

Country Status (26)

Country Link
US (2) US6413980B1 (de)
EP (1) EP1140941B1 (de)
JP (1) JP2002533465A (de)
KR (1) KR100628407B1 (de)
CN (1) CN100340559C (de)
AR (1) AR024242A1 (de)
AT (1) ATE280171T1 (de)
AU (1) AU759711B2 (de)
BR (1) BR9917080A (de)
CA (1) CA2349330C (de)
DE (1) DE69921358T2 (de)
DK (1) DK1140941T3 (de)
EA (1) EA004515B1 (de)
ES (1) ES2232202T3 (de)
HK (1) HK1052508B (de)
HR (1) HRP990396A2 (de)
IL (2) IL142959A0 (de)
MX (1) MXPA01006502A (de)
MY (1) MY138239A (de)
NO (1) NO319816B1 (de)
NZ (1) NZ511674A (de)
PT (1) PT1140941E (de)
SI (1) SI1140941T1 (de)
TW (1) TWI225862B (de)
WO (1) WO2000039131A1 (de)
ZA (1) ZA200103795B (de)

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US20040077605A1 (en) * 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
EP1854798A3 (de) 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Kondensierte heterozyklische Succinimid-Verbindungen und Analoga daraus, Modulatoren der nuklearen Hormonrezeptorfunktion
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US6960595B2 (en) * 2001-03-23 2005-11-01 Bristol-Myers Squibb Pharma Company 5-6 to 5-7 Heterobicycles as factor Xa inhibitors
EP1379244A4 (de) 2001-04-18 2006-03-15 Bristol Myers Squibb Co 1,4,5,6-tetrahydropyrazolo- 3,4-c]-pyridin-7-one als faktor xa hemmer
CA2444571A1 (en) * 2001-04-18 2002-10-31 Bristol-Myers Squibb Company 1, 4, 5, 6-tetrahydropyrazolo-¬3, 4-c|-pyridin-7-ones as factor xa inhi bitors
EP1414449A4 (de) * 2001-05-22 2005-04-06 Bristol Myers Squibb Co Bizyklische faktor-xa-hemmer
ES2329881T3 (es) 2001-09-21 2009-12-02 Bristol-Myers Squibb Company Compuestos que contienen lactama y derivados de los mismos como inhibidores del factor xa.
TWI331526B (en) 2001-09-21 2010-10-11 Bristol Myers Squibb Pharma Co Lactam-containing compounds and derivatives thereof as factor xa inhibitors
TW200302225A (en) 2001-12-04 2003-08-01 Bristol Myers Squibb Co Substituted amino methyl factor Xa inhibitors
AU2002350217A1 (en) * 2001-12-04 2003-06-17 Bristol-Myers Squibb Company Glycinamides as factor xa inhibitors
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JP4434740B2 (ja) * 2001-12-19 2010-03-17 ブリストル−マイヤーズ スクイブ カンパニー 核ホルモン受容体機能の調節剤である、縮合ヘテロ環化合物およびその類似体
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CN105085515B (zh) * 2014-05-22 2019-02-01 华北制药股份有限公司 作为凝血因子Xa抑制剂的酰肼类化合物
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KR102128509B1 (ko) * 2018-12-19 2020-07-01 한국과학기술연구원 말단 아민기에 아릴 또는 헤테로아릴기가 치환된 신규한 히드라존 유도체 및 이의 용도
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Also Published As

Publication number Publication date
HRP990396A2 (en) 2000-08-31
EA004515B1 (ru) 2004-04-29
NO20013072D0 (no) 2001-06-20
HK1052508A1 (en) 2003-09-19
CA2349330C (en) 2009-09-29
NZ511674A (en) 2003-11-28
US6413980B1 (en) 2002-07-02
WO2000039131A1 (en) 2000-07-06
AU759711B2 (en) 2003-04-17
CA2349330A1 (en) 2000-07-06
AU2371700A (en) 2000-07-31
PT1140941E (pt) 2005-02-28
ATE280171T1 (de) 2004-11-15
DK1140941T3 (da) 2005-02-14
TWI225862B (en) 2005-01-01
IL142959A (en) 2010-05-31
MY138239A (en) 2009-05-29
AR024242A1 (es) 2002-09-25
BR9917080A (pt) 2002-03-12
US20030004167A1 (en) 2003-01-02
CN100340559C (zh) 2007-10-03
NO319816B1 (no) 2005-09-19
MXPA01006502A (es) 2002-04-08
HK1052508B (zh) 2008-08-01
EP1140941A1 (de) 2001-10-10
JP2002533465A (ja) 2002-10-08
IL142959A0 (en) 2002-04-21
CN1391575A (zh) 2003-01-15
NO20013072L (no) 2001-06-20
EP1140941B1 (de) 2004-10-20
ZA200103795B (en) 2002-08-12
DE69921358D1 (de) 2004-11-25
ES2232202T3 (es) 2005-05-16
EA200100688A1 (ru) 2001-12-24
KR20010092754A (ko) 2001-10-26
DE69921358T2 (de) 2006-03-09
KR100628407B1 (ko) 2006-09-26
US6673810B2 (en) 2004-01-06

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