SI1068194T1 - Pde iv inhibiting pyridine derivatives - Google Patents

Pde iv inhibiting pyridine derivatives

Info

Publication number
SI1068194T1
SI1068194T1 SI9930470T SI9930470T SI1068194T1 SI 1068194 T1 SI1068194 T1 SI 1068194T1 SI 9930470 T SI9930470 T SI 9930470T SI 9930470 T SI9930470 T SI 9930470T SI 1068194 T1 SI1068194 T1 SI 1068194T1
Authority
SI
Slovenia
Prior art keywords
pde
pyridine derivatives
inhibiting
inhibiting pyridine
derivatives
Prior art date
Application number
SI9930470T
Other languages
English (en)
Slovenian (sl)
Inventor
Eddy Jean Edgard Freyne
Gaston Stanislas Marcella Diels
Janssen-Cilag S.A. Matesanz-Ballesteros
Adolfo Janssen-Cilag S.A. DIAZ-MARTINEZ
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of SI1068194T1 publication Critical patent/SI1068194T1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/14Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SI9930470T 1998-04-01 1999-03-24 Pde iv inhibiting pyridine derivatives SI1068194T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98201020 1998-04-01
EP99913302A EP1068194B1 (en) 1998-04-01 1999-03-24 Pde iv inhibiting pyridine derivatives
PCT/EP1999/002045 WO1999050262A1 (en) 1998-04-01 1999-03-24 Pde iv inhibiting pyridine derivatives

Publications (1)

Publication Number Publication Date
SI1068194T1 true SI1068194T1 (en) 2004-04-30

Family

ID=8233543

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9930470T SI1068194T1 (en) 1998-04-01 1999-03-24 Pde iv inhibiting pyridine derivatives

Country Status (34)

Country Link
US (1) US6656959B1 (xx)
EP (1) EP1068194B1 (xx)
JP (1) JP4778612B2 (xx)
KR (1) KR100596664B1 (xx)
CN (1) CN1172930C (xx)
AR (1) AR014972A1 (xx)
AT (1) ATE253569T1 (xx)
AU (1) AU760771B2 (xx)
BG (1) BG64705B1 (xx)
BR (1) BR9909326A (xx)
CA (1) CA2326045C (xx)
CZ (1) CZ298747B6 (xx)
DE (1) DE69912590T2 (xx)
DK (1) DK1068194T3 (xx)
EA (1) EA004207B1 (xx)
EE (1) EE04718B1 (xx)
ES (1) ES2211061T3 (xx)
HK (1) HK1033579A1 (xx)
HR (1) HRP20000619B1 (xx)
HU (1) HU229412B1 (xx)
ID (1) ID27207A (xx)
IL (2) IL138745A0 (xx)
MY (1) MY124696A (xx)
NO (1) NO319531B1 (xx)
NZ (1) NZ507022A (xx)
PL (1) PL196026B1 (xx)
PT (1) PT1068194E (xx)
SI (1) SI1068194T1 (xx)
SK (1) SK284468B6 (xx)
TR (1) TR200002801T2 (xx)
TW (1) TWI242558B (xx)
UA (1) UA66842C2 (xx)
WO (1) WO1999050262A1 (xx)
ZA (1) ZA200006190B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY123585A (en) 2000-03-23 2006-05-31 Merck Canada Inc Tri-aryl-substituted-ethane pde4 inhibitors.
US6639077B2 (en) 2000-03-23 2003-10-28 Merck Frosst Canada & Co. Tri-aryl-substituted-ethane PDE4 inhibitors
DE10130397A1 (de) * 2001-06-23 2003-01-09 Bayer Cropscience Gmbh Herbizide substituierte Pyridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Herbzide und Pflanzenwachstumsregulatoren
DE10318610A1 (de) * 2003-04-24 2004-11-11 Elbion Ag 7-Azaindole und deren Verwendung als Therapeutika
JP4185154B2 (ja) 2004-04-30 2008-11-26 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー 中枢神経系障害治療用の置換モルホリン化合物
US7863446B2 (en) 2006-01-19 2011-01-04 Orchid Research Laboratories Limited Heterocycles
WO2007085357A1 (en) 2006-01-30 2007-08-02 Euro-Celtique S.A. Cyclourea compounds as calcium channel blockers
BRPI0717596B8 (pt) 2006-10-18 2021-05-25 Pfizer Prod Inc compostos de éter biarílico uréia, seu uso e composição farmacêutica que os compreende
BRPI0912029A2 (pt) 2008-02-01 2020-06-30 Orchid Research Laboratories Limited novos heterociclos
JOP20190060A1 (ar) 2016-09-26 2019-03-26 Chugai Pharmaceutical Co Ltd مشتق بيرازولو بيريدين له تأثير مساعد لمستقبل glp-1

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3876657A (en) * 1971-06-03 1975-04-08 Ashland Oil Inc Preparation of 1-substituted-2-imidazolidinones
US4600430A (en) 1985-02-22 1986-07-15 Eli Lilly And Company Pyridinylimidazolidinone compounds
ZA945609B (en) * 1993-07-28 1995-05-12 Rhone Poulenc Rorer Ltd [Di(ether or thioether)heteroaryl or fluoro substituted aryl] compounds
GB9401460D0 (en) * 1994-01-26 1994-03-23 Rhone Poulenc Rorer Ltd Compositions of matter
AU3272195A (en) * 1994-08-03 1996-03-04 Gics & Vermee, L.P. Ovenable food package
TW332201B (en) * 1995-04-06 1998-05-21 Janssen Pharmaceutica Nv 1,3-Dihydro-1-(phenylalkyl)-2H-imidazol-2-one derivatives
TW424087B (en) * 1995-04-06 2001-03-01 Janssen Pharmaceutica Nv 1,3-dihydro-1-(phenylalkenyl)-2H-imidazol-2-one derivatives
TW375612B (en) * 1995-04-06 1999-12-01 Janssen Pharmaceutica Nv 1,3-dihydro-2H-imidazol-2-one derivatives for the treatment of disease states related to an abnormal enzymatic or catalytic activity of phosphodiesterase type IV, preparation thereof and pharmaceutical composition containing the same
WO1997003967A1 (en) * 1995-07-22 1997-02-06 Rhone-Poulenc Rorer Limited Substituted aromatic compounds and their pharmaceutical use
IL125034A0 (en) * 1995-12-29 1999-01-26 Smithkline Beecham Corp Vitronectin receptor antagonists
UA62939C2 (uk) * 1996-10-02 2004-01-15 Янссен Фармацевтика Н.В. Похідне 2-ціаноіміноімідазолу, фармацевтична композиція та спосіб одержання сполуки

Also Published As

Publication number Publication date
UA66842C2 (uk) 2004-06-15
KR20010040681A (ko) 2001-05-15
HU229412B1 (en) 2013-12-30
PL343194A1 (en) 2001-07-30
CA2326045C (en) 2008-12-09
BG64705B1 (bg) 2005-12-30
PL196026B1 (pl) 2007-11-30
US6656959B1 (en) 2003-12-02
CZ298747B6 (cs) 2008-01-16
TR200002801T2 (tr) 2000-12-21
NO319531B1 (no) 2005-08-29
DE69912590D1 (de) 2003-12-11
NZ507022A (en) 2002-06-28
EP1068194A1 (en) 2001-01-17
EE04718B1 (et) 2006-10-16
BG104718A (en) 2001-04-30
HRP20000619A2 (en) 2001-10-31
DE69912590T2 (de) 2004-09-16
DK1068194T3 (da) 2004-03-15
CN1172930C (zh) 2004-10-27
EP1068194B1 (en) 2003-11-05
NO20004906D0 (no) 2000-09-29
CN1295571A (zh) 2001-05-16
SK13872000A3 (sk) 2001-11-06
PT1068194E (pt) 2004-03-31
ZA200006190B (en) 2001-10-31
HRP20000619B1 (en) 2004-06-30
EA004207B1 (ru) 2004-02-26
HUP0101239A3 (en) 2002-09-30
ES2211061T3 (es) 2004-07-01
AU3147499A (en) 1999-10-18
JP4778612B2 (ja) 2011-09-21
KR100596664B1 (ko) 2006-07-06
SK284468B6 (sk) 2005-04-01
JP2002509927A (ja) 2002-04-02
ID27207A (id) 2001-03-08
ATE253569T1 (de) 2003-11-15
TWI242558B (en) 2005-11-01
NO20004906L (no) 2000-11-28
WO1999050262A1 (en) 1999-10-07
HUP0101239A2 (hu) 2002-05-29
AR014972A1 (es) 2001-04-11
BR9909326A (pt) 2000-12-12
AU760771B2 (en) 2003-05-22
CA2326045A1 (en) 1999-10-07
IL138745A (en) 2007-06-17
HK1033579A1 (en) 2001-09-07
CZ20003338A3 (cs) 2001-02-14
MY124696A (en) 2006-06-30
IL138745A0 (en) 2001-10-31
EE200000569A (et) 2002-04-15
EA200001009A1 (ru) 2001-02-26

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