HRP20000619B1 - Pde iv inhibiting pyridine derivatives - Google Patents
Pde iv inhibiting pyridine derivativesInfo
- Publication number
- HRP20000619B1 HRP20000619B1 HR20000619A HRP20000619A HRP20000619B1 HR P20000619 B1 HRP20000619 B1 HR P20000619B1 HR 20000619 A HR20000619 A HR 20000619A HR P20000619 A HRP20000619 A HR P20000619A HR P20000619 B1 HRP20000619 B1 HR P20000619B1
- Authority
- HR
- Croatia
- Prior art keywords
- pde
- pyridine derivatives
- inhibiting
- inhibiting pyridine
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98201020 | 1998-04-01 | ||
| PCT/EP1999/002045 WO1999050262A1 (en) | 1998-04-01 | 1999-03-24 | Pde iv inhibiting pyridine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HRP20000619A2 HRP20000619A2 (en) | 2001-10-31 |
| HRP20000619B1 true HRP20000619B1 (en) | 2004-06-30 |
Family
ID=8233543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20000619A HRP20000619B1 (en) | 1998-04-01 | 2000-09-19 | Pde iv inhibiting pyridine derivatives |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US6656959B1 (xx) |
| EP (1) | EP1068194B1 (xx) |
| JP (1) | JP4778612B2 (xx) |
| KR (1) | KR100596664B1 (xx) |
| CN (1) | CN1172930C (xx) |
| AR (1) | AR014972A1 (xx) |
| AT (1) | ATE253569T1 (xx) |
| AU (1) | AU760771B2 (xx) |
| BG (1) | BG64705B1 (xx) |
| BR (1) | BR9909326A (xx) |
| CA (1) | CA2326045C (xx) |
| CZ (1) | CZ298747B6 (xx) |
| DE (1) | DE69912590T2 (xx) |
| DK (1) | DK1068194T3 (xx) |
| EA (1) | EA004207B1 (xx) |
| EE (1) | EE04718B1 (xx) |
| ES (1) | ES2211061T3 (xx) |
| HK (1) | HK1033579A1 (xx) |
| HR (1) | HRP20000619B1 (xx) |
| HU (1) | HU229412B1 (xx) |
| ID (1) | ID27207A (xx) |
| IL (2) | IL138745A0 (xx) |
| MY (1) | MY124696A (xx) |
| NO (1) | NO319531B1 (xx) |
| NZ (1) | NZ507022A (xx) |
| PL (1) | PL196026B1 (xx) |
| PT (1) | PT1068194E (xx) |
| SI (1) | SI1068194T1 (xx) |
| SK (1) | SK284468B6 (xx) |
| TR (1) | TR200002801T2 (xx) |
| TW (1) | TWI242558B (xx) |
| UA (1) | UA66842C2 (xx) |
| WO (1) | WO1999050262A1 (xx) |
| ZA (1) | ZA200006190B (xx) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6639077B2 (en) | 2000-03-23 | 2003-10-28 | Merck Frosst Canada & Co. | Tri-aryl-substituted-ethane PDE4 inhibitors |
| MY123585A (en) | 2000-03-23 | 2006-05-31 | Merck Canada Inc | Tri-aryl-substituted-ethane pde4 inhibitors. |
| DE10130397A1 (de) * | 2001-06-23 | 2003-01-09 | Bayer Cropscience Gmbh | Herbizide substituierte Pyridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Herbzide und Pflanzenwachstumsregulatoren |
| DE10318610A1 (de) * | 2003-04-24 | 2004-11-11 | Elbion Ag | 7-Azaindole und deren Verwendung als Therapeutika |
| BRPI0510453A (pt) | 2004-04-30 | 2007-10-30 | Warner Lambert Co | composto substituìdos com morfolina para o tratamento de distúrbios do sistema nervoso central |
| US7863446B2 (en) | 2006-01-19 | 2011-01-04 | Orchid Research Laboratories Limited | Heterocycles |
| US8354434B2 (en) | 2006-01-30 | 2013-01-15 | Purdue Pharma L.P. | Cyclourea compounds as calcium channel blockers |
| GEP20125425B (en) | 2006-10-18 | 2012-03-26 | Pfizer Prod Inc | Biaryl ether urea compounds |
| BRPI0912029A2 (pt) | 2008-02-01 | 2020-06-30 | Orchid Research Laboratories Limited | novos heterociclos |
| JOP20190060A1 (ar) | 2016-09-26 | 2019-03-26 | Chugai Pharmaceutical Co Ltd | مشتق بيرازولو بيريدين له تأثير مساعد لمستقبل glp-1 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3876657A (en) * | 1971-06-03 | 1975-04-08 | Ashland Oil Inc | Preparation of 1-substituted-2-imidazolidinones |
| US4600430A (en) | 1985-02-22 | 1986-07-15 | Eli Lilly And Company | Pyridinylimidazolidinone compounds |
| EP0711282B1 (en) * | 1993-07-28 | 2002-06-05 | Aventis Pharma Limited | Compounds as pde iv and tnf inhibitors |
| GB9401460D0 (en) * | 1994-01-26 | 1994-03-23 | Rhone Poulenc Rorer Ltd | Compositions of matter |
| WO1996004186A1 (en) * | 1994-08-03 | 1996-02-15 | Gics & Vermee, L.P. | Ovenable food package |
| TW424087B (en) | 1995-04-06 | 2001-03-01 | Janssen Pharmaceutica Nv | 1,3-dihydro-1-(phenylalkenyl)-2H-imidazol-2-one derivatives |
| TW375612B (en) | 1995-04-06 | 1999-12-01 | Janssen Pharmaceutica Nv | 1,3-dihydro-2H-imidazol-2-one derivatives for the treatment of disease states related to an abnormal enzymatic or catalytic activity of phosphodiesterase type IV, preparation thereof and pharmaceutical composition containing the same |
| TW332201B (en) * | 1995-04-06 | 1998-05-21 | Janssen Pharmaceutica Nv | 1,3-Dihydro-1-(phenylalkyl)-2H-imidazol-2-one derivatives |
| WO1997003967A1 (en) * | 1995-07-22 | 1997-02-06 | Rhone-Poulenc Rorer Limited | Substituted aromatic compounds and their pharmaceutical use |
| KR19990076876A (ko) * | 1995-12-29 | 1999-10-25 | 스티븐 베네티아너 | 비트로넥틴 수용체 길항제 |
| ATE236884T1 (de) * | 1996-10-02 | 2003-04-15 | Janssen Pharmaceutica Nv | Pde-iv hemmende 2-cyanoiminoimidazol-derivate |
-
1999
- 1999-03-24 TR TR2000/02801T patent/TR200002801T2/xx unknown
- 1999-03-24 DK DK99913302T patent/DK1068194T3/da active
- 1999-03-24 PT PT99913302T patent/PT1068194E/pt unknown
- 1999-03-24 SK SK1387-2000A patent/SK284468B6/sk not_active IP Right Cessation
- 1999-03-24 EE EEP200000569A patent/EE04718B1/xx unknown
- 1999-03-24 ES ES99913302T patent/ES2211061T3/es not_active Expired - Lifetime
- 1999-03-24 AU AU31474/99A patent/AU760771B2/en not_active Expired
- 1999-03-24 CZ CZ20003338A patent/CZ298747B6/cs not_active IP Right Cessation
- 1999-03-24 CN CNB998047376A patent/CN1172930C/zh not_active Expired - Lifetime
- 1999-03-24 NZ NZ507022A patent/NZ507022A/en not_active IP Right Cessation
- 1999-03-24 UA UA2000105769A patent/UA66842C2/uk unknown
- 1999-03-24 ID IDW20001941A patent/ID27207A/id unknown
- 1999-03-24 HU HU0101239A patent/HU229412B1/hu unknown
- 1999-03-24 EA EA200001009A patent/EA004207B1/ru not_active IP Right Cessation
- 1999-03-24 WO PCT/EP1999/002045 patent/WO1999050262A1/en active IP Right Grant
- 1999-03-24 US US09/647,668 patent/US6656959B1/en not_active Expired - Lifetime
- 1999-03-24 DE DE69912590T patent/DE69912590T2/de not_active Expired - Lifetime
- 1999-03-24 KR KR1020007008557A patent/KR100596664B1/ko not_active IP Right Cessation
- 1999-03-24 BR BR9909326-0A patent/BR9909326A/pt not_active Application Discontinuation
- 1999-03-24 EP EP99913302A patent/EP1068194B1/en not_active Expired - Lifetime
- 1999-03-24 AT AT99913302T patent/ATE253569T1/de active
- 1999-03-24 SI SI9930470T patent/SI1068194T1/xx unknown
- 1999-03-24 PL PL99343194A patent/PL196026B1/pl unknown
- 1999-03-24 CA CA002326045A patent/CA2326045C/en not_active Expired - Lifetime
- 1999-03-24 IL IL13874599A patent/IL138745A0/xx active IP Right Grant
- 1999-03-24 JP JP2000541166A patent/JP4778612B2/ja not_active Expired - Lifetime
- 1999-03-26 MY MYPI99001169A patent/MY124696A/en unknown
- 1999-03-29 TW TW088104881A patent/TWI242558B/zh not_active IP Right Cessation
- 1999-03-31 AR ARP990101489A patent/AR014972A1/es not_active Application Discontinuation
-
2000
- 2000-08-28 BG BG104718A patent/BG64705B1/bg unknown
- 2000-09-19 HR HR20000619A patent/HRP20000619B1/xx not_active IP Right Cessation
- 2000-09-28 IL IL138745A patent/IL138745A/en not_active IP Right Cessation
- 2000-09-29 NO NO20004906A patent/NO319531B1/no not_active IP Right Cessation
- 2000-10-31 ZA ZA200006190A patent/ZA200006190B/en unknown
-
2001
- 2001-05-19 HK HK01103462A patent/HK1033579A1/xx not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1OB | Publication of a patent application | ||
| ARAI | Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application | ||
| B1PR | Patent granted | ||
| ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20180215 Year of fee payment: 20 |
|
| PB20 | Patent expired after termination of 20 years |
Effective date: 20190324 |