US6890546B2
(en)
*
|
1998-09-24 |
2005-05-10 |
Abbott Laboratories |
Medical devices containing rapamycin analogs
|
US7399480B2
(en)
|
1997-09-26 |
2008-07-15 |
Abbott Laboratories |
Methods of administering tetrazole-containing rapamycin analogs with other therapeutic substances using medical devices
|
US7357942B2
(en)
*
|
1997-09-26 |
2008-04-15 |
Abbott Laboratories |
Compositions, systems, and kits for administering zotarolimus and paclitaxel to blood vessel lumens
|
US7960405B2
(en)
|
1998-09-24 |
2011-06-14 |
Abbott Laboratories |
Compounds and methods for treatment and prevention of diseases
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
WO2003063904A2
(en)
*
|
2002-01-29 |
2003-08-07 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw |
Tissue adhesion formation control
|
US20030176455A1
(en)
*
|
2002-03-13 |
2003-09-18 |
Wyeth |
Method of inhibiting cell death
|
JP5227492B2
(ja)
|
2002-05-16 |
2013-07-03 |
ノバルティス アーゲー |
癌におけるedgレセプター結合剤の使用
|
AU2003240714B2
(en)
|
2002-05-27 |
2006-09-28 |
Irm Llc |
Bis-aromatic alkanols
|
CN100349627C
(zh)
*
|
2002-09-06 |
2007-11-21 |
艾博特公司 |
含有水合抑制剂的医疗装置及其制备方法
|
RU2391094C2
(ru)
|
2002-09-24 |
2010-06-10 |
Новартис Аг |
Применение агониста рецептора s1p и способ лечения, облегчения или задержки прогрессирования неврита зрительного нерва или демиелинизационных заболеваний
|
JP4944613B2
(ja)
|
2003-05-19 |
2012-06-06 |
アイアールエム・リミテッド・ライアビリティ・カンパニー |
免疫抑制化合物および組成物
|
MY150088A
(en)
|
2003-05-19 |
2013-11-29 |
Irm Llc |
Immunosuppressant compounds and compositions
|
CA2571710A1
(en)
|
2004-06-24 |
2006-11-02 |
Nicholas Valiante |
Small molecule immunopotentiators and assays for their detection
|
MX2007005153A
(es)
|
2004-10-28 |
2007-06-26 |
Wyeth Corp |
Uso de un inhibidor del mtor en el tratamiento de leiomioma del utero.
|
GB0504544D0
(en)
|
2005-03-04 |
2005-04-13 |
Novartis Ag |
Organic compounds
|
WO2007011708A2
(en)
|
2005-07-15 |
2007-01-25 |
Micell Technologies, Inc. |
Stent with polymer coating containing amorphous rapamycin
|
KR101406415B1
(ko)
|
2005-07-15 |
2014-06-19 |
미셀 테크놀로지즈, 인코포레이티드 |
제어된 형태의 약물 분말을 함유하는 중합체 코팅
|
PL1912675T3
(pl)
|
2005-07-25 |
2014-10-31 |
Emergent Product Dev Seattle |
Zmniejszanie liczby komórek B za pomocą cząsteczek wiążących swoistych dla antygenów CD37 i CD20
|
JP5164167B2
(ja)
|
2005-08-30 |
2013-03-13 |
ユニバーシティー オブ マイアミ |
免疫調節性腫瘍壊死因子受容体25(tnfr25)のアゴニスト、アンタゴニスト及び免疫毒素
|
JP2009514870A
(ja)
|
2005-11-04 |
2009-04-09 |
ワイス |
mTORインヒビター、ハーセプチン、および/またはHKI−272の抗悪性腫瘍性組み合わせ
|
US7700614B2
(en)
*
|
2005-12-14 |
2010-04-20 |
Abbott Laboratories |
One pot synthesis of tetrazole derivatives of rapamycin
|
AU2007243268B2
(en)
|
2006-04-26 |
2013-06-13 |
Micell Technologies, Inc. |
Coatings containing multiple drugs
|
US7820812B2
(en)
|
2006-07-25 |
2010-10-26 |
Abbott Laboratories |
Methods of manufacturing crystalline forms of rapamycin analogs
|
US7812032B2
(en)
|
2006-07-25 |
2010-10-12 |
Abbott Laboratories |
Crystalline forms of rapamycin analogs
|
CA2658896A1
(en)
|
2006-07-25 |
2008-01-31 |
Abbott Laboratories |
Crystalline forms of rapamycin analogs
|
US11426494B2
(en)
|
2007-01-08 |
2022-08-30 |
MT Acquisition Holdings LLC |
Stents having biodegradable layers
|
CN101711137B
(zh)
|
2007-01-08 |
2014-10-22 |
米歇尔技术公司 |
具有可生物降解层的支架
|
TW200901989A
(en)
|
2007-04-10 |
2009-01-16 |
Wyeth Corp |
Anti-tumor activity of CCI-779 in papillary renal cell cancer
|
US8685995B2
(en)
|
2008-03-21 |
2014-04-01 |
The University Of Chicago |
Treatment with opioid antagonists and mTOR inhibitors
|
CN102099377A
(zh)
|
2008-04-11 |
2011-06-15 |
新兴产品开发西雅图有限公司 |
Cd37免疫治疗剂及其与双功能化学治疗剂的联合
|
MX2010011485A
(es)
|
2008-04-17 |
2011-03-01 |
Micell Technologies Inc |
Stents que contienen capas bioadsorbibles.
|
CN104800196A
(zh)
|
2008-06-20 |
2015-07-29 |
诺华股份有限公司 |
用于治疗多发性硬化的儿科组合物
|
EP2313122B1
(de)
|
2008-07-17 |
2019-03-06 |
Micell Technologies, Inc. |
Medizinische wirkstofffreisetzungsvorrichtung
|
US9510856B2
(en)
|
2008-07-17 |
2016-12-06 |
Micell Technologies, Inc. |
Drug delivery medical device
|
RU2011129230A
(ru)
|
2008-12-18 |
2013-01-27 |
Новартис Аг |
Новая полиморфная форма 1-[4-[1-(4-циклогексил-3-трифторметилбензилоксиимино)этил]-2-этилбензил]азетидин-3-карбоновой кислоты
|
CN103204794A
(zh)
|
2008-12-18 |
2013-07-17 |
诺瓦提斯公司 |
新的盐
|
KR20110096584A
(ko)
|
2008-12-18 |
2011-08-30 |
노파르티스 아게 |
1-[4-[1-(4-시클로헥실-3-트리플루오로메틸-벤질옥시이미노)-에틸]-2-에틸-벤질]-아제티딘-3-카르복실산의 헤미푸마레이트 염
|
US9981072B2
(en)
|
2009-04-01 |
2018-05-29 |
Micell Technologies, Inc. |
Coated stents
|
EP2419058B1
(de)
|
2009-04-17 |
2018-02-28 |
Micell Technologies, Inc. |
Stents mit gesteuerter elution
|
EP2462165B1
(de)
|
2009-08-03 |
2016-05-11 |
University of Miami |
Verfahren zur in-vivo-expansion regulatorischer t-zellen
|
EP2762142A1
(de)
|
2009-10-30 |
2014-08-06 |
ARIAD Pharmaceuticals, Inc. |
Zusammensetzungen zur Behandlung von Krebs
|
WO2011097103A1
(en)
|
2010-02-02 |
2011-08-11 |
Micell Technologies, Inc. |
Stent and stent delivery system with improved deliverability
|
MX2012008874A
(es)
|
2010-02-11 |
2012-08-31 |
Bristol Myers Squibb Co |
Macrociclos como inhibidores del factor de coagulacion (fxia).
|
US10232092B2
(en)
|
2010-04-22 |
2019-03-19 |
Micell Technologies, Inc. |
Stents and other devices having extracellular matrix coating
|
WO2011134899A1
(en)
|
2010-04-27 |
2011-11-03 |
Roche Glycart Ag |
Combination therapy of an afucosylated cd20 antibody with a mtor inhibitor
|
CN102234288B
(zh)
*
|
2010-05-06 |
2014-07-02 |
上海医药工业研究院 |
唑他莫司的制备方法
|
CA2805631C
(en)
|
2010-07-16 |
2018-07-31 |
Micell Technologies, Inc. |
Drug delivery medical device
|
WO2012112847A1
(en)
|
2011-02-18 |
2012-08-23 |
Novartis Pharma Ag |
mTOR/JAK INHIBITOR COMBINATION THERAPY
|
JP2014519813A
(ja)
|
2011-04-25 |
2014-08-21 |
オーエスアイ・ファーマシューティカルズ,エルエルシー |
癌薬剤発見、診断、および治療におけるemt遺伝子シグネチャーの使用
|
US10117972B2
(en)
|
2011-07-15 |
2018-11-06 |
Micell Technologies, Inc. |
Drug delivery medical device
|
DK2766346T3
(en)
|
2011-10-14 |
2017-07-03 |
Bristol Myers Squibb Co |
SUBSTITUTED TETRAHYDROISOQUINOL COMPOUNDS AS FACTOR XIA INHIBITORS
|
US10188772B2
(en)
|
2011-10-18 |
2019-01-29 |
Micell Technologies, Inc. |
Drug delivery medical device
|
TR201807316T4
(tr)
|
2012-10-12 |
2018-06-21 |
Squibb Bristol Myers Co |
Bir faktör XIa inhibitörünün kristalli formları.
|
EP2906541B1
(de)
|
2012-10-12 |
2017-11-22 |
Bristol-Myers Squibb Company |
Guanidin- und aminsubstituierte tetrahydroisochinoline als factor xia inhibitoren
|
WO2014059202A1
(en)
|
2012-10-12 |
2014-04-17 |
Bristol-Myers Squibb Company |
Guanidine substituted tetrahydroisoquinoline compounds as factor xia inhibitors
|
CA2863243A1
(en)
*
|
2012-11-30 |
2014-06-05 |
Hangzhou Zylox Pharma Co., Ltd. |
Rafamycin analogs and methods for making same
|
AU2014205366B2
(en)
|
2013-01-09 |
2018-12-20 |
Eckhard R. Podack |
Compositions and methods for the regulation of T regulatory cells using Tl1a-Ig fusion protein
|
KR20150143476A
(ko)
|
2013-03-12 |
2015-12-23 |
미셀 테크놀로지즈, 인코포레이티드 |
생흡수성 생체의학적 임플란트
|
US9738655B2
(en)
|
2013-03-25 |
2017-08-22 |
Bristol-Myers Squibb Company |
Tetrahydroisoquinolines containing substituted azoles as factor XIa inhibitors
|
KR20180059584A
(ko)
|
2013-05-15 |
2018-06-04 |
미셀 테크놀로지즈, 인코포레이티드 |
생흡수성 생체의학적 임플란트
|
CN105899232A
(zh)
|
2013-11-13 |
2016-08-24 |
诺华股份有限公司 |
用于增强免疫应答的mTOR抑制剂
|
ES2918501T3
(es)
|
2013-12-19 |
2022-07-18 |
Novartis Ag |
Receptores de antígenos quiméricos de mesotelina humana y usos de los mismos
|
WO2015090229A1
(en)
|
2013-12-20 |
2015-06-25 |
Novartis Ag |
Regulatable chimeric antigen receptor
|
CN103739616B
(zh)
*
|
2013-12-27 |
2015-12-30 |
福建省微生物研究所 |
含噻唑基雷帕霉素类衍生物及其应用
|
CA2935167C
(en)
|
2014-01-16 |
2022-02-22 |
Musc Foundation For Research Development |
Targeted nanocarriers for the administration of immunosuppressive agents
|
SG11201606209PA
(en)
|
2014-01-31 |
2016-08-30 |
Bristol Myers Squibb Co |
Macrocycles with hetrocyclic p2' groups as factor xia inhibitors
|
NO2760821T3
(de)
|
2014-01-31 |
2018-03-10 |
|
|
EP3119425B1
(de)
|
2014-03-15 |
2020-09-23 |
Novartis AG |
Regulierbarer chimärer antigenrezeptor
|
CN106163547A
(zh)
|
2014-03-15 |
2016-11-23 |
诺华股份有限公司 |
使用嵌合抗原受体治疗癌症
|
EP3122376A4
(de)
|
2014-03-27 |
2017-12-20 |
The Brigham and Women's Hospital, Inc. |
Metabolisch aktivierte wirkstoffkonjugate zur überwindung der resistenz in der krebstherapie
|
JP6765966B2
(ja)
|
2014-04-07 |
2020-10-07 |
ノバルティス アーゲー |
抗cd19キメラ抗原受容体を使用する癌の処置
|
JP2017518307A
(ja)
|
2014-06-02 |
2017-07-06 |
チルドレンズ メディカル センター コーポレーション |
免疫調節のための方法および組成物
|
WO2016014553A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
SG10201913765YA
(en)
|
2014-07-21 |
2020-03-30 |
Novartis Ag |
Treatment of cancer using a cd33 chimeric antigen receptor
|
WO2016014530A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
EP3660042B1
(de)
|
2014-07-31 |
2023-01-11 |
Novartis AG |
T-zellen mit teilmengenoptimierten chimären antigenrezeptoren
|
AU2015301460B2
(en)
|
2014-08-14 |
2021-04-08 |
Novartis Ag |
Treatment of cancer using GFR alpha-4 chimeric antigen receptor
|
LT3183268T
(lt)
|
2014-08-19 |
2020-06-10 |
Novartis Ag |
Anti-cd123 chimerinis antigeno receptorius (car), skirtas naudoti vėžio gydymui
|
WO2016036893A1
(en)
|
2014-09-04 |
2016-03-10 |
Bristol-Myers Squibb Company |
Diamide macrocycles that are fxia inhibitors
|
JP6839074B2
(ja)
|
2014-09-17 |
2021-03-03 |
ノバルティス アーゲー |
養子免疫療法のためのキメラ受容体での細胞毒性細胞のターゲティング
|
US9453018B2
(en)
|
2014-10-01 |
2016-09-27 |
Bristol-Myers Squibb Company |
Pyrimidinones as factor XIa inhibitors
|
JP6815992B2
(ja)
|
2014-10-08 |
2021-01-20 |
ノバルティス アーゲー |
キメラ抗原受容体療法に対する治療応答性を予測するバイオマーカーおよびその使用
|
CA2982996A1
(en)
|
2015-04-17 |
2016-10-20 |
David Maxwell Barrett |
Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
|
EP3286211A1
(de)
|
2015-04-23 |
2018-02-28 |
Novartis AG |
Behandlung von krebs mit chimärem antigenrezeptor- und proteinkinase-a-blocker
|
AU2016263176A1
(en)
|
2015-05-20 |
2017-12-07 |
Novartis Ag |
Pharmaceutical combination of everolimus with dactolisib
|
KR20180080230A
(ko)
|
2015-11-11 |
2018-07-11 |
노파르티스 아게 |
미오스타틴 길항제의 용도, 이들을 함유하는 조합물 및 그의 용도
|
KR102565885B1
(ko)
|
2016-07-20 |
2023-08-09 |
유니버시티 오브 유타 리서치 파운데이션 |
Cd229 car t 세포 및 이의 사용 방법
|
US10525083B2
(en)
|
2016-10-07 |
2020-01-07 |
Novartis Ag |
Nucleic acid molecules encoding chimeric antigen receptors comprising a CD20 binding domain
|
BR112019010470A2
(pt)
|
2016-11-23 |
2019-09-10 |
Novartis Ag |
métodos de realce de resposta imune com everolimo, dactolisib ou ambos
|
EP3615055A1
(de)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Zellen, die einen auf bcma abzielenden chimären antigenrezeptor exprimieren, und kombinationsbehandlung mit einem gamma-sekretase-inhibitor
|
US10596165B2
(en)
|
2018-02-12 |
2020-03-24 |
resTORbio, Inc. |
Combination therapies
|
US20210047405A1
(en)
|
2018-04-27 |
2021-02-18 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
WO2019213282A1
(en)
|
2018-05-01 |
2019-11-07 |
Novartis Ag |
Biomarkers for evaluating car-t cells to predict clinical outcome
|
JP2022510573A
(ja)
|
2018-07-23 |
2022-01-27 |
エンクリアー セラピーズ, インク. |
神経障害の治療方法
|
CN113164557A
(zh)
|
2018-07-23 |
2021-07-23 |
因柯利尔疗法公司 |
治疗神经性病症的方法
|
CN114007665A
(zh)
|
2019-04-11 |
2022-02-01 |
因柯利尔疗法公司 |
改善脑脊液的方法及其装置和系统
|
JP2023550544A
(ja)
|
2020-11-03 |
2023-12-01 |
アールディスカバリー エルエルシー |
がんおよびファゴサイトーシス不全に関連する疾患の処置のための療法
|
WO2023288046A1
(en)
|
2021-07-15 |
2023-01-19 |
President And Fellows Of Harvard College |
Compositions and methods relating to cells with adhered particles
|