SI1003903T1 - Process for preparing enantiomerically enriched n-derivatised lactams - Google Patents

Process for preparing enantiomerically enriched n-derivatised lactams

Info

Publication number
SI1003903T1
SI1003903T1 SI9830407T SI9830407T SI1003903T1 SI 1003903 T1 SI1003903 T1 SI 1003903T1 SI 9830407 T SI9830407 T SI 9830407T SI 9830407 T SI9830407 T SI 9830407T SI 1003903 T1 SI1003903 T1 SI 1003903T1
Authority
SI
Slovenia
Prior art keywords
derivatised
lactams
enantiomerically enriched
preparing enantiomerically
preparing
Prior art date
Application number
SI9830407T
Other languages
English (en)
Slovenian (sl)
Inventor
Michael John-Glaxo Wellcome plc DAWSON
Mahmound Glaxo Wellcome plc MAHMOUDIAN
Christopher John-Glaxo Wellcome plc WALLIS
Original Assignee
Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited
Publication of SI1003903T1 publication Critical patent/SI1003903T1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/02Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
SI9830407T 1997-08-22 1998-08-20 Process for preparing enantiomerically enriched n-derivatised lactams SI1003903T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9717928.7A GB9717928D0 (en) 1997-08-22 1997-08-22 Process for the enatioselective hydrolysis of n-derivatised lactams
EP98951307A EP1003903B1 (en) 1997-08-22 1998-08-20 Process for preparing enantiomerically enriched n-derivatised lactams
PCT/EP1998/005291 WO1999010519A1 (en) 1997-08-22 1998-08-20 Process for preparing enantiomerically enriched n-derivatised lactams

Publications (1)

Publication Number Publication Date
SI1003903T1 true SI1003903T1 (en) 2003-08-31

Family

ID=10817952

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9830407T SI1003903T1 (en) 1997-08-22 1998-08-20 Process for preparing enantiomerically enriched n-derivatised lactams

Country Status (35)

Country Link
US (1) US6340587B1 (da)
EP (1) EP1003903B1 (da)
JP (1) JP3565868B2 (da)
KR (1) KR100479894B1 (da)
CN (1) CN1133749C (da)
AP (1) AP1104A (da)
AR (1) AR016395A1 (da)
AT (1) ATE233323T1 (da)
AU (1) AU738897B2 (da)
BR (1) BR9810472B1 (da)
CA (1) CA2295017A1 (da)
CZ (1) CZ294302B6 (da)
DE (1) DE69811677T2 (da)
DK (1) DK1003903T3 (da)
EA (1) EA001964B1 (da)
EE (1) EE03934B1 (da)
ES (1) ES2193568T3 (da)
GB (1) GB9717928D0 (da)
HK (1) HK1025796A1 (da)
HR (1) HRP990408B1 (da)
HU (1) HU222657B1 (da)
ID (1) ID25830A (da)
IL (1) IL133541A (da)
IN (1) IN183908B (da)
IS (1) IS2201B (da)
NO (1) NO320081B1 (da)
NZ (1) NZ501880A (da)
PL (1) PL191108B1 (da)
PT (1) PT1003903E (da)
RS (1) RS49542B (da)
SI (1) SI1003903T1 (da)
SK (1) SK282782B6 (da)
TR (1) TR199903210T2 (da)
TW (1) TW589301B (da)
WO (1) WO1999010519A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2214876T3 (es) 1998-07-09 2004-09-16 Lonza Ag Procedimiento de preparacion de derivaods de (1r,4s)-2-azabiciclo 2.2.1 hept-5-en-3-ona.
DE19962543A1 (de) 1999-12-23 2001-07-05 Degussa Chromatographische Enantiomerentrennung von bicyclischen Lactamen
US6780635B2 (en) 2001-12-27 2004-08-24 Council Of Scientific And Industrial Research Process for the preparation of optically active azabicyclo heptanone derivatives
DE60211646T2 (de) * 2002-03-28 2007-05-24 Council Of Scientific And Industrial Research Verfahren zur Herstellung von optisch aktiven Azabicycloheptanone-Derivaten
HU227663B1 (en) * 2007-07-09 2011-10-28 Univ Szegedi Resolution process
KR20170078868A (ko) 2010-01-27 2017-07-07 비이브 헬쓰케어 컴퍼니 항바이러스 치료
CN103695495B (zh) * 2014-01-14 2014-08-27 营口三征新科技化工有限公司 一种制备(1R,4s)-(-)-2-氮杂双环[2,2,1]庚-5-烯-3-酮的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69016739T2 (de) * 1989-10-16 1995-06-14 Chiroscience Ltd Chirale Azabicycloheptanone und Verfahren zu ihrer Herstellung.
GB9108384D0 (en) * 1991-04-19 1991-06-05 Enzymatix Ltd Bicycloheptanes
SK284810B6 (sk) * 1997-05-13 2005-12-01 Lonza Ag Spôsob výroby (1S,4R)- alebo (1R,4S)-4-(2-amino-6-chlór-9-H- purín-9-yl)-2-cyklopentén-1-metanolu

Also Published As

Publication number Publication date
GB9717928D0 (en) 1997-10-29
CN1133749C (zh) 2004-01-07
BR9810472B1 (pt) 2011-01-11
CA2295017A1 (en) 1999-03-04
IS2201B (is) 2007-02-15
AP9901721A0 (en) 1999-12-31
HK1025796A1 (en) 2000-11-24
HUP0002661A2 (hu) 2000-12-28
NO996368L (no) 2000-02-21
IL133541A0 (en) 2001-04-30
IS5297A (is) 1999-12-14
RS49542B (sr) 2007-02-05
PL191108B1 (pl) 2006-03-31
ID25830A (id) 2000-11-09
EP1003903A1 (en) 2000-05-31
EA001964B1 (ru) 2001-10-22
JP3565868B2 (ja) 2004-09-15
BR9810472A (pt) 2000-09-19
AR016395A1 (es) 2001-07-04
AU738897B2 (en) 2001-09-27
SK184499A3 (en) 2000-09-12
AU9738698A (en) 1999-03-16
TR199903210T2 (xx) 2000-07-21
EA199901059A1 (ru) 2000-08-28
EE200000075A (et) 2000-10-16
US6340587B1 (en) 2002-01-22
KR20010014078A (ko) 2001-02-26
CN1261405A (zh) 2000-07-26
CZ294302B6 (cs) 2004-11-10
EP1003903B1 (en) 2003-02-26
DE69811677D1 (de) 2003-04-03
CZ471699A3 (cs) 2000-06-14
DK1003903T3 (da) 2003-06-10
NO320081B1 (no) 2005-10-17
HU222657B1 (hu) 2003-09-29
HRP990408B1 (en) 2006-05-31
IL133541A (en) 2003-10-31
SK282782B6 (sk) 2002-12-03
YU69399A (sh) 2002-06-19
ES2193568T3 (es) 2003-11-01
NZ501880A (en) 2001-08-31
PL337647A1 (en) 2000-08-28
DE69811677T2 (de) 2003-10-16
TW589301B (en) 2004-06-01
HRP990408A2 (en) 2000-04-30
AP1104A (en) 2002-09-04
PT1003903E (pt) 2003-06-30
HUP0002661A3 (en) 2001-12-28
JP2001504354A (ja) 2001-04-03
WO1999010519A1 (en) 1999-03-04
ATE233323T1 (de) 2003-03-15
KR100479894B1 (ko) 2005-03-30
IN183908B (da) 2000-05-13
EE03934B1 (et) 2002-12-16
NO996368D0 (no) 1999-12-21

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