HRP990408B1 - Process for preparing enantiomerically enriched n-derivatised lactams - Google Patents

Process for preparing enantiomerically enriched n-derivatised lactams

Info

Publication number
HRP990408B1
HRP990408B1 HR990408A HRP990408A HRP990408B1 HR P990408 B1 HRP990408 B1 HR P990408B1 HR 990408 A HR990408 A HR 990408A HR P990408 A HRP990408 A HR P990408A HR P990408 B1 HRP990408 B1 HR P990408B1
Authority
HR
Croatia
Prior art keywords
derivatised
lactams
enantiomerically enriched
preparing enantiomerically
azabicyclo
Prior art date
Application number
HR990408A
Other languages
English (en)
Croatian (hr)
Inventor
John Dawson Michael
Mahmoudian Mahmoud
John Wallis Christopher
Original Assignee
Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited
Publication of HRP990408A2 publication Critical patent/HRP990408A2/hr
Publication of HRP990408B1 publication Critical patent/HRP990408B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HR990408A 1997-08-22 1999-12-23 Process for preparing enantiomerically enriched n-derivatised lactams HRP990408B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9717928.7A GB9717928D0 (en) 1997-08-22 1997-08-22 Process for the enatioselective hydrolysis of n-derivatised lactams

Publications (2)

Publication Number Publication Date
HRP990408A2 HRP990408A2 (en) 2000-04-30
HRP990408B1 true HRP990408B1 (en) 2006-05-31

Family

ID=10817952

Family Applications (1)

Application Number Title Priority Date Filing Date
HR990408A HRP990408B1 (en) 1997-08-22 1999-12-23 Process for preparing enantiomerically enriched n-derivatised lactams

Country Status (35)

Country Link
US (1) US6340587B1 (xx)
EP (1) EP1003903B1 (xx)
JP (1) JP3565868B2 (xx)
KR (1) KR100479894B1 (xx)
CN (1) CN1133749C (xx)
AP (1) AP1104A (xx)
AR (1) AR016395A1 (xx)
AT (1) ATE233323T1 (xx)
AU (1) AU738897B2 (xx)
BR (1) BR9810472B1 (xx)
CA (1) CA2295017A1 (xx)
CZ (1) CZ294302B6 (xx)
DE (1) DE69811677T2 (xx)
DK (1) DK1003903T3 (xx)
EA (1) EA001964B1 (xx)
EE (1) EE03934B1 (xx)
ES (1) ES2193568T3 (xx)
GB (1) GB9717928D0 (xx)
HK (1) HK1025796A1 (xx)
HR (1) HRP990408B1 (xx)
HU (1) HU222657B1 (xx)
ID (1) ID25830A (xx)
IL (1) IL133541A (xx)
IN (1) IN183908B (xx)
IS (1) IS2201B (xx)
NO (1) NO320081B1 (xx)
NZ (1) NZ501880A (xx)
PL (1) PL191108B1 (xx)
PT (1) PT1003903E (xx)
RS (1) RS49542B (xx)
SI (1) SI1003903T1 (xx)
SK (1) SK282782B6 (xx)
TR (1) TR199903210T2 (xx)
TW (1) TW589301B (xx)
WO (1) WO1999010519A1 (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1095160B1 (de) * 1998-07-09 2004-01-28 Lonza AG Verfahren zur herstellung von (1r,4s)-2-azabicyclo 2.2.1 hept-5-en-3-on-derivaten
DE19962543A1 (de) * 1999-12-23 2001-07-05 Degussa Chromatographische Enantiomerentrennung von bicyclischen Lactamen
US6780635B2 (en) * 2001-12-27 2004-08-24 Council Of Scientific And Industrial Research Process for the preparation of optically active azabicyclo heptanone derivatives
EP1348765B1 (en) * 2002-03-28 2006-05-24 Council of Scientific and Industrial Research Process for the preparation of optically active azabicyclo heptanone derivatives
HU227663B1 (en) * 2007-07-09 2011-10-28 Univ Szegedi Resolution process
TR201807704T4 (tr) 2010-01-27 2018-06-21 Viiv Healthcare Co Anti-viral tedavi.
CN103695495B (zh) * 2014-01-14 2014-08-27 营口三征新科技化工有限公司 一种制备(1R,4s)-(-)-2-氮杂双环[2,2,1]庚-5-烯-3-酮的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0424064T3 (da) * 1989-10-16 1995-06-26 Chiroscience Ltd Chirale azabicycloheptanoner og fremgangsmåde til fremstilling deraf
GB9108384D0 (en) 1991-04-19 1991-06-05 Enzymatix Ltd Bicycloheptanes
SK284810B6 (sk) * 1997-05-13 2005-12-01 Lonza Ag Spôsob výroby (1S,4R)- alebo (1R,4S)-4-(2-amino-6-chlór-9-H- purín-9-yl)-2-cyklopentén-1-metanolu

Also Published As

Publication number Publication date
CN1133749C (zh) 2004-01-07
HRP990408A2 (en) 2000-04-30
CA2295017A1 (en) 1999-03-04
NO996368L (no) 2000-02-21
BR9810472B1 (pt) 2011-01-11
JP3565868B2 (ja) 2004-09-15
DE69811677T2 (de) 2003-10-16
IN183908B (xx) 2000-05-13
JP2001504354A (ja) 2001-04-03
DE69811677D1 (de) 2003-04-03
PL191108B1 (pl) 2006-03-31
GB9717928D0 (en) 1997-10-29
HUP0002661A3 (en) 2001-12-28
EA199901059A1 (ru) 2000-08-28
AU9738698A (en) 1999-03-16
HUP0002661A2 (hu) 2000-12-28
CN1261405A (zh) 2000-07-26
IL133541A (en) 2003-10-31
NZ501880A (en) 2001-08-31
EP1003903A1 (en) 2000-05-31
AP1104A (en) 2002-09-04
PT1003903E (pt) 2003-06-30
EE200000075A (et) 2000-10-16
EE03934B1 (et) 2002-12-16
TW589301B (en) 2004-06-01
AU738897B2 (en) 2001-09-27
KR100479894B1 (ko) 2005-03-30
HU222657B1 (hu) 2003-09-29
EP1003903B1 (en) 2003-02-26
BR9810472A (pt) 2000-09-19
AR016395A1 (es) 2001-07-04
HK1025796A1 (en) 2000-11-24
KR20010014078A (ko) 2001-02-26
SI1003903T1 (en) 2003-08-31
EA001964B1 (ru) 2001-10-22
ES2193568T3 (es) 2003-11-01
YU69399A (sh) 2002-06-19
PL337647A1 (en) 2000-08-28
IS2201B (is) 2007-02-15
WO1999010519A1 (en) 1999-03-04
IS5297A (is) 1999-12-14
RS49542B (sr) 2007-02-05
ATE233323T1 (de) 2003-03-15
US6340587B1 (en) 2002-01-22
CZ471699A3 (cs) 2000-06-14
IL133541A0 (en) 2001-04-30
NO996368D0 (no) 1999-12-21
NO320081B1 (no) 2005-10-17
SK184499A3 (en) 2000-09-12
TR199903210T2 (xx) 2000-07-21
DK1003903T3 (da) 2003-06-10
AP9901721A0 (en) 1999-12-31
CZ294302B6 (cs) 2004-11-10
ID25830A (id) 2000-11-09
SK282782B6 (sk) 2002-12-03

Similar Documents

Publication Publication Date Title
HU9501329D0 (en) Novel 3,3-diphenylpropylamines, their use and preparation
TW341565B (en) Indole derivatives processes and intermediates for their preparation and pharmaceutical compositions containing them
CA2174000A1 (en) Process for the preparation of a substituted 2,5-diamino-3-hydroxyhexane
ES8202810A1 (es) Un procedimiento para la preparacion de espiro(ciclohexano- 1,1'(3'h)-isobenzofuranos)
HRP990408B1 (en) Process for preparing enantiomerically enriched n-derivatised lactams
AU3170597A (en) Process for the preparation of amino alcohols and derivatives thereof
CA2031756A1 (en) Isatine derivatives, their preparation and use
AU6851396A (en) Novel fused isoquinolines as dopamine receptor ligands
PT85869A (en) Process for preparing amino acid derivative anti-convulsant
ES8705464A1 (es) Un procedimiento para la preparacion de nuevos peptidos.
GB9707413D0 (en) Process
NZ217813A (en) Dipeptides and process for their preparation using an enzyme coupling agent
WO2000048549A3 (en) Anticonvulsant derivatives useful in treating essential tremor
HU913759D0 (en) Process for the production of indole compounds
SG47459A1 (en) Process for preparing enantiomerically pure imidazo(4,5,1)(1,4)benzodiazepin-2(1H)-thiones
EP0167922A3 (en) Pyrrolo û1,2-b¨ û1,2,5¨ triazepines, a process and intermediates for their preparation and their use as medicaments
ES2145295T3 (es) Procedimiento de amidacion con apertura de anillo.
JPS5750958A (en) Preparation of tryptophan derivative
TH57841A (th) กรรมวิธีไฮโดรไลซิสที่เลือกจำเพาะต่ออีแนนทิโอเมอร์ของ n-เดริเวไทซ์แลกแทม
DE50009160D1 (de) Verfahren zur herstellung von optisch aktiven 3,3,3- trifluormethyl- 2- alkylpropionsäurederivaten

Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
B1PR Patent granted
ODRP Renewal fee for the maintenance of a patent

Payment date: 20170803

Year of fee payment: 20

PB20 Patent expired after termination of 20 years

Effective date: 20180820