DK0424064T3 - Chirale azabicycloheptanoner og fremgangsmåde til fremstilling deraf - Google Patents

Chirale azabicycloheptanoner og fremgangsmåde til fremstilling deraf

Info

Publication number
DK0424064T3
DK0424064T3 DK90311253.0T DK90311253T DK0424064T3 DK 0424064 T3 DK0424064 T3 DK 0424064T3 DK 90311253 T DK90311253 T DK 90311253T DK 0424064 T3 DK0424064 T3 DK 0424064T3
Authority
DK
Denmark
Prior art keywords
chiral
azabicycloheptanones
preparation
lactamase
amino
Prior art date
Application number
DK90311253.0T
Other languages
English (en)
Inventor
Christopher Thomas Evans
Stanley Michael Roberts
Original Assignee
Chiroscience Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898923278A external-priority patent/GB8923278D0/en
Priority claimed from GB898924209A external-priority patent/GB8924209D0/en
Priority claimed from GB909000995A external-priority patent/GB9000995D0/en
Application filed by Chiroscience Ltd filed Critical Chiroscience Ltd
Application granted granted Critical
Publication of DK0424064T3 publication Critical patent/DK0424064T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/005—Amino acids other than alpha- or beta amino acids, e.g. gamma amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK90311253.0T 1989-10-16 1990-10-15 Chirale azabicycloheptanoner og fremgangsmåde til fremstilling deraf DK0424064T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB898923278A GB8923278D0 (en) 1989-10-16 1989-10-16 Chiral compounds
GB898924209A GB8924209D0 (en) 1989-10-27 1989-10-27 Chiral compounds
GB909000995A GB9000995D0 (en) 1990-01-17 1990-01-17 Chiral compounds

Publications (1)

Publication Number Publication Date
DK0424064T3 true DK0424064T3 (da) 1995-06-26

Family

ID=27264742

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90311253.0T DK0424064T3 (da) 1989-10-16 1990-10-15 Chirale azabicycloheptanoner og fremgangsmåde til fremstilling deraf

Country Status (8)

Country Link
US (2) US5498625A (da)
EP (1) EP0424064B1 (da)
JP (1) JP2648013B2 (da)
AT (1) ATE118208T1 (da)
DE (1) DE69016739T2 (da)
DK (1) DK0424064T3 (da)
ES (1) ES2067693T3 (da)
GR (1) GR3015887T3 (da)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
GB9108384D0 (en) * 1991-04-19 1991-06-05 Enzymatix Ltd Bicycloheptanes
GB9204015D0 (en) 1992-02-25 1992-04-08 Wellcome Found Therapeutic nucleosides
DE4420751A1 (de) * 1994-06-15 1995-12-21 Basf Ag Verfahren zur Herstellung von enantiomerenreinen Lactamen
US5898075A (en) * 1994-08-19 1999-04-27 Chirotech Technology Limited Process for the separation of the enantiomers of a bicyclic lactam
GB9618340D0 (en) 1996-09-03 1996-10-16 Chiroscience Ltd Microorganism and its use
GB9625455D0 (en) * 1996-12-07 1997-01-22 Glaxo Group Ltd Process for resolving mixtures of carbocyclic steroisomers
GB9717928D0 (en) 1997-08-22 1997-10-29 Glaxo Group Ltd Process for the enatioselective hydrolysis of n-derivatised lactams
US6136327A (en) 1997-12-01 2000-10-24 Alza Corporation Stereospecific delivery of a drug using electrotransport
US6529730B1 (en) * 1998-05-15 2003-03-04 Conexant Systems, Inc System and method for adaptive multi-rate (AMR) vocoder rate adaption
EP1095160B1 (de) * 1998-07-09 2004-01-28 Lonza AG Verfahren zur herstellung von (1r,4s)-2-azabicyclo 2.2.1 hept-5-en-3-on-derivaten
GB9907415D0 (en) * 1999-03-31 1999-05-26 Chirotech Technology Ltd Biocatalyst and its use
CZ20014656A3 (cs) 1999-06-28 2002-11-13 Biocryst Pharmaceuticals, Inc. Způsob přípravy (-)-(1S,4R) N-chráněných 4-amino-2-cyklopenten-1-karboxylát esterů
DE19962543A1 (de) 1999-12-23 2001-07-05 Degussa Chromatographische Enantiomerentrennung von bicyclischen Lactamen
WO2002032885A1 (fr) * 2000-10-18 2002-04-25 Kuraray Co., Ltd. Preparation d'esters d'acide amino-2-aza-1-oxybicyclo[3.3.0]oct-2-ene-6-carboxylique 4-n substitues et preparation de leurs produits intermediaires
US6780635B2 (en) 2001-12-27 2004-08-24 Council Of Scientific And Industrial Research Process for the preparation of optically active azabicyclo heptanone derivatives
EP1493124B1 (en) * 2002-03-13 2006-07-26 O-Pen ApS A touch pad and a method of operating the touch pad
EP1348765B1 (en) * 2002-03-28 2006-05-24 Council of Scientific and Industrial Research Process for the preparation of optically active azabicyclo heptanone derivatives
JP2006523869A (ja) * 2003-03-12 2006-10-19 オー−プン・アンパルトセルスカブ 放射線を放射する要素の位置を測定するシステム及び方法
ATE514991T1 (de) 2003-09-12 2011-07-15 Flatfrog Lab Ab System und verfahren zur bestimmung einer position eines strahlungsstreu-/- reflexionselements
US7442914B2 (en) * 2003-09-12 2008-10-28 Flatfrog Laboratories Ab System and method of determining a position of a radiation emitting element
PE20080209A1 (es) 2006-06-23 2008-05-15 Smithkline Beecham Corp Derivados de glicina como inhibidores de prolil hidroxilasa
HU227663B1 (en) * 2007-07-09 2011-10-28 Univ Szegedi Resolution process
SE533704C2 (sv) 2008-12-05 2010-12-07 Flatfrog Lab Ab Pekkänslig apparat och förfarande för drivning av densamma
US10168835B2 (en) 2012-05-23 2019-01-01 Flatfrog Laboratories Ab Spatial resolution in touch displays
WO2014168567A1 (en) 2013-04-11 2014-10-16 Flatfrog Laboratories Ab Tomographic processing for touch detection
US9874978B2 (en) 2013-07-12 2018-01-23 Flatfrog Laboratories Ab Partial detect mode
US10146376B2 (en) 2014-01-16 2018-12-04 Flatfrog Laboratories Ab Light coupling in TIR-based optical touch systems
US10126882B2 (en) 2014-01-16 2018-11-13 Flatfrog Laboratories Ab TIR-based optical touch systems of projection-type
WO2015199602A1 (en) 2014-06-27 2015-12-30 Flatfrog Laboratories Ab Detection of surface contamination
CN107209608A (zh) 2015-01-28 2017-09-26 平蛙实验室股份公司 动态触摸隔离帧
US10318074B2 (en) 2015-01-30 2019-06-11 Flatfrog Laboratories Ab Touch-sensing OLED display with tilted emitters
EP3256936A4 (en) 2015-02-09 2018-10-17 FlatFrog Laboratories AB Optical touch system comprising means for projecting and detecting light beams above and inside a transmissive panel
CN107250855A (zh) 2015-03-02 2017-10-13 平蛙实验室股份公司 用于光耦合的光学部件
CN108369470B (zh) 2015-12-09 2022-02-08 平蛙实验室股份公司 改进的触控笔识别
EP3545392A4 (en) 2016-11-24 2020-07-29 FlatFrog Laboratories AB AUTOMATIC TACTILE SIGNAL OPTIMIZATION
KR102495467B1 (ko) 2016-12-07 2023-02-06 플라트프로그 라보라토리즈 에이비 개선된 터치 장치
US10963104B2 (en) 2017-02-06 2021-03-30 Flatfrog Laboratories Ab Optical coupling in touch-sensing systems
WO2018174786A1 (en) 2017-03-22 2018-09-27 Flatfrog Laboratories Pen differentiation for touch displays
EP4036697A1 (en) 2017-03-28 2022-08-03 FlatFrog Laboratories AB Optical touch sensing apparatus
CN117311543A (zh) 2017-09-01 2023-12-29 平蛙实验室股份公司 触摸感测设备
US11567610B2 (en) 2018-03-05 2023-01-31 Flatfrog Laboratories Ab Detection line broadening
US11943563B2 (en) 2019-01-25 2024-03-26 FlatFrog Laboratories, AB Videoconferencing terminal and method of operating the same
JP2023512682A (ja) 2020-02-10 2023-03-28 フラットフロッグ ラボラトリーズ アーベー 改良型タッチ検知装置

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3069830D1 (en) * 1979-09-13 1985-01-31 Wellcome Found Benzopyran compounds, useful as chemotherapeutic agents
US4421767A (en) * 1981-06-01 1983-12-20 Merrell Toraude Et Compagnie Compounds and methods for treating depression

Also Published As

Publication number Publication date
US5688933A (en) 1997-11-18
GR3015887T3 (en) 1995-07-31
JPH03218380A (ja) 1991-09-25
DE69016739D1 (de) 1995-03-23
ES2067693T3 (es) 1995-04-01
JP2648013B2 (ja) 1997-08-27
EP0424064A1 (en) 1991-04-24
US5498625A (en) 1996-03-12
EP0424064B1 (en) 1995-02-08
DE69016739T2 (de) 1995-06-14
ATE118208T1 (de) 1995-02-15

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