SG176443A1 - Compounds for inhibiting mitotic progression - Google Patents

Compounds for inhibiting mitotic progression Download PDF

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Publication number
SG176443A1
SG176443A1 SG2011080652A SG2011080652A SG176443A1 SG 176443 A1 SG176443 A1 SG 176443A1 SG 2011080652 A SG2011080652 A SG 2011080652A SG 2011080652 A SG2011080652 A SG 2011080652A SG 176443 A1 SG176443 A1 SG 176443A1
Authority
SG
Singapore
Prior art keywords
cancer
group
compound
aliphatic
optionally substituted
Prior art date
Application number
SG2011080652A
Other languages
English (en)
Inventor
Christopher F Claiborne
Todd B Sells
Stephen G Stroud
Original Assignee
Millennium Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39315133&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG176443(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Millennium Pharm Inc filed Critical Millennium Pharm Inc
Publication of SG176443A1 publication Critical patent/SG176443A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SG2011080652A 2006-11-16 2007-11-14 Compounds for inhibiting mitotic progression SG176443A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85934006P 2006-11-16 2006-11-16

Publications (1)

Publication Number Publication Date
SG176443A1 true SG176443A1 (en) 2011-12-29

Family

ID=39315133

Family Applications (2)

Application Number Title Priority Date Filing Date
SG2011080652A SG176443A1 (en) 2006-11-16 2007-11-14 Compounds for inhibiting mitotic progression
SG10201503350TA SG10201503350TA (en) 2006-11-16 2007-11-14 Compounds for inhibiting mitotic progression

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201503350TA SG10201503350TA (en) 2006-11-16 2007-11-14 Compounds for inhibiting mitotic progression

Country Status (34)

Country Link
US (7) US8026246B2 (enExample)
EP (4) EP2944639B1 (enExample)
JP (3) JP5102839B2 (enExample)
KR (2) KR101342014B1 (enExample)
CN (2) CN103483343B (enExample)
AR (1) AR064246A1 (enExample)
AT (1) ATE556076T1 (enExample)
AU (1) AU2007322046B2 (enExample)
BR (1) BRPI0718803B8 (enExample)
CA (1) CA2669680C (enExample)
CL (1) CL2007003244A1 (enExample)
CR (3) CR10782A (enExample)
CY (1) CY1112828T1 (enExample)
DK (2) DK2086981T3 (enExample)
EA (1) EA015779B1 (enExample)
ES (3) ES2537451T3 (enExample)
GE (1) GEP20125459B (enExample)
HR (2) HRP20120490T1 (enExample)
IL (1) IL198690A0 (enExample)
MA (1) MA30988B1 (enExample)
MX (3) MX348568B (enExample)
MY (1) MY153243A (enExample)
NO (1) NO343338B1 (enExample)
NZ (3) NZ611898A (enExample)
PH (1) PH12012502057B1 (enExample)
PL (2) PL2086981T3 (enExample)
PT (2) PT2086981E (enExample)
RS (2) RS52313B (enExample)
SG (2) SG176443A1 (enExample)
SI (2) SI2086981T1 (enExample)
TW (1) TWI401255B (enExample)
UA (1) UA94129C2 (enExample)
WO (1) WO2008063525A1 (enExample)
ZA (1) ZA200903279B (enExample)

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WO2010074724A1 (en) * 2008-12-22 2010-07-01 Millennium Pharmaceuticals, Inc. Combination of aurora kinase inhibitors and anti-cd20 antibodies
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RU2012140021A (ru) * 2010-02-19 2014-03-27 Миллениум Фармасьютикалз, Инк. КРИСТАЛЛИЧЕСКИЕ ФОРМЫ 4-{[9-ХЛОР-7-(2-ФТОР-6-МЕТОКСИФЕНИЛ)-5Н-ПИРИМИДО[5,4-d][2]БЕНЗАЗЕПИН-2-ИЛ]АМИНО}-2-МЕТОКСИБЕНЗОАТА НАТРИЯ
US20120107304A1 (en) 2010-04-27 2012-05-03 Boehringer Ingelheim International Gmbh Combination therapy in treatment of oncological and fibrotic diseases
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WO2017044567A1 (en) 2015-09-09 2017-03-16 Icahn School Of Medicine At Mount Sinai Heterocyclic constrained tricyclic sulfonamides as anti-cancer agents
CA2997784A1 (en) 2015-09-09 2017-03-16 Icahn School Of Medicine At Mount Sinai Heterocyclic constrained tricyclic sulfonamides as anti-cancer agents
WO2017146253A1 (ja) 2016-02-26 2017-08-31 公益財団法人がん研究会 Ｈｐ１の機能に着目した抗癌剤のスクリーニング方法及び評価系
AU2017233898B2 (en) 2016-03-15 2022-12-15 Oryzon Genomics, S.A. Combinations of LSD1 inhibitors for use in the treatment of solid tumors
JP6188986B1 (ja) * 2017-03-23 2017-08-30 株式会社ノエビア 時計遺伝子発現量調整剤及びエラスチン産生促進剤
WO2019195658A1 (en) 2018-04-05 2019-10-10 Dana-Farber Cancer Institute, Inc. Sting levels as a biomarker for cancer immunotherapy
WO2020049208A1 (es) 2018-09-09 2020-03-12 Fundacio Privada Institut De Recerca De La Sida - Caixa Aurora cinasa como diana para tratar, prevenir o curar una infección por vih o sida
WO2021041532A1 (en) 2019-08-26 2021-03-04 Dana-Farber Cancer Institute, Inc. Use of heparin to promote type 1 interferon signaling
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Also Published As

Publication number Publication date
ATE556076T1 (de) 2012-05-15
US20110312943A1 (en) 2011-12-22
CA2669680A1 (en) 2008-05-29
PL2086981T3 (pl) 2012-09-28
BRPI0718803A2 (pt) 2013-12-03
MA30988B1 (fr) 2009-12-01
CA2669680C (en) 2012-04-10
US20190031662A1 (en) 2019-01-31
US11958855B2 (en) 2024-04-16
DK2086981T3 (da) 2012-08-06
US8026246B2 (en) 2011-09-27
CN101547924A (zh) 2009-09-30
US20080167292A1 (en) 2008-07-10
AR064246A1 (es) 2009-03-25
NZ611898A (en) 2015-01-30
IL198690A0 (en) 2010-02-17
TWI401255B (zh) 2013-07-11
GEP20125459B (en) 2012-03-26
CY1112828T1 (el) 2016-02-10
CR20140544A (es) 2015-01-12
PH12012502057A1 (en) 2015-09-14
RS52313B (sr) 2012-12-31
SG10201503350TA (en) 2015-06-29
EP2944639B1 (en) 2017-01-04
BRPI0718803B8 (pt) 2021-05-25
EP2497773A1 (en) 2012-09-12
US10836766B2 (en) 2020-11-17
CN103483343B (zh) 2016-06-01
UA94129C2 (ru) 2011-04-11
ES2384123T3 (es) 2012-06-29
AU2007322046B2 (en) 2012-04-05
MX348568B (es) 2017-06-20
HK1134672A1 (en) 2010-05-07
CN101547924B (zh) 2013-09-25
PT2497772E (pt) 2015-02-05
CL2007003244A1 (es) 2008-04-04
EP2086981A1 (en) 2009-08-12
RS53788B1 (sr) 2015-06-30
NO343338B1 (no) 2019-02-04
MY153243A (en) 2015-01-29
BRPI0718803B1 (pt) 2020-11-17
KR101110458B1 (ko) 2012-03-13
EP2497772A1 (en) 2012-09-12
MX343391B (es) 2016-11-04
US20210214361A1 (en) 2021-07-15
KR101342014B1 (ko) 2013-12-19
HK1175778A1 (en) 2013-07-12
EP2497772B1 (en) 2014-10-29
EA200970486A1 (ru) 2009-10-30
KR20090091173A (ko) 2009-08-26
US9765076B2 (en) 2017-09-19
CN103483343A (zh) 2014-01-01
PL2497772T3 (pl) 2015-05-29
US9988384B2 (en) 2018-06-05
CR20140154A (es) 2014-07-23
JP5102839B2 (ja) 2012-12-19
ZA200903279B (en) 2010-07-28
SI2086981T1 (sl) 2012-12-31
JP2010510215A (ja) 2010-04-02
CR10782A (es) 2009-06-24
EA015779B1 (ru) 2011-12-30
HRP20120490T1 (hr) 2012-07-31
ES2537451T3 (es) 2015-06-08
EP2944639A1 (en) 2015-11-18
PH12012502057B1 (en) 2018-10-24
HRP20150047T1 (en) 2015-03-13
US20110312942A1 (en) 2011-12-22
DK2497772T3 (en) 2015-01-19
KR20110113210A (ko) 2011-10-14
JP5452811B2 (ja) 2014-03-26
US20240400567A1 (en) 2024-12-05
NZ577042A (en) 2012-03-30
ES2528793T3 (es) 2015-02-12
EP2086981B1 (en) 2012-05-02
NZ597252A (en) 2013-06-28
AU2007322046A1 (en) 2008-05-29
JP2014055166A (ja) 2014-03-27
HK1175777A1 (en) 2013-07-12
SI2497772T1 (sl) 2015-03-31
EP2497773B1 (en) 2015-02-25
MX2009004670A (es) 2009-05-15
PT2086981E (pt) 2012-06-20
TW200829589A (en) 2008-07-16
JP2012006965A (ja) 2012-01-12
NO20091864L (no) 2009-06-15
HK1217699A1 (en) 2017-01-20
US20150166545A1 (en) 2015-06-18
WO2008063525A1 (en) 2008-05-29

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