SG11201910136RA - Methods for making high intensity sweeteners - Google Patents

Methods for making high intensity sweeteners

Info

Publication number
SG11201910136RA
SG11201910136RA SG11201910136RA SG11201910136RA SG 11201910136R A SG11201910136R A SG 11201910136RA SG 11201910136R A SG11201910136R A SG 11201910136RA SG 11201910136R A SG11201910136R A SG 11201910136RA
Authority
SG
Singapore
Prior art keywords
san diego
international
california
nexus
drive
Prior art date
Application number
Other languages
English (en)
Inventor
Andrew Patron
Chris Noriega
Rama Manam
Justin Colquitt
Nathan Faber
Helge Zieler
Justin Stege
Original Assignee
Firmenich Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Firmenich Incorporated filed Critical Firmenich Incorporated
Publication of SG11201910136RA publication Critical patent/SG11201910136RA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/14Yeasts or derivatives thereof
    • A23L33/145Extracts
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52Adding ingredients
    • A23L2/60Sweeteners
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30Artificial sweetening agents
    • A23L27/33Artificial sweetening agents containing sugars or derivatives
    • A23L27/36Terpene glycosides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J17/005Glycosides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0012Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0036Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
    • C12N9/0038Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
    • C12N9/0042NADPH-cytochrome P450 reductase (1.6.2.4)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2434Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/244Endo-1,3(4)-beta-glucanase (3.2.1.6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90Isomerases (5.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids
    • C12P33/12Acting on D ring
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids
    • C12P33/20Preparation of steroids containing heterocyclic rings
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y106/00Oxidoreductases acting on NADH or NADPH (1.6)
    • C12Y106/02Oxidoreductases acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
    • C12Y106/02004NADPH-hemoprotein reductase (1.6.2.4), i.e. NADP-cytochrome P450-reductase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01006Endo-1,3(4)-beta-glucanase (3.2.1.6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y504/00Intramolecular transferases (5.4)
    • C12Y504/99Intramolecular transferases (5.4) transferring other groups (5.4.99)
    • C12Y504/990032-Acetolactate mutase (5.4.99.3)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/18Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/56Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Seasonings (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)
SG11201910136R 2017-05-03 2018-05-02 Methods for making high intensity sweeteners SG11201910136RA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762501018P 2017-05-03 2017-05-03
US201762551750P 2017-08-29 2017-08-29
PCT/US2018/030627 WO2018204483A2 (fr) 2017-05-03 2018-05-02 Procédés de fabrication d'édulcorants à haute intensité

Publications (1)

Publication Number Publication Date
SG11201910136RA true SG11201910136RA (en) 2019-11-28

Family

ID=64016614

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201910136R SG11201910136RA (en) 2017-05-03 2018-05-02 Methods for making high intensity sweeteners

Country Status (11)

Country Link
US (2) US11060124B2 (fr)
EP (1) EP3615679A4 (fr)
JP (2) JP7285786B2 (fr)
CN (1) CN111108213A (fr)
BR (1) BR112019023104A2 (fr)
MX (2) MX2019012940A (fr)
PH (1) PH12019502456A1 (fr)
RU (1) RU2767792C2 (fr)
SG (1) SG11201910136RA (fr)
TW (1) TW201843304A (fr)
WO (1) WO2018204483A2 (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3368542B1 (fr) 2015-10-29 2022-06-22 Firmenich Incorporated Édulcorants à intensité élevée
GB201805576D0 (en) * 2018-04-04 2018-05-16 Optibiotix Ltd Sweeteners and methods of production thereof
BR112021008929A2 (pt) * 2018-11-07 2021-08-17 Firmenich Incorporated métodos para fazer edulcorantes de alta intensidade
CN113286523A (zh) * 2018-11-07 2021-08-20 弗门尼舍公司 制备高强度甜味剂的方法
CN113302298A (zh) * 2018-11-09 2021-08-24 银杏生物制品公司 罗汉果甙的生物合成
EP3947701A1 (fr) 2019-04-02 2022-02-09 Novozymes A/S Procédé de production d'un produit de fermentation
JP2022525490A (ja) * 2019-04-04 2022-05-17 フイルメニツヒ ソシエテ アノニム モグロシド化合物およびその使用
CN110669094B (zh) * 2019-10-14 2021-12-21 上海交通大学 罗汉果新苷及其制备方法
EP4048782A4 (fr) * 2019-10-25 2023-11-22 Ginkgo Bioworks, Inc. Biosynthèse de mogrosides
CN110726787B (zh) * 2019-11-11 2022-10-11 广西中烟工业有限责任公司 一种分析七种罗汉果皂苷的lc-ms/ms负离子模式检测方法
CN110669809B (zh) * 2019-11-12 2022-12-23 广西师范大学 一种酶法制备罗汉果苷iv和苷v的方法
CN113106114B (zh) * 2020-01-13 2024-04-12 中国科学院分子植物科学卓越创新中心 调控里氏木霉蛋白表达效率的因子、调控方法及应用
WO2021175751A1 (fr) * 2020-03-05 2021-09-10 Firmenich Sa 11-oxo-cucurbitanes et leur utilisation en tant que modificateurs d'arôme
MX2022011627A (es) * 2020-03-17 2022-12-15 Coca Cola Co Nuevo sistema y métodos de producción de mogrósidos.
CA3177183A1 (fr) * 2020-05-13 2021-11-18 Ginkgo Bioworks, Inc. Biosynthese de mogrosides
CN112626094A (zh) * 2021-01-15 2021-04-09 中国水产科学研究院黄海水产研究所 环糊精葡萄糖基转移酶的基因、氨基酸序列和应用
CN113429451B (zh) * 2021-05-31 2022-02-08 湖南华诚生物资源股份有限公司 一种罗汉果酸酰化衍生物及其制备方法
WO2023278226A1 (fr) * 2021-06-29 2023-01-05 Firmenich Incorporated Composés mogrosides et leur utilisation comestible
CN113481275A (zh) * 2021-07-23 2021-10-08 湖南华诚生物资源股份有限公司 一种酶催化半合成制备罗汉果赛门苷的方法
CN113584110A (zh) * 2021-08-11 2021-11-02 河北维达康生物科技有限公司 一种以罗汉果醇为底物生物合成罗汉果糖苷v的工程菌株的构建及其应用
CN114946910A (zh) * 2022-03-31 2022-08-30 广西朗盛食品科技有限公司 一种低糖红豆蛋黄酥及其制备方法
WO2023225459A2 (fr) 2022-05-14 2023-11-23 Novozymes A/S Compositions et procédés de prévention, de traitement, de suppression et/ou d'élimination d'infestations et d'infections phytopathogènes

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6468576B1 (en) 2000-06-23 2002-10-22 Nestec S.A. Frozen slush liquid concentrate and method of making same
US7939059B2 (en) 2001-12-10 2011-05-10 California Institute Of Technology Method for the generation of antigen-specific lymphocytes
CN103275058B (zh) 2003-08-06 2016-02-24 西诺米克斯公司 调味剂、味道调节剂、促味剂、味觉增强剂、鲜味剂或甜味剂和/或增强剂及其用途
JP4734346B2 (ja) 2005-02-04 2011-07-27 セノミックス インコーポレイテッド 連結ヘテロアリール部分を含む化合物、ならびに食用組成物のための新規なうまみフレーバー改変剤、味物質および味覚増強剤としての使用
EP1879471B1 (fr) 2005-03-22 2014-12-31 Bio-Soluble Solutions JV, LLC Concentres de composition aromatisante
AR055329A1 (es) 2005-06-15 2007-08-15 Senomyx Inc Amidas bis-aromaticas y sus usos como modificadores de sabor dulce, saborizantes, y realzadores de sabor
EP3235811B1 (fr) 2006-04-21 2018-07-25 Senomyx, Inc. Procédé de production d'amides oxaliques
DK2024504T4 (da) 2006-05-26 2023-02-27 Amyris Inc Fremstilling af isoprenoider
US8367395B2 (en) 2006-09-28 2013-02-05 Dsm Ip Assets B.V. Production of sterols in oleaginous yeast and fungi
US7928111B2 (en) 2007-06-08 2011-04-19 Senomyx, Inc. Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
US20110027413A1 (en) 2007-08-17 2011-02-03 Zhonghua Jia Novel Sweetener ISO-Mogroside V
WO2009042070A2 (fr) 2007-09-20 2009-04-02 Amyris Biotechnologies, Inc. Production d'isoprénoïdes
WO2009100333A2 (fr) 2008-02-06 2009-08-13 Senomyx, Inc. Compositions d’édulcorant et leurs procédés de fabrication
TWI429404B (zh) 2008-03-03 2014-03-11 Senomyx Inc 異山梨醇衍生物及彼等作為風味改良劑、促味劑及促味增強劑之用途
MY153622A (en) 2008-07-31 2015-02-27 Senomyx Inc Processes and intermediates for making sweet taste enhancers
US8609173B2 (en) 2008-07-31 2013-12-17 Senomyx Inc. Compositions comprising sweetness enhancers and methods of making them
US8481286B2 (en) 2008-08-12 2013-07-09 Allylix, Inc. Method for production of isoprenoid compounds
BR122018010313B1 (pt) 2009-04-02 2019-04-24 Amyris, Inc. Métodos de estabilização e de hidrogenação para olefinas micróbio-derivadas
MX2011012765A (es) 2009-06-01 2012-02-01 Amyris Inc Metodo para generar un microbio geneticamente modificado.
CN102666837A (zh) 2009-11-23 2012-09-12 纽塞利斯公司 使用酵母产生角鲨烯的方法和组合物
EP4108668A1 (fr) 2010-03-12 2022-12-28 PureCircle USA Inc. Glycosides de stéviol de grande pureté
BR112012025167B1 (pt) 2010-04-02 2024-01-09 Firmenich Incorporated Modificador de sabor doce
WO2011146837A1 (fr) 2010-05-21 2011-11-24 Amyris, Inc. Compositions à base de squalane et d'isosqualane et leurs procédés de fabrication
RU2576451C2 (ru) 2010-08-12 2016-03-10 Синомикс, Инк. Способ улучшения стабильности усилителей сладкого вкуса и композиция, содержащая стабилизированный усилитель сладкого вкуса
MY165612A (en) 2010-11-05 2018-04-18 Senomyx Inc Compounds useful as modulators of trpm8
US8962698B2 (en) * 2011-01-28 2015-02-24 Tate & Lyle Ingredients Americas Llc Rebaudioside-mogroside V blends
EP2670846B1 (fr) 2011-02-02 2015-08-19 Amyris, Inc. Procédés de développement de variants de terpène synthase
ES2607647T3 (es) 2011-08-12 2017-04-03 Senomyx, Inc. Modificador del sabor dulce
AU2012335091B2 (en) 2011-11-09 2016-06-16 Amyris, Inc. Production of acetyl-coenzyme a derived isoprenoids
US9920349B2 (en) * 2011-11-23 2018-03-20 Evolva Sa Methods and materials for enzymatic synthesis of mogroside compounds
PL3009010T3 (pl) 2011-12-19 2020-10-19 Purecircle Sdn Bhd Sposoby oczyszczania glikozydów stewiolowych
AU2013299859B2 (en) 2012-08-06 2017-06-15 Firmenich Incorporated Sweet flavor modifier
AU2013304001B2 (en) 2012-08-17 2019-01-03 Evolva Sa Increased production of terpenes and terpenoids
EP2929043A1 (fr) * 2012-12-04 2015-10-14 Evolva SA Procédés et matériels pour la biosynthèse de composés mogrosides
JO3155B1 (ar) 2013-02-19 2017-09-20 Senomyx Inc معدِّل نكهة حلوة
US9840471B2 (en) 2013-02-19 2017-12-12 Senomyx, Inc. Compounds useful as modulators of TRPM8
US9410214B2 (en) 2013-03-15 2016-08-09 Amyris, Inc. Use of phosphoketolase and phosphotransacetylase for production of acetyl-coenzyme A derived compounds
GB201309077D0 (en) 2013-03-15 2013-07-03 Tate & Lyle Ingredients Improved sweetener
EP3099186B1 (fr) 2013-12-05 2021-05-19 AnalytiCon Discovery GmbH Nouveaux glycosides triterpéniques utilisés comme édulcorants ou renforçateurs de goût sucré
US20180020709A1 (en) 2014-04-16 2018-01-25 Purecircle Usa Inc. Rebaudioside m biosynthetic production and recovery methods
CN103923152B (zh) 2014-05-08 2015-11-04 青岛润德生物科技有限公司 一种罗汉果甙v的提取方法
CN107109377A (zh) * 2014-09-11 2017-08-29 以色列国家农业和农村发展农业研究组织沃尔坎尼中心 生产罗汉果苷的方法和包含其的组合物及其用途
CA2963300C (fr) * 2014-10-01 2024-04-30 Evolva Sa Procedes et matieres pour la biosynthese de composes mogrosides
WO2016060276A1 (fr) * 2014-10-17 2016-04-21 サントリーホールディングス株式会社 Mogrol glycosyltransférase et gène codant pour celle-ci
US11339128B2 (en) 2014-11-07 2022-05-24 Firmenich Incorporated Substituted 4-amino-5-(cyclohexyloxy)quinoline-3-carboxylic acids as sweet flavor modifiers
MX2017010311A (es) 2015-02-10 2017-12-14 Purecircle Usa Inc Metodos de produccion y recuperacion de rebaudiosido m biosintetico.
CN105039274A (zh) 2015-07-13 2015-11-11 中国农业科学院蔬菜花卉研究所 参与西瓜葫芦素e合成的基因簇及其应用
CA2998134A1 (fr) 2015-09-08 2017-03-16 Viewpoint Therapeutics, Inc. Composes et formulations pour traiter les maladies ophthalmiques
EP3368542B1 (fr) * 2015-10-29 2022-06-22 Firmenich Incorporated Édulcorants à intensité élevée
WO2017172766A1 (fr) 2016-03-28 2017-10-05 The Coca-Cola Company Amélioration de la saveur sucrée et de la saveur d'édulcorants de glycosides de stéviol ou de mogrosides avec des flavonoïdes
AU2017246876B2 (en) 2016-04-06 2021-09-23 The Coca-Cola Company Sweetness and taste improvement of steviol glycoside or mogroside sweeteners
EP3502265B1 (fr) 2016-07-19 2020-12-02 Suntory Holdings Limited Procédé de production de mogrol ou de mogrol glycoside
WO2018200663A1 (fr) * 2017-04-25 2018-11-01 The Coca-Cola Company Amélioration de la sucrosité et du goût d'édulcorants à base de glycoside de stéviol et de mogroside avec des dihydrochalcones
EP3638804A1 (fr) 2017-06-15 2020-04-22 Evolva SA Production de composés à base de mogroside dans des hôtes de recombinaison

Also Published As

Publication number Publication date
JP2023052703A (ja) 2023-04-11
EP3615679A2 (fr) 2020-03-04
EP3615679A4 (fr) 2021-02-17
PH12019502456A1 (en) 2020-07-20
WO2018204483A2 (fr) 2018-11-08
RU2767792C2 (ru) 2022-03-21
BR112019023104A2 (pt) 2020-11-03
MX2019012940A (es) 2019-12-16
TW201843304A (zh) 2018-12-16
JP2020518264A (ja) 2020-06-25
JP7285786B2 (ja) 2023-06-02
RU2019138986A (ru) 2021-06-03
WO2018204483A3 (fr) 2018-12-20
CN111108213A (zh) 2020-05-05
US20190071705A1 (en) 2019-03-07
RU2019138986A3 (fr) 2021-06-03
MX2023003744A (es) 2023-04-24
US11060124B2 (en) 2021-07-13
US20210324439A1 (en) 2021-10-21

Similar Documents

Publication Publication Date Title
SG11201910136RA (en) Methods for making high intensity sweeteners
SG11201909949XA (en) Targeted immunotolerance
SG11201900438WA (en) Tree-type coding for video coding
SG11201909777YA (en) Modulatory polynucleotides
SG11201909541WA (en) Chimeric antibody/t-cell receptor constructs and uses thereof
SG11201910085UA (en) Atropine pharmaceutical compositions
SG11201901206SA (en) Trimer stabilizing hiv envelope protein mutations
SG11201807252QA (en) Anti-lag-3 antibodies
SG11201906395PA (en) Blockchain based data processing method and device
SG11201808831TA (en) Transgenic t cell and chimeric antigen receptor t cell compositions and related methods
SG11201805493YA (en) Binding members with altered diversity scaffold domains
SG11201907210YA (en) Policy communication via control plane signaling
SG11201804729RA (en) Methods and compositions for treating a serpinc1-associated disorder
SG11201806863WA (en) Tetracyclic pyridone compounds as antivirals
SG11201909203WA (en) Tissue selective transgene expression
SG11201900634VA (en) Chimeric antigen receptor
SG11201909728XA (en) Constructs specifically recognizing glypican 3 and uses thereof
SG11201806496SA (en) Antigen binding proteins that bind pd-l1
SG11201806639VA (en) New streptococcal proteases
SG11201810525XA (en) Anti-gitr antibodies and uses thereof
SG11201905508VA (en) Hsd17b13 variants and uses thereof
SG11201906552WA (en) TGF-ß DECOY RECEPTOR
SG11201807325UA (en) Optimizing range of aircraft docking system
SG11201901228QA (en) Chromatography method for quantifying a non-ionic surfactant in a composition comprising the non-ionic surfactant and a polypeptide
SG11201810157QA (en) Variant flavivirus envelope sequences and uses thereof