SG11201706767RA - Materials and methods for treatment of hemoglobinopathies - Google Patents

Materials and methods for treatment of hemoglobinopathies

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Publication number
SG11201706767RA
SG11201706767RA SG11201706767RA SG11201706767RA SG11201706767RA SG 11201706767R A SG11201706767R A SG 11201706767RA SG 11201706767R A SG11201706767R A SG 11201706767RA SG 11201706767R A SG11201706767R A SG 11201706767RA SG 11201706767R A SG11201706767R A SG 11201706767RA
Authority
SG
Singapore
Prior art keywords
hemoglobinopathies
treatment
materials
methods
Prior art date
Application number
SG11201706767RA
Other languages
English (en)
Inventor
Matthew Hebden Porteus
Thomas James Cradick
Gang Bao
Ciaran M Lee
Original Assignee
Crispr Therapeutics Ag
Georgia Tech Res Inst
Univ Rice William M
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crispr Therapeutics Ag, Georgia Tech Res Inst, Univ Rice William M filed Critical Crispr Therapeutics Ag
Publication of SG11201706767RA publication Critical patent/SG11201706767RA/en

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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • A61K38/41—Porphyrin- or corrin-ring-containing peptides
    • A61K38/42—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
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    • C12N15/09—Recombinant DNA-technology
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/0602—Vertebrate cells
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPRs]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/73—Hydrolases (EC 3.)
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    • C12N2510/00—Genetically modified cells

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  • General Engineering & Computer Science (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Plant Pathology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Gynecology & Obstetrics (AREA)
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  • Diabetes (AREA)
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SG11201706767RA 2015-02-23 2016-02-23 Materials and methods for treatment of hemoglobinopathies SG11201706767RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562119754P 2015-02-23 2015-02-23
PCT/IB2016/000282 WO2016135558A2 (fr) 2015-02-23 2016-02-23 Matériels et méthodes pour le traitement des hémoglobinopathies

Publications (1)

Publication Number Publication Date
SG11201706767RA true SG11201706767RA (en) 2017-09-28

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ID=55795007

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201706767RA SG11201706767RA (en) 2015-02-23 2016-02-23 Materials and methods for treatment of hemoglobinopathies
SG11201706766WA SG11201706766WA (en) 2015-02-23 2016-02-23 Materials and methods for treatment of hemoglobinopathies

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201706766WA SG11201706766WA (en) 2015-02-23 2016-02-23 Materials and methods for treatment of hemoglobinopathies

Country Status (8)

Country Link
US (3) US10738305B2 (fr)
EP (2) EP3262172A2 (fr)
CN (2) CN107532168A (fr)
AU (2) AU2016225178B2 (fr)
BR (2) BR112017017812A2 (fr)
CA (2) CA2977455A1 (fr)
SG (2) SG11201706767RA (fr)
WO (2) WO2016135558A2 (fr)

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CA2977455A1 (fr) 2019-09-01
US20180021413A1 (en) 2018-01-25
US20210009998A1 (en) 2021-01-14
CN107532168A (zh) 2018-01-02
CN107532182A (zh) 2018-01-02
WO2016135558A3 (fr) 2016-10-20
WO2016135558A2 (fr) 2016-09-01
WO2016135557A3 (fr) 2016-10-20
AU2016225178B2 (en) 2022-05-05
WO2016135557A2 (fr) 2016-09-01
CA2977447A1 (fr) 2016-09-01
SG11201706766WA (en) 2017-09-28
AU2016225178A1 (en) 2017-08-31
BR112017017812A2 (pt) 2018-04-10
BR112017017810A2 (pt) 2018-04-10
US20180030438A1 (en) 2018-02-01
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AU2016225179B2 (en) 2022-05-05
AU2016225178A9 (en) 2022-05-05
AU2016225179C1 (en) 2022-11-03
EP3262172A2 (fr) 2018-01-03
US10738305B2 (en) 2020-08-11
AU2016225179A1 (en) 2017-08-31
US20210317450A9 (en) 2021-10-14

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