SG11201702934TA - Compositions of adenosine deaminase-2 (ada2), variants thereof and methods of using same - Google Patents

Compositions of adenosine deaminase-2 (ada2), variants thereof and methods of using same

Info

Publication number
SG11201702934TA
SG11201702934TA SG11201702934TA SG11201702934TA SG11201702934TA SG 11201702934T A SG11201702934T A SG 11201702934TA SG 11201702934T A SG11201702934T A SG 11201702934TA SG 11201702934T A SG11201702934T A SG 11201702934TA SG 11201702934T A SG11201702934T A SG 11201702934TA
Authority
SG
Singapore
Prior art keywords
ada2
variants
compositions
methods
same
Prior art date
Application number
SG11201702934TA
Other languages
English (en)
Inventor
Christopher D Thanos
Lin Wang
Michael H Shepard
Original Assignee
Halozyme Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Halozyme Inc filed Critical Halozyme Inc
Publication of SG11201702934TA publication Critical patent/SG11201702934TA/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/04—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in cyclic amidines (3.5.4)
    • C12Y305/04004—Adenosine deaminase (3.5.4.4)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11201702934TA 2014-10-14 2015-10-14 Compositions of adenosine deaminase-2 (ada2), variants thereof and methods of using same SG11201702934TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462063936P 2014-10-14 2014-10-14
PCT/US2015/055613 WO2016061286A2 (fr) 2014-10-14 2015-10-14 Compositions d'adénosine désaminase-2 (ada2), variants de cette dernière et leurs procédés d'utilisation

Publications (1)

Publication Number Publication Date
SG11201702934TA true SG11201702934TA (en) 2017-05-30

Family

ID=54601993

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201702934TA SG11201702934TA (en) 2014-10-14 2015-10-14 Compositions of adenosine deaminase-2 (ada2), variants thereof and methods of using same

Country Status (16)

Country Link
US (3) US9969998B2 (fr)
EP (1) EP3207130B1 (fr)
JP (1) JP6625627B2 (fr)
KR (1) KR102122463B1 (fr)
CN (1) CN108064282A (fr)
AU (2) AU2015332533B2 (fr)
BR (1) BR112017007765B1 (fr)
CA (3) CA3203273A1 (fr)
DK (1) DK3207130T3 (fr)
EA (1) EA201700181A1 (fr)
ES (1) ES2753391T3 (fr)
IL (1) IL251527B (fr)
NZ (2) NZ746680A (fr)
PL (1) PL3207130T3 (fr)
SG (1) SG11201702934TA (fr)
WO (1) WO2016061286A2 (fr)

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CA3126536A1 (fr) 2016-04-21
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US20230203470A1 (en) 2023-06-29
JP2017532045A (ja) 2017-11-02
ES2753391T3 (es) 2020-04-08
AU2018236742A1 (en) 2018-10-18
KR102122463B1 (ko) 2020-06-15
US9969998B2 (en) 2018-05-15
NZ746680A (en) 2020-07-31
US20170166878A9 (en) 2017-06-15
CA3203273A1 (fr) 2016-04-21
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IL251527A0 (en) 2017-05-29
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JP6625627B2 (ja) 2019-12-25
US20180216095A1 (en) 2018-08-02
WO2016061286A2 (fr) 2016-04-21
WO2016061286A3 (fr) 2016-07-07
WO2016061286A9 (fr) 2016-08-25
BR112017007765B1 (pt) 2023-10-03
IL251527B (en) 2020-07-30
CA2964317A1 (fr) 2016-04-21
US20160272960A1 (en) 2016-09-22
US11584923B2 (en) 2023-02-21
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