SG11201507429TA - Il-22 polypeptides and il-22 fc fusion proteins and methods of use - Google Patents
Il-22 polypeptides and il-22 fc fusion proteins and methods of useInfo
- Publication number
- SG11201507429TA SG11201507429TA SG11201507429TA SG11201507429TA SG11201507429TA SG 11201507429T A SG11201507429T A SG 11201507429TA SG 11201507429T A SG11201507429T A SG 11201507429TA SG 11201507429T A SG11201507429T A SG 11201507429TA SG 11201507429T A SG11201507429T A SG 11201507429TA
- Authority
- SG
- Singapore
- Prior art keywords
- polypeptides
- methods
- fusion proteins
- fusion
- proteins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Urology & Nephrology (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361800148P | 2013-03-15 | 2013-03-15 | |
US201361801144P | 2013-03-15 | 2013-03-15 | |
US201361800795P | 2013-03-15 | 2013-03-15 | |
US201361821062P | 2013-05-08 | 2013-05-08 | |
US201361860176P | 2013-07-30 | 2013-07-30 | |
PCT/US2014/029652 WO2014145016A2 (en) | 2013-03-15 | 2014-03-14 | Il-22 polypeptides and il-22 fc fusion proteins and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201507429TA true SG11201507429TA (en) | 2015-10-29 |
Family
ID=50942310
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201808523RA SG10201808523RA (en) | 2013-03-15 | 2014-03-14 | Il-22 polypeptides and il-22 fc fusion proteins and methods of use |
SG11201507429TA SG11201507429TA (en) | 2013-03-15 | 2014-03-14 | Il-22 polypeptides and il-22 fc fusion proteins and methods of use |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201808523RA SG10201808523RA (en) | 2013-03-15 | 2014-03-14 | Il-22 polypeptides and il-22 fc fusion proteins and methods of use |
Country Status (29)
Country | Link |
---|---|
US (12) | US10160793B2 (de) |
EP (2) | EP3385277A1 (de) |
JP (3) | JP6456356B2 (de) |
KR (1) | KR102426481B1 (de) |
CN (1) | CN105143252A (de) |
AU (3) | AU2014233494B2 (de) |
BR (1) | BR112015023140A8 (de) |
CA (1) | CA2903587C (de) |
CL (1) | CL2015002654A1 (de) |
DK (1) | DK2970422T3 (de) |
EA (1) | EA035645B1 (de) |
ES (1) | ES2676023T3 (de) |
HK (1) | HK1218424A1 (de) |
HR (1) | HRP20181090T1 (de) |
HU (1) | HUE039291T2 (de) |
LT (1) | LT2970422T (de) |
MX (2) | MX368005B (de) |
PE (2) | PE20151673A1 (de) |
PH (2) | PH12015502125B1 (de) |
PL (1) | PL2970422T3 (de) |
PT (1) | PT2970422T (de) |
RS (1) | RS57393B1 (de) |
SG (2) | SG10201808523RA (de) |
SI (1) | SI2970422T1 (de) |
TR (1) | TR201809571T4 (de) |
TW (2) | TWI772250B (de) |
UA (1) | UA118843C2 (de) |
WO (1) | WO2014145016A2 (de) |
ZA (1) | ZA201506297B (de) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111757751A (zh) * | 2018-02-21 | 2020-10-09 | 豪夫迈·罗氏有限公司 | 用于使用IL-22 Fc融合蛋白的治疗的剂量方案 |
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CN101361968B (zh) | 2007-08-06 | 2011-08-03 | 健能隆医药技术(上海)有限公司 | 白介素-22在治疗脂肪肝中的应用 |
US9550819B2 (en) | 2012-03-27 | 2017-01-24 | Ngm Biopharmaceuticals, Inc. | Compositions and methods of use for treating metabolic disorders |
US9161966B2 (en) | 2013-01-30 | 2015-10-20 | Ngm Biopharmaceuticals, Inc. | GDF15 mutein polypeptides |
EP2950807B1 (de) | 2013-01-30 | 2018-03-28 | NGM Biopharmaceuticals, Inc. | Zusammensetzungen und verfahren zur verwendung bei der behandlung von stoffwechselerkrankungen |
US9580486B2 (en) * | 2013-03-14 | 2017-02-28 | Amgen Inc. | Interleukin-2 muteins for the expansion of T-regulatory cells |
KR102426481B1 (ko) | 2013-03-15 | 2022-07-27 | 제넨테크, 인크. | IL-22 폴리펩티드 및 IL-22 Fc 융합 단백질 및 사용 방법 |
CN104623639A (zh) | 2013-11-07 | 2015-05-20 | 健能隆医药技术(上海)有限公司 | 白介素22二聚体在制备治疗胰腺炎药物中的应用 |
CA2929843A1 (en) | 2013-11-07 | 2015-05-14 | Memorial Sloan-Kettering Cancer Center | Methods of use for il-22 in the treatment of gastrointestinal graft vs. host disease |
CN104623637A (zh) | 2013-11-07 | 2015-05-20 | 健能隆医药技术(上海)有限公司 | Il-22二聚体在制备静脉注射药物中的应用 |
TN2016000578A1 (en) | 2014-07-30 | 2018-04-04 | Ngm Biopharmaceuticals Inc | Compositions and methods of use for treating metabolic disorders |
MD20170035A2 (ro) | 2014-10-31 | 2017-09-30 | Ngm Biopharmaceuticals Inc | Compoziţii şi metode de utilizare pentru tratamentul tulburărilor metabolice |
US11566082B2 (en) | 2014-11-17 | 2023-01-31 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
WO2016108130A1 (en) * | 2014-12-30 | 2016-07-07 | Sun Pharmaceutical Industries Limited | Topical pharmaceutical compositions comprising nebivolol for the treatment of diabetic wounds |
TN2017000432A1 (en) | 2015-04-10 | 2019-04-12 | Amgen Inc | Interleukin-2 muteins for the expansion of t-regulatory cells |
CN106317225A (zh) * | 2015-06-28 | 2017-01-11 | 复旦大学 | 具有靶向性长效白细胞介素22融合蛋白及其制备方法和用途 |
PE20180797A1 (es) * | 2015-07-16 | 2018-05-09 | Philogen Spa | Inmunoconjugados de il22 |
SG10201913625XA (en) | 2015-08-07 | 2020-03-30 | Imaginab Inc | Antigen binding constructs to target molecules |
EP3167892A1 (de) | 2015-11-10 | 2017-05-17 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Verfahren und pharmazeutische zusammensetzungen zur vorbeugung oder behandlung von entzündlichen darmerkrankungen |
CN109715206B (zh) | 2016-03-31 | 2023-11-07 | 恩格姆生物制药公司 | 结合蛋白及其使用方法 |
CN109328069B (zh) * | 2016-04-15 | 2023-09-01 | 亿一生物医药开发(上海)有限公司 | Il-22在治疗坏死性小肠结肠炎中的用途 |
WO2017191817A1 (ja) * | 2016-05-02 | 2017-11-09 | 味の素株式会社 | アジド基含有Fcタンパク質 |
US10889615B2 (en) | 2016-05-11 | 2021-01-12 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
CN109071613A (zh) | 2016-05-11 | 2018-12-21 | 通用电气医疗集团生物工艺研发股份公司 | 分离基质 |
US10654887B2 (en) | 2016-05-11 | 2020-05-19 | Ge Healthcare Bio-Process R&D Ab | Separation matrix |
EP3455240A1 (de) | 2016-05-11 | 2019-03-20 | GE Healthcare BioProcess R&D AB | Verfahren zum speichern einer trennmatrix |
US10730908B2 (en) | 2016-05-11 | 2020-08-04 | Ge Healthcare Bioprocess R&D Ab | Separation method |
US10703774B2 (en) | 2016-09-30 | 2020-07-07 | Ge Healthcare Bioprocess R&D Ab | Separation method |
US11753438B2 (en) | 2016-05-11 | 2023-09-12 | Cytiva Bioprocess R&D Ab | Method of cleaning and/or sanitizing a separation matrix |
CN108239151B (zh) * | 2016-12-23 | 2020-07-03 | 海门晟斯生物制药有限公司 | 重组单链人FVIII-Fc融合蛋白及其应用 |
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US11964002B2 (en) | 2017-02-28 | 2024-04-23 | Vib Vzw | Means and methods for oral protein delivery |
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JP7349995B2 (ja) * | 2018-01-26 | 2023-09-25 | ジェネンテック, インコーポレイテッド | IL-22 Fc融合タンパク質及び使用方法 |
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US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
CN112292396A (zh) | 2018-06-05 | 2021-01-29 | 生物蛋白有限公司 | 抗il-22抗体,抗体片段,其免疫结合物及其用途 |
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KR20220041146A (ko) * | 2019-07-26 | 2022-03-31 | 제넨테크, 인크. | IL-22 Fc 융합 단백질들을 사용한, 이식편 대 숙주 질환 (GVHD)의 예방 또는 치료를 위한 투약 |
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TW202122117A (zh) | 2019-09-06 | 2021-06-16 | 美商席達拉醫療有限公司 | 用於治療病毒感染之組合物及方法 |
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CN112618698B (zh) * | 2019-10-08 | 2021-10-08 | 北京东方百泰生物科技股份有限公司 | 一种人白细胞介素10-Fc融合蛋白的注射制剂 |
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- 2018-11-20 US US16/196,741 patent/US20190177386A1/en not_active Abandoned
- 2018-11-20 US US16/196,823 patent/US11136365B2/en active Active
- 2018-11-20 US US16/196,936 patent/US11130791B2/en active Active
- 2018-11-20 US US16/196,743 patent/US20190177387A1/en not_active Abandoned
- 2018-11-20 US US16/196,829 patent/US11155591B2/en active Active
-
2020
- 2020-04-02 PH PH12020550205A patent/PH12020550205A1/en unknown
- 2020-07-15 AU AU2020205284A patent/AU2020205284A1/en not_active Abandoned
-
2021
- 2021-12-10 JP JP2021200466A patent/JP2022046520A/ja active Pending
-
2022
- 2022-04-15 US US17/721,970 patent/US20230063741A1/en not_active Abandoned
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111757751A (zh) * | 2018-02-21 | 2020-10-09 | 豪夫迈·罗氏有限公司 | 用于使用IL-22 Fc融合蛋白的治疗的剂量方案 |
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