SG11201403443WA - Expression vector element combinations, novel production cell generation methods and their use for the recombinant production of polypeptides - Google Patents
Expression vector element combinations, novel production cell generation methods and their use for the recombinant production of polypeptidesInfo
- Publication number
- SG11201403443WA SG11201403443WA SG11201403443WA SG11201403443WA SG11201403443WA SG 11201403443W A SG11201403443W A SG 11201403443WA SG 11201403443W A SG11201403443W A SG 11201403443WA SG 11201403443W A SG11201403443W A SG 11201403443WA SG 11201403443W A SG11201403443W A SG 11201403443WA
- Authority
- SG
- Singapore
- Prior art keywords
- polypeptides
- expression vector
- vector element
- cell generation
- generation methods
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
- C07K16/2854—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/36—Vector systems having a special element relevant for transcription being a transcription termination element
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11195361 | 2011-12-22 | ||
| PCT/EP2012/076203 WO2013092743A2 (en) | 2011-12-22 | 2012-12-19 | Expression vector element combinations, novel production cell generation methods and their use for the recombinant production of polypeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201403443WA true SG11201403443WA (en) | 2014-07-30 |
Family
ID=47504950
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201403443WA SG11201403443WA (en) | 2011-12-22 | 2012-12-19 | Expression vector element combinations, novel production cell generation methods and their use for the recombinant production of polypeptides |
| SG10201700169PA SG10201700169PA (en) | 2011-12-22 | 2012-12-19 | Expression vector element combinations, novel production cell generation methods and their use for the recombinant production of polypeptides |
| SG10201900915WA SG10201900915WA (en) | 2011-12-22 | 2012-12-19 | Expression vector element combinations, novel production cell generation methods and their use for the recombinant production of polypeptides |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201700169PA SG10201700169PA (en) | 2011-12-22 | 2012-12-19 | Expression vector element combinations, novel production cell generation methods and their use for the recombinant production of polypeptides |
| SG10201900915WA SG10201900915WA (en) | 2011-12-22 | 2012-12-19 | Expression vector element combinations, novel production cell generation methods and their use for the recombinant production of polypeptides |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20160208284A1 (ja) |
| EP (2) | EP3354660A1 (ja) |
| JP (4) | JP6096802B2 (ja) |
| KR (4) | KR102229491B1 (ja) |
| CN (4) | CN113881702A (ja) |
| BR (1) | BR112014014239B1 (ja) |
| CA (2) | CA3149402A1 (ja) |
| ES (1) | ES2930215T3 (ja) |
| HK (1) | HK1200848A1 (ja) |
| HR (1) | HRP20221383T1 (ja) |
| MX (2) | MX355624B (ja) |
| PL (1) | PL2794651T3 (ja) |
| RU (2) | RU2756910C2 (ja) |
| SG (3) | SG11201403443WA (ja) |
| WO (1) | WO2013092743A2 (ja) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
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| MX355624B (es) * | 2011-12-22 | 2018-04-25 | Hoffmann La Roche | Combinaciones de elementos de vector de expresion, metodos novedosos de generacion de celulas de produccion y su uso para la produccion recombinante de polipeptidos. |
| EP3059319A4 (en) * | 2013-10-07 | 2017-04-26 | Prestige Biopharma Pte. Ltd. | Bicistronic expression vector for antibody expression and method for producing antibody using same |
| CN105255867A (zh) * | 2015-10-19 | 2016-01-20 | 北京益生合生物科技有限公司 | 一种防止启动子在传代培养中逐渐灭活的基因序列及其应用 |
| US11098310B2 (en) | 2016-01-27 | 2021-08-24 | Just-Evotec Biologics, Inc. | Expression from transposon-based vectors and uses |
| JP6937309B2 (ja) | 2016-01-27 | 2021-09-22 | ジャスト−エヴォテック バイオロジックス、インコーポレイテッド | ハイブリッドプロモーターおよびその使用 |
| US11261462B2 (en) | 2016-01-27 | 2022-03-01 | Just-Evotec Biologics, Inc. | Inducible expression from transposon-based vectors and uses |
| WO2018075736A1 (en) | 2016-10-20 | 2018-04-26 | Sangamo Therapeutics, Inc. | Methods and compositions for the treatment of fabry disease |
| KR102607655B1 (ko) * | 2017-05-19 | 2023-11-28 | 카운슬 오브 사이언티픽 앤드 인더스트리얼 리서치 | 리폴딩된 재조합 인간화 라니비주맙의 제조 방법 |
| JP7081139B2 (ja) * | 2017-12-20 | 2022-06-07 | 東ソー株式会社 | 新規プロモーターおよびそれを含む発現ベクター |
| BR112021005115A2 (pt) * | 2018-09-20 | 2021-06-15 | Sanofi | métodos e composições de clonagem universal baseada em íntron |
| JP7208380B2 (ja) * | 2018-10-26 | 2023-01-18 | エフ．ホフマン－ラ ロシュ アーゲー | リコンビナーゼ媒介性カセット交換を使用した多重特異性抗体スクリーニング法 |
| CN117043194A (zh) | 2021-01-29 | 2023-11-10 | 默沙东有限责任公司 | 程序性死亡受体1（pd-1）抗体的组合物以及获得所述组合物的方法 |
| KR102640929B1 (ko) | 2023-06-02 | 2024-02-27 | (주) 멥스젠 | 미세생체조직시스템 형성 장치 |
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