HK1200848A1 - Expression vector element combinations, novel production cell generation methods and their use for the recombinant production of polypeptides - Google Patents
Expression vector element combinations, novel production cell generation methods and their use for the recombinant production of polypeptidesInfo
- Publication number
- HK1200848A1 HK1200848A1 HK15101213.2A HK15101213A HK1200848A1 HK 1200848 A1 HK1200848 A1 HK 1200848A1 HK 15101213 A HK15101213 A HK 15101213A HK 1200848 A1 HK1200848 A1 HK 1200848A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- polypeptides
- expression vector
- vector element
- cell generation
- generation methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
- C07K16/2854—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/36—Vector systems having a special element relevant for transcription being a transcription termination element
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11195361 | 2011-12-22 | ||
PCT/EP2012/076203 WO2013092743A2 (en) | 2011-12-22 | 2012-12-19 | Expression vector element combinations, novel production cell generation methods and their use for the recombinant production of polypeptides |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1200848A1 true HK1200848A1 (en) | 2015-08-14 |
Family
ID=47504950
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15101213.2A HK1200848A1 (en) | 2011-12-22 | 2015-02-04 | Expression vector element combinations, novel production cell generation methods and their use for the recombinant production of polypeptides |
Country Status (14)
Country | Link |
---|---|
US (2) | US20160208284A1 (ja) |
EP (2) | EP2794651B1 (ja) |
JP (4) | JP6096802B2 (ja) |
KR (4) | KR102229491B1 (ja) |
CN (4) | CN107119073A (ja) |
CA (2) | CA2854249C (ja) |
ES (1) | ES2930215T3 (ja) |
HK (1) | HK1200848A1 (ja) |
HR (1) | HRP20221383T1 (ja) |
MX (2) | MX370481B (ja) |
PL (1) | PL2794651T3 (ja) |
RU (2) | RU2756910C2 (ja) |
SG (3) | SG10201700169PA (ja) |
WO (1) | WO2013092743A2 (ja) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
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JP6343011B2 (ja) * | 2013-10-07 | 2018-06-13 | プレステージ バイオファーマ プライベート リミテッド | 抗体発現用バイシストロニック発現ベクター及びそれを用いた抗体の生産方法 |
CN105255867A (zh) * | 2015-10-19 | 2016-01-20 | 北京益生合生物科技有限公司 | 一种防止启动子在传代培养中逐渐灭活的基因序列及其应用 |
ES2823173T3 (es) | 2016-01-27 | 2021-05-06 | Just Biotherapeutics Inc | Promotor híbrido y usos del mismo |
US11261462B2 (en) | 2016-01-27 | 2022-03-01 | Just-Evotec Biologics, Inc. | Inducible expression from transposon-based vectors and uses |
US11098310B2 (en) | 2016-01-27 | 2021-08-24 | Just-Evotec Biologics, Inc. | Expression from transposon-based vectors and uses |
AU2017345430A1 (en) | 2016-10-20 | 2019-05-02 | Sangamo Therapeutics, Inc. | Methods and compositions for the treatment of Fabry disease |
EP3624847A1 (en) * | 2017-05-19 | 2020-03-25 | Council of Scientific and Industrial Research | A method for producing refolded recombinant humanized ranibizumab |
JP7081139B2 (ja) * | 2017-12-20 | 2022-06-07 | 東ソー株式会社 | 新規プロモーターおよびそれを含む発現ベクター |
AR124712A1 (es) | 2021-01-29 | 2023-04-26 | Merck Sharp & Dohme | Composiciones de anticuerpos del receptor de muerte programada 1 (pd-1) y métodos para obtener las composiciones de los mismos |
KR102640929B1 (ko) | 2023-06-02 | 2024-02-27 | (주) 멥스젠 | 미세생체조직시스템 형성 장치 |
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2012
- 2012-12-19 SG SG10201700169PA patent/SG10201700169PA/en unknown
- 2012-12-19 RU RU2017140661A patent/RU2756910C2/ru active
- 2012-12-19 CN CN201710324350.7A patent/CN107119073A/zh active Pending
- 2012-12-19 EP EP12810245.6A patent/EP2794651B1/en active Active
- 2012-12-19 CA CA2854249A patent/CA2854249C/en active Active
- 2012-12-19 RU RU2014129727A patent/RU2639519C2/ru active
- 2012-12-19 KR KR1020207007391A patent/KR102229491B1/ko active IP Right Grant
- 2012-12-19 CN CN201280062793.9A patent/CN104011075B/zh active Active
- 2012-12-19 CA CA3149402A patent/CA3149402A1/en active Pending
- 2012-12-19 ES ES12810245T patent/ES2930215T3/es active Active
- 2012-12-19 EP EP18157484.9A patent/EP3354660A1/en active Pending
- 2012-12-19 US US14/367,680 patent/US20160208284A1/en not_active Abandoned
- 2012-12-19 CN CN202111171021.6A patent/CN113896787A/zh active Pending
- 2012-12-19 JP JP2014547983A patent/JP6096802B2/ja active Active
- 2012-12-19 SG SG10201900915WA patent/SG10201900915WA/en unknown
- 2012-12-19 CN CN202111170578.8A patent/CN113881702A/zh active Pending
- 2012-12-19 SG SG11201403443WA patent/SG11201403443WA/en unknown
- 2012-12-19 KR KR1020197034166A patent/KR102166824B1/ko active IP Right Grant
- 2012-12-19 MX MX2017012736A patent/MX370481B/es unknown
- 2012-12-19 PL PL12810245.6T patent/PL2794651T3/pl unknown
- 2012-12-19 WO PCT/EP2012/076203 patent/WO2013092743A2/en active Application Filing
- 2012-12-19 MX MX2014007359A patent/MX355624B/es active IP Right Grant
- 2012-12-19 HR HRP20221383TT patent/HRP20221383T1/hr unknown
- 2012-12-19 KR KR1020217007341A patent/KR102285184B1/ko active IP Right Grant
- 2012-12-19 KR KR1020147016825A patent/KR102048556B1/ko active IP Right Grant
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2015
- 2015-02-04 HK HK15101213.2A patent/HK1200848A1/xx unknown
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2017
- 2017-02-16 JP JP2017026502A patent/JP6417436B2/ja active Active
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2018
- 2018-10-05 JP JP2018189605A patent/JP2019030311A/ja active Pending
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2019
- 2019-12-09 JP JP2019221805A patent/JP7096806B2/ja active Active
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2020
- 2020-07-06 US US16/921,194 patent/US20210024952A1/en active Pending
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