SG11201400770SA - Pyrrolobenzodiazepines as unsymmetrical dimeric pbd compounds for inclusion in targeted conjugates - Google Patents

Pyrrolobenzodiazepines as unsymmetrical dimeric pbd compounds for inclusion in targeted conjugates

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Publication number
SG11201400770SA
SG11201400770SA SG11201400770SA SG11201400770SA SG11201400770SA SG 11201400770S A SG11201400770S A SG 11201400770SA SG 11201400770S A SG11201400770S A SG 11201400770SA SG 11201400770S A SG11201400770S A SG 11201400770SA SG 11201400770S A SG11201400770S A SG 11201400770SA
Authority
SG
Singapore
Prior art keywords
pyrrolobenzodiazepines
inclusion
pbd compounds
targeted conjugates
dimeric pbd
Prior art date
Application number
SG11201400770SA
Other languages
English (en)
Inventor
Philip Wilson Howard
Original Assignee
Spirogen Sarl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spirogen Sarl filed Critical Spirogen Sarl
Publication of SG11201400770SA publication Critical patent/SG11201400770SA/en

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
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SG11201400770SA 2011-09-20 2012-09-20 Pyrrolobenzodiazepines as unsymmetrical dimeric pbd compounds for inclusion in targeted conjugates SG11201400770SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161536669P 2011-09-20 2011-09-20
PCT/EP2012/068506 WO2013041606A1 (en) 2011-09-20 2012-09-20 Pyrrolobenzodiazepines as unsymmetrical dimeric pbd compounds for inclusion in targeted conjugates

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SG11201400770SA true SG11201400770SA (en) 2014-04-28

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CA2849039C (en) 2018-09-18
CA2849039A1 (en) 2013-03-28
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US9399641B2 (en) 2016-07-26
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