US556A
(en)
|
|
1838-01-09 |
|
Machine foe |
US233A
(en)
|
|
1837-06-14 |
|
Improvement in plows |
US5013A
(en)
|
|
1847-03-13 |
|
Improvement in apparatus for the manufacture of malleable iron |
US4447A
(en)
|
|
1846-04-04 |
|
Car- wheel |
US3180193A
(en)
|
1963-02-25 |
1965-04-27 |
Benedict David |
Machines for cutting lengths of strip material
|
US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
US3691016A
(en)
|
1970-04-17 |
1972-09-12 |
Monsanto Co |
Process for the preparation of insoluble enzymes
|
CA1023287A
(en)
|
1972-12-08 |
1977-12-27 |
Boehringer Mannheim G.M.B.H. |
Process for the preparation of carrier-bound proteins
|
US4179337A
(en)
|
1973-07-20 |
1979-12-18 |
Davis Frank F |
Non-immunogenic polypeptides
|
US4195128A
(en)
|
1976-05-03 |
1980-03-25 |
Bayer Aktiengesellschaft |
Polymeric carrier bound ligands
|
US4330440A
(en)
|
1977-02-08 |
1982-05-18 |
Development Finance Corporation Of New Zealand |
Activated matrix and method of activation
|
CA1093991A
(en)
|
1977-02-17 |
1981-01-20 |
Hideo Hirohara |
Enzyme immobilization with pullulan gel
|
US4229537A
(en)
|
1978-02-09 |
1980-10-21 |
New York University |
Preparation of trichloro-s-triazine activated supports for coupling ligands
|
US4263428A
(en)
|
1978-03-24 |
1981-04-21 |
The Regents Of The University Of California |
Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
|
JPS6023084B2
(ja)
|
1979-07-11 |
1985-06-05 |
味の素株式会社 |
代用血液
|
IE52535B1
(en)
|
1981-02-16 |
1987-12-09 |
Ici Plc |
Continuous release pharmaceutical compositions
|
US4475196A
(en)
|
1981-03-06 |
1984-10-02 |
Zor Clair G |
Instrument for locating faults in aircraft passenger reading light and attendant call control system
|
US4447233A
(en)
|
1981-04-10 |
1984-05-08 |
Parker-Hannifin Corporation |
Medication infusion pump
|
US4485045A
(en)
|
1981-07-06 |
1984-11-27 |
Research Corporation |
Synthetic phosphatidyl cholines useful in forming liposomes
|
US4640835A
(en)
|
1981-10-30 |
1987-02-03 |
Nippon Chemiphar Company, Ltd. |
Plasminogen activator derivatives
|
DE3374837D1
(en)
|
1982-02-17 |
1988-01-21 |
Ciba Geigy Ag |
Lipids in the aqueous phase
|
US4439196A
(en)
|
1982-03-18 |
1984-03-27 |
Merck & Co., Inc. |
Osmotic drug delivery system
|
US4447224A
(en)
|
1982-09-20 |
1984-05-08 |
Infusaid Corporation |
Variable flow implantable infusion apparatus
|
US4487603A
(en)
|
1982-11-26 |
1984-12-11 |
Cordis Corporation |
Implantable microinfusion pump system
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
US4486194A
(en)
|
1983-06-08 |
1984-12-04 |
James Ferrara |
Therapeutic device for administering medicaments through the skin
|
US4544545A
(en)
|
1983-06-20 |
1985-10-01 |
Trustees University Of Massachusetts |
Liposomes containing modified cholesterol for organ targeting
|
HUT35524A
(en)
|
1983-08-02 |
1985-07-29 |
Hoechst Ag |
Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance
|
DE3474511D1
(en)
|
1983-11-01 |
1988-11-17 |
Terumo Corp |
Pharmaceutical composition containing urokinase
|
US4496689A
(en)
|
1983-12-27 |
1985-01-29 |
Miles Laboratories, Inc. |
Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
|
US4694778A
(en)
|
1984-05-04 |
1987-09-22 |
Anicon, Inc. |
Chemical vapor deposition wafer boat
|
JPS6147500A
(ja)
|
1984-08-15 |
1986-03-07 |
Res Dev Corp Of Japan |
キメラモノクロ−ナル抗体及びその製造法
|
EP0173494A3
(de)
|
1984-08-27 |
1987-11-25 |
The Board Of Trustees Of The Leland Stanford Junior University |
Chimäre Rezeptoren durch Verbindung und Expression von DNS
|
GB8422238D0
(en)
|
1984-09-03 |
1984-10-10 |
Neuberger M S |
Chimeric proteins
|
US4879231A
(en)
|
1984-10-30 |
1989-11-07 |
Phillips Petroleum Company |
Transformation of yeasts of the genus pichia
|
US4596556A
(en)
|
1985-03-25 |
1986-06-24 |
Bioject, Inc. |
Hypodermic injection apparatus
|
US4751180A
(en)
|
1985-03-28 |
1988-06-14 |
Chiron Corporation |
Expression using fused genes providing for protein product
|
EP0206448B1
(de)
|
1985-06-19 |
1990-11-14 |
Ajinomoto Co., Inc. |
Hämoglobin, das an ein Poly(alkenylenoxid) gebunden ist
|
US4935233A
(en)
|
1985-12-02 |
1990-06-19 |
G. D. Searle And Company |
Covalently linked polypeptide cell modulators
|
WO1987005330A1
(en)
|
1986-03-07 |
1987-09-11 |
Michel Louis Eugene Bergh |
Method for enhancing glycoprotein stability
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
GB8610600D0
(en)
|
1986-04-30 |
1986-06-04 |
Novo Industri As |
Transformation of trichoderma
|
US4791192A
(en)
|
1986-06-26 |
1988-12-13 |
Takeda Chemical Industries, Ltd. |
Chemically modified protein with polyethyleneglycol
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
US5260203A
(en)
|
1986-09-02 |
1993-11-09 |
Enzon, Inc. |
Single polypeptide chain binding molecules
|
WO1988001649A1
(en)
|
1986-09-02 |
1988-03-10 |
Genex Corporation |
Single polypeptide chain binding molecules
|
DE3883899T3
(de)
|
1987-03-18 |
1999-04-22 |
Sb2 Inc |
Geänderte antikörper.
|
EP0623679B1
(de)
|
1987-05-21 |
2003-06-25 |
Micromet AG |
Multifunktionelle Proteine mit vorbestimmter Zielsetzung
|
US4790824A
(en)
|
1987-06-19 |
1988-12-13 |
Bioject, Inc. |
Non-invasive hypodermic injection device
|
US4941880A
(en)
|
1987-06-19 |
1990-07-17 |
Bioject, Inc. |
Pre-filled ampule and non-invasive hypodermic injection device assembly
|
ATE108965T1
(de)
|
1987-12-09 |
1994-08-15 |
Omron Tateisi Electronics Co |
Induktives datenübertragungssystem.
|
KR970008597B1
(ko)
|
1987-12-28 |
1997-05-27 |
닛뽄 세키유가가쿠 가부시키가이샤 |
열가소성수지 조성물의 제조방법
|
US5476996A
(en)
|
1988-06-14 |
1995-12-19 |
Lidak Pharmaceuticals |
Human immune system in non-human animal
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
US5175384A
(en)
|
1988-12-05 |
1992-12-29 |
Genpharm International |
Transgenic mice depleted in mature t-cells and methods for making transgenic mice
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
EP0402226A1
(de)
|
1989-06-06 |
1990-12-12 |
Institut National De La Recherche Agronomique |
Transformationsvektoren für Hefe Yarrowia
|
US5683888A
(en)
|
1989-07-22 |
1997-11-04 |
University Of Wales College Of Medicine |
Modified bioluminescent proteins and their use
|
US5013556A
(en)
|
1989-10-20 |
1991-05-07 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
US5312335A
(en)
|
1989-11-09 |
1994-05-17 |
Bioject Inc. |
Needleless hypodermic injection device
|
US5064413A
(en)
|
1989-11-09 |
1991-11-12 |
Bioject, Inc. |
Needleless hypodermic injection device
|
US5859205A
(en)
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
US5292658A
(en)
|
1989-12-29 |
1994-03-08 |
University Of Georgia Research Foundation, Inc. Boyd Graduate Studies Research Center |
Cloning and expressions of Renilla luciferase
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
SG48759A1
(en)
|
1990-01-12 |
2002-07-23 |
Abgenix Inc |
Generation of xenogenic antibodies
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
US6673986B1
(en)
|
1990-01-12 |
2004-01-06 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
FR2664073A1
(fr)
|
1990-06-29 |
1992-01-03 |
Thomson Csf |
Moyens de marquage d'objets, procede de realisation et dispositif de lecture.
|
US5877397A
(en)
|
1990-08-29 |
1999-03-02 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
KR100272077B1
(ko)
|
1990-08-29 |
2000-11-15 |
젠팜인터내셔날,인코포레이티드 |
이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
WO1992003917A1
(en)
|
1990-08-29 |
1992-03-19 |
Genpharm International |
Homologous recombination in mammalian cells
|
US6300129B1
(en)
|
1990-08-29 |
2001-10-09 |
Genpharm International |
Transgenic non-human animals for producing heterologous antibodies
|
US5874299A
(en)
|
1990-08-29 |
1999-02-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US6255458B1
(en)
|
1990-08-29 |
2001-07-03 |
Genpharm International |
High affinity human antibodies and human antibodies against digoxin
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US5789650A
(en)
|
1990-08-29 |
1998-08-04 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
CA2105984C
(en)
|
1991-03-11 |
2002-11-26 |
Milton J. Cormier |
Cloning and expression of renilla luciferase
|
WO1992022670A1
(en)
|
1991-06-12 |
1992-12-23 |
Genpharm International, Inc. |
Early detection of transgenic embryos
|
AU2235992A
(en)
|
1991-06-14 |
1993-01-12 |
Genpharm International, Inc. |
Transgenic immunodeficient non-human animals
|
JP4124480B2
(ja)
|
1991-06-14 |
2008-07-23 |
ジェネンテック・インコーポレーテッド |
免疫グロブリン変異体
|
AU2515992A
(en)
|
1991-08-20 |
1993-03-16 |
Genpharm International, Inc. |
Gene targeting in animal cells using isogenic dna constructs
|
ES2136092T3
(es)
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
Procedimientos para la produccion de anticuerpos humanizados.
|
EP0746609A4
(de)
|
1991-12-17 |
1997-12-17 |
Genpharm Int |
Heterologe antikörper produzierende transgene nicht-humane tiere
|
US5470582A
(en)
|
1992-02-07 |
1995-11-28 |
Syntex (U.S.A.) Inc. |
Controlled delivery of pharmaceuticals from preformed porous polymeric microparticles
|
EP0648265A4
(de)
|
1992-06-18 |
1996-12-04 |
Genpharm Int |
Methoden zur herstellung von nicht-humanen transgenen tieren die ein artifizielles hefe chromosom enthalten.
|
WO1994002602A1
(en)
|
1992-07-24 |
1994-02-03 |
Cell Genesys, Inc. |
Generation of xenogeneic antibodies
|
US5383851A
(en)
|
1992-07-24 |
1995-01-24 |
Bioject Inc. |
Needleless hypodermic injection device
|
PT672141E
(pt)
|
1992-10-23 |
2003-09-30 |
Immunex Corp |
Metodos de preparacao de proteinas oligomericas soluveis
|
US5981175A
(en)
|
1993-01-07 |
1999-11-09 |
Genpharm Internation, Inc. |
Methods for producing recombinant mammalian cells harboring a yeast artificial chromosome
|
EP0754225A4
(de)
|
1993-04-26 |
2001-01-31 |
Genpharm Int |
Heterologe antikörper produzierende transgene nicht-humane tiere
|
US7045128B2
(en)
|
1993-05-24 |
2006-05-16 |
Immunex Corporation |
Antibodies against flt3-ligand
|
NZ314644A
(en)
|
1993-05-24 |
2000-11-24 |
Immunex Corp |
Use of flt3-ligands as a growth stimulator of stem cells in the transplantation of tissue
|
AU694745B2
(en)
|
1993-09-10 |
1998-07-30 |
Trustees Of Columbia University In The City Of New York, The |
Uses of green fluorescent protein
|
US5625825A
(en)
|
1993-10-21 |
1997-04-29 |
Lsi Logic Corporation |
Random number generating apparatus for an interface unit of a carrier sense with multiple access and collision detect (CSMA/CD) ethernet data network
|
WO1995021191A1
(en)
|
1994-02-04 |
1995-08-10 |
William Ward |
Bioluminescent indicator based upon the expression of a gene for a modified green-fluorescent protein
|
US5643763A
(en)
|
1994-11-04 |
1997-07-01 |
Genpharm International, Inc. |
Method for making recombinant yeast artificial chromosomes by minimizing diploid doubling during mating
|
US6214388B1
(en)
|
1994-11-09 |
2001-04-10 |
The Regents Of The University Of California |
Immunoliposomes that optimize internalization into target cells
|
US5777079A
(en)
|
1994-11-10 |
1998-07-07 |
The Regents Of The University Of California |
Modified green fluorescent proteins
|
KR100654645B1
(ko)
|
1995-04-27 |
2007-04-04 |
아브게닉스, 인크. |
면역화된 제노마우스 유래의 인간 항체
|
CA2219486A1
(en)
|
1995-04-28 |
1996-10-31 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
US5811524A
(en)
|
1995-06-07 |
1998-09-22 |
Idec Pharmaceuticals Corporation |
Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof
|
ATE219517T1
(de)
|
1995-08-18 |
2002-07-15 |
Morphosys Ag |
Protein-/(poly)peptidbibliotheken
|
DK0843961T3
(da)
|
1995-08-29 |
2007-05-21 |
Kirin Brewery |
Kimærisk mus og fremgangsmåde til at producere samme
|
US5874304A
(en)
|
1996-01-18 |
1999-02-23 |
University Of Florida Research Foundation, Inc. |
Humanized green fluorescent protein genes and methods
|
US5804387A
(en)
|
1996-02-01 |
1998-09-08 |
The Board Of Trustees Of The Leland Stanford Junior University |
FACS-optimized mutants of the green fluorescent protein (GFP)
|
US5876995A
(en)
|
1996-02-06 |
1999-03-02 |
Bryan; Bruce |
Bioluminescent novelty items
|
US5925558A
(en)
|
1996-07-16 |
1999-07-20 |
The Regents Of The University Of California |
Assays for protein kinases using fluorescent protein substrates
|
US5976796A
(en)
|
1996-10-04 |
1999-11-02 |
Loma Linda University |
Construction and expression of renilla luciferase and green fluorescent protein fusion genes
|
KR20080059467A
(ko)
|
1996-12-03 |
2008-06-27 |
아브게닉스, 인크. |
복수의 vh 및 vk 부위를 함유하는 사람 면역글로불린유전자좌를 갖는 형질전환된 포유류 및 이로부터 생성된항체
|
EP1015872B1
(de)
|
1996-12-12 |
2005-03-02 |
Prolume, Ltd. |
Vorrichtung und verfahren zum nachweis und identifizieren von infektiösen wirkstoffen
|
EP1724282B1
(de)
|
1997-05-21 |
2013-05-15 |
Merck Patent GmbH |
Verfahren zur Herstellung von nicht-immunogenen Proteinen
|
CA2324648C
(en)
|
1998-03-27 |
2013-02-26 |
Prolume, Ltd. |
Luciferases, fluorescent proteins, nucleic acids encoding the luciferases and fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items
|
BRPI9909860B8
(pt)
|
1998-04-21 |
2021-05-25 |
Amgen Res Munich Gmbh |
polipeptídeo multifuncional de cadeia simples, polinucleotídeo, vetor, célula procariótica, de levedura ou unicelular, composição, usos de polipeptídeo e polinucleotídeo e métodos para preparo do referido polipeptídeo e para identificação de ativadores ou inibidores de ativação ou estimulação das células t
|
DK1100830T3
(da)
|
1998-07-28 |
2004-01-19 |
Micromet Ag |
Heterominiantistoffer
|
US7254167B2
(en)
|
1998-10-30 |
2007-08-07 |
Broadcom Corporation |
Constellation-multiplexed transmitter and receiver
|
CA2342967A1
(en)
|
1998-12-08 |
2000-06-15 |
Biovation Limited |
Modifying protein immunogenicity
|
US6833268B1
(en)
|
1999-06-10 |
2004-12-21 |
Abgenix, Inc. |
Transgenic animals for producing specific isotypes of human antibodies via non-cognate switch regions
|
US7230167B2
(en)
|
2001-08-31 |
2007-06-12 |
Syngenta Participations Ag |
Modified Cry3A toxins and nucleic acid sequences coding therefor
|
JP2005510253A
(ja)
|
2001-11-30 |
2005-04-21 |
アブジェニックス インコーポレイテッド |
ヒトIgλ軽鎖遺伝子を保有するトランスジェニック動物
|
US8486859B2
(en)
|
2002-05-15 |
2013-07-16 |
Bioenergy, Inc. |
Use of ribose to enhance plant growth
|
CA2522586C
(en)
*
|
2003-05-31 |
2017-02-21 |
Micromet Ag |
Pharmaceutical compositions comprising bispecific anti-cd3, anti-cd19 antibody constructs for the treatment of b-cell related disorders
|
US7904068B2
(en)
|
2003-06-06 |
2011-03-08 |
At&T Intellectual Property I, L.P. |
System and method for providing integrated voice and data services utilizing wired cordless access with unlicensed spectrum and wired access with licensed spectrum
|
KR20130065723A
(ko)
|
2003-06-27 |
2013-06-19 |
암젠 프레몬트 인코포레이티드 |
상피 성장 인자 수용체의 결실 돌연변이체 지향 항체 및 그 용도
|
CA2540703C
(en)
|
2003-10-03 |
2014-04-08 |
Board Of Regents, University Of Texas System |
Methods and compositions for mycoplasma pneumoniae exotoxins
|
BRPI0415457A
(pt)
|
2003-10-16 |
2006-12-05 |
Micromet Ag |
constructo de ligação especìfico de cd3 citotoxicamente ativo, seu processo de produção, composição compreendendo o mesmo, seqüência de ácido nucléico, vetor, hospedeiro, seus usos na preparação de uma composição farmacêutica e kit compreendendo os mesmo
|
EP1697520A2
(de)
|
2003-12-22 |
2006-09-06 |
Xencor, Inc. |
Fc-polypeptide mit neuen fc-ligandenbindungsstellen
|
DE602006017460D1
(de)
|
2005-03-14 |
2010-11-25 |
Omron Tateisi Electronics Co |
Programmierbares Steuersystem
|
EA012801B1
(ru)
|
2005-06-14 |
2009-12-30 |
Эмджен Инк. |
Самобуферирующиеся композиции белков
|
US8234145B2
(en)
|
2005-07-12 |
2012-07-31 |
International Business Machines Corporation |
Automatic computation of validation metrics for global logistics processes
|
BRPI0604215A
(pt)
|
2005-08-17 |
2007-04-10 |
Biosigma Sa |
método para projetar oligonucleotìdeos para técnicas de biologia molecular
|
AU2006301492B2
(en)
|
2005-10-11 |
2011-06-09 |
Amgen Research (Munich) Gmbh |
Compositions comprising cross-species-specific antibodies and uses thereof
|
JP2007122396A
(ja)
|
2005-10-27 |
2007-05-17 |
Hitachi Ltd |
ディスクアレイ装置及びその障害対応検証方法
|
TW200745163A
(en)
|
2006-02-17 |
2007-12-16 |
Syntonix Pharmaceuticals Inc |
Peptides that block the binding of IgG to FcRn
|
US7919297B2
(en)
|
2006-02-21 |
2011-04-05 |
Cornell Research Foundation, Inc. |
Mutants of Aspergillus niger PhyA phytase and Aspergillus fumigatus phytase
|
US7574748B2
(en)
|
2006-03-07 |
2009-08-18 |
Nike, Inc. |
Glove with support system
|
US7990860B2
(en)
|
2006-06-16 |
2011-08-02 |
Harris Corporation |
Method and system for rule-based sequencing for QoS
|
US8430938B1
(en)
|
2006-07-13 |
2013-04-30 |
The United States Of America As Represented By The Secretary Of The Navy |
Control algorithm for autothermal reformer
|
GB0614780D0
(en)
|
2006-07-25 |
2006-09-06 |
Ucb Sa |
Biological products
|
KR101146588B1
(ko)
|
2006-08-11 |
2012-05-16 |
삼성전자주식회사 |
Fin 구조체 및 이를 이용한 핀 트랜지스터의 제조방법
|
CN100589507C
(zh)
|
2006-10-30 |
2010-02-10 |
华为技术有限公司 |
一种拨号提示系统及方法
|
US7466008B2
(en)
|
2007-03-13 |
2008-12-16 |
Taiwan Semiconductor Manufacturing Company, Ltd. |
BiCMOS performance enhancement by mechanical uniaxial strain and methods of manufacture
|
AU2008234020B2
(en)
|
2007-04-03 |
2013-02-07 |
Amgen Research (Munich) Gmbh |
Cross-species-specific CD3-epsilon binding domain
|
PL2155783T5
(pl)
*
|
2007-04-03 |
2023-03-13 |
Amgen Research (Munich) Gmbh |
Swoista międzygatunkowo domena wiążąca CD3epsilon
|
US20080260738A1
(en)
|
2007-04-18 |
2008-10-23 |
Moore Margaret D |
Single chain fc, methods of making and methods of treatment
|
CN101802197A
(zh)
*
|
2007-05-14 |
2010-08-11 |
比奥根艾迪克Ma公司 |
单链FC(ScFc)区、包含其的结合多肽及与其相关的方法
|
US8209741B2
(en)
|
2007-09-17 |
2012-06-26 |
Microsoft Corporation |
Human performance in human interactive proofs using partial credit
|
US8464584B2
(en)
|
2007-10-19 |
2013-06-18 |
Food Equipment Technologies Company, Inc. |
Beverage dispenser with level measuring apparatus and display
|
CN101883933B
(zh)
|
2007-11-29 |
2014-04-23 |
舍弗勒技术股份两合公司 |
尤其是用于在驱动机与从动部分之间传递功率的力传递装置
|
US8376279B2
(en)
|
2008-01-23 |
2013-02-19 |
Aurora Flight Sciences Corporation |
Inflatable folding wings for a very high altitude aircraft
|
JP2011516603A
(ja)
|
2008-04-17 |
2011-05-26 |
アブリンクス エン.ヴェー. |
血清タンパク質と結合することが可能なペプチド、並びにこれを含む化合物、構築物及びポリペプチド
|
WO2009132058A2
(en)
|
2008-04-25 |
2009-10-29 |
Zymogenetics, Inc. |
Levels of bcma protein expression on b cells and use in diagnostic methods
|
PT2356153T
(pt)
|
2008-10-01 |
2016-07-15 |
Amgen Res (Munich) Gmbh |
Anticorpo biespecífico, de cadeia única, amepxcd3, específico interespécies
|
EP2352765B1
(de)
|
2008-10-01 |
2018-01-03 |
Amgen Research (Munich) GmbH |
Bispezifischer einzelkettenantikörper mit kreuz-spezies-spezifischer einzeldomäne
|
US20110263484A1
(en)
|
2008-10-13 |
2011-10-27 |
Zymogenetics, Inc. |
Single chain fc type iii interferons and methods of using same
|
BRPI1011478B1
(pt)
|
2009-03-04 |
2018-01-30 |
Nissan Motor Co.,Ltd |
catalisador purificador de gás de exaustão e método para a fabricação do mesmo
|
NZ612647A
(en)
|
2009-03-10 |
2015-03-27 |
Biogen Idec Inc |
Anti-bcma antibodies
|
US8463191B2
(en)
|
2009-04-02 |
2013-06-11 |
Qualcomm Incorporated |
Beamforming options with partial channel knowledge
|
AR076284A1
(es)
*
|
2009-04-29 |
2011-06-01 |
Bayer Schering Pharma Ag |
Inmunoconjugados de antimesotelina y usos de los mismos
|
JP2013509170A
(ja)
|
2009-10-30 |
2013-03-14 |
ノボザイムス バイオファーマ デーコー アクティーゼルスカブ |
アルブミン変異体
|
HUE028629T2
(en)
|
2009-12-23 |
2016-12-28 |
Synimmune Gmbh |
Anti-FLT3 antibodies and ways of their use
|
US20130129723A1
(en)
|
2009-12-29 |
2013-05-23 |
Emergent Product Development Seattle, Llc |
Heterodimer Binding Proteins and Uses Thereof
|
TWI653333B
(zh)
|
2010-04-01 |
2019-03-11 |
安進研究(慕尼黑)有限責任公司 |
跨物種專一性之PSMAxCD3雙專一性單鏈抗體
|
US8691771B2
(en)
|
2010-05-21 |
2014-04-08 |
Merrimack Pharmaceuticals, Inc. |
Bi-specific fusion proteins for tissue repair
|
US20130225496A1
(en)
|
2010-11-01 |
2013-08-29 |
Novozymes Biopharma Dk A/S |
Albumin Variants
|
SG190174A1
(en)
|
2010-11-10 |
2013-07-31 |
Amgen Res Munich Gmbh |
Prevention of adverse effects caused by cd3 specific binding domains
|
EP2640750A1
(de)
|
2010-11-16 |
2013-09-25 |
Boehringer Ingelheim International GmbH |
Mittel und verfahren zur behandlung von mit bcma-expression korrelierenden erkrankungen
|
PT2647707T
(pt)
|
2010-11-30 |
2018-11-15 |
Chugai Pharmaceutical Co Ltd |
Agente terapêutico indutor de toxicidade
|
UA115641C2
(uk)
|
2010-12-20 |
2017-11-27 |
Дженентек, Інк. |
Виділене антитіло, яке зв'язує мезотелін, та імунокон'югат, що його містить
|
WO2012088461A2
(en)
|
2010-12-23 |
2012-06-28 |
Biogen Idec Inc. |
Linker peptides and polypeptides comprising same
|
EP2658739B1
(de)
|
2010-12-30 |
2017-02-22 |
Johnson Controls Metals and Mechanisms GmbH & Co. KG |
Längsverstellvorrichtung eines kraftfahrzeugsitzes mit zwei schienenpaaren
|
RU2650784C2
(ru)
|
2011-05-05 |
2018-04-17 |
Альбумедикс А/С |
Варианты альбумина
|
US20130078250A1
(en)
|
2011-08-23 |
2013-03-28 |
Oliver Ast |
Bispecific t cell activating antigen binding molecules
|
LT2748201T
(lt)
|
2011-08-23 |
2018-02-26 |
Roche Glycart Ag |
Dvigubai specifinė t ląsteles aktyvinantį antigeną surišanti molekulė
|
CL2014001263A1
(es)
|
2011-11-15 |
2014-10-10 |
Boehringer Ingelheim Int |
Molécula de unión biespecífica para bcma y cd3; secuencia de ácido nucleico que la codifica; vector ; célula; composición farmacéutica que comprende a la molécula de unión; uso para tratar enfermedades relacionadas a transtornos de células plasmáticas, trastornos de células b correlacionados con la expresión de bcma y enfermedades autoinmunes.
|
TWI679212B
(zh)
|
2011-11-15 |
2019-12-11 |
美商安進股份有限公司 |
針對bcma之e3以及cd3的結合分子
|
AU2012340174A1
(en)
|
2011-11-16 |
2014-05-29 |
Amgen Inc. |
Methods of treating epidermal growth factor deletion mutant VIII related disorders
|
EP2780364A2
(de)
|
2011-11-18 |
2014-09-24 |
Eleven Biotherapeutics, Inc. |
Proteine mit verbesserter halbwertzeit und anderen eigenschaften
|
SI2794658T1
(sl)
|
2011-12-19 |
2017-05-31 |
Synimmune Gmbh |
Bispecifična molekula protitelesa
|
PE20190658A1
(es)
|
2012-02-24 |
2019-05-08 |
Abbvie Stemcentrx Llc |
Moduladores y metodos de empleo novedosos
|
EP2820047B1
(de)
|
2012-03-01 |
2018-04-25 |
Amgen Research (Munich) GmbH |
Langlebige polypeptidbindungsmoleküle
|
KR20140136934A
(ko)
|
2012-03-16 |
2014-12-01 |
노보자임스 바이오파마 디케이 에이/에스 |
알부민 변이체
|
WO2013185010A1
(en)
|
2012-06-07 |
2013-12-12 |
Duke University |
HUMAN BISPECIFIC EGFRvIII ANTIBODY ENGAGING MOLECULES
|
WO2014004549A2
(en)
*
|
2012-06-27 |
2014-01-03 |
Amgen Inc. |
Anti-mesothelin binding proteins
|
US20140154253A1
(en)
*
|
2012-07-13 |
2014-06-05 |
Zymeworks Inc. |
Bispecific Asymmetric Heterodimers Comprising Anti-CD3 Constructs
|
CA2882753C
(en)
|
2012-08-21 |
2021-08-24 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Mesothelin domain-specific monoclonal antibodies and use thereof
|
JOP20200236A1
(ar)
|
2012-09-21 |
2017-06-16 |
Regeneron Pharma |
الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها
|
BR112015010318A2
(pt)
|
2012-11-08 |
2017-08-22 |
Albumedix As |
Variantes de albumina
|
US9914785B2
(en)
|
2012-11-28 |
2018-03-13 |
Zymeworks Inc. |
Engineered immunoglobulin heavy chain-light chain pairs and uses thereof
|
US9243058B2
(en)
|
2012-12-07 |
2016-01-26 |
Amgen, Inc. |
BCMA antigen binding proteins
|
WO2014100490A1
(en)
|
2012-12-19 |
2014-06-26 |
Adimab, Llc |
Multivalent antibody analogs, and methods of their preparation and use
|
EP2943511B1
(de)
|
2013-01-14 |
2019-08-07 |
Xencor, Inc. |
Neuartige heterodimere proteine
|
JO3519B1
(ar)
|
2013-01-25 |
2020-07-05 |
Amgen Inc |
تركيبات أجسام مضادة لأجل cdh19 و cd3
|
ES2667420T3
(es)
|
2013-02-05 |
2018-05-10 |
Engmab Sàrl |
Anticuerpos biespecíficos contra cd3epsilon y bcma
|
GB201302447D0
(en)
|
2013-02-12 |
2013-03-27 |
Oxford Biotherapeutics Ltd |
Therapeutic and diagnostic target
|
DK2961771T3
(da)
|
2013-02-26 |
2020-03-02 |
Roche Glycart Ag |
Bispecifikke, T-celle-aktiverende, antigenbindende molekyler, der er specifikke for CD3 og CEA
|
KR20150143458A
(ko)
|
2013-03-06 |
2015-12-23 |
메리맥 파마슈티컬즈, 인크. |
항-C-MET 탠덤 Fc 이중특이적 항체
|
US9580486B2
(en)
|
2013-03-14 |
2017-02-28 |
Amgen Inc. |
Interleukin-2 muteins for the expansion of T-regulatory cells
|
SI2970449T1
(sl)
|
2013-03-15 |
2019-11-29 |
Amgen Res Munich Gmbh |
Enoverižne vezavne molekule, ki vsebujejo N-terminalni ABP
|
US20140308285A1
(en)
*
|
2013-03-15 |
2014-10-16 |
Amgen Inc. |
Heterodimeric bispecific antibodies
|
US20140302037A1
(en)
|
2013-03-15 |
2014-10-09 |
Amgen Inc. |
BISPECIFIC-Fc MOLECULES
|
AR095374A1
(es)
|
2013-03-15 |
2015-10-14 |
Amgen Res (Munich) Gmbh |
Moléculas de unión para bcma y cd3
|
EP2970484B2
(de)
|
2013-03-15 |
2022-09-21 |
Amgen Inc. |
Heterodimere bispezifische antikörper
|
JP6071725B2
(ja)
|
2013-04-23 |
2017-02-01 |
カルソニックカンセイ株式会社 |
電気自動車の駆動力制御装置
|
TR201904121T4
(tr)
|
2013-07-09 |
2019-04-22 |
The Government Of The United States As Represented By The Secretary Of The Dept Of Health And Human |
İnsan bispesifik egfrviii antikoru birleştirme molekülleri.
|
WO2015018527A1
(en)
|
2013-08-07 |
2015-02-12 |
Affimed Therapeutics Ag |
ANTIBODY BINDING SITES SPECIFIC FOR EGFRvIII
|
EP2840091A1
(de)
|
2013-08-23 |
2015-02-25 |
MacroGenics, Inc. |
Bispezifische Diabodies, die gpA33 und CD3 binden können und Anwendungen dieser
|
AR097648A1
(es)
|
2013-09-13 |
2016-04-06 |
Amgen Inc |
Combinación de factores epigenéticos y compuestos biespecíficos que tienen como diana cd33 y cd3 en el tratamiento de leucemia mieloide
|
EP3049440B1
(de)
|
2013-09-25 |
2020-03-25 |
Amgen Inc. |
V-c-fc-v-c-antikörper
|
GB2519786A
(en)
|
2013-10-30 |
2015-05-06 |
Sergej Michailovic Kiprijanov |
Multivalent antigen-binding protein molecules
|
PE20210107A1
(es)
|
2013-12-17 |
2021-01-19 |
Genentech Inc |
Anticuerpos anti-cd3 y metodos de uso
|
RU2698969C2
(ru)
|
2014-01-15 |
2019-09-02 |
Ф.Хоффманн-Ля Рош Аг |
Варианты fc-области с улучшенной способностью связываться с белком а
|
JP6775422B2
(ja)
|
2014-03-28 |
2020-10-28 |
ゼンコー・インコーポレイテッドXencor、 Inc. |
Cd38及びcd3に結合する二重特異性抗体
|
US9300829B2
(en)
|
2014-04-04 |
2016-03-29 |
Canon Kabushiki Kaisha |
Image reading apparatus and correction method thereof
|
EP3107938B1
(de)
|
2014-05-28 |
2022-05-04 |
Zymeworks Inc. |
Modifizierte antigenbindende polypeptidkonstrukte sowie verwendungen davon
|
EP3174901B1
(de)
*
|
2014-07-31 |
2019-06-26 |
Amgen Research (Munich) GmbH |
Optimierte artenübergreifende spezifische bispezifische einkettige antikörperkonstrukte
|
UY36245A
(es)
*
|
2014-07-31 |
2016-01-29 |
Amgen Res Munich Gmbh |
Constructos de anticuerpos para cdh19 y cd3
|
AU2015295242B2
(en)
*
|
2014-07-31 |
2020-10-22 |
Amgen Research (Munich) Gmbh |
Bispecific single chain antibody construct with enhanced tissue distribution
|
MA50584A
(fr)
|
2014-08-04 |
2020-09-16 |
Hoffmann La Roche |
Molécules bispécifiques de liaison à l'antigène activant des lymphocytes t
|
US10105142B2
(en)
|
2014-09-18 |
2018-10-23 |
Ethicon Llc |
Surgical stapler with plurality of cutting elements
|
AU2015323313B2
(en)
*
|
2014-09-25 |
2021-04-01 |
Amgen Inc. |
Protease-activatable bispecific proteins
|
MA40894A
(fr)
|
2014-11-04 |
2017-09-12 |
Glenmark Pharmaceuticals Sa |
Immunoglobulines hétéro-dimères reciblant des lymphocytes t cd3/cd38 et leurs procédés de production
|
US10259887B2
(en)
*
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
MA41019A
(fr)
|
2014-11-26 |
2021-05-05 |
Xencor Inc |
Anticorps hétérodimériques se liant aux antigènes cd3 et cd38
|
EP3223845B1
(de)
*
|
2014-11-26 |
2021-05-19 |
Xencor, Inc. |
Cheterodimere antikörper zur bindung von cd3 und cd20
|
CN104829728B
(zh)
|
2015-01-21 |
2019-03-12 |
武汉友芝友生物制药有限公司 |
一种双特异性抗体her2xcd3的构建及应用
|
CN104829726B
(zh)
|
2015-01-21 |
2019-03-05 |
武汉友芝友生物制药有限公司 |
一种双特异性抗体cd19xcd3的构建及应用
|
EP3247725B1
(de)
|
2015-01-23 |
2020-07-01 |
Sanofi |
Anti-cd3-antikörper, anti-cd123-antikörper und bispezifische, spezifisch an cd3 und/oder cd123 bindende antikörper
|
EP3253414A4
(de)
*
|
2015-02-05 |
2018-07-11 |
The University Of Queensland |
Zielkonstrukte zur lieferung von nutzlasten
|
SG10201909308XA
(en)
|
2015-04-17 |
2019-11-28 |
Amgen Res Munich Gmbh |
Bispecific antibody constructs for cdh3 and cd3
|
TWI717375B
(zh)
|
2015-07-31 |
2021-02-01 |
德商安美基研究(慕尼黑)公司 |
Cd70及cd3抗體構築體
|
TWI796283B
(zh)
*
|
2015-07-31 |
2023-03-21 |
德商安美基研究(慕尼黑)公司 |
Msln及cd3抗體構築體
|
TWI744242B
(zh)
|
2015-07-31 |
2021-11-01 |
德商安美基研究(慕尼黑)公司 |
Egfrviii及cd3抗體構築體
|
TWI829617B
(zh)
|
2015-07-31 |
2024-01-21 |
德商安美基研究(慕尼黑)公司 |
Flt3及cd3抗體構築體
|
TW202346349A
(zh)
|
2015-07-31 |
2023-12-01 |
德商安美基研究(慕尼黑)公司 |
Dll3及cd3抗體構築體
|
CA2995754A1
(en)
|
2015-08-17 |
2017-02-23 |
Janssen Pharmaceutica Nv |
Anti-bcma antibodies, bispecific antigen binding molecules that bind bcma and cd3, and uses thereof
|
BR112018008908A2
(pt)
|
2015-11-02 |
2018-11-27 |
Janssen Pharmaceutica Nv |
anticorpos anti-il1rap, moléculas de ligação ao antígeno biespecíficas que se ligam il1rap e cd3, e seus usos
|
US9552854B1
(en)
|
2015-11-10 |
2017-01-24 |
Intel Corporation |
Register files including distributed capacitor circuit blocks
|
JOP20170017B1
(ar)
*
|
2016-01-25 |
2021-08-17 |
Amgen Res Munich Gmbh |
تركيب صيدلي يتضمن تركيبات جسم مضاد ثنائي الاختصاص
|
EA039859B1
(ru)
|
2016-02-03 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкты антител, связывающие egfrviii и cd3
|
UA126656C2
(uk)
|
2016-02-03 |
2023-01-11 |
Емджен Рісерч (Мюнік) Гмбх |
Біспецифічна конструкція антитіла до psma і cd3, яке залучають t-клітини
|
MA43955B1
(fr)
|
2016-02-03 |
2022-02-28 |
Amgen Inc |
Anticorps anti-bcma et anti-cd3 bispécifiques de format bite
|
US9567399B1
(en)
*
|
2016-06-20 |
2017-02-14 |
Kymab Limited |
Antibodies and immunocytokines
|
TWI790206B
(zh)
|
2016-07-18 |
2023-01-21 |
法商賽諾菲公司 |
特異性結合至cd3和cd123的雙特異性抗體樣結合蛋白
|
TWI781108B
(zh)
|
2016-07-20 |
2022-10-21 |
比利時商健生藥品公司 |
抗gprc5d抗體、結合gprc5d與cd3之雙特異性抗原結合分子及其用途
|
EA201990781A9
(ru)
|
2016-09-23 |
2019-11-27 |
|
Анти-steap2 антитела, конъюгаты антитело-лекарственное средство и биспецифические антигенсвязывающие молекулы, которые связывают steap2 и cd3, и их применение
|
US10941208B2
(en)
|
2016-09-23 |
2021-03-09 |
Regeneron Pharmaceuticals, Inc. |
Anti-MUC16 antibodies
|
JP7267914B2
(ja)
|
2016-11-02 |
2023-05-02 |
エンクマフ エスアーエールエル |
Bcma及びcd3に対する二重特異性抗体、及び多発性骨髄腫を治療するために併用して使用される免疫療法薬
|
AU2018261951A1
(en)
*
|
2017-05-05 |
2019-10-31 |
Amgen Inc. |
Pharmaceutical composition comprising bispecific antibody constructs for improved storage and administration
|
US11284893B2
(en)
|
2019-04-02 |
2022-03-29 |
Covidien Lp |
Stapling device with articulating tool assembly
|