SE9300977L - - Google Patents

Info

Publication number
SE9300977L
SE9300977L SE9300977A SE9300977A SE9300977L SE 9300977 L SE9300977 L SE 9300977L SE 9300977 A SE9300977 A SE 9300977A SE 9300977 A SE9300977 A SE 9300977A SE 9300977 L SE9300977 L SE 9300977L
Authority
SE
Sweden
Application number
SE9300977A
Other versions
SE9300977D0 (sv
SE512485C2 (sv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication of SE9300977L publication Critical patent/SE9300977L/xx
Application filed filed Critical
Publication of SE9300977D0 publication Critical patent/SE9300977D0/xx
Publication of SE512485C2 publication Critical patent/SE512485C2/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SE9300977A 1987-02-25 1993-03-24 Förfarande för framställning av mellanprodukter avsedda för framställning av antihyperkolesterolemiska medel SE512485C2 (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1855887A 1987-02-25 1987-02-25
US07/151,512 US4898949A (en) 1987-02-25 1988-02-18 Intermediates for the preparation of antihypercholesterolemic tetrazole compounds

Publications (3)

Publication Number Publication Date
SE9300977L true SE9300977L (pl)
SE9300977D0 SE9300977D0 (sv) 1993-03-24
SE512485C2 SE512485C2 (sv) 2000-03-20

Family

ID=26691250

Family Applications (3)

Application Number Title Priority Date Filing Date
SE8800637A SE504553C2 (sv) 1987-02-25 1988-02-24 Mellanprodukter och förfaranden för framställning av antihyperkolesterolemiska tetrazolföreningar
SE9300976A SE503201C2 (sv) 1987-02-25 1993-03-24 Tetrazol mellanprodukter för användning för framställning av nya inhibitorer för enzymet HMG-CoA-reduktas
SE9300977A SE512485C2 (sv) 1987-02-25 1993-03-24 Förfarande för framställning av mellanprodukter avsedda för framställning av antihyperkolesterolemiska medel

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SE8800637A SE504553C2 (sv) 1987-02-25 1988-02-24 Mellanprodukter och förfaranden för framställning av antihyperkolesterolemiska tetrazolföreningar
SE9300976A SE503201C2 (sv) 1987-02-25 1993-03-24 Tetrazol mellanprodukter för användning för framställning av nya inhibitorer för enzymet HMG-CoA-reduktas

Country Status (27)

Country Link
US (1) US4898949A (pl)
JP (1) JP2603284B2 (pl)
KR (1) KR960007167B1 (pl)
CN (1) CN1030077C (pl)
AT (1) AT395588B (pl)
AU (1) AU610562B2 (pl)
BE (1) BE1002115A3 (pl)
CA (1) CA1328269C (pl)
CH (1) CH678182A5 (pl)
DE (1) DE3805789C2 (pl)
DK (2) DK97388A (pl)
ES (1) ES2009547A6 (pl)
FI (1) FI96600C (pl)
FR (1) FR2611201B1 (pl)
GB (1) GB2202845B (pl)
GR (1) GR1000473B (pl)
HU (3) HU201532B (pl)
IE (1) IE61608B1 (pl)
IT (1) IT1216752B (pl)
LU (1) LU87143A1 (pl)
MY (1) MY102290A (pl)
NL (1) NL8800468A (pl)
NO (1) NO178432C (pl)
NZ (1) NZ223621A (pl)
PT (1) PT86821B (pl)
SE (3) SE504553C2 (pl)
YU (1) YU46781B (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4870187A (en) * 1988-08-23 1989-09-26 Bristol-Myers Company Antihypercholesterolemic tetrazol-1-yl compounds
FI94339C (fi) 1989-07-21 1995-08-25 Warner Lambert Co Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
US5260325A (en) * 1991-08-19 1993-11-09 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking tertiary amides
CA2137049A1 (en) * 1993-12-15 1995-06-16 John K. Thottathil Amino acid salts of and methods for preparing antihypercholesterolemic tetrazole compounds
NZ504346A (en) * 1997-12-19 2001-11-30 Warner Lambert Exp Ltd Process for the synthesis of 1,3-diols characterised by either reconcentration step with either trialkylborane or dialkylalkoxyborane or a mixture of both trialkylborane and dialkylalkoxyborane

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4160100A (en) * 1973-03-23 1979-07-03 American Home Products Corporation Oxamic acid derivatives
US4013647A (en) * 1976-03-23 1977-03-22 American Home Products Corporation Morpholine containing tetrazole-5-carboxamide derivatives
JPS53147073A (en) * 1977-05-24 1978-12-21 Sankyo Co Ltd Mevalonolactone derivatives
US4567289A (en) * 1979-08-17 1986-01-28 Merck & Co., Inc. Substituted pyranone inhibitors of cholesterol synthesis
US4375475A (en) * 1979-08-17 1983-03-01 Merck & Co., Inc. Substituted pyranone inhibitors of cholesterol synthesis
NZ194557A (en) * 1979-08-17 1984-09-28 Merck & Co Inc Substituted pyranone derivatives;dihydroxy acids therefrom;pharmaceutical compositions
EP0068038B1 (en) * 1981-06-29 1985-09-25 Merck & Co. Inc. (+)-(4r,6s)-(e)-6-(2-(4'-fluoro-3,3',5-trimethyl-(1,1'-biphenyl)-2-yl)ethenyl)-3,4,5,6-tetrahydro-4-hydroxy-2h-pyran-2-one, a process for preparing and a pharmaceutical composition containing the same
WO1984002131A1 (en) * 1982-11-22 1984-06-07 Sandoz Ag Analogs of mevalolactone and derivatives thereof, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals
US4739073A (en) * 1983-11-04 1988-04-19 Sandoz Pharmaceuticals Corp. Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof
ES8609193A1 (es) * 1983-01-24 1986-07-16 Sandoz Ag Procedimiento para preparar analogos de mevalonolactona y derivados de los mismos
US5105017A (en) * 1983-07-18 1992-04-14 Eli Lilly And Company Leukotriene antagonist intermediates
CA1327360C (en) * 1983-11-14 1994-03-01 William F. Hoffman Oxo-analogs of mevinolin-like antihypercholesterolemic agents
US4613610A (en) * 1984-06-22 1986-09-23 Sandoz Pharmaceuticals Corp. Cholesterol biosynthesis inhibiting pyrazole analogs of mevalonolactone and its derivatives
KR890001651B1 (ko) * 1984-06-22 1989-05-12 산도즈 파마슈티칼스 코포레이션 메발로노락톤의 피라졸 동족체 및 이의 유도체의 제조방법
US4668794A (en) * 1985-05-22 1987-05-26 Sandoz Pharm. Corp. Intermediate imidazole acrolein analogs
US4621099A (en) * 1985-09-23 1986-11-04 Usv Pharmaceutical Corporation Polyene compounds useful in the treatment of allergic responses
US4681893A (en) * 1986-05-30 1987-07-21 Warner-Lambert Company Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis
US4678806A (en) * 1986-09-02 1987-07-07 Merck & Co., Inc. Prodrugs of antihypercholesterolemic compounds
AU601264B2 (en) * 1987-02-25 1990-09-06 Bristol-Myers Squibb Company Antihypercholesterolemic tetrazole compounds

Also Published As

Publication number Publication date
CA1328269C (en) 1994-04-05
AU1213288A (en) 1988-09-01
ES2009547A6 (es) 1989-10-01
SE8800637D0 (sv) 1988-02-24
NO178432B (no) 1995-12-18
FI880868A0 (fi) 1988-02-24
SE9300977D0 (sv) 1993-03-24
YU36488A (en) 1990-02-28
SE512485C2 (sv) 2000-03-20
IE880502L (en) 1988-08-18
IE61608B1 (en) 1994-11-16
FI96600B (fi) 1996-04-15
CH678182A5 (pl) 1991-08-15
DK97388A (da) 1988-08-26
AT395588B (de) 1993-01-25
CN1070642A (zh) 1993-04-07
HUT47258A (en) 1989-02-28
MY102290A (en) 1992-05-15
AU610562B2 (en) 1991-05-23
DK97388D0 (da) 1988-02-24
YU46781B (sh) 1994-05-10
DK113897A (da) 1997-10-06
IT8819526A0 (it) 1988-02-24
GB2202845B (en) 1991-05-22
NL8800468A (nl) 1988-09-16
HU895124D0 (pl) 1990-01-28
FI880868A (fi) 1988-08-26
GR1000473B (el) 1992-07-30
SE504553C2 (sv) 1997-03-03
US4898949A (en) 1990-02-06
LU87143A1 (fr) 1988-09-20
GB8804281D0 (en) 1988-03-23
NZ223621A (en) 1991-06-25
NO880802L (no) 1988-08-26
GB2202845A (en) 1988-10-05
FR2611201B1 (fr) 1991-01-11
BE1002115A3 (fr) 1990-07-10
DE3805789C2 (de) 2001-05-31
SE9300976D0 (sv) 1993-03-24
HU201532B (en) 1990-11-28
FI96600C (fi) 1996-07-25
HU201534B (en) 1990-11-28
JP2603284B2 (ja) 1997-04-23
PT86821B (pt) 1992-05-29
DE3805789A1 (de) 1988-09-15
PT86821A (pt) 1988-03-01
KR960007167B1 (ko) 1996-05-29
SE503201C2 (sv) 1996-04-15
HU201533B (en) 1990-11-28
NO880802D0 (no) 1988-02-24
ATA46088A (de) 1992-06-15
JPS63290872A (ja) 1988-11-28
FR2611201A1 (fr) 1988-08-26
SE9300976L (pl) 1993-03-24
GR880100100A (en) 1988-12-16
IT1216752B (it) 1990-03-08
NO178432C (no) 1996-03-27
SE8800637L (sv) 1988-08-26
CN1030077C (zh) 1995-10-18
KR880009946A (ko) 1988-10-06

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Legal Events

Date Code Title Description
NUG Patent has lapsed