SE8403375L - Ny plasminogenaktivator, framstellningsprocess for denna samt ett trombolytiskt medel innehallande densamma - Google Patents

Ny plasminogenaktivator, framstellningsprocess for denna samt ett trombolytiskt medel innehallande densamma

Info

Publication number
SE8403375L
SE8403375L SE8403375A SE8403375A SE8403375L SE 8403375 L SE8403375 L SE 8403375L SE 8403375 A SE8403375 A SE 8403375A SE 8403375 A SE8403375 A SE 8403375A SE 8403375 L SE8403375 L SE 8403375L
Authority
SE
Sweden
Prior art keywords
column
plasminogen activator
manufacturing process
agent containing
thrombolytic agent
Prior art date
Application number
SE8403375A
Other languages
Unknown language ( )
English (en)
Swedish (sv)
Other versions
SE8403375D0 (sv
Inventor
Seishi Takahashi
Kazushi Morimoto
Yoshikazu Fujisawa
Fumiaki Ikeda
Original Assignee
Mitsui Toatsu Chemicals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP57189065A external-priority patent/JPH0637398B2/ja
Priority claimed from JP57189067A external-priority patent/JPS5980613A/ja
Application filed by Mitsui Toatsu Chemicals filed Critical Mitsui Toatsu Chemicals
Publication of SE8403375L publication Critical patent/SE8403375L/
Publication of SE8403375D0 publication Critical patent/SE8403375D0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SE8403375A 1982-10-29 1984-06-25 Ny plasminogenaktivator, framstellningsprocess for denna samt ett trombolytiskt medel innehallande densamma SE8403375D0 (sv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP57189065A JPH0637398B2 (ja) 1982-10-29 1982-10-29 血栓溶解剤
JP57189067A JPS5980613A (ja) 1982-10-29 1982-10-29 新規なプラスミノ−ゲン・アクチベ−タ及びその製造方法
PCT/JP1983/000386 WO1984001714A1 (en) 1982-10-29 1983-10-27 Novel plasminogen activator, process for its preparation, and thrombolytic drug containing the same

Publications (2)

Publication Number Publication Date
SE8403375L true SE8403375L (sv) 1984-06-25
SE8403375D0 SE8403375D0 (sv) 1984-06-25

Family

ID=26505289

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8403375A SE8403375D0 (sv) 1982-10-29 1984-06-25 Ny plasminogenaktivator, framstellningsprocess for denna samt ett trombolytiskt medel innehallande densamma

Country Status (12)

Country Link
EP (1) EP0124613B1 (fi)
CA (1) CA1221029A (fi)
CH (1) CH660742A5 (fi)
DE (1) DE3390272C2 (fi)
DK (1) DK169686B1 (fi)
FI (1) FI80597C (fi)
GB (1) GB2138824B (fi)
IT (1) IT1169910B (fi)
NL (1) NL191755C (fi)
NO (1) NO166314C (fi)
SE (1) SE8403375D0 (fi)
WO (1) WO1984001714A1 (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3582338D1 (de) * 1984-01-30 1991-05-08 Asahi Chemical Ind Verfahren zur herstellung eines doppelkettigen plasminogenaktivators.
US4929444A (en) * 1985-05-28 1990-05-29 Burroughs Wellcome Co. Low pH pharmaceutical formulation containing t-PA
IL78937A (en) * 1985-05-28 1990-11-29 Wellcome Found Pharmaceutical compositions containing tissue-plasminogen activator
EP0275282A1 (en) * 1986-07-16 1988-07-27 Celltech Limited Process for purifying a plasminogen activator
JPS6379591A (ja) * 1986-09-22 1988-04-09 Mitsui Toatsu Chem Inc ｔＰＡの精製方法
AU1668988A (en) * 1987-06-03 1988-12-08 Smithkline Beckman Corporation Purification of tpa
DE3726019A1 (de) * 1987-08-05 1989-02-16 Boehringer Mannheim Gmbh Verfahren zur abtrennung und reinigung von t-pa

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8003402A (nl) * 1980-06-11 1982-01-04 Leuven Res & Dev Vzw Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking.
IL68561A (en) * 1982-05-05 1991-01-31 Genentech Inc Preparation of polypeptide with human tissue plasminogen activator function,processes for making it,and dna and transformed cell intermediates thereof
JPS5913732A (ja) * 1982-07-16 1984-01-24 Mitsui Toatsu Chem Inc 血栓溶解剤
IE81073B1 (en) * 1986-03-18 2000-01-12 Genentech Inc Modified human tissue-type plasminogen activator and its preparation

Also Published As

Publication number Publication date
NO166314B (no) 1991-03-25
GB2138824B (en) 1986-12-31
DK307384A (da) 1984-06-22
EP0124613A1 (en) 1984-11-14
EP0124613B1 (en) 1992-12-30
EP0124613A4 (en) 1986-07-29
NL8320346A (nl) 1984-09-03
DK169686B1 (da) 1995-01-09
IT1169910B (it) 1987-06-03
CH660742A5 (de) 1987-06-15
DK307384D0 (da) 1984-06-22
NO166314C (no) 1991-07-03
NL191755C (nl) 1996-07-02
GB2138824A (en) 1984-10-31
FI842627A0 (fi) 1984-06-29
CA1221029A (en) 1987-04-28
FI80597C (fi) 1990-07-10
DE3390272C2 (de) 1987-09-17
IT8323533A0 (it) 1983-10-28
NO842468L (no) 1984-06-19
DE3390272T1 (de) 1984-11-29
FI80597B (fi) 1990-03-30
WO1984001714A1 (en) 1984-05-10
NL191755B (nl) 1996-03-01
GB8414992D0 (en) 1984-07-18
FI842627A (fi) 1984-06-29
SE8403375D0 (sv) 1984-06-25

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