DE3582338D1 - Verfahren zur herstellung eines doppelkettigen plasminogenaktivators. - Google Patents

Verfahren zur herstellung eines doppelkettigen plasminogenaktivators.

Info

Publication number
DE3582338D1
DE3582338D1 DE8585100804T DE3582338T DE3582338D1 DE 3582338 D1 DE3582338 D1 DE 3582338D1 DE 8585100804 T DE8585100804 T DE 8585100804T DE 3582338 T DE3582338 T DE 3582338T DE 3582338 D1 DE3582338 D1 DE 3582338D1
Authority
DE
Germany
Prior art keywords
producing
plasminogen activator
double chain
chain plasminogen
double
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585100804T
Other languages
English (en)
Inventor
Toshihito Mori
Hideo Yoshizaki
Akio Hasegawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Corp
Kowa Co Ltd
Asahi Chemical Industry Co Ltd
Original Assignee
Kowa Co Ltd
Asahi Chemical Industry Co Ltd
Asahi Kasei Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP59013456A external-priority patent/JPS60158117A/ja
Priority claimed from JP59013455A external-priority patent/JPS60158116A/ja
Application filed by Kowa Co Ltd, Asahi Chemical Industry Co Ltd, Asahi Kasei Kogyo KK filed Critical Kowa Co Ltd
Application granted granted Critical
Publication of DE3582338D1 publication Critical patent/DE3582338D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
DE8585100804T 1984-01-30 1985-01-26 Verfahren zur herstellung eines doppelkettigen plasminogenaktivators. Expired - Lifetime DE3582338D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59013456A JPS60158117A (ja) 1984-01-30 1984-01-30 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤
JP59013455A JPS60158116A (ja) 1984-01-30 1984-01-30 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤

Publications (1)

Publication Number Publication Date
DE3582338D1 true DE3582338D1 (de) 1991-05-08

Family

ID=26349257

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585100804T Expired - Lifetime DE3582338D1 (de) 1984-01-30 1985-01-26 Verfahren zur herstellung eines doppelkettigen plasminogenaktivators.

Country Status (3)

Country Link
EP (1) EP0151996B1 (de)
DE (1) DE3582338D1 (de)
ES (2) ES8605583A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61176532A (ja) * 1985-01-30 1986-08-08 Green Cross Corp:The プラスミノ−ゲンアクチベ−タ−前駆体の安定化方法
CA1336585C (en) * 1985-04-16 1995-08-08 Kazuo Morimoto Method of stabilizing urokinase precursor and dry preparation containing said precursor
JPS624233A (ja) * 1985-07-01 1987-01-10 Toyobo Co Ltd 組織性プラスミノ−ゲン活性化因子の製造法
EP0391080A3 (de) * 1989-03-07 1990-11-07 Roche Diagnostics GmbH Verfahren zur Herstellung von zweikettigem t-PA
DE69317264T2 (de) * 1992-11-20 1998-08-27 Seiko Epson Corp Mikroroboter und aufbewahrungsbehälter dafür

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4381346A (en) * 1979-11-13 1983-04-26 Huasin Syed S Isolation of plasminogen activators useful as therapeutic and diagnostic agents
NL8003402A (nl) * 1980-06-11 1982-01-04 Leuven Res & Dev Vzw Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking.
ZA831399B (en) * 1982-03-05 1984-02-29 Health Lab Service Board New fibrinolytic enzymes and methods for their production and pharmaceutical compositions containing them
JPS5913732A (ja) * 1982-07-16 1984-01-24 Mitsui Toatsu Chem Inc 血栓溶解剤
JPS5951220A (ja) * 1982-08-02 1984-03-24 Asahi Chem Ind Co Ltd 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤
NL191755C (nl) * 1982-10-29 1996-07-02 Mitsui Toatsu Chemicals Plasminogeenactivator en trombolytisch middel.

Also Published As

Publication number Publication date
ES8701840A1 (es) 1986-12-01
ES548974A0 (es) 1986-12-01
EP0151996A2 (de) 1985-08-21
ES8605583A1 (es) 1986-03-16
ES539925A0 (es) 1986-03-16
EP0151996A3 (en) 1986-10-01
EP0151996B1 (de) 1991-04-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee