DE3582338D1 - Verfahren zur herstellung eines doppelkettigen plasminogenaktivators. - Google Patents
Verfahren zur herstellung eines doppelkettigen plasminogenaktivators.Info
- Publication number
- DE3582338D1 DE3582338D1 DE8585100804T DE3582338T DE3582338D1 DE 3582338 D1 DE3582338 D1 DE 3582338D1 DE 8585100804 T DE8585100804 T DE 8585100804T DE 3582338 T DE3582338 T DE 3582338T DE 3582338 D1 DE3582338 D1 DE 3582338D1
- Authority
- DE
- Germany
- Prior art keywords
- producing
- plasminogen activator
- double chain
- chain plasminogen
- double
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59013455A JPS60158116A (ja) | 1984-01-30 | 1984-01-30 | 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤 |
JP59013456A JPS60158117A (ja) | 1984-01-30 | 1984-01-30 | 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3582338D1 true DE3582338D1 (de) | 1991-05-08 |
Family
ID=26349257
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8585100804T Expired - Lifetime DE3582338D1 (de) | 1984-01-30 | 1985-01-26 | Verfahren zur herstellung eines doppelkettigen plasminogenaktivators. |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0151996B1 (de) |
DE (1) | DE3582338D1 (de) |
ES (2) | ES8605583A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61176532A (ja) * | 1985-01-30 | 1986-08-08 | Green Cross Corp:The | プラスミノ−ゲンアクチベ−タ−前駆体の安定化方法 |
KR940003056B1 (ko) * | 1985-04-16 | 1994-04-13 | 가부시끼가이샤 미도리 쥬우지 | 우로키나제 전구체를 안정화시키는 방법 |
JPS624233A (ja) * | 1985-07-01 | 1987-01-10 | Toyobo Co Ltd | 組織性プラスミノ−ゲン活性化因子の製造法 |
CA2011548A1 (en) * | 1989-03-07 | 1990-09-07 | Hubertus Stockinger | Process for the production of two-chain t-pa |
DE69317264T2 (de) * | 1992-11-20 | 1998-08-27 | Seiko Epson Corp | Mikroroboter und aufbewahrungsbehälter dafür |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4381346A (en) * | 1979-11-13 | 1983-04-26 | Huasin Syed S | Isolation of plasminogen activators useful as therapeutic and diagnostic agents |
NL8003402A (nl) * | 1980-06-11 | 1982-01-04 | Leuven Res & Dev Vzw | Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking. |
ZA831399B (en) * | 1982-03-05 | 1984-02-29 | Health Lab Service Board | New fibrinolytic enzymes and methods for their production and pharmaceutical compositions containing them |
JPS5913732A (ja) * | 1982-07-16 | 1984-01-24 | Mitsui Toatsu Chem Inc | 血栓溶解剤 |
JPS5951220A (ja) * | 1982-08-02 | 1984-03-24 | Asahi Chem Ind Co Ltd | 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤 |
EP0124613B1 (de) * | 1982-10-29 | 1992-12-30 | MITSUI TOATSU CHEMICALS, Inc. | Neuer plasminogen-aktivator aus menschlichen nieren, dessen herstellungsverfahren und thrombolytisches arzneimittel, das diesen enthält |
-
1985
- 1985-01-26 EP EP85100804A patent/EP0151996B1/de not_active Expired - Lifetime
- 1985-01-26 DE DE8585100804T patent/DE3582338D1/de not_active Expired - Lifetime
- 1985-01-29 ES ES539925A patent/ES8605583A1/es not_active Expired
- 1985-11-16 ES ES548974A patent/ES8701840A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES539925A0 (es) | 1986-03-16 |
EP0151996A2 (de) | 1985-08-21 |
EP0151996A3 (en) | 1986-10-01 |
ES8701840A1 (es) | 1986-12-01 |
ES8605583A1 (es) | 1986-03-16 |
EP0151996B1 (de) | 1991-04-03 |
ES548974A0 (es) | 1986-12-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |