SE8403375L - Ny plasminogenaktivator, framstellningsprocess for denna samt ett trombolytiskt medel innehallande densamma - Google Patents
Ny plasminogenaktivator, framstellningsprocess for denna samt ett trombolytiskt medel innehallande densammaInfo
- Publication number
- SE8403375L SE8403375L SE8403375A SE8403375A SE8403375L SE 8403375 L SE8403375 L SE 8403375L SE 8403375 A SE8403375 A SE 8403375A SE 8403375 A SE8403375 A SE 8403375A SE 8403375 L SE8403375 L SE 8403375L
- Authority
- SE
- Sweden
- Prior art keywords
- column
- plasminogen activator
- manufacturing process
- agent containing
- thrombolytic agent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP57189067A JPS5980613A (ja) | 1982-10-29 | 1982-10-29 | 新規なプラスミノ−ゲン・アクチベ−タ及びその製造方法 |
JP57189065A JPH0637398B2 (ja) | 1982-10-29 | 1982-10-29 | 血栓溶解剤 |
PCT/JP1983/000386 WO1984001714A1 (en) | 1982-10-29 | 1983-10-27 | Novel plasminogen activator, process for its preparation, and thrombolytic drug containing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
SE8403375L true SE8403375L (sv) | 1984-06-25 |
SE8403375D0 SE8403375D0 (sv) | 1984-06-25 |
Family
ID=26505289
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8403375A SE8403375D0 (sv) | 1982-10-29 | 1984-06-25 | Ny plasminogenaktivator, framstellningsprocess for denna samt ett trombolytiskt medel innehallande densamma |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0124613B1 (sv) |
CA (1) | CA1221029A (sv) |
CH (1) | CH660742A5 (sv) |
DE (1) | DE3390272C2 (sv) |
DK (1) | DK169686B1 (sv) |
FI (1) | FI80597C (sv) |
GB (1) | GB2138824B (sv) |
IT (1) | IT1169910B (sv) |
NL (1) | NL191755C (sv) |
NO (1) | NO166314C (sv) |
SE (1) | SE8403375D0 (sv) |
WO (1) | WO1984001714A1 (sv) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0151996B1 (en) * | 1984-01-30 | 1991-04-03 | Asahi Kasei Kogyo Kabushiki Kaisha | Process for the preparation of a double-chain plasminogen activator |
US4929444A (en) * | 1985-05-28 | 1990-05-29 | Burroughs Wellcome Co. | Low pH pharmaceutical formulation containing t-PA |
AU569429B2 (en) * | 1985-05-28 | 1988-01-28 | Wellcome Foundation Limited, The | Aqueous acidic tissue plasminogen activator parenternal formulation |
AU7709287A (en) * | 1986-07-16 | 1988-02-10 | Celltech Limited | Process for purifying a plasminogen activator |
JPS6379591A (ja) * | 1986-09-22 | 1988-04-09 | Mitsui Toatsu Chem Inc | tPAの精製方法 |
AU1668988A (en) * | 1987-06-03 | 1988-12-08 | Smithkline Beckman Corporation | Purification of tpa |
DE3726019A1 (de) * | 1987-08-05 | 1989-02-16 | Boehringer Mannheim Gmbh | Verfahren zur abtrennung und reinigung von t-pa |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL8003402A (nl) * | 1980-06-11 | 1982-01-04 | Leuven Res & Dev Vzw | Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking. |
GR79202B (sv) * | 1982-05-05 | 1984-10-22 | Genentech Inc | |
JPS5913732A (ja) * | 1982-07-16 | 1984-01-24 | Mitsui Toatsu Chem Inc | 血栓溶解剤 |
IE81073B1 (en) * | 1986-03-18 | 2000-01-12 | Genentech Inc | Modified human tissue-type plasminogen activator and its preparation |
-
1983
- 1983-10-27 GB GB08414992A patent/GB2138824B/en not_active Expired
- 1983-10-27 CH CH3063/84A patent/CH660742A5/de not_active IP Right Cessation
- 1983-10-27 DE DE19833390272 patent/DE3390272C2/de not_active Expired
- 1983-10-27 WO PCT/JP1983/000386 patent/WO1984001714A1/ja active IP Right Grant
- 1983-10-27 NL NL8320346A patent/NL191755C/xx not_active IP Right Cessation
- 1983-10-27 EP EP83903315A patent/EP0124613B1/en not_active Expired - Lifetime
- 1983-10-28 CA CA000439941A patent/CA1221029A/en not_active Expired
- 1983-10-28 IT IT23533/83A patent/IT1169910B/it active
-
1984
- 1984-06-19 NO NO84842468A patent/NO166314C/no unknown
- 1984-06-22 DK DK307384A patent/DK169686B1/da active
- 1984-06-25 SE SE8403375A patent/SE8403375D0/sv unknown
- 1984-06-29 FI FI842627A patent/FI80597C/sv not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO1984001714A1 (en) | 1984-05-10 |
DK169686B1 (da) | 1995-01-09 |
FI80597C (sv) | 1990-07-10 |
EP0124613B1 (en) | 1992-12-30 |
DK307384A (da) | 1984-06-22 |
EP0124613A1 (en) | 1984-11-14 |
GB2138824A (en) | 1984-10-31 |
NO842468L (no) | 1984-06-19 |
CH660742A5 (de) | 1987-06-15 |
IT8323533A0 (it) | 1983-10-28 |
GB8414992D0 (en) | 1984-07-18 |
FI842627A (fi) | 1984-06-29 |
FI80597B (fi) | 1990-03-30 |
SE8403375D0 (sv) | 1984-06-25 |
EP0124613A4 (en) | 1986-07-29 |
FI842627A0 (fi) | 1984-06-29 |
GB2138824B (en) | 1986-12-31 |
IT1169910B (it) | 1987-06-03 |
NL191755B (nl) | 1996-03-01 |
NO166314C (no) | 1991-07-03 |
DE3390272C2 (de) | 1987-09-17 |
DK307384D0 (da) | 1984-06-22 |
NO166314B (no) | 1991-03-25 |
NL191755C (nl) | 1996-07-02 |
DE3390272T1 (de) | 1984-11-29 |
NL8320346A (nl) | 1984-09-03 |
CA1221029A (en) | 1987-04-28 |
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