NL191755B - Plasminogeenactivator en trombolytisch middel. - Google Patents

Plasminogeenactivator en trombolytisch middel.

Info

Publication number
NL191755B
NL191755B NL8320346A NL8320346A NL191755B NL 191755 B NL191755 B NL 191755B NL 8320346 A NL8320346 A NL 8320346A NL 8320346 A NL8320346 A NL 8320346A NL 191755 B NL191755 B NL 191755B
Authority
NL
Netherlands
Prior art keywords
plasminogen activator
thrombolytic agent
thrombolytic
agent
plasminogen
Prior art date
Application number
NL8320346A
Other languages
English (en)
Other versions
NL8320346A (nl
NL191755C (nl
Original Assignee
Mitsui Toatsu Chemicals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP57189067A external-priority patent/JPS5980613A/ja
Priority claimed from JP57189065A external-priority patent/JPH0637398B2/ja
Application filed by Mitsui Toatsu Chemicals filed Critical Mitsui Toatsu Chemicals
Publication of NL8320346A publication Critical patent/NL8320346A/nl
Publication of NL191755B publication Critical patent/NL191755B/nl
Application granted granted Critical
Publication of NL191755C publication Critical patent/NL191755C/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
NL8320346A 1982-10-29 1983-10-27 Plasminogeenactivator en trombolytisch middel. NL191755C (nl)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP18906782 1982-10-29
JP57189067A JPS5980613A (ja) 1982-10-29 1982-10-29 新規なプラスミノ−ゲン・アクチベ−タ及びその製造方法
JP18906582 1982-10-29
JP57189065A JPH0637398B2 (ja) 1982-10-29 1982-10-29 血栓溶解剤
JP8300386 1983-10-27
PCT/JP1983/000386 WO1984001714A1 (en) 1982-10-29 1983-10-27 Novel plasminogen activator, process for its preparation, and thrombolytic drug containing the same

Publications (3)

Publication Number Publication Date
NL8320346A NL8320346A (nl) 1984-09-03
NL191755B true NL191755B (nl) 1996-03-01
NL191755C NL191755C (nl) 1996-07-02

Family

ID=26505289

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8320346A NL191755C (nl) 1982-10-29 1983-10-27 Plasminogeenactivator en trombolytisch middel.

Country Status (12)

Country Link
EP (1) EP0124613B1 (nl)
CA (1) CA1221029A (nl)
CH (1) CH660742A5 (nl)
DE (1) DE3390272C2 (nl)
DK (1) DK169686B1 (nl)
FI (1) FI80597C (nl)
GB (1) GB2138824B (nl)
IT (1) IT1169910B (nl)
NL (1) NL191755C (nl)
NO (1) NO166314C (nl)
SE (1) SE8403375D0 (nl)
WO (1) WO1984001714A1 (nl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3582338D1 (de) * 1984-01-30 1991-05-08 Asahi Chemical Ind Verfahren zur herstellung eines doppelkettigen plasminogenaktivators.
US4929444A (en) * 1985-05-28 1990-05-29 Burroughs Wellcome Co. Low pH pharmaceutical formulation containing t-PA
BE904831A (fr) * 1985-05-28 1986-11-27 Wellcome Found Composition d'activateur tissulaire du plasminogene.
AU7709287A (en) * 1986-07-16 1988-02-10 Celltech Limited Process for purifying a plasminogen activator
JPS6379591A (ja) * 1986-09-22 1988-04-09 Mitsui Toatsu Chem Inc ｔＰＡの精製方法
AU1668988A (en) * 1987-06-03 1988-12-08 Smithkline Beckman Corporation Purification of tpa
DE3726019A1 (de) * 1987-08-05 1989-02-16 Boehringer Mannheim Gmbh Verfahren zur abtrennung und reinigung von t-pa

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8003402A (nl) * 1980-06-11 1982-01-04 Leuven Res & Dev Vzw Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking.
IL68561A (en) * 1982-05-05 1991-01-31 Genentech Inc Preparation of polypeptide with human tissue plasminogen activator function,processes for making it,and dna and transformed cell intermediates thereof
JPS5913732A (ja) * 1982-07-16 1984-01-24 Mitsui Toatsu Chem Inc 血栓溶解剤
IE81073B1 (en) * 1986-03-18 2000-01-12 Genentech Inc Modified human tissue-type plasminogen activator and its preparation

Also Published As

Publication number Publication date
GB8414992D0 (en) 1984-07-18
DE3390272C2 (de) 1987-09-17
NO166314C (no) 1991-07-03
FI842627A0 (fi) 1984-06-29
DK169686B1 (da) 1995-01-09
CA1221029A (en) 1987-04-28
GB2138824A (en) 1984-10-31
FI80597C (fi) 1990-07-10
DK307384A (da) 1984-06-22
FI842627A (fi) 1984-06-29
NO842468L (no) 1984-06-19
NL8320346A (nl) 1984-09-03
IT8323533A0 (it) 1983-10-28
SE8403375L (sv) 1984-06-25
EP0124613A4 (en) 1986-07-29
GB2138824B (en) 1986-12-31
CH660742A5 (de) 1987-06-15
EP0124613A1 (en) 1984-11-14
SE8403375D0 (sv) 1984-06-25
DE3390272T1 (de) 1984-11-29
WO1984001714A1 (en) 1984-05-10
EP0124613B1 (en) 1992-12-30
NO166314B (no) 1991-03-25
NL191755C (nl) 1996-07-02
DK307384D0 (da) 1984-06-22
IT1169910B (it) 1987-06-03
FI80597B (fi) 1990-03-30

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Legal Events

Date Code Title Description
A1A A request for search or an international-type search has been filed
BB A search report has been drawn up
A85 Still pending on 85-01-01
BC A request for examination has been filed
SNR Assignments of patents or rights arising from examined patent applications

Owner name: MITSUI CHEMICALS, INC.

SNR Assignments of patents or rights arising from examined patent applications

Owner name: SCHERING AKTIENGESELLSCHAFT

V1 Lapsed because of non-payment of the annual fee

Effective date: 20020501