FR2201867A1 - Chromatographic extraction of urokinase - by treating human urine extract on cellulose deae type resin - Google Patents
Chromatographic extraction of urokinase - by treating human urine extract on cellulose deae type resinInfo
- Publication number
- FR2201867A1 FR2201867A1 FR7227703A FR7227703A FR2201867A1 FR 2201867 A1 FR2201867 A1 FR 2201867A1 FR 7227703 A FR7227703 A FR 7227703A FR 7227703 A FR7227703 A FR 7227703A FR 2201867 A1 FR2201867 A1 FR 2201867A1
- Authority
- FR
- France
- Prior art keywords
- urokinase
- type resin
- human urine
- treating human
- urine extract
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
Human urine extract is subjected to exclusion chromatograpy on cellulose DEAE type resin at pH 4.5, the supernatant liquid then being treated on the same resin at pH 7.0 then purified to give a urokinase soln. suitable as a thrombolytic agent.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7227703A FR2201867A1 (en) | 1972-08-01 | 1972-08-01 | Chromatographic extraction of urokinase - by treating human urine extract on cellulose deae type resin |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7227703A FR2201867A1 (en) | 1972-08-01 | 1972-08-01 | Chromatographic extraction of urokinase - by treating human urine extract on cellulose deae type resin |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2201867A1 true FR2201867A1 (en) | 1974-05-03 |
FR2201867B1 FR2201867B1 (en) | 1975-10-17 |
Family
ID=9102685
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7227703A Granted FR2201867A1 (en) | 1972-08-01 | 1972-08-01 | Chromatographic extraction of urokinase - by treating human urine extract on cellulose deae type resin |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2201867A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2395275A1 (en) * | 1977-03-10 | 1979-01-19 | Sumitomo Chemical Co | UROKINASE PURIFICATION PROCESS |
-
1972
- 1972-08-01 FR FR7227703A patent/FR2201867A1/en active Granted
Non-Patent Citations (1)
Title |
---|
NEANT * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2395275A1 (en) * | 1977-03-10 | 1979-01-19 | Sumitomo Chemical Co | UROKINASE PURIFICATION PROCESS |
Also Published As
Publication number | Publication date |
---|---|
FR2201867B1 (en) | 1975-10-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
JD | Different final judgements | ||
ST | Notification of lapse |