SE461735B - Nya mitomycin-analoger samt foerfarande foer framstaellning daerav - Google Patents

Nya mitomycin-analoger samt foerfarande foer framstaellning daerav

Info

Publication number
SE461735B
SE461735B SE8401999A SE8401999A SE461735B SE 461735 B SE461735 B SE 461735B SE 8401999 A SE8401999 A SE 8401999A SE 8401999 A SE8401999 A SE 8401999A SE 461735 B SE461735 B SE 461735B
Authority
SE
Sweden
Prior art keywords
ethylamine
methoxymitosane
formula
compound
carbon atoms
Prior art date
Application number
SE8401999A
Other languages
English (en)
Swedish (sv)
Other versions
SE8401999D0 (sv
SE8401999L (sv
Inventor
D M Vyas
T W Doyle
Y Chiang
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of SE8401999D0 publication Critical patent/SE8401999D0/xx
Publication of SE8401999L publication Critical patent/SE8401999L/xx
Publication of SE461735B publication Critical patent/SE461735B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SE8401999A 1983-04-11 1984-04-10 Nya mitomycin-analoger samt foerfarande foer framstaellning daerav SE461735B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48401683A 1983-04-11 1983-04-11
US06/581,291 US4803212A (en) 1983-04-11 1984-02-24 Amino disulfides

Publications (3)

Publication Number Publication Date
SE8401999D0 SE8401999D0 (sv) 1984-04-10
SE8401999L SE8401999L (sv) 1984-10-12
SE461735B true SE461735B (sv) 1990-03-19

Family

ID=27047825

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8401999A SE461735B (sv) 1983-04-11 1984-04-10 Nya mitomycin-analoger samt foerfarande foer framstaellning daerav

Country Status (23)

Country Link
US (1) US4803212A (pt)
KR (1) KR890001488B1 (pt)
AT (1) AT387019B (pt)
AU (1) AU577523B2 (pt)
CA (1) CA1285567C (pt)
CH (1) CH661273A5 (pt)
CY (1) CY1533A (pt)
DE (1) DE3413489A1 (pt)
DK (1) DK170071B1 (pt)
ES (1) ES8602798A1 (pt)
FI (1) FI78701C (pt)
FR (1) FR2543953B1 (pt)
GB (1) GB2140799B (pt)
GR (1) GR79579B (pt)
HK (1) HK82690A (pt)
IE (1) IE57348B1 (pt)
IT (1) IT1176003B (pt)
LU (1) LU85295A1 (pt)
MX (1) MX9202850A (pt)
MY (1) MY102071A (pt)
NL (1) NL8401104A (pt)
PT (1) PT78399B (pt)
SE (1) SE461735B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4487769A (en) * 1982-06-04 1984-12-11 Bristol-Myers Company Amidines
US4866180A (en) * 1984-02-24 1989-09-12 Bristol-Myers Company Amino disulfide thiol exchange products
JPS60255789A (ja) * 1984-06-01 1985-12-17 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体，その製造法および抗腫瘍剤
AU581673B2 (en) * 1984-09-04 1989-03-02 Bristol-Myers Company Substituted 7-oxomitosanes
US4927943A (en) * 1984-09-04 1990-05-22 Bristol-Myers Company Substituted 7-oxomitosanes
US4888341A (en) * 1984-09-04 1989-12-19 University Patents, Inc. 6-substituted mitomycin analogs
DE3674043D1 (de) * 1985-04-10 1990-10-18 Kyowa Hakko Kogyo Kk Pharmakologisch aktive mitomycinderivate.
JPS6354380A (ja) * 1986-08-26 1988-03-08 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体
JPS63150282A (ja) * 1986-12-13 1988-06-22 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体
ZA886812B (en) * 1987-11-23 1989-07-26 Bristol Myers Co Anti-tumor prodrugs
US5075454A (en) * 1990-03-08 1991-12-24 Bristol-Myers Squibb Company 7-(diphenylmethyl)oxy-9a-methoxymitosane
US5175303A (en) * 1990-03-08 1992-12-29 Bristol-Myers Squibb Company Preparation of 7-(diphenylmethyl)oxy-9A-methoxymitosane

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3660578A (en) * 1957-04-06 1972-05-02 Kyowa Hakko Kogyo Kk Mitomycin c
NL129868C (pt) * 1963-06-07
DE1570029A1 (de) * 1964-07-09 1970-04-09 Kyowa Hakko Kogyo Kk Verfahren zur Herstellung von Mitosanverbindungen
NL130086C (pt) * 1964-07-14 1970-06-15
US3332944A (en) * 1964-11-02 1967-07-25 American Cyanamid Co Antibiotic derivatives of mitomycins a, b, c and porfiromycin
JPS5439098A (en) * 1977-08-31 1979-03-24 Kyowa Hakko Kogyo Co Ltd Mitomycin c derivatives
US4268676A (en) * 1979-12-05 1981-05-19 University Patents, Inc. Mitomycin analogs
GB2093643A (en) * 1981-02-17 1982-09-02 Standard Telephones Cables Ltd DC-to-DC converter
NZ199617A (en) * 1981-05-15 1985-08-30 University Patents Inc Azirino(2',3',:3,4)pyrrolo(1,2-a)indole-4,7-dione derivatives and pharmaceutical compositions
US4487769A (en) * 1982-06-04 1984-12-11 Bristol-Myers Company Amidines
DE3376114D1 (en) * 1982-12-07 1988-05-05 Kyowa Hakko Kogyo Kk Mitomycin analogues
US4642352A (en) * 1983-12-23 1987-02-10 Bristol-Myers Company Acylamino mitosanes
AU581673B2 (en) * 1984-09-04 1989-03-02 Bristol-Myers Company Substituted 7-oxomitosanes

Also Published As

Publication number Publication date
IT1176003B (it) 1987-08-12
DE3413489A1 (de) 1984-10-11
GB2140799B (en) 1987-04-08
FI841380A0 (fi) 1984-04-06
IE840878L (en) 1984-10-11
GB2140799A (en) 1984-12-05
DK183984D0 (da) 1984-04-09
GR79579B (pt) 1984-10-30
HK82690A (en) 1990-10-19
DK183984A (da) 1984-10-12
FR2543953A1 (fr) 1984-10-12
CY1533A (en) 1990-11-16
PT78399B (en) 1986-07-17
US4803212A (en) 1989-02-07
AT387019B (de) 1988-11-25
FI841380A (fi) 1984-10-12
GB8409242D0 (en) 1984-05-23
IT8420478A0 (it) 1984-04-10
SE8401999D0 (sv) 1984-04-10
AU577523B2 (en) 1988-09-29
SE8401999L (sv) 1984-10-12
DK170071B1 (da) 1995-05-15
MX9202850A (es) 1992-06-30
CH661273A5 (de) 1987-07-15
ES531338A0 (es) 1985-12-01
IE57348B1 (en) 1992-08-12
NL8401104A (nl) 1984-11-01
CA1285567C (en) 1991-07-02
FR2543953B1 (fr) 1988-08-26
LU85295A1 (fr) 1984-11-28
MY102071A (en) 1992-03-31
FI78701C (fi) 1989-09-11
FI78701B (fi) 1989-05-31
DE3413489C2 (pt) 1991-07-25
ES8602798A1 (es) 1985-12-01
ATA122384A (de) 1988-04-15
PT78399A (en) 1984-05-01
AU2595184A (en) 1984-10-18
KR890001488B1 (ko) 1989-05-04

Similar Documents

Publication Publication Date Title
SE461735B (sv) Nya mitomycin-analoger samt foerfarande foer framstaellning daerav
US6306849B1 (en) Selected derivatives of K-252a
US4866180A (en) Amino disulfide thiol exchange products
FI78700C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara mitosanderivat.
EP4137484A1 (en) Tricyclic compounds as egfr inhibitors
US4691023A (en) Amino disulfides
NO169441B (no) Fremgangsmaate til fremstilling av 7-oksomitosanderivater
Lin et al. (o-and p-nitrobenzyloxycarbonyl)-5-fluorouracil derivatives as potential conjugated bioreductive alkylating agents
US4567256A (en) Amidine process
US4652644A (en) Process for preparation of N7 -amidino substituted mitomycin C derivatives
JPS59205382A (ja) アミノ２硫化物
JPH0472838B2 (pt)
Mostafa Synthesis of 1, 4-diazine-fused and phosphorus containing stable nitroxide free radicals
AT397091B (de) Verfahren zur herstellung von neuen mitosan-derivaten
CZ34625U1 (cs) Inhibitory purinnukleosidfosforylasy k léčení T-buněčné akutní lymfoblastické leukémie a lymfomů
AT397092B (de) Verfahren zur herstellung von neuen mitosan-derivaten
CZ309199B6 (cs) Inhibitory purinnukleosidfosforylasy, jejich příprava a použití k léčení T-buněčné akutní lymfoblastické leukémie a lymfomů
NO881204L (no) Mitosanderivater.

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8401999-1

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 8401999-1

Format of ref document f/p: F