DK170071B1 - Mitomycinderivater samt fremgangsmåde til femstilling deraf - Google Patents

Mitomycinderivater samt fremgangsmåde til femstilling deraf Download PDF

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Publication number
DK170071B1
DK170071B1 DK183984A DK183984A DK170071B1 DK 170071 B1 DK170071 B1 DK 170071B1 DK 183984 A DK183984 A DK 183984A DK 183984 A DK183984 A DK 183984A DK 170071 B1 DK170071 B1 DK 170071B1
Authority
DK
Denmark
Prior art keywords
ethylamino
compound according
methoxymitosan
phenyl
carbon atoms
Prior art date
Application number
DK183984A
Other languages
Danish (da)
English (en)
Other versions
DK183984A (da
DK183984D0 (da
Inventor
Dolatrai Mohanlal Vyas
Terrence William Doyle
Yulin Chiang
Original Assignee
Squibb Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb Bristol Myers Co filed Critical Squibb Bristol Myers Co
Publication of DK183984D0 publication Critical patent/DK183984D0/da
Publication of DK183984A publication Critical patent/DK183984A/da
Application granted granted Critical
Publication of DK170071B1 publication Critical patent/DK170071B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK183984A 1983-04-11 1984-04-09 Mitomycinderivater samt fremgangsmåde til femstilling deraf DK170071B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US48401683A 1983-04-11 1983-04-11
US48401683 1983-04-11
US06/581,291 US4803212A (en) 1983-04-11 1984-02-24 Amino disulfides
US58129184 1984-02-24

Publications (3)

Publication Number Publication Date
DK183984D0 DK183984D0 (da) 1984-04-09
DK183984A DK183984A (da) 1984-10-12
DK170071B1 true DK170071B1 (da) 1995-05-15

Family

ID=27047825

Family Applications (1)

Application Number Title Priority Date Filing Date
DK183984A DK170071B1 (da) 1983-04-11 1984-04-09 Mitomycinderivater samt fremgangsmåde til femstilling deraf

Country Status (23)

Country Link
US (1) US4803212A (pt)
KR (1) KR890001488B1 (pt)
AT (1) AT387019B (pt)
AU (1) AU577523B2 (pt)
CA (1) CA1285567C (pt)
CH (1) CH661273A5 (pt)
CY (1) CY1533A (pt)
DE (1) DE3413489A1 (pt)
DK (1) DK170071B1 (pt)
ES (1) ES8602798A1 (pt)
FI (1) FI78701C (pt)
FR (1) FR2543953B1 (pt)
GB (1) GB2140799B (pt)
GR (1) GR79579B (pt)
HK (1) HK82690A (pt)
IE (1) IE57348B1 (pt)
IT (1) IT1176003B (pt)
LU (1) LU85295A1 (pt)
MX (1) MX9202850A (pt)
MY (1) MY102071A (pt)
NL (1) NL8401104A (pt)
PT (1) PT78399B (pt)
SE (1) SE461735B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4487769A (en) * 1982-06-04 1984-12-11 Bristol-Myers Company Amidines
US4866180A (en) * 1984-02-24 1989-09-12 Bristol-Myers Company Amino disulfide thiol exchange products
JPS60255789A (ja) * 1984-06-01 1985-12-17 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体，その製造法および抗腫瘍剤
AU581673B2 (en) * 1984-09-04 1989-03-02 Bristol-Myers Company Substituted 7-oxomitosanes
US4927943A (en) * 1984-09-04 1990-05-22 Bristol-Myers Company Substituted 7-oxomitosanes
US4888341A (en) * 1984-09-04 1989-12-19 University Patents, Inc. 6-substituted mitomycin analogs
DE3674043D1 (de) * 1985-04-10 1990-10-18 Kyowa Hakko Kogyo Kk Pharmakologisch aktive mitomycinderivate.
JPS6354380A (ja) * 1986-08-26 1988-03-08 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体
JPS63150282A (ja) * 1986-12-13 1988-06-22 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体
ZA886812B (en) * 1987-11-23 1989-07-26 Bristol Myers Co Anti-tumor prodrugs
US5075454A (en) * 1990-03-08 1991-12-24 Bristol-Myers Squibb Company 7-(diphenylmethyl)oxy-9a-methoxymitosane
US5175303A (en) * 1990-03-08 1992-12-29 Bristol-Myers Squibb Company Preparation of 7-(diphenylmethyl)oxy-9A-methoxymitosane

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3660578A (en) * 1957-04-06 1972-05-02 Kyowa Hakko Kogyo Kk Mitomycin c
NL129868C (pt) * 1963-06-07
DE1570029A1 (de) * 1964-07-09 1970-04-09 Kyowa Hakko Kogyo Kk Verfahren zur Herstellung von Mitosanverbindungen
NL130086C (pt) * 1964-07-14 1970-06-15
US3332944A (en) * 1964-11-02 1967-07-25 American Cyanamid Co Antibiotic derivatives of mitomycins a, b, c and porfiromycin
JPS5439098A (en) * 1977-08-31 1979-03-24 Kyowa Hakko Kogyo Co Ltd Mitomycin c derivatives
US4268676A (en) * 1979-12-05 1981-05-19 University Patents, Inc. Mitomycin analogs
GB2093643A (en) * 1981-02-17 1982-09-02 Standard Telephones Cables Ltd DC-to-DC converter
NZ199617A (en) * 1981-05-15 1985-08-30 University Patents Inc Azirino(2',3',:3,4)pyrrolo(1,2-a)indole-4,7-dione derivatives and pharmaceutical compositions
US4487769A (en) * 1982-06-04 1984-12-11 Bristol-Myers Company Amidines
EP0116208B1 (en) * 1982-12-07 1988-03-30 Kyowa Hakko Kogyo Co., Ltd. Mitomycin analogues
US4642352A (en) * 1983-12-23 1987-02-10 Bristol-Myers Company Acylamino mitosanes
AU581673B2 (en) * 1984-09-04 1989-03-02 Bristol-Myers Company Substituted 7-oxomitosanes

Also Published As

Publication number Publication date
SE8401999L (sv) 1984-10-12
DK183984A (da) 1984-10-12
IT1176003B (it) 1987-08-12
HK82690A (en) 1990-10-19
IE840878L (en) 1984-10-11
MX9202850A (es) 1992-06-30
ATA122384A (de) 1988-04-15
FI78701B (fi) 1989-05-31
GR79579B (pt) 1984-10-30
DE3413489A1 (de) 1984-10-11
AU2595184A (en) 1984-10-18
AU577523B2 (en) 1988-09-29
FI841380A0 (fi) 1984-04-06
FR2543953A1 (fr) 1984-10-12
KR890001488B1 (ko) 1989-05-04
SE8401999D0 (sv) 1984-04-10
DE3413489C2 (pt) 1991-07-25
CY1533A (en) 1990-11-16
MY102071A (en) 1992-03-31
PT78399A (en) 1984-05-01
DK183984D0 (da) 1984-04-09
IE57348B1 (en) 1992-08-12
FR2543953B1 (fr) 1988-08-26
ES531338A0 (es) 1985-12-01
NL8401104A (nl) 1984-11-01
FI78701C (fi) 1989-09-11
GB2140799B (en) 1987-04-08
IT8420478A0 (it) 1984-04-10
PT78399B (en) 1986-07-17
US4803212A (en) 1989-02-07
ES8602798A1 (es) 1985-12-01
AT387019B (de) 1988-11-25
CA1285567C (en) 1991-07-02
FI841380A (fi) 1984-10-12
LU85295A1 (fr) 1984-11-28
CH661273A5 (de) 1987-07-15
GB8409242D0 (en) 1984-05-23
SE461735B (sv) 1990-03-19
GB2140799A (en) 1984-12-05

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed