SE450573B - 1h-pyrazolo/1,5-a/pyrimidiner, framstellning derav och farmaceutisk komposition - Google Patents
1h-pyrazolo/1,5-a/pyrimidiner, framstellning derav och farmaceutisk kompositionInfo
- Publication number
- SE450573B SE450573B SE8301412A SE8301412A SE450573B SE 450573 B SE450573 B SE 450573B SE 8301412 A SE8301412 A SE 8301412A SE 8301412 A SE8301412 A SE 8301412A SE 450573 B SE450573 B SE 450573B
- Authority
- SE
- Sweden
- Prior art keywords
- alkyl
- formula
- phenyl
- compound
- pyridyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8207637 | 1982-03-16 | ||
GB838303089A GB8303089D0 (en) | 1983-02-04 | 1983-02-04 | Substituted 1h-pyrazolo 1,5-a pyrimidines |
Publications (3)
Publication Number | Publication Date |
---|---|
SE8301412D0 SE8301412D0 (sv) | 1983-03-15 |
SE8301412L SE8301412L (sv) | 1983-09-17 |
SE450573B true SE450573B (sv) | 1987-07-06 |
Family
ID=26282260
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8301412A SE450573B (sv) | 1982-03-16 | 1983-03-15 | 1h-pyrazolo/1,5-a/pyrimidiner, framstellning derav och farmaceutisk komposition |
Country Status (13)
Country | Link |
---|---|
US (1) | US4482555A (fr) |
AU (1) | AU557300B2 (fr) |
CA (1) | CA1192546A (fr) |
CH (1) | CH654306A5 (fr) |
DE (1) | DE3309432A1 (fr) |
DK (1) | DK120783A (fr) |
FI (1) | FI74469C (fr) |
FR (1) | FR2523582B1 (fr) |
IL (1) | IL68133A (fr) |
IT (1) | IT1194555B (fr) |
NL (1) | NL8300934A (fr) |
SE (1) | SE450573B (fr) |
SU (1) | SU1366060A3 (fr) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6245759B1 (en) * | 1999-03-11 | 2001-06-12 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
MY125533A (en) | 1999-12-06 | 2006-08-30 | Bristol Myers Squibb Co | Heterocyclic dihydropyrimidine compounds |
EP1782859A3 (fr) * | 2003-04-11 | 2009-09-30 | High Point Pharmaceuticals, LLC | Utilisation thérapeutique de pyrazolo [1,5- a] pyrimidines |
EP1615697A2 (fr) * | 2003-04-11 | 2006-01-18 | Novo Nordisk A/S | Utilisation pharmaceutique de pyrazolo 1,5-a]pyrimidines substituees |
US7772232B2 (en) | 2004-04-15 | 2010-08-10 | Bristol-Myers Squibb Company | Quinazolinyl compounds as inhibitors of potassium channel function |
WO2006040329A1 (fr) * | 2004-10-12 | 2006-04-20 | Novo Nordisk A/S | Composes spiro actifs du type a- hydroxysteroide deshydrogenase de type 1 |
EP1945207A2 (fr) * | 2005-11-01 | 2008-07-23 | Transtech Pharma, Inc. | Utilisation pharmaceutique des amides substitués |
JP2009514818A (ja) * | 2005-11-01 | 2009-04-09 | ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー | 置換アミドの製薬学的用途 |
WO2007107550A1 (fr) * | 2006-03-21 | 2007-09-27 | High Point Pharmaceuticals, Llc | Dérivés d'adamantane pour le traitement du syndrome métabolique |
BRPI0710669A2 (pt) | 2006-04-07 | 2011-08-16 | High Point Pharmaceuticals Llc | compostos ativos de dehidrogenase de 11b-hidroxiesteróide tipo 1 |
EP2038255A2 (fr) * | 2006-06-16 | 2009-03-25 | High Point Pharmaceuticals, LLC | Utilisation pharmaceutique de piperidines carboxamides substitués |
EP1878721A1 (fr) * | 2006-07-13 | 2008-01-16 | Novo Nordisk A/S | 4-Piperidylbenzamides en tant qu'inhibiteurs de la 11-beta-hydroxysteroid dehydrogenase type 1 |
US8048908B2 (en) * | 2006-07-13 | 2011-11-01 | High Point Pharmaceuticals, Llc | 11β-hydroxysteroid dehydrogenase type 1 active compounds |
US8334305B2 (en) * | 2007-02-23 | 2012-12-18 | High Point Pharmaceuticals, Llc | N-adamantyl benzamides as inhibitors of 11-β-hydroxysteroid dehydrogenase |
JP2010519240A (ja) * | 2007-02-23 | 2010-06-03 | ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー | 11−ベータ−ヒドロキシステロイドデヒドロゲナーゼの阻害剤としての、n−アダマンチルベンズアミド |
BRPI0806847A2 (pt) | 2007-02-23 | 2014-04-29 | High Point Pharmaceuticals Llc | N-adamantil benzamidas como inibidores de 11-beta-hidroxiesteróide desidrogenase |
US20110003852A1 (en) * | 2007-02-23 | 2011-01-06 | Soren Ebdrup | N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase |
EP2134705A1 (fr) * | 2007-03-09 | 2009-12-23 | High Point Pharmaceuticals, LLC | Indole- et benzimidazole amides comme inhibiteurs des hydroxystéroïde déshydrogénases |
JP2010522766A (ja) * | 2007-03-28 | 2010-07-08 | ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー | 11ベータ−hsd1活性化合物 |
WO2008127924A1 (fr) * | 2007-04-11 | 2008-10-23 | High Point Pharmaceuticals, Llc. | Nouveaux composés |
ES2393230T3 (es) * | 2007-04-24 | 2012-12-19 | High Point Pharmaceuticals, Llc | Uso farmacéutico de amidas sustituidas |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3907799A (en) * | 1971-08-16 | 1975-09-23 | Icn Pharmaceuticals | Xanthine oxidase inhibitors |
BE786611A (fr) * | 1971-08-16 | 1973-01-22 | Int Chem & Nuclear Corp | Nouveaux inhibiteurs de xanthine-oxydase et leur procede de preparatio |
BE792533A (fr) * | 1971-12-09 | 1973-06-08 | Int Chem & Nuclear Corp | Nouvelles pyrazolo (1,5a) pyrimidines et leur procede de preparation |
US3925385A (en) * | 1972-04-20 | 1975-12-09 | Icn Pharmaceuticals | 6-Carbethoxy-3,7-disubstitutedpyrazolo{8 1,5a{9 pyrimidines |
US4093617A (en) * | 1974-11-12 | 1978-06-06 | Icn Pharmaceuticals, Inc. | 3,5,7-Trisubstituted pyrazolo[1,5-a]pyrimidines |
US4048184A (en) * | 1976-11-15 | 1977-09-13 | E. R. Squibb & Sons, Inc. | 6-Phenyl-2H-pyrazolo[3,4-b]pyridines |
US4281000A (en) * | 1979-07-09 | 1981-07-28 | American Cyanamid Company | Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents |
-
1983
- 1983-03-09 AU AU12304/83A patent/AU557300B2/en not_active Ceased
- 1983-03-10 US US06/474,205 patent/US4482555A/en not_active Expired - Fee Related
- 1983-03-11 CH CH1325/83A patent/CH654306A5/de not_active IP Right Cessation
- 1983-03-11 IT IT20024/83A patent/IT1194555B/it active
- 1983-03-15 NL NL8300934A patent/NL8300934A/xx active Search and Examination
- 1983-03-15 CA CA000423644A patent/CA1192546A/fr not_active Expired
- 1983-03-15 SU SU833565748A patent/SU1366060A3/ru active
- 1983-03-15 FI FI830864A patent/FI74469C/fi not_active IP Right Cessation
- 1983-03-15 IL IL68133A patent/IL68133A/xx unknown
- 1983-03-15 DK DK120783A patent/DK120783A/da not_active Application Discontinuation
- 1983-03-15 SE SE8301412A patent/SE450573B/sv not_active IP Right Cessation
- 1983-03-15 FR FR8304253A patent/FR2523582B1/fr not_active Expired
- 1983-03-16 DE DE19833309432 patent/DE3309432A1/de not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
DK120783A (da) | 1983-09-17 |
FR2523582A1 (fr) | 1983-09-23 |
IL68133A (en) | 1985-12-31 |
FI830864A0 (fi) | 1983-03-15 |
CH654306A5 (de) | 1986-02-14 |
FI830864L (fi) | 1983-09-17 |
SU1366060A3 (ru) | 1988-01-07 |
SE8301412D0 (sv) | 1983-03-15 |
NL8300934A (nl) | 1983-10-17 |
AU557300B2 (en) | 1986-12-18 |
FR2523582B1 (fr) | 1985-12-06 |
US4482555A (en) | 1984-11-13 |
IL68133A0 (en) | 1983-06-15 |
SE8301412L (sv) | 1983-09-17 |
DK120783D0 (da) | 1983-03-15 |
CA1192546A (fr) | 1985-08-27 |
AU1230483A (en) | 1983-09-22 |
DE3309432A1 (de) | 1983-09-22 |
FI74469B (fi) | 1987-10-30 |
FI74469C (fi) | 1988-02-08 |
IT8320024A0 (it) | 1983-03-11 |
IT1194555B (it) | 1988-09-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
NUG | Patent has lapsed |
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