SE449100B - N-((4-fenyl-1,2,3,6-tetrahydropyridin-1-yl)alkylen)azaspiroalkandioner, forfarande for deras framstellning och farmaceutisk komposition derav - Google Patents

N-((4-fenyl-1,2,3,6-tetrahydropyridin-1-yl)alkylen)azaspiroalkandioner, forfarande for deras framstellning och farmaceutisk komposition derav

Info

Publication number
SE449100B
SE449100B SE8201630A SE8201630A SE449100B SE 449100 B SE449100 B SE 449100B SE 8201630 A SE8201630 A SE 8201630A SE 8201630 A SE8201630 A SE 8201630A SE 449100 B SE449100 B SE 449100B
Authority
SE
Sweden
Prior art keywords
formula
carbon atoms
compound
tetrahydropyridin
butyl
Prior art date
Application number
SE8201630A
Other languages
English (en)
Swedish (sv)
Other versions
SE8201630L (sv
Inventor
Jr D L Temple
J P Yevich
Jr W G Lobeck
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of SE8201630L publication Critical patent/SE8201630L/xx
Publication of SE449100B publication Critical patent/SE449100B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
SE8201630A 1981-03-16 1982-03-15 N-((4-fenyl-1,2,3,6-tetrahydropyridin-1-yl)alkylen)azaspiroalkandioner, forfarande for deras framstellning och farmaceutisk komposition derav SE449100B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/244,426 US4320131A (en) 1981-03-16 1981-03-16 N-[(4-Phenyl-1,2,3,6-tetrahydropyridin-1-yl)alkylene]azaspiroalkanediones and N-[(4-hydroxy-4-phenylpiperidin-1-yl)alkylene]azaspiroalkanediones

Publications (2)

Publication Number Publication Date
SE8201630L SE8201630L (sv) 1982-09-17
SE449100B true SE449100B (sv) 1987-04-06

Family

ID=22922718

Family Applications (2)

Application Number Title Priority Date Filing Date
SE8201630A SE449100B (sv) 1981-03-16 1982-03-15 N-((4-fenyl-1,2,3,6-tetrahydropyridin-1-yl)alkylen)azaspiroalkandioner, forfarande for deras framstellning och farmaceutisk komposition derav
SE8603177A SE460606B (sv) 1981-03-16 1986-07-21 N-(4-hydroxi-4-fenylpiperidin-1-yl) alkylen azaspiroalkandioner

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE8603177A SE460606B (sv) 1981-03-16 1986-07-21 N-(4-hydroxi-4-fenylpiperidin-1-yl) alkylen azaspiroalkandioner

Country Status (31)

Country Link
US (1) US4320131A (fr)
JP (1) JPS57165384A (fr)
KR (1) KR880001557B1 (fr)
AT (1) AT381939B (fr)
AU (1) AU535385B2 (fr)
BE (1) BE892502A (fr)
CA (1) CA1192556A (fr)
CH (2) CH652123A5 (fr)
CY (1) CY1372A (fr)
DE (1) DE3209534A1 (fr)
DK (1) DK161322C (fr)
ES (1) ES8305753A1 (fr)
FI (1) FI71317C (fr)
FR (1) FR2501689B1 (fr)
GB (1) GB2094801B (fr)
GR (1) GR76113B (fr)
HK (1) HK4688A (fr)
HU (2) HU193379B (fr)
IE (1) IE52789B1 (fr)
IL (1) IL65254A0 (fr)
IT (1) IT1148145B (fr)
KE (1) KE3710A (fr)
LU (1) LU84012A1 (fr)
NL (1) NL8201022A (fr)
NZ (1) NZ199944A (fr)
PH (1) PH18182A (fr)
PT (1) PT74584B (fr)
SE (2) SE449100B (fr)
SG (1) SG30887G (fr)
YU (1) YU43789B (fr)
ZA (1) ZA821541B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2660407B2 (ja) * 1986-09-26 1997-10-08 住友製薬株式会社 新規なイミド誘導体
HU207310B (en) * 1988-12-02 1993-03-29 Pfizer Process for producing aryl-piperidine derivatives
US5137894A (en) * 1991-12-05 1992-08-11 New James S 4-(4-Piperidinyl-thieno[3,2-c]pyridine derivatives of n-alkylglutarimides

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US355877A (en) * 1887-01-11 Waltee n
FR3013E (fr) * 1902-04-03 1904-08-12 William Henry Hoyle Perfectionnements au procédé et aux machines pour la fabrication de matières fibreuses connues sous le nom de fils "frottés"
US3106552A (en) * 1960-07-19 1963-10-08 Geschickter Fund Med Res Nu-substituted azaspiranes and azaspirane-diones and processes for their preparation
US3432499A (en) * 1965-04-02 1969-03-11 Geschickter Fund Med Res Trifluoromethylazaspiranes and azaspirane diones
US3398151A (en) * 1966-02-01 1968-08-20 Mead Johnson & Co Azaspirodecanediones and azaspiroundecanediones
US3558777A (en) * 1968-06-21 1971-01-26 Mead Johnson & Co Pharmacologic processes and compositions containing azaspirodecanediones and azaspiroundecanediones
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
CH547802A (de) * 1970-06-19 1974-04-11 Hoffmann La Roche Verfahren zur herstellung von tetrahydropyridinderivaten.
US3976776A (en) * 1972-12-06 1976-08-24 Mead Johnson & Company Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones
US4250175A (en) * 1977-10-31 1981-02-10 Mccall John M Methods of treating psychosis
US4179510A (en) * 1977-10-31 1979-12-18 The Upjohn Company Methods of treating psychosis
US4218456A (en) * 1978-07-10 1980-08-19 Warner-Lambert Company 1-(4-Fluorophenyl)-4-(1,2,3,6-tetrahydro-4-phenoxy-1-pyridinyl)-butanones
US4261990A (en) * 1979-03-09 1981-04-14 Ciba-Geigy Corporation N-alkyleneiminoalkyl-dicarboximides as antiallergics and antiasthmatics
US4221714A (en) * 1979-08-03 1980-09-09 American Cyanamid Company 11-(1,2,3,6-Tetrahydro-substituted-4-pyridyl)-dibenz[b,f][1,4]oxazepines
US4305944A (en) * 1980-09-08 1981-12-15 Mead Johnson & Company N-[(4-[3-cyano substituted pyridyl]piperazino)alkyl]-azaspirodecanediones

Also Published As

Publication number Publication date
CA1192556A (fr) 1985-08-27
DK161322C (da) 1991-12-09
IL65254A0 (en) 1982-05-31
LU84012A1 (fr) 1983-02-22
PH18182A (en) 1985-04-12
PT74584A (en) 1982-04-01
GB2094801B (en) 1985-04-24
ES510448A0 (es) 1983-04-16
US4320131A (en) 1982-03-16
CH652123A5 (de) 1985-10-31
AT381939B (de) 1986-12-10
HU190793B (en) 1986-11-28
NL8201022A (nl) 1982-10-18
KR830008680A (ko) 1983-12-14
FI820855L (fi) 1982-09-17
KR880001557B1 (ko) 1988-08-22
DE3209534A1 (de) 1982-09-23
PT74584B (pt) 1984-11-27
IE820590L (en) 1982-09-16
CY1372A (en) 1987-08-07
HK4688A (en) 1988-01-29
SE8201630L (sv) 1982-09-17
YU55882A (en) 1984-10-31
FI71317B (fi) 1986-09-09
GB2094801A (en) 1982-09-22
CH657365A5 (de) 1986-08-29
FR2501689B1 (fr) 1985-07-19
SE460606B (sv) 1989-10-30
IE52789B1 (en) 1988-03-02
SG30887G (en) 1987-07-17
AU8133582A (en) 1982-11-04
HU193379B (en) 1987-09-28
YU43789B (en) 1989-12-31
JPH0345072B2 (fr) 1991-07-09
DK112682A (da) 1982-09-17
ES8305753A1 (es) 1983-04-16
HUT40797A (en) 1987-02-27
NZ199944A (en) 1986-06-11
BE892502A (fr) 1982-09-15
AU535385B2 (en) 1984-03-15
IT1148145B (it) 1986-11-26
DE3209534C2 (fr) 1993-03-11
FR2501689A1 (fr) 1982-09-17
SE8603177D0 (sv) 1986-07-21
ZA821541B (en) 1983-01-26
ATA104682A (de) 1986-05-15
JPS57165384A (en) 1982-10-12
IT8247992A0 (it) 1982-03-15
KE3710A (en) 1987-04-16
FI71317C (fi) 1986-12-19
GR76113B (fr) 1984-08-03
SE8603177L (sv) 1986-07-21
DK161322B (da) 1991-06-24

Similar Documents

Publication Publication Date Title
US6069254A (en) Carboxamide derivatives of piperidine for the treatment of thrombosis disorders
SE449748B (sv) 2-(4-((4,4-dialkyl-2,6-piperidindion-1-yl)butyl)-1-piperazinyl)pyridiner, deras framstellning och farmaceutiska komposition
DE3522579C2 (de) Neue 1,4-Dihydropyridin-Derivate und Salze derselben, Verfahren zur Herstellung derselben und pharmazeutische Mittel mit einem Gehalt derselben
JP3269574B2 (ja) メタノアントラセン化合物、これを含有する神経精神障害を治療するための調剤学的組成物、およびこの化合物を製造するための方法および中間体
US6545037B2 (en) Benzenesulfonamide compounds
SE449100B (sv) N-((4-fenyl-1,2,3,6-tetrahydropyridin-1-yl)alkylen)azaspiroalkandioner, forfarande for deras framstellning och farmaceutisk komposition derav
JPH04308584A (ja) 新規ベンゾイソオキサゾールおよびベンゾイソチアゾール化合物、その製造法ならびに医薬品組成物
CS248020B2 (en) Production method of the (+)-enantiomere or (+-)-racemical 4a,9b-trans-hexahydro-1h-pyridoindole derivatives
US5137894A (en) 4-(4-Piperidinyl-thieno[3,2-c]pyridine derivatives of n-alkylglutarimides
US3154557A (en) 2[omega-(2- and 4-pyridyl)-lower-alkoxy]tetrahydropyrans and compounds prepared therefrom
SE461040B (sv) Substituerade 3,4-diamino-1,2,5-tiadiazoler samt foerfarande foer framstaellning daerav
EP0552379B1 (fr) Derives de dihydropyridine et procede pour leur preparation
US3838118A (en) ((thioxanthenyl)propyl)-piperidyl-benzimidazolinones
DE2643671A1 (de) 4-phenylpiperidinyl- und 4 phenyltetrahydropyridinyl-alkylamino-ketoalkancarbonsaeuren und ihre salze mit saeuren und basen
AU733034B2 (en) Pyrazolopyridine compound and pharmaceutical use thereof
IE863015L (en) Heterocyclic compounds
WO2009109519A1 (fr) Nouveaux dérivés de la 4-benzhydryloxy-tetraalkyl-piperidine et leur utilisation en tant qu'inhibiteurs de la recapture des neurotransmetteurs monoamines
SE193202C1 (fr)

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 8201630-4

Effective date: 19941010

Format of ref document f/p: F