FR2501689B1 - N-((4-phenyl-1,2,3,6-tetrahydropyridine-1-yl)alkylene)azaspiroalcanediones, composition pharmaceutique les contenant, et n-((4-hydroxy-4-phenylpiperidine-1-yl)alkylene) azaspiroalcanediones intermediaires permettant de les obtenir - Google Patents

N-((4-phenyl-1,2,3,6-tetrahydropyridine-1-yl)alkylene)azaspiroalcanediones, composition pharmaceutique les contenant, et n-((4-hydroxy-4-phenylpiperidine-1-yl)alkylene) azaspiroalcanediones intermediaires permettant de les obtenir

Info

Publication number
FR2501689B1
FR2501689B1 FR8204101A FR8204101A FR2501689B1 FR 2501689 B1 FR2501689 B1 FR 2501689B1 FR 8204101 A FR8204101 A FR 8204101A FR 8204101 A FR8204101 A FR 8204101A FR 2501689 B1 FR2501689 B1 FR 2501689B1
Authority
FR
France
Prior art keywords
azaspiroalcanediones
alkylene
phenylpiperidine
tetrahydropyridine
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8204101A
Other languages
English (en)
Other versions
FR2501689A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FR2501689A1 publication Critical patent/FR2501689A1/fr
Application granted granted Critical
Publication of FR2501689B1 publication Critical patent/FR2501689B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
FR8204101A 1981-03-16 1982-03-11 N-((4-phenyl-1,2,3,6-tetrahydropyridine-1-yl)alkylene)azaspiroalcanediones, composition pharmaceutique les contenant, et n-((4-hydroxy-4-phenylpiperidine-1-yl)alkylene) azaspiroalcanediones intermediaires permettant de les obtenir Expired FR2501689B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/244,426 US4320131A (en) 1981-03-16 1981-03-16 N-[(4-Phenyl-1,2,3,6-tetrahydropyridin-1-yl)alkylene]azaspiroalkanediones and N-[(4-hydroxy-4-phenylpiperidin-1-yl)alkylene]azaspiroalkanediones

Publications (2)

Publication Number Publication Date
FR2501689A1 FR2501689A1 (fr) 1982-09-17
FR2501689B1 true FR2501689B1 (fr) 1985-07-19

Family

ID=22922718

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8204101A Expired FR2501689B1 (fr) 1981-03-16 1982-03-11 N-((4-phenyl-1,2,3,6-tetrahydropyridine-1-yl)alkylene)azaspiroalcanediones, composition pharmaceutique les contenant, et n-((4-hydroxy-4-phenylpiperidine-1-yl)alkylene) azaspiroalcanediones intermediaires permettant de les obtenir

Country Status (31)

Country Link
US (1) US4320131A (fr)
JP (1) JPS57165384A (fr)
KR (1) KR880001557B1 (fr)
AT (1) AT381939B (fr)
AU (1) AU535385B2 (fr)
BE (1) BE892502A (fr)
CA (1) CA1192556A (fr)
CH (2) CH652123A5 (fr)
CY (1) CY1372A (fr)
DE (1) DE3209534A1 (fr)
DK (1) DK161322C (fr)
ES (1) ES8305753A1 (fr)
FI (1) FI71317C (fr)
FR (1) FR2501689B1 (fr)
GB (1) GB2094801B (fr)
GR (1) GR76113B (fr)
HK (1) HK4688A (fr)
HU (2) HU193379B (fr)
IE (1) IE52789B1 (fr)
IL (1) IL65254A0 (fr)
IT (1) IT1148145B (fr)
KE (1) KE3710A (fr)
LU (1) LU84012A1 (fr)
NL (1) NL8201022A (fr)
NZ (1) NZ199944A (fr)
PH (1) PH18182A (fr)
PT (1) PT74584B (fr)
SE (2) SE449100B (fr)
SG (1) SG30887G (fr)
YU (1) YU43789B (fr)
ZA (1) ZA821541B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2660407B2 (ja) * 1986-09-26 1997-10-08 住友製薬株式会社 新規なイミド誘導体
HU207310B (en) * 1988-12-02 1993-03-29 Pfizer Process for producing aryl-piperidine derivatives
US5137894A (en) * 1991-12-05 1992-08-11 New James S 4-(4-Piperidinyl-thieno[3,2-c]pyridine derivatives of n-alkylglutarimides

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US355877A (en) * 1887-01-11 Waltee n
FR3013E (fr) * 1902-04-03 1904-08-12 William Henry Hoyle Perfectionnements au procédé et aux machines pour la fabrication de matières fibreuses connues sous le nom de fils "frottés"
US3106552A (en) * 1960-07-19 1963-10-08 Geschickter Fund Med Res Nu-substituted azaspiranes and azaspirane-diones and processes for their preparation
US3432499A (en) * 1965-04-02 1969-03-11 Geschickter Fund Med Res Trifluoromethylazaspiranes and azaspirane diones
US3398151A (en) * 1966-02-01 1968-08-20 Mead Johnson & Co Azaspirodecanediones and azaspiroundecanediones
US3558777A (en) * 1968-06-21 1971-01-26 Mead Johnson & Co Pharmacologic processes and compositions containing azaspirodecanediones and azaspiroundecanediones
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
CH547802A (de) * 1970-06-19 1974-04-11 Hoffmann La Roche Verfahren zur herstellung von tetrahydropyridinderivaten.
US3976776A (en) * 1972-12-06 1976-08-24 Mead Johnson & Company Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones
US4250175A (en) * 1977-10-31 1981-02-10 Mccall John M Methods of treating psychosis
US4179510A (en) * 1977-10-31 1979-12-18 The Upjohn Company Methods of treating psychosis
US4218456A (en) * 1978-07-10 1980-08-19 Warner-Lambert Company 1-(4-Fluorophenyl)-4-(1,2,3,6-tetrahydro-4-phenoxy-1-pyridinyl)-butanones
US4261990A (en) * 1979-03-09 1981-04-14 Ciba-Geigy Corporation N-alkyleneiminoalkyl-dicarboximides as antiallergics and antiasthmatics
US4221714A (en) * 1979-08-03 1980-09-09 American Cyanamid Company 11-(1,2,3,6-Tetrahydro-substituted-4-pyridyl)-dibenz[b,f][1,4]oxazepines
US4305944A (en) * 1980-09-08 1981-12-15 Mead Johnson & Company N-[(4-[3-cyano substituted pyridyl]piperazino)alkyl]-azaspirodecanediones

Also Published As

Publication number Publication date
CA1192556A (fr) 1985-08-27
DK161322C (da) 1991-12-09
IL65254A0 (en) 1982-05-31
LU84012A1 (fr) 1983-02-22
PH18182A (en) 1985-04-12
PT74584A (en) 1982-04-01
GB2094801B (en) 1985-04-24
ES510448A0 (es) 1983-04-16
US4320131A (en) 1982-03-16
CH652123A5 (de) 1985-10-31
AT381939B (de) 1986-12-10
HU190793B (en) 1986-11-28
NL8201022A (nl) 1982-10-18
KR830008680A (ko) 1983-12-14
FI820855L (fi) 1982-09-17
KR880001557B1 (ko) 1988-08-22
DE3209534A1 (de) 1982-09-23
PT74584B (pt) 1984-11-27
IE820590L (en) 1982-09-16
CY1372A (en) 1987-08-07
HK4688A (en) 1988-01-29
SE8201630L (sv) 1982-09-17
YU55882A (en) 1984-10-31
FI71317B (fi) 1986-09-09
GB2094801A (en) 1982-09-22
CH657365A5 (de) 1986-08-29
SE460606B (sv) 1989-10-30
IE52789B1 (en) 1988-03-02
SG30887G (en) 1987-07-17
AU8133582A (en) 1982-11-04
HU193379B (en) 1987-09-28
YU43789B (en) 1989-12-31
JPH0345072B2 (fr) 1991-07-09
DK112682A (da) 1982-09-17
ES8305753A1 (es) 1983-04-16
HUT40797A (en) 1987-02-27
NZ199944A (en) 1986-06-11
BE892502A (fr) 1982-09-15
AU535385B2 (en) 1984-03-15
IT1148145B (it) 1986-11-26
DE3209534C2 (fr) 1993-03-11
SE449100B (sv) 1987-04-06
FR2501689A1 (fr) 1982-09-17
SE8603177D0 (sv) 1986-07-21
ZA821541B (en) 1983-01-26
ATA104682A (de) 1986-05-15
JPS57165384A (en) 1982-10-12
IT8247992A0 (it) 1982-03-15
KE3710A (en) 1987-04-16
FI71317C (fi) 1986-12-19
GR76113B (fr) 1984-08-03
SE8603177L (sv) 1986-07-21
DK161322B (da) 1991-06-24

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ST Notification of lapse