SE422211B - Analogiforfarande for framstellning av 2-acyl-4-pyrazino(2,1-a)isokinolin-derivat - Google Patents
Analogiforfarande for framstellning av 2-acyl-4-pyrazino(2,1-a)isokinolin-derivatInfo
- Publication number
- SE422211B SE422211B SE7415686A SE7415686A SE422211B SE 422211 B SE422211 B SE 422211B SE 7415686 A SE7415686 A SE 7415686A SE 7415686 A SE7415686 A SE 7415686A SE 422211 B SE422211 B SE 422211B
- Authority
- SE
- Sweden
- Prior art keywords
- isoqinoline
- pyrazino
- acyl
- derivatives
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Fodder In General (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2362539A DE2362539C2 (de) | 1973-12-17 | 1973-12-17 | 2-Acyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isochinoline, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7415686L SE7415686L (sv) | 1975-06-18 |
| SE422211B true SE422211B (sv) | 1982-02-22 |
Family
ID=5900929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7415686A SE422211B (sv) | 1973-12-17 | 1974-12-13 | Analogiforfarande for framstellning av 2-acyl-4-pyrazino(2,1-a)isokinolin-derivat |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US4001411A (sv) |
| JP (1) | JPS5826352B2 (sv) |
| AR (2) | AR208527A1 (sv) |
| AT (1) | AT346334B (sv) |
| BE (1) | BE823400A (sv) |
| CA (1) | CA1036606A (sv) |
| CH (3) | CH612195A5 (sv) |
| CS (1) | CS241002B2 (sv) |
| DD (1) | DD115908A5 (sv) |
| DE (1) | DE2362539C2 (sv) |
| DK (1) | DK141845C (sv) |
| ES (2) | ES432974A1 (sv) |
| FI (1) | FI59594C (sv) |
| FR (1) | FR2254343B1 (sv) |
| GB (1) | GB1441554A (sv) |
| GR (1) | GR60708B (sv) |
| GT (1) | GT197850798A (sv) |
| HK (1) | HK13379A (sv) |
| HU (1) | HU170858B (sv) |
| IE (1) | IE40124B1 (sv) |
| IL (1) | IL46162A (sv) |
| IN (1) | IN139511B (sv) |
| IT (1) | IT7851978A0 (sv) |
| KE (1) | KE2946A (sv) |
| LU (1) | LU71204A1 (sv) |
| NL (1) | NL185406C (sv) |
| NO (1) | NO142304C (sv) |
| OA (1) | OA04868A (sv) |
| PH (1) | PH14220A (sv) |
| PL (3) | PL99105B1 (sv) |
| RO (1) | RO66907A (sv) |
| SE (1) | SE422211B (sv) |
| SU (3) | SU631070A3 (sv) |
| YU (1) | YU41288B (sv) |
| ZA (1) | ZA747253B (sv) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4196291A (en) * | 1973-12-17 | 1980-04-01 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | 2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof |
| US4113867A (en) * | 1973-12-17 | 1978-09-12 | Merck Patent Gesellschaft Mit Beschrankter Haftung | 2-acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof |
| US4162319A (en) * | 1974-08-28 | 1979-07-24 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Ring substituted pyrazino-isoquinoline derivatives and their preparation |
| US4120961A (en) * | 1974-08-28 | 1978-10-17 | E. Merck | Ring substituted pyrazino-isoquinoline derivatives and their preparation |
| DE2441261A1 (de) * | 1974-08-28 | 1976-03-18 | Merck Patent Gmbh | Ringsubstituierte pyrazino-isochinolin-derivat und verfahren zu ihrer herstellung |
| DE2841668A1 (de) * | 1978-09-25 | 1980-04-10 | Bayer Ag | Medikiertes tierfutter auf basis lebermehl |
| US4303659A (en) * | 1979-08-22 | 1981-12-01 | Pfizer Inc. | Schistosomicidal compositions |
| FR2520740A1 (fr) * | 1982-01-29 | 1983-08-05 | Sanofi Sa | Procede pour la preparation d'acyl-2-hexahydro-1,3,4,6,7,11b-2h-pyrazino (2,1-a) isoquinoleinones-4 et intermediaires |
| DE3472678D1 (de) * | 1983-07-18 | 1988-08-18 | Beecham Group Plc | Benzazepine and benzoxazepine derivatives |
| DE3634755A1 (de) * | 1986-10-11 | 1988-04-14 | Bayer Ag | Dermale behandlung von wurmerkrankungen der katze mit praziquantel |
| NZ247278A (en) * | 1991-02-12 | 1995-03-28 | Ancare Distributors | Veterinary anthelmintic drench comprising a suspension of praziquantel in a liquid carrier |
| DE19628776A1 (de) | 1996-07-17 | 1998-01-22 | Bayer Ag | Oral applizierbare Granulate von Hexahydropyrazinderivaten |
| US6429211B1 (en) | 2000-05-23 | 2002-08-06 | Bayer Corporation | Praziquantel compounds for treating diseases due to Sarcocystis Neospora Toxoplasma and Isospora |
| US7396819B2 (en) | 2003-08-08 | 2008-07-08 | Virbac Corporation | Anthelmintic formulations |
| DE10358525A1 (de) * | 2003-12-13 | 2005-07-07 | Bayer Healthcare Ag | Endoparasitizide Mittel zur topischen Applikation |
| RU2266906C1 (ru) * | 2004-04-29 | 2005-12-27 | Общество с ограниченной ответственностью "Исследовательский Институт Химического Разнообразия" (ООО "Исследовательский Институт Химического Разнообразия") | Анелированные карбамоилазагетероциклы, способы их получения (варианты), фармацевтическая композиция, фокусированная библиотека |
| DE102004055316A1 (de) * | 2004-11-16 | 2006-05-18 | Bayer Healthcare Ag | Verhinderung vertikaler Endoparasiten-Infektionen |
| KR100682506B1 (ko) * | 2005-01-18 | 2007-02-15 | (주)젠크로스 | 프라지콴텔, 또는 이의 염을 포함하는 약학 조성물 |
| DE102005011779A1 (de) * | 2005-03-11 | 2006-09-14 | Bayer Healthcare Ag | Endoparasitizide Mittel |
| EP1890547A2 (en) * | 2005-06-09 | 2008-02-27 | Schering-Plough Ltd. | Control of parasites in animals by n-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and n-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives |
| FR2912145B1 (fr) * | 2007-02-02 | 2009-03-06 | Servier Lab | Nouveaux derives tricycliques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| ITPD20070274A1 (it) * | 2007-08-08 | 2009-02-09 | Sanypet S P A | Crocchetta per animali e metodo per la sua produzione |
| ES2748136T3 (es) | 2007-10-15 | 2020-03-13 | United Animal Health Inc | Método para aumentar el rendimiento de las crías |
| DE102008022520A1 (de) * | 2008-05-07 | 2009-11-12 | Bayer Animal Health Gmbh | Feste Arzneimittelformulierung mit verzögerter Freisetzung |
| AP2909A (en) | 2009-03-17 | 2014-05-31 | Concert Pharmaceuticals Inc | Pyrazinoisoquinoline Compounds |
| CN102093346B (zh) * | 2010-03-16 | 2012-09-05 | 浙江金伯士药业有限公司 | 一种吡喹酮的制备方法 |
| WO2012122028A2 (en) | 2011-03-04 | 2012-09-13 | Concert Pharmaceuticals Inc. | Pyrazinoisoquinoline compounds |
| CN103910725B (zh) * | 2013-01-09 | 2015-12-02 | 江南大学 | 一类吡喹酮类似物、其制备方法和用途 |
-
1973
- 1973-12-17 DE DE2362539A patent/DE2362539C2/de not_active Expired
-
1974
- 1974-10-29 LU LU71204A patent/LU71204A1/xx unknown
- 1974-11-12 ZA ZA00747253A patent/ZA747253B/xx unknown
- 1974-11-12 GB GB4886174A patent/GB1441554A/en not_active Expired
- 1974-11-18 IE IE2373/74A patent/IE40124B1/xx unknown
- 1974-11-22 IN IN2601/CAL/74A patent/IN139511B/en unknown
- 1974-11-29 IL IL46162A patent/IL46162A/xx unknown
- 1974-12-11 CS CS748427A patent/CS241002B2/cs unknown
- 1974-12-12 PH PH16619A patent/PH14220A/en unknown
- 1974-12-13 AT AT996274A patent/AT346334B/de not_active IP Right Cessation
- 1974-12-13 AR AR256891A patent/AR208527A1/es active
- 1974-12-13 RO RO7480781A patent/RO66907A/ro unknown
- 1974-12-13 SE SE7415686A patent/SE422211B/sv not_active IP Right Cessation
- 1974-12-16 DD DD183078A patent/DD115908A5/xx unknown
- 1974-12-16 FR FR7441356A patent/FR2254343B1/fr not_active Expired
- 1974-12-16 BE BE151546A patent/BE823400A/xx not_active IP Right Cessation
- 1974-12-16 PL PL1974187325A patent/PL99105B1/pl unknown
- 1974-12-16 PL PL1974187324A patent/PL99088B1/pl unknown
- 1974-12-16 HU HU74ME00001815A patent/HU170858B/hu unknown
- 1974-12-16 US US05/533,467 patent/US4001411A/en not_active Expired - Lifetime
- 1974-12-16 ES ES432974A patent/ES432974A1/es not_active Expired
- 1974-12-16 DK DK654274A patent/DK141845C/da not_active IP Right Cessation
- 1974-12-16 PL PL1974176506A patent/PL94074B1/pl unknown
- 1974-12-16 NO NO744521A patent/NO142304C/no unknown
- 1974-12-16 CA CA216,069A patent/CA1036606A/en not_active Expired
- 1974-12-16 FI FI3632/74A patent/FI59594C/fi active
- 1974-12-17 JP JP49145536A patent/JPS5826352B2/ja not_active Expired
- 1974-12-17 CH CH1675474A patent/CH612195A5/xx not_active IP Right Cessation
- 1974-12-17 YU YU3361/74A patent/YU41288B/xx unknown
- 1974-12-17 NL NLAANVRAGE7416432,A patent/NL185406C/xx not_active IP Right Cessation
- 1974-12-17 SU SU742084647A patent/SU631070A3/ru active
- 1974-12-17 GR GR5764A patent/GR60708B/el unknown
- 1974-12-17 OA OA55366A patent/OA04868A/xx unknown
-
1975
- 1975-09-26 AR AR260558A patent/AR208715A1/es active
- 1975-10-07 ES ES441546A patent/ES441546A1/es not_active Expired
-
1976
- 1976-11-25 SU SU762423403A patent/SU668603A3/ru active
- 1976-11-29 SU SU762423402A patent/SU625613A3/ru active
-
1978
- 1978-02-07 GT GT197850798A patent/GT197850798A/es unknown
- 1978-11-09 CH CH1154378A patent/CH620442A5/de not_active IP Right Cessation
- 1978-11-09 CH CH1154278A patent/CH621788A5/de not_active IP Right Cessation
- 1978-11-20 IT IT7851978A patent/IT7851978A0/it unknown
-
1979
- 1979-03-15 HK HK133/79A patent/HK13379A/xx unknown
- 1979-04-02 KE KE2946A patent/KE2946A/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
Ref document number: 7415686-0 Effective date: 19950110 Format of ref document f/p: F |
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| NUG | Patent has lapsed |
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