IT7851978A0 - Derivati di 2-acil-4-osso-pirazinoisochinolina e procedimento per laloro produzione - Google Patents

Derivati di 2-acil-4-osso-pirazinoisochinolina e procedimento per laloro produzione

Info

Publication number
IT7851978A0
IT7851978A0 IT7851978A IT5197878A IT7851978A0 IT 7851978 A0 IT7851978 A0 IT 7851978A0 IT 7851978 A IT7851978 A IT 7851978A IT 5197878 A IT5197878 A IT 5197878A IT 7851978 A0 IT7851978 A0 IT 7851978A0
Authority
IT
Italy
Prior art keywords
acil
oxo
procedure
production
pyrazinoisoquinoline
Prior art date
Application number
IT7851978A
Other languages
English (en)
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=5900929&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT7851978(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of IT7851978A0 publication Critical patent/IT7851978A0/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Fodder In General (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT7851978A 1973-12-17 1978-11-20 Derivati di 2-acil-4-osso-pirazinoisochinolina e procedimento per laloro produzione IT7851978A0 (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2362539A DE2362539C2 (de) 1973-12-17 1973-12-17 2-Acyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isochinoline, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
IT7851978A0 true IT7851978A0 (it) 1978-11-20

Family

ID=5900929

Family Applications (1)

Application Number Title Priority Date Filing Date
IT7851978A IT7851978A0 (it) 1973-12-17 1978-11-20 Derivati di 2-acil-4-osso-pirazinoisochinolina e procedimento per laloro produzione

Country Status (35)

Country Link
US (1) US4001411A (it)
JP (1) JPS5826352B2 (it)
AR (2) AR208527A1 (it)
AT (1) AT346334B (it)
BE (1) BE823400A (it)
CA (1) CA1036606A (it)
CH (3) CH612195A5 (it)
CS (1) CS241002B2 (it)
DD (1) DD115908A5 (it)
DE (1) DE2362539C2 (it)
DK (1) DK141845C (it)
ES (2) ES432974A1 (it)
FI (1) FI59594C (it)
FR (1) FR2254343B1 (it)
GB (1) GB1441554A (it)
GR (1) GR60708B (it)
GT (1) GT197850798A (it)
HK (1) HK13379A (it)
HU (1) HU170858B (it)
IE (1) IE40124B1 (it)
IL (1) IL46162A (it)
IN (1) IN139511B (it)
IT (1) IT7851978A0 (it)
KE (1) KE2946A (it)
LU (1) LU71204A1 (it)
NL (1) NL185406C (it)
NO (1) NO142304C (it)
OA (1) OA04868A (it)
PH (1) PH14220A (it)
PL (3) PL99105B1 (it)
RO (1) RO66907A (it)
SE (1) SE422211B (it)
SU (3) SU631070A3 (it)
YU (1) YU41288B (it)
ZA (1) ZA747253B (it)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196291A (en) * 1973-12-17 1980-04-01 Merck Patent Gesellschaft Mit Beschraenkter Haftung 2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof
US4113867A (en) * 1973-12-17 1978-09-12 Merck Patent Gesellschaft Mit Beschrankter Haftung 2-acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof
US4162319A (en) * 1974-08-28 1979-07-24 Merck Patent Gesellschaft Mit Beschrankter Haftung Ring substituted pyrazino-isoquinoline derivatives and their preparation
US4120961A (en) * 1974-08-28 1978-10-17 E. Merck Ring substituted pyrazino-isoquinoline derivatives and their preparation
DE2441261A1 (de) * 1974-08-28 1976-03-18 Merck Patent Gmbh Ringsubstituierte pyrazino-isochinolin-derivat und verfahren zu ihrer herstellung
DE2841668A1 (de) * 1978-09-25 1980-04-10 Bayer Ag Medikiertes tierfutter auf basis lebermehl
US4303659A (en) * 1979-08-22 1981-12-01 Pfizer Inc. Schistosomicidal compositions
FR2520740A1 (fr) * 1982-01-29 1983-08-05 Sanofi Sa Procede pour la preparation d'acyl-2-hexahydro-1,3,4,6,7,11b-2h-pyrazino (2,1-a) isoquinoleinones-4 et intermediaires
DE3472678D1 (de) * 1983-07-18 1988-08-18 Beecham Group Plc Benzazepine and benzoxazepine derivatives
DE3634755A1 (de) * 1986-10-11 1988-04-14 Bayer Ag Dermale behandlung von wurmerkrankungen der katze mit praziquantel
NZ247278A (en) * 1991-02-12 1995-03-28 Ancare Distributors Veterinary anthelmintic drench comprising a suspension of praziquantel in a liquid carrier
DE19628776A1 (de) 1996-07-17 1998-01-22 Bayer Ag Oral applizierbare Granulate von Hexahydropyrazinderivaten
US6429211B1 (en) 2000-05-23 2002-08-06 Bayer Corporation Praziquantel compounds for treating diseases due to Sarcocystis Neospora Toxoplasma and Isospora
US7396819B2 (en) 2003-08-08 2008-07-08 Virbac Corporation Anthelmintic formulations
DE10358525A1 (de) * 2003-12-13 2005-07-07 Bayer Healthcare Ag Endoparasitizide Mittel zur topischen Applikation
RU2266906C1 (ru) * 2004-04-29 2005-12-27 Общество с ограниченной ответственностью "Исследовательский Институт Химического Разнообразия" (ООО "Исследовательский Институт Химического Разнообразия") Анелированные карбамоилазагетероциклы, способы их получения (варианты), фармацевтическая композиция, фокусированная библиотека
DE102004055316A1 (de) * 2004-11-16 2006-05-18 Bayer Healthcare Ag Verhinderung vertikaler Endoparasiten-Infektionen
KR100682506B1 (ko) * 2005-01-18 2007-02-15 (주)젠크로스 프라지콴텔, 또는 이의 염을 포함하는 약학 조성물
DE102005011779A1 (de) * 2005-03-11 2006-09-14 Bayer Healthcare Ag Endoparasitizide Mittel
EP1890547A2 (en) * 2005-06-09 2008-02-27 Schering-Plough Ltd. Control of parasites in animals by n-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and n-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives
FR2912145B1 (fr) * 2007-02-02 2009-03-06 Servier Lab Nouveaux derives tricycliques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent
ITPD20070274A1 (it) * 2007-08-08 2009-02-09 Sanypet S P A Crocchetta per animali e metodo per la sua produzione
ES2748136T3 (es) 2007-10-15 2020-03-13 United Animal Health Inc Método para aumentar el rendimiento de las crías
DE102008022520A1 (de) * 2008-05-07 2009-11-12 Bayer Animal Health Gmbh Feste Arzneimittelformulierung mit verzögerter Freisetzung
AP2909A (en) 2009-03-17 2014-05-31 Concert Pharmaceuticals Inc Pyrazinoisoquinoline Compounds
CN102093346B (zh) * 2010-03-16 2012-09-05 浙江金伯士药业有限公司 一种吡喹酮的制备方法
WO2012122028A2 (en) 2011-03-04 2012-09-13 Concert Pharmaceuticals Inc. Pyrazinoisoquinoline compounds
CN103910725B (zh) * 2013-01-09 2015-12-02 江南大学 一类吡喹酮类似物、其制备方法和用途

Also Published As

Publication number Publication date
SE422211B (sv) 1982-02-22
CH612195A5 (it) 1979-07-13
NL185406C (nl) 1990-04-02
DD115908A5 (it) 1975-10-20
AR208715A1 (es) 1977-02-28
AR208527A1 (es) 1977-02-15
US4001411A (en) 1977-01-04
DK654274A (it) 1975-08-25
SE7415686L (it) 1975-06-18
RO66907A (ro) 1981-06-26
PL94074B1 (it) 1977-07-30
PL99088B1 (pl) 1978-06-30
IL46162A0 (en) 1975-02-10
IN139511B (it) 1976-06-26
DK141845C (da) 1980-12-22
LU71204A1 (it) 1975-04-17
DE2362539A1 (de) 1975-08-28
IE40124L (en) 1975-06-17
BE823400A (fr) 1975-06-16
HK13379A (en) 1979-03-23
HU170858B (hu) 1977-09-28
JPS5826352B2 (ja) 1983-06-02
FI59594C (fi) 1981-09-10
AU7643874A (en) 1976-06-17
CA1036606A (en) 1978-08-15
DK141845B (da) 1980-06-30
NO142304C (no) 1980-07-30
NL185406B (nl) 1989-11-01
YU41288B (en) 1987-02-28
OA04868A (fr) 1980-10-31
ES441546A1 (es) 1977-04-16
JPS5093999A (it) 1975-07-26
CS241002B2 (en) 1986-03-13
FR2254343B1 (it) 1978-06-30
NL7416432A (nl) 1975-06-19
ZA747253B (en) 1975-11-26
GR60708B (en) 1978-07-24
PL99105B1 (pl) 1978-06-30
CS842774A2 (en) 1985-06-13
CH620442A5 (it) 1980-11-28
CH621788A5 (it) 1981-02-27
DE2362539C2 (de) 1986-05-07
IE40124B1 (en) 1979-03-14
YU336174A (en) 1983-01-21
ES432974A1 (es) 1977-02-16
FR2254343A1 (it) 1975-07-11
AT346334B (de) 1978-11-10
FI59594B (fi) 1981-05-29
GB1441554A (en) 1976-07-07
SU625613A3 (ru) 1978-09-25
PH14220A (en) 1981-04-02
KE2946A (en) 1979-04-12
IL46162A (en) 1979-01-31
GT197850798A (es) 1979-08-01
NO142304B (no) 1980-04-21
ATA996274A (de) 1978-03-15
SU631070A3 (ru) 1978-10-30
NO744521L (it) 1975-07-14
FI363274A (it) 1975-06-18
SU668603A3 (ru) 1979-06-15

Similar Documents

Publication Publication Date Title
IT7851978A0 (it) Derivati di 2-acil-4-osso-pirazinoisochinolina e procedimento per laloro produzione
RO73008A (ro) Procedeu pentru prepararea unor derivati de difenileter-4-trifluormetil-4-nitro halogenati
IT989253B (it) Derivati di acrilonitrili
IT1053772B (it) Derivati n aminosolfenilati di carbofurano
IT1049283B (it) Derivati ossazolidinici
IT1007598B (it) Piperidin derivati
IT961240B (it) Procedimento per la produzione di difenilammina e suoi derivati
RO71309A (ro) Procedeu pentru prepararea unor derivati de benzo-sulfonil-uree
IT974374B (it) Procedimento per la produzione di dicloro i i diantrachinonili e loro derivati
IT1028065B (it) Derivati fenolici di immidi policioliche
RO87769A (ro) Procedeu pentru prepararea unor derivati de tiazolidina
IT988441B (it) Procedimento per la produzione di polisaccaride
IT1049274B (it) Derivati di dinitroanilina
RO69154A (ro) Procedeu pentru prepararea unor derivati de 1-fenoxi-3-aminopropan-2-ol
RO66743A (ro) Procedeu pentru prepararea unor derivati ai lactamelor
IT1051355B (it) Procedimento per preparare polialoe miacetal derivati di polisaccaridi
IT1048503B (it) Derivati nitrobenzenici
BE812655A (fr) Derives imidazo-heterocycliques
IT1047936B (it) Derivati di ossimminofosforotilolato e procedimento per la loro produzione ed applicazione
RO70259A (ro) Procedeu pentru prepararea unor derivati ai propanolului
RO70190A (ro) Procedeu pentru prepararea unor derivati de netroimidazol
RO63766A (ro) Procedeu pentru prepararea unor derivati ai 1-fenoxi-3-aminopropan-2-olului
IT7948382A0 (it) Derivati di pirazinoindolo e procedimenti per la loro produzione
IT1002391B (it) Procedimento per la preparazione di tricicloesilstagno derivati
IT978791B (it) Processo per la preparazione di carbonil derivati