SE393376B - Forfarande for framstellning av pyrimidinonderivat - Google Patents

Forfarande for framstellning av pyrimidinonderivat

Info

Publication number
SE393376B
SE393376B SE7212358A SE1235872A SE393376B SE 393376 B SE393376 B SE 393376B SE 7212358 A SE7212358 A SE 7212358A SE 1235872 A SE1235872 A SE 1235872A SE 393376 B SE393376 B SE 393376B
Authority
SE
Sweden
Prior art keywords
pyrimidinon
derivatives
preparing
procedure
pyrimidinon derivatives
Prior art date
Application number
SE7212358A
Other languages
English (en)
Swedish (sv)
Inventor
C A Lipinski
J G Stam
G G Deangelis
H-J E Hess
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of SE393376B publication Critical patent/SE393376B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56One oxygen atom and one sulfur atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60Three or more oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SE7212358A 1971-10-29 1972-09-25 Forfarande for framstellning av pyrimidinonderivat SE393376B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19400671A 1971-10-29 1971-10-29

Publications (1)

Publication Number Publication Date
SE393376B true SE393376B (sv) 1977-05-09

Family

ID=22715935

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7212358A SE393376B (sv) 1971-10-29 1972-09-25 Forfarande for framstellning av pyrimidinonderivat
SE7505279A SE397090B (sv) 1971-10-29 1975-05-06 Forfarande for framstellning av hydroxipyrimidiner

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE7505279A SE397090B (sv) 1971-10-29 1975-05-06 Forfarande for framstellning av hydroxipyrimidiner

Country Status (25)

Country Link
JP (2) JPS5337870B2 (fi)
AR (2) AR198798A1 (fi)
AT (2) AT320656B (fi)
AU (1) AU467600B2 (fi)
BE (1) BE790125A (fi)
CA (1) CA980778A (fi)
CH (2) CH555832A (fi)
DE (3) DE2264374C3 (fi)
DK (1) DK131465B (fi)
EG (1) EG11013A (fi)
ES (2) ES407730A1 (fi)
FI (1) FI55503C (fi)
FR (1) FR2157865B1 (fi)
GB (2) GB1377720A (fi)
IE (1) IE37043B1 (fi)
IL (2) IL40458A (fi)
LU (1) LU66304A1 (fi)
NL (1) NL166470C (fi)
NO (1) NO136574C (fi)
PH (2) PH10129A (fi)
PL (2) PL84634B1 (fi)
SE (2) SE393376B (fi)
SU (2) SU498908A3 (fi)
YU (2) YU35125B (fi)
ZA (1) ZA727362B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55151912U (fi) * 1979-04-17 1980-11-01
JPS5752409Y2 (fi) * 1979-11-05 1982-11-15
DE3222914A1 (de) * 1982-06-18 1983-12-22 Beiersdorf Ag, 2000 Hamburg Substituierte 5-phenylthio-6-amino-pyrimidinone, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
JPH0655686B2 (ja) * 1988-08-30 1994-07-27 宇部興産株式会社 p−ブロモフェノキシアセトアルデヒドジアルキルアセタール類の製造方法
CA2620065C (en) 2005-08-22 2011-03-29 Melior Discovery, Inc. Methods and formulations for modulating lyn kinase activity and treating related disorders
US8552184B2 (en) 2008-07-03 2013-10-08 Melior Pharmaceuticals I, Inc. Compounds and methods for treating disorders related to glucose metabolism
WO2011150300A1 (en) 2010-05-28 2011-12-01 Melior Pharmaceuticals I, Inc. Prevention of pancreatic beta cell degeneration
SG11201909406VA (en) 2017-04-10 2019-11-28 Melior Pharmaceuticals I Inc Treatment of adipocytes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2913462A (en) * 1959-11-17 Eahl h
GB951431A (en) * 1959-03-17 1964-03-04 Wellcome Found Pyrimidine derivatives and the manufacture thereof

Also Published As

Publication number Publication date
DE2264657A1 (de) 1974-06-20
JPS4852780A (fi) 1973-07-24
ZA727362B (en) 1973-11-28
AU4722872A (en) 1974-04-04
DE2248741C3 (de) 1975-06-26
PH10129A (en) 1976-09-02
DK131465C (fi) 1975-12-08
YU99179A (en) 1981-08-31
JPS5422995B2 (fi) 1979-08-10
DK131465B (da) 1975-07-21
AR196263A1 (es) 1973-12-10
SU498908A3 (ru) 1976-01-05
NO136574B (fi) 1977-06-20
AU467600B2 (en) 1975-12-04
AT320656B (de) 1975-02-25
NL166470C (nl) 1981-08-17
IL40458A (en) 1976-05-31
CH555832A (fr) 1974-11-15
YU36295B (en) 1982-06-18
SE7505279L (sv) 1975-05-06
YU255172A (en) 1980-03-15
DE2264657C2 (de) 1982-09-16
IE37043L (en) 1973-04-29
EG11013A (en) 1976-11-30
FR2157865B1 (fi) 1975-10-31
SU505362A3 (ru) 1976-02-28
LU66304A1 (fi) 1973-05-03
JPS53116386A (en) 1978-10-11
GB1377720A (en) 1974-12-18
CH549579A (fr) 1974-05-31
AT321308B (de) 1975-03-25
ES407730A1 (es) 1976-01-16
PL84634B1 (fi) 1976-04-30
NL166470B (nl) 1981-03-16
BE790125A (fr) 1973-04-16
YU35125B (en) 1980-09-25
NL7213959A (fi) 1973-05-02
DE2248741A1 (de) 1973-05-03
JPS5337870B2 (fi) 1978-10-12
DE2264374C3 (de) 1981-07-23
CA980778A (en) 1975-12-30
ES436624A1 (es) 1977-02-01
FR2157865A1 (fi) 1973-06-08
AR198798A1 (es) 1974-07-24
PL89852B1 (fi) 1976-12-31
DE2248741B2 (de) 1974-11-14
IL48790A0 (en) 1976-03-31
NO136574C (no) 1977-09-28
PH11594A (en) 1978-03-31
FI55503B (fi) 1979-04-30
DE2264374A1 (de) 1973-05-24
IL48790A (en) 1976-05-31
GB1377308A (en) 1974-12-11
FI55503C (fi) 1979-08-10
IL40458A0 (en) 1972-11-28
SE397090B (sv) 1977-10-17
IE37043B1 (en) 1977-04-27
DE2264374B2 (de) 1980-08-07

Similar Documents

Publication Publication Date Title
SE422325B (sv) Forfarande for framstellning av vissa angivna 1,2,4-triazolderivat
SE432102B (sv) Forfarande for framstellning av estrar av penicilliner
SE398877B (sv) Forfarande for framstellning av 14-hydroxi-morfinanderivat
SE400771B (sv) Forfarande for framstellning av 3alfa-hydroxi- och 3alfa-hydroxi-19-norpregnaner
SE413246B (sv) Forfarande for framstellning av kolesteroloxidas
SE383358B (sv) Forfarande for framstellning av pullulan
SE399268B (sv) Forfarande for framstellning av nya purinnukleosidderivat
SE415978B (sv) Forfarande for framstellning av 7-acylamido-3-cefem-4-karbonsyror
SE419339B (sv) Forfarande for framstellning av substituerade sulfonylacetamidocefalosporiner
SE397530B (sv) Forfarande for framstellning av 1-pyrazolylalkyl-4-arylpiperazinderivat
NO139124C (no) Fremgangsmaate for fremstilling av estere
SE382809B (sv) Forfarande for framstellning av fenoxiettiksyraderivat
AR200387A1 (es) Procedimiento para preparar derivados de trifluorometilfenilpiperazina
SE423092B (sv) Forfarande for framstellning av vissa 13-tiaprostaglandiner
SE417711B (sv) Forfarande for framstellning av 5-iminometyl-2-nitroimidazolderivat
SE393376B (sv) Forfarande for framstellning av pyrimidinonderivat
SE395455B (sv) Forfarande for framstellning av 3-(fenyl-piperazinyl) etylindoliner
SE384686B (sv) Forfarande for framstellning av linkomycinderivat
SE387344B (sv) Forfarande for framstellning av pyrazin-4-oxidderivat
SE408177B (sv) Forfarande for framstellning av 4-hydroximetyl-1-ftalazonderivat
SE409858B (sv) Forfarande for framstallning av vissa angivna aminoalkylfenylacetonitrilderivat
SE373572B (sv) Forfarande for framstellning av pyroglutamyl-histidyl-prolinamid
SE402454B (sv) Forfarande for framstellning av 2-alkoxi-5-alkylsulfonyl-toluen
IT966747B (it) Procedimento per preparare dinitroantrachinoni
SE405119B (sv) Forfarande for framstellning av 2,4-diamino-5-bensyl-pyrimidiner