SE400771B - Forfarande for framstellning av 3alfa-hydroxi- och 3alfa-hydroxi-19-norpregnaner - Google Patents
Forfarande for framstellning av 3alfa-hydroxi- och 3alfa-hydroxi-19-norpregnanerInfo
- Publication number
- SE400771B SE400771B SE7306330A SE7306330A SE400771B SE 400771 B SE400771 B SE 400771B SE 7306330 A SE7306330 A SE 7306330A SE 7306330 A SE7306330 A SE 7306330A SE 400771 B SE400771 B SE 400771B
- Authority
- SE
- Sweden
- Prior art keywords
- 3alfa
- hydroxi
- norpregnaner
- preparing
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
- C07J5/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2114272A GB1430942A (en) | 1972-05-05 | 1972-05-05 | 21-substituted 3alpha-hydroxy pregnanes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE400771B true SE400771B (sv) | 1978-04-10 |
Family
ID=10157915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7306330A SE400771B (sv) | 1972-05-05 | 1973-05-04 | Forfarande for framstellning av 3alfa-hydroxi- och 3alfa-hydroxi-19-norpregnaner |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS4961150A (sv) |
| AT (1) | AT355232B (sv) |
| AU (1) | AU475168B2 (sv) |
| BE (1) | BE799102A (sv) |
| CA (1) | CA1013341A (sv) |
| CH (1) | CH617710A5 (sv) |
| DE (1) | DE2322532A1 (sv) |
| ES (1) | ES414411A1 (sv) |
| FR (1) | FR2183792B1 (sv) |
| GB (1) | GB1430942A (sv) |
| IE (1) | IE37596B1 (sv) |
| IL (1) | IL42196A (sv) |
| LU (1) | LU67546A1 (sv) |
| NL (1) | NL7306234A (sv) |
| SE (1) | SE400771B (sv) |
| ZA (1) | ZA733035B (sv) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5232917A (en) * | 1987-08-25 | 1993-08-03 | University Of Southern California | Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series |
| IL112638A (en) * | 1994-02-14 | 2003-10-31 | Cocensys Inc | 3alpha-HYDROXYLATED PREGNANE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME |
| US5939545A (en) * | 1994-02-14 | 1999-08-17 | Cocensys, Inc. | Method, compositions, and compounds for allosteric modulation of the gaba receptor by members of the androstane and pregnane series |
| GR1003861B (el) * | 2000-12-29 | 2002-04-11 | Νεα νευροστεροειδη που αλληλεπιδρουν με τον υποδοχεα gabaa. | |
| JP4915427B2 (ja) * | 2009-03-30 | 2012-04-11 | ブラザー工業株式会社 | 液体供給ジョイント、これを使用した液体吐出ヘッド及び記録装置 |
| CN108976272B (zh) | 2011-10-14 | 2021-05-25 | 萨奇治疗股份有限公司 | 3,3-二取代的19-去甲孕甾烷化合物、组合物、及其用途 |
| NZ627781A (en) | 2012-01-23 | 2016-10-28 | Sage Therapeutics Inc | Neuroactive steroid formulations and methods of treating cns disorders |
| IL275725B (en) | 2012-08-21 | 2022-08-01 | Sage Therapeutics Inc | Treatment methods for epilepsy and status epilepticus |
| US9725481B2 (en) | 2013-04-17 | 2017-08-08 | Sage Therapeutics, Inc. | 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof |
| ES2807264T3 (es) | 2013-04-17 | 2021-02-22 | Sage Therapeutics Inc | Esteroides neuroactivos 19-nor para métodos de tratamiento |
| HUE041369T2 (hu) | 2013-04-17 | 2019-05-28 | Sage Therapeutics Inc | 19-nor C3,3-diszubsztituált C21-N-pirazolil-szteroidok és eljárás ezek alkalmazására |
| US20160068563A1 (en) | 2013-04-17 | 2016-03-10 | Boyd L. Harrison | 19-nor neuroactive steroids and methods of use thereof |
| CA3199003A1 (en) | 2013-07-19 | 2015-01-22 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| CA3235088A1 (en) | 2013-08-23 | 2015-02-26 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| WO2015195962A1 (en) | 2014-06-18 | 2015-12-23 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| JOP20200195A1 (ar) | 2014-09-08 | 2017-06-16 | Sage Therapeutics Inc | سترويدات وتركيبات نشطة عصبياً، واستخداماتها |
| US20170233433A1 (en) | 2014-10-16 | 2017-08-17 | Sage Therapeutics, Inc. | Compositions and methods for treating cns disorders |
| MX2017005002A (es) | 2014-10-16 | 2018-01-23 | Sage Therapeutics Inc | Composiciones y metodos para el tratamiento de trastornos del snc. |
| EP3719029A1 (en) | 2014-11-27 | 2020-10-07 | Sage Therapeutics, Inc. | Compositions for inducing sedation |
| RS61530B1 (sr) | 2015-01-26 | 2021-04-29 | Sage Therapeutics Inc | Kompozicije i postupci za lečenje poremećaja cns |
| DK3258939T3 (da) | 2015-02-20 | 2022-12-12 | Sage Therapeutics Inc | Neuroaktive steroider, sammensætninger og anvendelser heraf |
| KR102408399B1 (ko) | 2016-03-08 | 2022-06-13 | 세이지 테라퓨틱스, 인크. | 신경활성 스테로이드, 조성물, 및 그의 용도 |
| JP7065825B2 (ja) | 2016-07-11 | 2022-05-12 | セージ セラピューティクス， インコーポレイテッド | Ｃ７、ｃ１２、およびｃ１６置換神経刺激性ステロイドおよびそれらの使用方法 |
| IL309259A (en) | 2016-07-11 | 2024-02-01 | Sage Therapeutics Inc | C17, C20 and C21 converted neuroactive steroids and methods of using them |
| MA56046A (fr) | 2019-05-31 | 2022-04-06 | Sage Therapeutics Inc | Stéroïdes neuroactifs et compositions associées |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1346292A (fr) * | 1962-09-14 | 1963-12-20 | Roussel Uclaf | Nouveau procédé de préparation des 21-amino stéroïdes |
| US3144446A (en) * | 1963-12-20 | 1964-08-11 | Upjohn Co | Mono and bis nu-(3alpha, 17alpha-dihydroxy-11, 20-dioxo-5beta-pregnan-21-yl) quaternary ammonium salts of triethylenediamine |
-
1972
- 1972-05-05 GB GB2114272A patent/GB1430942A/en not_active Expired
-
1973
- 1973-05-04 AT AT395173A patent/AT355232B/de not_active IP Right Cessation
- 1973-05-04 FR FR7316108A patent/FR2183792B1/fr not_active Expired
- 1973-05-04 DE DE2322532A patent/DE2322532A1/de not_active Ceased
- 1973-05-04 CH CH636073A patent/CH617710A5/de not_active IP Right Cessation
- 1973-05-04 BE BE130749A patent/BE799102A/xx unknown
- 1973-05-04 JP JP48050183A patent/JPS4961150A/ja active Pending
- 1973-05-04 CA CA170,482A patent/CA1013341A/en not_active Expired
- 1973-05-04 LU LU67546A patent/LU67546A1/xx unknown
- 1973-05-04 IL IL42196A patent/IL42196A/xx unknown
- 1973-05-04 SE SE7306330A patent/SE400771B/sv unknown
- 1973-05-04 AU AU55284/73A patent/AU475168B2/en not_active Expired
- 1973-05-04 ZA ZA733035A patent/ZA733035B/xx unknown
- 1973-05-04 NL NL7306234A patent/NL7306234A/xx not_active Application Discontinuation
- 1973-05-04 ES ES0414411A patent/ES414411A1/es not_active Expired
- 1973-05-04 IE IE709/73A patent/IE37596B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATA395173A (de) | 1979-07-15 |
| NL7306234A (sv) | 1973-11-07 |
| BE799102A (fr) | 1973-11-05 |
| AU475168B2 (en) | 1976-08-12 |
| FR2183792A1 (sv) | 1973-12-21 |
| CH617710A5 (en) | 1980-06-13 |
| AT355232B (de) | 1980-02-25 |
| IE37596L (en) | 1973-11-05 |
| IE37596B1 (en) | 1977-08-31 |
| ZA733035B (en) | 1974-04-24 |
| IL42196A (en) | 1978-10-31 |
| IL42196A0 (en) | 1973-07-30 |
| GB1430942A (en) | 1976-04-07 |
| LU67546A1 (sv) | 1973-07-13 |
| FR2183792B1 (sv) | 1977-07-15 |
| DE2322532A1 (de) | 1973-11-22 |
| ES414411A1 (es) | 1976-02-01 |
| AU5528473A (en) | 1974-11-07 |
| CA1013341A (en) | 1977-07-05 |
| JPS4961150A (sv) | 1974-06-13 |
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