SA522440330B1 - طرق لتصنيع خلايا تعبر عن مستقبل مستضد خيمري - Google Patents

طرق لتصنيع خلايا تعبر عن مستقبل مستضد خيمري

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Publication number
SA522440330B1
SA522440330B1 SA522440330A SA522440330A SA522440330B1 SA 522440330 B1 SA522440330 B1 SA 522440330B1 SA 522440330 A SA522440330 A SA 522440330A SA 522440330 A SA522440330 A SA 522440330A SA 522440330 B1 SA522440330 B1 SA 522440330B1
Authority
SA
Saudi Arabia
Prior art keywords
antigen receptor
chimeric antigen
methods
expressing cells
making chimeric
Prior art date
Application number
SA522440330A
Other languages
Arabic (ar)
English (en)
Inventor
بوريس انجيلز،
اليزابيث، دوروثي براتيكو،
اندرو برايس،
جينيفر بروجدون،
اتيليو بوندانزا،
لويس ترينور،
ميشيل، آر. جريني،
كارلا، باتريسيا، بينتو جيوماريس،
جلين درانوف،
اكسيو زهو،
اندرو، مارك ستين،
اكاش سوهوني،
سوجاتا شارما،
سيث كاربونيو،
اولجا كودراسي،
هيونجووك ليم،
انيشيا هاك،
مارك، هورست، بيتر هيلد،
Original Assignee
نوفارتيس ايه جى
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by نوفارتيس ايه جى filed Critical نوفارتيس ايه جى
Publication of SA522440330B1 publication Critical patent/SA522440330B1/ar

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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